Abstract:
:Combined modality therapy consisting of CHOP-Bleo (cyclophosphamide, Adriamycin [doxorubicin], vincristine (Oncovin), prednisone, and bleomycin) and limited-field radiotherapy was given to 47 patients with Stage III and IIIE diffuse large cell lymphomas. Overall 5-year survival and disease-free survival figures are 64% and 53%, respectively. Twenty-nine patients achieved and maintained a complete remission during treatment; 92% of these patients are alive at 5 years, and 87% are disease-free. Prognostic factors were assessed for the entire group. Age, "B" symptoms, extranodal involvement, and extensive abdominal involvement had little effect on survival. However, the presence of mediastinal involvement and extensive abdominal involvement was associated with a poor response rate and survival.
journal_name
Cancerjournal_title
Cancerauthors
Velasquez W,Fuller LM,Oh KK,Hagemeister FB,Sullivan JA,Manning JT,Shullenberger CCdoi
10.1002/1097-0142(19840401)53:7<1478::aid-cncr2820subject
Has Abstractpub_date
1984-04-01 00:00:00pages
1478-83issue
7eissn
0008-543Xissn
1097-0142journal_volume
53pub_type
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