Abstract:
:Data on patients with gallbladder cancer listed in the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute were reviewed. Between 1977 and 1986, 3038 patients were recorded in the Program. Histologic grade, histologic type, stage of disease, and vascular invasion were correlated with outcome. Compared with all other histologic types of cancer, papillary carcinomas had the most favorable prognosis. The 2-year survival rate for patients with papillary carcinoma was 47%. A correlation with survival existed between grade, stage of disease, and vascular invasion. The study confirmed that cancers of the gallbladder occur more often in older age groups and are more common in women. Almost 40% of cases are found at an advanced stage. For patients whose enolase tumor was limited to the gallbladder at the time of surgery, the 2-year survival rate was 45% and the 5-year rate was 32%.
journal_name
Cancerjournal_title
Cancerauthors
Henson DE,Albores-Saavedra J,Corle Ddoi
10.1002/1097-0142(19920915)70:6<1493::aid-cncr2820subject
Has Abstractpub_date
1992-09-15 00:00:00pages
1493-7issue
6eissn
0008-543Xissn
1097-0142journal_volume
70pub_type
杂志文章相关文献
CANCER文献大全abstract::Routine morphologic and cytochemical study of the leukemic cells of a 13-month-old child did not permit definitive determination of either a lymphoid or a myeloid cell origin. However, ultrastructural cytochemical analysis revealed platelet peroxidase (PPO) reactivity. The malignant cells expressed PPO in both unfixed...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19841001)54:7<1423::aid-cncr2820
更新日期:1984-10-01 00:00:00
abstract::Meningeal myeloid metaplasia (MM) is very rarely observed in patients with myelofibrosis. We report the occurrence of meningeal MM causing exophthalmus and fever in a patient with myelofibrosis secondary to polycythemia vera. A computerized tomography (CT) scan showed multiple intracranial and intraorbital enhancing m...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19881201)62:11<2346::aid-cncr282
更新日期:1988-12-01 00:00:00
abstract::Currently attention is focused on the testicle as a site of leukemic relapse. Leukemic involvement of the ovary has been described in several autopsy series with an incidence of 11-50% in patients with bone marrow relapse, but has rarely been reported during the clinical course of leukemia. In this report, four girls ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820801)50:3<587::aid-cncr28205
更新日期:1982-08-01 00:00:00
abstract:BACKGROUND:The authors analyzed the secretion of extracellular matrix-degrading proteinases, including urinary-type plasminogen activator (u-PA), matrix metalloproteinase-2 (MMP-2, gelatinase A), and MMP-9 (gelatinase B), by short term primary cultures of epithelial ovarian carcinoma cells derived from primary ovarian ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19971015)80:8<1457::aid-cn
更新日期:1997-10-15 00:00:00
abstract::Review of 61 surgically resected small hepatocellular carcinomas (HCC) less than or equal to 3 cm in diameter yielded a simple gross classification system of five types based on tumor shape, which is highly correlated with microscopic and clinical features, including prognosis. Type 1 (single nodular type) tumors (n =...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19870815)60:4<810::aid-cncr28206
更新日期:1987-08-15 00:00:00
abstract:BACKGROUND:Coagulopathies often are associated with malignant tumors. The pathogenesis of these complications in cancer is not clear. Host inflammatory (monocyte/macrophage) cell-mediated triggering of clotting activation has been suggested. METHODS:The objective of this study was to evaluate the role of neutrophil-de...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19931001)72:7<2134::aid-cncr2820
更新日期:1993-10-01 00:00:00
abstract::Trabecular carcinoma of the skin (Merkel cell tumor), a neoplasm of putative neural origin, must be differentiated from other small cell tumors primary or metastatic to skin. In order to provide more objective diagnostic criteria, four were examined using monoclonal antibodies against neurofilament proteins (NF) and a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850801)56:3<625::aid-cncr28205
更新日期:1985-08-01 00:00:00
abstract::To investigate the utility of thallium 201 (Tl-201) thyroid scintigraphy for the detection of thyroid malignancies, early and delayed Tl-201 scintigraphy was done in 70 consecutive patients with a clinically solitary cold (Iodine 123 [I-123]) nodule. Early Tl-201 scintigraphy had a sensitivity of 100% and a specificit...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19871201)60:11<2621::aid-cncr282
更新日期:1987-12-01 00:00:00
