Abstract:
:In a study conducted by the Eastern Cooperative Oncology Group, 51 evaluable women with advanced ovarian carcinoma were randomized to either abdominal radiation therapy alone, chlorambucil alone, or to a combination of radiation therapy and chlorambucil by members of the Eastern Cooperative Oncology Group. Provision was made for crossover therapy for patients who were nonresponders to a single modality of treatment. Parameters followed included objective and subjective response rates and patient survival. The total response rate was 51%, with no significant difference among the three treatment regimens. Regarding survival, radiation therapy alone was significantly superior to the other regimens, with an average survival of 94.9 weeks. Best results were obtained in patients with normal performance status; for this group, radiation therapy alone offered the best chance for prolonged survival.
journal_name
Cancerjournal_title
Cancerauthors
Miller SP,Brenner S,Horton J,Stolbach L,Shnider BI,Pocock Sdoi
10.1002/1097-0142(197511)36:5<1625::aid-cncr282036subject
Has Abstractpub_date
1975-11-01 00:00:00pages
1625-30issue
5eissn
0008-543Xissn
1097-0142journal_volume
36pub_type
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