Paratesticular sarcoma in childhood and adolescence. A report from the Intergroup Rhabdomyosarcoma Studies I and II, 1973-1983.

abstract：BACKGROUND:Parathyroid hormone-related peptide (PTHrP) is a tumor-derived circulating factor that has been associated with hypercalcemia of malignancy. The role of PTHrP as a prognostic indicator remains unclear. Studies suggest that it may function as a growth factor; and, recently, the ability of PTHrP to induce cyto...

journal_title：Cancer

authors： Deans C,Wigmore S,Paterson-Brown S,Black J,Ross J,Fearon KC

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:The performance of cytologic screening and its correlation with histology and polymerase chain reaction (PCR) detection of human papillomavirus (HPV) DNA have not been evaluated in populations with a low prevalence of anal intraepithelial neoplasia (AIN). The objective of the current study was to analyze the...

journal_title：Cancer

authors： Etienney I,Vuong S,Si-Mohamed A,Fléjou JF,Atienza P,Bauer P,Cytological Diaconesses Group.

更新日期：2012-12-15 00:00:00

abstract：BACKGROUND:The demonstration of the monoclonality of immunoglobulin heavy chain (IgH) gene rearrangement is an indispensable method for the diagnosis of B-cell lymphoma as well as histocytochemical analysis. For the detection of IgH gene rearrangement, the extraction of DNA from a homogenous cell population is necessar...

journal_title：Cancer

authors： Orba Y,Tanaka S,Nishihara H,Kawamura N,Itoh T,Shimizu M,Sawa H,Nagashima K

更新日期：2003-08-25 00:00:00

abstract：:There are three principal disturbances in bone remodelling that occur in neoplasia affecting the skeleton. The first is an increase in bone turnover that in solid tumors may be confined to sites of metastases or be a generalized phenomenon, most likely related to the secretion of parathyroid hormone-related protein. I...

journal_title：Cancer

authors： Kanis JA,McCloskey EV

更新日期：1997-10-15 00:00:00

abstract：:Postmenopausal patients with metastatic breast cancer were treated with medroxyprogesterone acetate (MPA) (Clinovir) in dosages between 500 and 1500 mg orally per day. The relation of MPA plasma concentrations and endocrine effects were studied in a longitudinal fashion. MPA exerted suppressive effects on the basal an...

journal_title：Cancer

authors： Blossey HC,Wander HE,Koebberling J,Nagel GA

更新日期：1984-09-15 00:00:00

abstract：:Higher serum iron and ferritin levels noted in hepatitis B antigen (HBAg) carriers than in noncarriers suggests that virus might actively replicate in hepatocytes, stimulate ferritin synthesis, and result in increased liver iron stores. A comparative semiquantitative study of immunohistochemical ferritin (0-12) and he...

journal_title：Cancer

authors： Cohen C,Berson SD,Shulman G,Budgeon LR

更新日期：1985-11-01 00:00:00

abstract：:Histologic, histochemical, immunocytochemical, and ultrastructural features of two cardiac myxomas containing glandular elements are reported. Glandular elements in both cases stained positively with both mucicarmine and periodic acid-Schiff reagent with diastase pretreatment (DPAS). Immunoperoxidase studies demonstra...

journal_title：Cancer

authors： Goldman BI,Frydman C,Harpaz N,Ryan SF,Loiterman D

更新日期：1987-05-15 00:00:00

abstract：BACKGROUND:Gastrointestinal stromal tumors (GISTs) historically were grouped with leiomyosarcomas (LMSs) based on their morphologic similarities; however, recently, GIST was established unequivocally as a distinct type of sarcoma based on its molecular features and response to imatinib treatment. METHODS:To gain furth...

journal_title：Cancer

authors： Ylipää A,Hunt KK,Yang J,Lazar AJ,Torres KE,Lev DC,Nykter M,Pollock RE,Trent J,Zhang W

更新日期：2011-01-15 00:00:00

abstract：BACKGROUND:hMLH1, the human MutL homologue, has been linked to microsatellite instability (MSI) in gastrointestinal tumors. However, to the authors' knowledge, the role of hMLH1, the other mismatch repair genes (MMR), and MSI in ovarian carcinoma has not been well defined. The purpose of the current study was to determ...

