Prolonged remissions in adults with acute leukemia following late intensification chemotherapy and immunotherapy.

abstract：:Six breast cancer patients were treated recently for renal insufficiency secondary to neoplasic involvement of the ureters. This complication usually occurs in long standing hormonal-dependent breast cancer with bone metastases. Diagnosis was performed by abdominal echography. Ureteral catheterization or percutaneous ...

journal_title：Cancer

authors： Recloux P,Weiser M,Piccart M,Sculier JP

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:There is no consistent definition at what age patients with non-Hodgkin lymphoma (NHL) are considered "elderly." This might hamper well balanced decisions with respect to treatment. METHODS:From a population-based NHL registry the age groups younger than 60 years, 60-64 years, 65-69 years, 70-74 years, and ...

journal_title：Cancer

authors： Maartense E,Kluin-Nelemans HC,le Cessie S,Kluin PM,Snijder S,Noordijk EM

更新日期：2000-12-15 00:00:00

abstract：BACKGROUND:Patients with multiple myeloma (MM) have increased bone marrow angiogenesis, a low plasma cell labeling index, and multidrug resistance (the primary cause of chemotherapy failure). MM patients receiving the vincristine, doxorubicin, and dexamethasone (VAD) regimen develop resistance and cardiac and steroid t...

journal_title：Cancer

authors： Hussein MA,Wood L,Hsi E,Srkalovic G,Karam M,Elson P,Bukowski RM

更新日期：2002-11-15 00:00:00

abstract：:The combination of conservation surgery and radiation therapy for early breast cancer is gaining acceptance as an alternative to radical mastectomy. This article reviews the results of randomized trials showing that there is no advantage to a radical mastectomy in patients with early breast cancer. In addition, the ar...

journal_title：Cancer

authors： Montague ED,Ames FC,Schell SR,Romsdahl MM

更新日期：1984-12-01 00:00:00

abstract：:To evaluate the potential teratogenicity and mutagenicity of modern cancer treatment, the authors enumerated from a cooperative clinical trial group 133 pregnancies in 66 women with malignant neoplasms (53% with Hodgkin's disease, 26% with other lymphomas and leukemia, and 21% with solid tumors). The gestations were d...

journal_title：Cancer

authors： Mulvihill JJ,McKeen EA,Rosner F,Zarrabi MH

更新日期：1987-09-01 00:00:00

abstract：:Human cases autopsied at the Department of Pathology, University of Tokyo, were studied to investigate the chronologic changes in the relationship between cigarette smoking and lung cancer occurrence. The results obtained were as follows: (1) it was confirmed that the incidence of lung cancer was significantly higher ...

journal_title：Cancer

authors： Mori W,Sakai R

更新日期：1984-09-15 00:00:00

abstract：:Almost all patients with prostatic cancer will eventually escape the control of the first-line endocrine therapy and relapse. This escape is attributed to selecting and/or cloning preexisting or de novo appearing hormone-independent or resistant cell lines and occurs in most patients after a median time of 12 to 18 mo...

journal_title：Cancer

authors： Mahler C,Denis L

更新日期：1992-07-01 00:00:00

abstract：:From 1954 through 1982, 57 patients with invasive, distal rectal cancer had a full-thickness local excision with curative intent. Prognostic criteria and need for further treatment were based on the histopathologic results of the operative specimen. The overall 5-year survival rate was 83.4%. The rectal cancer-specifi...

journal_title：Cancer

authors： DeCosse JJ,Wong RJ,Quan SH,Friedman NB,Sternberg SS

更新日期：1989-01-15 00:00:00

abstract：:Three cases of pulmonary lymphangiomyomatosis are described, with emphasis on the ultrastructural changes. The clinicopathologic features corresponded to those previously described. Each patient was a female in the reproductive years; breathlessness and recurrent pneumothoraces were the predominant clinical features. ...

