Virtual microscopy for cytology proficiency testing: are we there yet?

abstract：:The prolonged administration of bisphosphonates can reduce the frequency of morbid skeletal events in patients with metastatic breast carcinoma or multiple myeloma. The development of more potent bisphosphonates will simplify current therapeutic schemes and could improve the therapeutic effectiveness of bisphosphonate...

journal_title：Cancer

authors： Body JJ

更新日期：1997-10-15 00:00:00

abstract：:Effective screening for occult ovarian cancer will require a strategy that is both sensitive and specific. Preliminary data suggest that CA 125 is elevated at diagnosis in a majority of patients with ovarian cancer. Although CA 125 is sufficiently specific to prompt its evaluation as one component of a strategy to det...

journal_title：Cancer

authors： Bast RC Jr,Knauf S,Epenetos A,Dhokia B,Daly L,Tanner M,Soper J,Creasman W,Gall S,Knapp RC

更新日期：1991-10-15 00:00:00

abstract：BACKGROUND:To determine whether high-risk patients with hematuria receive evaluation according to guideline recommendations. METHODS:We recently performed a screening study for bladder cancer using a urine-based tumor marker in 1502 subjects at high risk based on aged > or = 50 years, > or = 10-year smoking history, a...

journal_title：Cancer

authors： Elias K,Svatek RS,Gupta S,Ho R,Lotan Y

更新日期：2010-06-15 00:00:00

abstract：:Primary adenocarcinoma of the duodenum is rare. An extensive experience with fiberoptic esophagogastro-duodenoscopy in our institution has indicated that duodenal neoplasms may be more frequent than suspected and are readily diagnosed by this modality. With this mind, clinical, pathological, diagnostic and therapeutic...

journal_title：Cancer

authors： Spira IA,Ghazi A,Wolff WI

更新日期：1977-04-01 00:00:00

abstract：:Renal cell carcinoma (RCC) has remained refractory to substantive change of its natural history despite intervention with a number of therapeutic modalities. Alpha interferons leukocyte interferon alpha [HuIFN-alpha (Le)] and lymphoblastoid interferon alpha [HuIFN-alpha (Ly)] initially were shown to produce regression...

journal_title：Cancer

authors： Neidhart JA

更新日期：1986-04-15 00:00:00

abstract：:A case of transfusion-induced graft-versus-host disease (GVHD) occurring in a 31-year-old female with Hodgkin's disease in complete remission is reported. Clinical features are similar to 19 other reported cases of transfusion-induced GVHD associated with malignant lymphoma. The lack of relationship with underlying hi...

journal_title：Cancer

authors： Spitzer TR,Cahill R,Cottler-Fox M,Treat J,Sacher R,Deeg HJ

更新日期：1990-12-01 00:00:00

abstract：:METHODS. Social class differences in colon cancer survival were studied in 3147 patients with colon cancer diagnosed in Finland from 1979-1982. Of these patients, 2969 were eligible for survival analysis. RESULTS. A clear social class gradient in colon cancer survival was detected. The difference in the age-adjusted r...

journal_title：Cancer

authors： Auvinen A

更新日期：1992-07-15 00:00:00

abstract：BACKGROUND:The Edmonton Symptom Assessment Scale (ESAS) is a nine-item patient-rated symptom visual analogue scale developed for use in assessing the symptoms of patients receiving palliative care. The purpose of this study was to validate the ESAS in a different population of patients. METHODS:In this prospective stu...

journal_title：Cancer

authors： Chang VT,Hwang SS,Feuerman M

更新日期：2000-05-01 00:00:00

abstract：:Amyloid as defined by positive Congo red green birefringence and STB red birefringence was observed in the stroma of a tubular carcinoma of minor salivary gland origin. The amyloid exhibited additional histochemical characteristics of immunamyloid, viz., positive DMAB-nitrate and DC-reactions and spontaneous autofluor...

journal_title：Cancer

authors： David R,Buchner A

更新日期：1978-05-01 00:00:00

abstract：:Distant nontraumatic clostridial myonecrosis in association with malignancy is an uncommon disorder, with only 14 well-documented cases previously reported in the English literature. Clostridium perfringens and C. septicum are the most common organisms, usually gaining access to the circulation through an ulcerated le...