journal_title：Cancer

authors： Geisler JP,Goodheart MJ,Sood AK,Holmes RJ,Hatterman-Zogg MA,Buller RE

更新日期：2003-11-15 00:00:00

abstract：BACKGROUND:Cytogenetics and multicolor flow cytometry (MFC) are useful tools for monitoring outcome of treatment in acute myeloid leukemia (AML). However, no data are available regarding the meaning of results when the 2 tests do not agree. METHODS:The authors of this report analyzed 1464 pairs of concurrent cytogenet...

journal_title：Cancer

authors： Fang M,Storer B,Wood B,Gyurkocza B,Sandmaier BM,Appelbaum FR

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Nude mice with xenografted human tumors is the most exploited animal model used to elucidate the efficacy of experimental radioimmunolocalization and radioimmunotherapy. These animals accept transplants and are generally considered immunologically inert with regard to cell-mediated and humoral immune respons...

journal_title：Cancer

authors： Stigbrand T,Ullén A,Sandström P,Rathsman S,Rossi Norrlund R,Arlestig L,Riklund Ahlström K,Hietala SO

更新日期：1997-12-15 00:00:00

abstract：:Phytohemagglutinin (PHA) stimulates blastic transformation of normal lymphocytes in vitro and when injected intradermally produces a skin response histologically similar to a delayed hypersensitivity reaction. We investigated the skin test responses to PHA, mumps, candida, and varidase (SK-SD) and the PHA-induced lymp...

journal_title：Cancer

authors： Zuckerman KS,LoBuglio AF

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:Although grading has prognostic significance for many tumor types, a prognostically significant grading system for lung adenocarcinoma has not yet been established. The aim of this study was to evaluate histologic characteristics included in tumor grading systems, establish optimal cutoff values that have th...

journal_title：Cancer

authors： Barletta JA,Yeap BY,Chirieac LR

更新日期：2010-02-01 00:00:00

abstract：:Actuarial progression-free survival rate at 5 years of a series of 34 patients with medulloblastoma treated by combined surgery, radiotherapy, and chemotherapy was 71%. No relapses were observed in 14 patients followed for more than 5 years. Treatment consisted of a short postoperative course of vincristine (VCR) and ...

journal_title：Cancer

authors： Bellani FF,Gasparini M,Lombardi F,Zucali R,Luccarelli G,Migliavacca F,Moise S,Nicola G

更新日期：1984-11-01 00:00:00

abstract：:The trends in head and neck cancer incidence and smoking prevalence are reviewed, discussing where such trends parallel but also how and why they may not. In the U.S., public health efforts at tobacco control and education have successfully reduced the prevalence of cigarette smoking, resulting in a lower incidence of...

journal_title：Cancer

authors： Sturgis EM,Cinciripini PM

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Fine-needle aspiration biopsy (FNA) has been successful in diagnosing epithelial lesions of the breast. Its role in the evaluation of spindle cell and mesenchymal lesions of the breast, which include a variety of benign and malignant conditions, is less clear. This article discusses the cytologic features an...

journal_title：Cancer

authors： Chhieng DC,Cangiarella JF,Waisman J,Fernandez G,Cohen JM

更新日期：1999-12-25 00:00:00

abstract：:Malignant struma ovarii is a very rare tumor, consisting of a struma ovarii with malignant change. Only 17 examples with metastases have previously been reported. We present a case which involved both ovaries and produced multiple metastases. Microscopy and ultrastructure were identical to a mixed papillary and follic...

journal_title：Cancer

authors： Pardo-Mindan FJ,Vazquez JJ

更新日期：1983-01-15 00:00:00

abstract：:Survivors of pediatric and young adult cancers remain at risk for subsequent diseases, including those related to human papillomavirus (HPV) infection. Prevention of HPV acquisition through vaccination has become possible over the last decade. HPV vaccines have been shown to be safe and effective, yet rates of vaccina...

journal_title：Cancer

authors： Temkin SM,Seibel NL

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:To the authors' knowledge, the long term follow-up of patients with carcinoma in situ of the urinary bladder is limited. METHODS:The authors studied 138 patients diagnosed with urothelial carcinoma in situ of the bladder at the Mayo Clinic between 1972-1979. All the histologic slides were reviewed and fulfi...

journal_title：Cancer

authors： Cheng L,Cheville JC,Neumann RM,Leibovich BC,Egan KS,Spotts BE,Bostwick DG

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:The median survival for patients with glioblastoma is reported to be 12 months. To improve the outcome for glioblastoma patients, the authors evaluated the therapeutic efficacy of preirradiation gemcitabine chemotherapy followed by standard radiotherapy. METHODS:Twenty-one patients with newly diagnosed glio...