abstract:BACKGROUND:Bone morphogenetic proteins (BMP) induce ectopic bone formation in vivo and may play a role in normal bone development. In addition, bone morphogenetic activity, as measured in a bone-forming assay in immunodeficient, athymic nu/nu mice, is present in a proportion of osteosarcomas; this activity, which may b...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19940101)73:1<85::aid-cncr282073
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Treatment outcomes were analyzed for retromolar trigone squamous cell carcinoma. METHODS:Between June 1966 and August 2003, 99 patients were treated with radiotherapy alone (35 patients) or radiotherapy combined with surgery (64 patients). Followup ranged from 0.2 to 23.8 years (median, 3.3 yrs). All living...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21038
更新日期:2005-06-01 00:00:00
abstract::The efficacy of trioxifene mesylate, a new antiestrogen, in the management of advanced breast cancer was evaluated in 69 patients. Fifty-two patients were randomly allocated to dose schedules of 5 mg, 10 mg, and 20 mg orally twice daily. There were five complete responders (10%), 22 partial responders (42%), and 9 pat...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/1097-0142(19860101)57:1<40::aid-cncr282057
更新日期:1986-01-01 00:00:00
abstract:BACKGROUND:Forty patients with Stage II-III breast cancer with 10 or more positive axillary nodes were treated with mastectomy followed by four cycles of standard dose CAF (cytoxan, Adriamycin, 5-FU), followed by high dose cytoxan, cisplatin, carmustine (HDCT) with autologous bone marrow transplant support (ABMT), and ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19941201)74:11<2964::aid-cncr282
更新日期:1994-12-01 00:00:00
abstract::Chlorozotocin was administered by rapid intravenous infusion to 35 patients with advanced cancer on either single-day of five-consecutive-day schedules. Total doses per course ranged from 12.5 to 200 mg/m2. On either administration schedule, dose limiting toxicities were thrombocytopenia and leukopenia at total doses ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197906)43:6<2189::aid-cncr282043
更新日期:1979-06-01 00:00:00
abstract:BACKGROUND:The purpose of the current study was to determine the prevalence of low bone mineral density (BMD) (ie, osteopenia) and identify factors associated with low BMD in young adult survivors of childhood acute lymphoblastic leukemia (ALL). METHODS:Dual energy x-ray absorptiometry was used to evaluate BMD in 74 r...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23912
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Fludarabine plus busulfan (FB) and fludarabine plus melphalan (FM) are 2 widely used reduced-intensity conditioning (RIC) regimens for allogeneic hematopoietic stem cell transplantation (allo-SCT). METHODS:The current survey compared transplantation outcomes for a cohort of 394 acute myeloid leukemia (AML) ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.29163
更新日期:2015-04-01 00:00:00
abstract::Twelve patients with pulmonary neoplasms treated at the Fox Chase Cancer Center were found to have a syndrome of axillary-subclavian vein occlusion. Ten patients had non-small-cell lung carcinoma, one had small cell carcinoma, and one had mesothelioma. In eight patients, this vascular syndrome developed as a consequen...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19811015)48:8<1886::aid-cncr2820
更新日期:1981-10-15 00:00:00
abstract::A 20-year-old man with previously treated lymphoblastic lymphoma, a known T-cell disorder, developed progressive disease despite intensive combination chemotherapy with doxorubicin, vincristine, and prednisone. He was subsequently treated with a 21-day course of intravenous antithymocyte globulin at a dose of approxim...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820701)50:1<57::aid-cncr282050
更新日期:1982-07-01 00:00:00
abstract::This article describes the clinicopathologic features of six cases of uterine papillary serous carcinoma (UPSC), which developed several years after radiation therapy (RT) for cervical carcinoma. The possible etiologic role of radiation is discussed, and the literature on endometrial carcinomas developing after RT is ...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19920115)69:2<496::aid-cncr28206
更新日期:1992-01-15 00:00:00
abstract::Because of the rarity of the primary carcinoma of the female urethra, there has been limited experience of individual institutions in management of this disease. Treatment by radiation alone required radium implant skill in early cases and individualized consideration for integrating external and internal irradiation ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197809)42:3<1177::aid-cncr282042