journal_title：Cancer

authors： Kaiser CW,Milgrom ML,Lynch JA

更新日期：1986-02-15 00:00:00

abstract：:For 52 patients with depressed adenomas of the stomach, histopathologic studies were done on 56 tumors and for 43 of them, histochemical and immunohistochemical features were examined. In addition, nondepressed adenomas (n = 57) and the depressed type of early gastric adenocarcinomas of the well-differentiated variety...

journal_title：Cancer

authors： Xuan ZX,Ambe K,Enjoji M

更新日期：1991-05-01 00:00:00

abstract：:In a study conducted by the Eastern Cooperative Oncology Group, 51 evaluable women with advanced ovarian carcinoma were randomized to either abdominal radiation therapy alone, chlorambucil alone, or to a combination of radiation therapy and chlorambucil by members of the Eastern Cooperative Oncology Group. Provision w...

journal_title：Cancer

authors： Miller SP,Brenner S,Horton J,Stolbach L,Shnider BI,Pocock S

更新日期：1975-11-01 00:00:00

abstract：:Primary lymphomas of the small intestine (PIL) show definite racial and geographic distribution. Clinical and laboratory data on 132 patients with PIL treated and followed up over a 14-year period in Baghdad, Iraq, are presented. Based on the pattern of involvement of the bowel and the histopathologic appearance of th...

journal_title：Cancer

authors： Al-Bahrani ZR,Al-Mondhiry H,Bakir F,Al-Saleem T

更新日期：1983-11-01 00:00:00

abstract：BACKGROUND:Pelvic irradiation to patients with prostate cancer is accompanied by urinary and intestinal reactions. In men older than 60 years, treatment-induced problems should be evaluated in relation to problems in an age-matched nonirradiated population. METHODS:In the present study, problems in the urinary tract a...

journal_title：Cancer

authors： Widmark A,Fransson P,Tavelin B

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to determine the independent prognostic variables in a well documented subset of 216 patients with localized primary malignant fibrous histiocytomas (MFH). METHODS:Between the years 1980 and 1989, 216 patients with localized, primary (International Union Against Cancer [UICC]/A...

journal_title：Cancer

authors： Le Doussal V,Coindre JM,Leroux A,Hacene K,Terrier P,Bui NB,Bonichon F,Collin F,Mandard AM,Contesso G

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Older women are less likely than younger women to receive definitive care for a new diagnosis of breast cancer, but the reasons are not well understood. Although coordination of referral among specialists is an important component of quality of care, it has not been studied as a factor that contributes to ob...

journal_title：Cancer

authors： Thwin SS,Fink AK,Lash TL,Silliman RA

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:The first step of colorectal carcinoma spread depends on the ability of the tumor cells to degrade and invade the extracellular matrix (ECM). The objectives of the current study were to evaluate the serum pattern of laminin, C-terminal peptide of Type I (PIP), and N-terminal peptide of Type III (PIIIP) proco...

journal_title：Cancer

authors： Plebani M,Basso D,Roveroni G,De Paoli M,Galeotti F,Corsini A

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:For the moment, there is uncertainty about the usefulness of early treatment of localized prostate carcinoma, uncertainty about whether some patients with early cancer can be managed expectantly, and uncertainty about how such patients might be recognized. METHODS:The authors studied serial values of prosta...

journal_title：Cancer

authors： Vollmer RT,Egawa S,Kuwao S,Baba S

更新日期：2002-03-15 00:00:00

abstract：:A case of gastric plasmacytoma is reported in an 81-year-old woman. Immunofluorescent and immunoelectrophoretic studies showed that the tumor cells produced IgM-lambda molecules, whereas no monoclonal immunoglobulin could be detected both in the serum and in the urine. Of more than 60 reported cases of gastric plasmac...

journal_title：Cancer

authors： Funakoshi N,Kanoh T,Kobayashi Y,Miyake T,Uchino H,Ochi K

更新日期：1984-08-15 00:00:00

abstract：BACKGROUND:Inferior vena cava obstruction (IVCO) is a poorly characterized complication of metastatic germ cell tumor (GCT). The authors identified 31 cases to describe the clinical features, radiologic findings, complications, and treatment of this clinical entity. METHODS:Patients with GCT and IVCO were identified f...

journal_title：Cancer

authors： Hassan B,Tung K,Weeks R,Mead GM

更新日期：1999-02-15 00:00:00

abstract：BACKGROUND:The aims of this study were to compare human epidermal growth factor receptor 2 (HER2) results between immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH), and to investigate the clinicopathological characteristics and outcomes according to their results. METHODS:Using consecutive tissu...