journal_title：Cancer

authors： Weller M,Streffer J,Wick W,Kortmann RD,Heiss E,Küker W,Meyermann R,Dichgans J,Bamberg M

更新日期：2001-01-15 00:00:00

abstract：BACKGROUND:Neuroblastoma is the most common malignancy among infants, but risk factors remain poorly understood. Because most patients present in the first few years of life, it has been hypothesized that prenatal and perinatal exposures may contribute to the pathogenesis of neuroblastoma. METHODS:A population-based c...

journal_title：Cancer

authors： Chow EJ,Friedman DL,Mueller BA

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Intracranial meningiomas are common and comprise 20% of all primary brain tumors. Meningiomas infrequently metastasize; however, to the authors' knowledge there are limited data regarding the spread of disease through cerebrospinal fluid (CSF). METHODS:Eight of 200 consecutive patients (4%) with meningiomas...

journal_title：Cancer

authors： Chamberlain MC,Glantz MJ

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:p53 gene mutation and p53 protein accumulation are common in human cancer. However, their clinical significance is controversial and p53 accumulation may not correlate with gene mutation. The current study investigates the occurrence of p53 alterations in esophageal carcinoma, the correlation between the ana...

journal_title：Cancer

authors： Coggi G,Bosari S,Roncalli M,Graziani D,Bossi P,Viale G,Buffa R,Ferrero S,Piazza M,Blandamura S,Segalin A,Bonavina L,Peracchia A

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Treatment of localized prostate carcinoma (LPC) using radiotherapy (RT) can induce disturbances in a patient's quality of life (QOL) and urinary and intestinal function. Late symptoms and QOL were evaluated in a randomized trial between RT and deferred treatment (DT). METHODS:Quality of life was evaluated w...

journal_title：Cancer

authors： Fransson P,Damber JE,Tomic R,Modig H,Nyberg G,Widmark A

更新日期：2001-12-15 00:00:00

abstract：:Twenty-four patients with various solid tumors including metastatic liver cancer and cancer of the lung, gallbladder, and pancreas were treated with a lipophilic macromolecular drug, copoly(styrene-maleic acid) conjugated neocarzinostatin (SMANCS). The drug was dissolved in a lipid contrast medium Lipiodol and adminis...

journal_title：Cancer

authors： Konno T,Maeda H,Iwai K,Maki S,Tashiro S,Uchida M,Miyauchi Y

更新日期：1984-12-01 00:00:00

abstract：:Seven adults had a distinct clinicopathologic type of lymphoproliferative disorder of the bone marrow. All patients presented with weakness and pancytopenia; no evidence of gross extramedullary involvement was found. In 5 cases severe and prolonged bone marrow hypoplasia was associated with combination chemotherapy; 1...

journal_title：Cancer

authors： Barton JC,Conrad ME,Vogler LB,Parmley RT

更新日期：1980-10-15 00:00:00

abstract：:Multifocal osteosarcoma with unique patho-biological features in a 23-year old white male is reported. The natural history and classification of multiple osteosarcomas are reviewed. A proposal is presented for evaluation of the multicentric origin in future cases. ...

journal_title：Cancer

authors： Mahoney JP,Spanier SS,Morris JL

更新日期：1979-11-01 00:00:00

abstract：:A 30-year-old man underwent orchiectomy in 1962 for a testicular carcinoma composed of choriocarcinomatous and teratocarcinomatous elements. Bilateral pulmonary metastases regressed completely on combination chemotherapy. However, a cerebral metastasis developed in 1963 and caused severe neurologic signs. At craniotom...

journal_title：Cancer

authors： Stolinsky DC

更新日期：1981-03-01 00:00:00

abstract：:In a county hospital, 217 patients were operated on for suspected cancer of the pancreas (186 patients) and periampullary structures (31 patients). The surgeons' philosophy was to avoid biopsy of the pancreas whenever possible, they often performed radical resection based on clinical judgment alone (8% of the resectio...

journal_title：Cancer

authors： Lee YT

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:CD133 is a specific surface marker for bone marrow-derived circulating endothelial progenitors, which are vital in postnatal physiologic and pathologic (eg, tumor) angiogenesis. In this study, the authors examined whether increased levels of expression of CD133 messenger RNA (mRNA) in peripheral blood predic...

journal_title：Cancer

authors： Lin EH,Hassan M,Li Y,Zhao H,Nooka A,Sorenson E,Xie K,Champlin R,Wu X,Li D

更新日期：2007-08-01 00:00:00