更新日期:1978-09-01 00:00:00
abstract::The authors studied the expression of c-myc and ras family oncogene products in 43 cases of malignant lymphoma (ML) using the immunoperoxidase method. Unfixed frozen sections of lymph nodes from four patients with Hodgkin's disease and 39 with non-Hodgkin's lymphoma, together with normal lymph nodes, were studied by t...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19881115)62:10<2085::aid-cncr282
更新日期:1988-11-15 00:00:00
abstract:BACKGROUND:To the authors' knowledge, outcomes and prognostic tools have yet to be clearly defined in patients with metastatic renal cell carcinoma (mRCC) who are treated with immuno-oncology (IO) checkpoint inhibitors (programmed death-ligand 1 [PD-L1] inhibitors). In the current study, the authors aimed to establish ...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.31595
更新日期:2018-09-15 00:00:00
abstract:BACKGROUND:The authors analyzed the outcomes of patients treated with radiotherapy (RT) alone or combined with surgery for carcinoma of the salivary glands. METHODS:Between October 1964 and June 2003, 224 previously untreated patients were treated with curative intent with RT alone (n = 64) or combined with surgery (n...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21083
更新日期:2005-06-15 00:00:00
abstract:BACKGROUND:Overall, cervical cancer survival in the United States has been reported to be among the highest in the world, despite slight decreases over the last decade. Objective of the current study was to describe cervical cancer survival trends among US women and examine differences by race and stage. METHODS:This ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30906
更新日期:2017-12-15 00:00:00
abstract::Eleven patients with advanced soft tissue sarcoma were treated with whole body hyperthermia (41.8 degrees C-43.0 degrees C) for 2 hours, doxorubicin (45 mg/m2) at the beginning of peak temperature and cyclophosphamide (1000 mg/m2) 6 hours after doxorubicin. Warming was accomplished with a nylon and vinyl mesh water pe...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840615)53:12<2585::aid-cncr282
更新日期:1984-06-15 00:00:00
abstract::The potential of using a blood test enumerating oncofetal ferritin-bearing lymphocytes (FBL) as a biomarker for early breast cancer was further explored. Nine hundred women attending a high-risk breast cancer clinic and 2500 normal-risk women were physically examined and their blood drawn for FBL determination using a...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19890801)64:3<691::aid-cncr28206
更新日期:1989-08-01 00:00:00
abstract:BACKGROUND:African-American (AA) and white patients with early-stage disease who were treated with breast conservation therapy (BCT) were examined to detect differences in clinicopathologic features and outcomes as a function of race. METHODS:Clinical data from the charts of 2164 white and 207 AA patients treated with...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23881
更新日期:2008-11-01 00:00:00
abstract::The frequency and significance of hyperprolactinemia was studied in 21 consecutive, untreated male patients with bronchogenic carcinoma. Seven patients (33%) were found to have elevated serum prolactin (hPRL) levels. No correlation was demonstrated between increased hPRL levels, tissue histology, or tumor burden. L-do...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197908)44:2<676::aid-cncr2820440
更新日期:1979-08-01 00:00:00
abstract::For men diagnosed with clinically localized prostate cancer, definitive therapy with radical prostatectomy, external beam radiation therapy, or brachytherapy offers a high chance of cure. Currently, there are insufficient data to recommend 1 treatment approach over another, leaving physicians and patients to decide ba...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.24344
更新日期:2009-07-01 00:00:00
abstract::A familial cancer aggregation comprising sarcomas, brain tumors, leukemias, and carcinomas of breast, larynx, lung, adrenal, cortex, and other sites has been studied from a pathologic--genetic standpoint. Based upon sibships segregating for cancer, the genetic segregation parameter is estimated to be 45.6 +/- 11% whi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197805)41:5<2055::aid-cncr282041
更新日期:1978-05-01 00:00:00
abstract:BACKGROUND:Irinotecan-based chemotherapy regimens are 1 option for treatment of metastatic colorectal cancer (mCRC). The authors report the safety and efficacy of such regimens in elderly patients using a large phase III trial (bolus, infusional, or capecitabine with camptostar-celecoxib [BICC-C]) cohort. METHODS:In p...
journal_title:Cancer
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/cncr.24305
更新日期:2009-06-15 00:00:00