journal_title：Cancer

authors： Park S,Park HS,Koo JS,Yang WI,Kim SI,Park BW

更新日期：2012-02-15 00:00:00

abstract：BACKGROUND:An intensive in-patient Phase II study of continuous infusion recombinant human interleukin-2 (rhIL-2) 3 X 10(6) Roche units (9 MIU/m2)/day plus intramuscular injection of interferon-alpha-2a (rIFN-alpha-2a) 5 x 10(6) U/m2/day, four consecutive days per week, was performed to determine whether four consecuti...

journal_title：Cancer

authors： Eton O,Talpaz M,Lee KH,Rothberg JM,Brell JM,Benjamin RS

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:The usefulness of fine-needle aspiration biopsy (FNAB) for the histologic subtyping of specific sarcomas still is somewhat controversial but is becoming increasingly popular in the U.S. METHODS:To determine the accuracy and usefulness of FNAB in the differential diagnosis of myxoid sarcoma, the authors retr...

journal_title：Cancer

authors： Kilpatrick SE,Ward WG,Bos GD

更新日期：2000-06-25 00:00:00

abstract：BACKGROUND:The results and consequences of genetic testing in a family with familial medullary thyroid carcinoma (FMTC) are described. METHODS:In the screening of relatives, serum calcitonin is replaced by RET mutation analysis that was performed in families suspected of hereditary medullary thyroid carcinoma (MTC). I...

journal_title：Cancer

authors： Hansen HS,Torring H,Godballe C,Jäger AC,Nielsen FC

更新日期：2000-08-15 00:00:00

abstract：BACKGROUND:Low frequency epithelial cells in bone marrow from colorectal carcinoma patients are associated with an increased risk of recurrence and decreased survival. Current immunohistochemical approaches to detect epithelial cells in bone marrow aspirates rely on antibodies against cytokeratin 18 (CK18). The predict...

journal_title：Cancer

authors： Litle VR,Warren RS,Moore D 2nd,Pallavicini MG

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Currently, there is very low-quality evidence available regarding benefit of surgical resection of the primary tumor (SRPT), in patients with stage IV colorectal cancer (CRC). In the absence of randomization, the reported benefit may reflect selection of younger and healthier patients with good performance s...

journal_title：Cancer

authors： Ahmed S,Leis A,Fields A,Chandra-Kanthan S,Haider K,Alvi R,Reeder B,Pahwa P

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:The primary purpose of this study was to establish the maximum tolerated dose (MTD) of intravenous melphalan in combination with paclitaxel and cisplatin plus granulocyte-colony stimulating factor (G-CSF) in patients with suboptimal advanced epithelial ovarian carcinoma or primary peritoneal carcinoma. METH...

journal_title：Cancer

authors： Gershenson DM,Morris M,Burke TW,Levenback C,Wolf J,Lee JJ,Thall PF,Atkinson EN,Silva EG,Wharton JT

更新日期：1999-12-01 00:00:00

abstract：:Two groups of children with refractory acute lymphoblastic leukemia were treated with a regimen of methotrexate (MTX) and asparaginase (Asn'ase) based on studies of the effect of MTX in vitro on human lymphoblasts exposed to Asn'ase. Induction therapy in 12 children produced 4 complete remissions, 3 partial remissions...

journal_title：Cancer

authors： Lobel JS,O'Brien RT,McIntosh S,Aspnes GT,Capizzi RL

更新日期：1979-03-01 00:00:00

abstract：BACKGROUND:The increasing incidence of human papillomavirus (HPV)-related head and neck squamous cell carcinoma (HNSCC) highlights the need for simple and effective tools to evaluate head and neck lesions and their HPV status. The main objective of the current study was to investigate the association between abnormal c...

journal_title：Cancer

authors： Donà MG,Giuliani M,Vocaturo A,Spriano G,Pichi B,Rollo F,Ronchetti L,Covello R,Pescarmona E,Benevolo M

更新日期：2014-11-15 00:00:00

abstract：:New approaches are needed in the treatment of advanced breast cancer. In vitro studies have shown that recombinant tumor necrosis factor (TNF) is a growth inhibitor for the MCF-7, ZR-75-1, and BT-20 human breast cancer cell lines. Based on these considerations, the Southwest Oncology Group performed a Phase II trial o...

journal_title：Cancer

authors： Budd GT,Green S,Baker LH,Hersh EP,Weick JK,Osborne CK

更新日期：1991-10-15 00:00:00