Cytologic examination of pancreatic juice for differential diagnosis of benign and malignant mucin-producing tumors of the pancreas.

Abstract:

BACKGROUND:A new clinical type of pancreatic tumor, the mucin-producing tumor, has been recognized recently. However, it is not always easy to distinguish benign from malignant tumors preoperatively. In this study, three different methods of differentiating mucin-producing tumors of the pancreas were compared. METHODS:Endoscopic ultrasonography, endoscopic retrograde pancreatography, and cytologic examination of pancreatic juice were performed in 14 patients who had mucin-producing pancreatic tumors (11 carcinomas and 3 adenomas). Pancreatic juice was collected endoscopically without papillotomy. RESULTS:The sensitivity, specificity, and overall accuracy of endoscopic ultrasonography were 82%, 90%, and 79%, respectively; those of endoscopic retrograde pancreatography were 91%, 91%, and 86%; and those of cytologic examination were 91%, 100%, and 93%. CONCLUSION:Cytologic examination of pancreatic juice was the best of these three methods for differentiating benign from malignant mucin-producing pancreatic tumors.

journal_name

Cancer

journal_title

Cancer

authors

Uehara H,Nakaizumi A,Iishi H,Tatsuta M,Kitamra T,Okuda S,Ohigashi H,Ishikawa O,Takenaka A,Ishiguro S

doi

10.1002/1097-0142(19940801)74:3<826::aid-cncr28207

subject

Has Abstract

pub_date

1994-08-01 00:00:00

pages

826-33

issue

3

eissn

0008-543X

issn

1097-0142

journal_volume

74

pub_type

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