Abstract:
:A patient is described with chronic myelogenous leukemia (CML) and an unusual karyotype 46XY,t(Y;12) (q11;p12), whose clinical course was complicated by T-cell lymphoma 5 years later. At that time bone marrow cells showed an additional karyotypic abnormality 46XY,t(Y;12) (q11;p12) del(7) (pter-p21), which remained unchanged until blastic transformation of the CML 8 months later. The bone marrow biopsy specimen, which revealed the blastic transformation of the CML, also showed evidence for localization of T-cell lymphoma. This case, added to two previously reported cases of the concurrence of CML and T-cell lymphoma, suggests a relationship between the two diseases, which is discussed.
journal_name
Cancerjournal_title
Cancerauthors
Blonk MC,van der Valk P,Beverstock GC,Ossenkoppele GJdoi
10.1002/1097-0142(19900915)66:6<1198::aid-cncr2820subject
Has Abstractpub_date
1990-09-15 00:00:00pages
1198-203issue
6eissn
0008-543Xissn
1097-0142journal_volume
66pub_type
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