journal_title：Cancer

authors： Basset F,Soler P,Marsac J,Corrin B

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:Cyclin-dependent kinases (CDK) and cyclins constitute the subunits of the maturation-promoting factor that controls the process of cell division. High levels of these proteins have been reported in human malignancies of the stomach, colon, breast, and lung, and have been implicated in aberrant cell division ...

journal_title：Cancer

authors： Kallakury BV,Sheehan CE,Ambros RA,Fisher HA,Kaufman RP Jr,Ross JS

更新日期：1997-08-15 00:00:00

abstract：BACKGROUND:A somatic gain-of-function mutation of the Janus kinase 2 (JAK2) gene has been identified in chronic myeloproliferative disorders, which appear to have a sporadic occurrence in most individuals. The authors studied the biologic significance of the JAK2 (V617F) mutation in familial myeloproliferative disorder...

journal_title：Cancer

authors： Rumi E,Passamonti F,Pietra D,Della Porta MG,Arcaini L,Boggi S,Elena C,Boveri E,Pascutto C,Lazzarino M,Cazzola M

更新日期：2006-11-01 00:00:00

abstract：:In the evaluation of cervical cancer, computed tomography (CT) is used primarily to stage advanced tumors and evaluate for recurrence. Because of reports that CT imaging lacks sensitivity and specificity in the detection of primary tumors and metastatic lesions, its use in these applications has been limited, but rece...

journal_title：Cancer

authors： Pannu HK,Fishman EK

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:The frequency of mutant p53 in bone marrow metastases of patients with carcinoma of the prostate (CaP) and in matched sets of metastatic and primary lesions from the same patients was investigated. The data were examined in relation to prior treatment with androgen ablation (AA) therapy and were compared wit...

journal_title：Cancer

authors： Meyers FJ,Gumerlock PH,Chi SG,Borchers H,Deitch AD,deVere White RW

更新日期：1998-12-15 00:00:00

abstract：:We report on an 89-year-old female admitted with signs of intestinal obstruction in whom three independent adenocarcinomas of the proximal jejunum were found. Multiple foci of pyloric gland metaplasia, glandular hyperplasia and dysplasia, carcinoma-in-situ, and several varieties of adenocarcinoma were identified on mi...

journal_title：Cancer

authors： Warner TF,Peralta J

更新日期：1979-09-01 00:00:00

abstract：:Although the conference could not provide a definitive etiologic explanation for the observed increase in incidence of human brain tumors, particularly among the elderly, nevertheless, this interdisciplinary gathering of prominent scientists and clinicians proved invaluable in identifying new avenues of research. Clea...

journal_title：Cancer

authors： Brem S,Rozental JM,Moskal JR

更新日期：1995-08-15 00:00:00

abstract：:A series of 108 prospectively collected human pancreata were evaluated histologically for the presence of acinar cell and ductal lesions. Foci of dysplastic acinar cells were present in 44% of the series. Some of the focal acinar cell abnormalities were similar to atypical acinar cell nodules which have been described...

journal_title：Cancer

authors： Longnecker DS,Shinozuka H,Dekker A

更新日期：1980-02-01 00:00:00

abstract：:Pancreatic carcinomas have been induced in Wistar and W/LEW rats by administration of total azaserine doses of 150-520 mg/kg by injection or oral routes over periods of 5-52 weeks. The latent period for development of invasive carcinomas was 1-2 years, but focal abnormalities in acinar cells appear earlier. The incide...

journal_title：Cancer

authors： Longnecker DS,Roebuck BD,Yager JD Jr,Lilja HS,Siegmund B

更新日期：1981-03-15 00:00:00

abstract：:Sixty patients with advanced prostatic carcinoma were treated with monthly subcutaneous injections of a depot formulation of goserelin, a luteinizing hormone-releasing hormone (LHRH) analogue (Zoladex, ICI Pharma, Destelbergen, Belgium). All patients were regularly evaluated with measurements of luteinizing hormone (L...

journal_title：Cancer

authors： Mahler C,Verhelst J,Chaban M,Denis L

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:The current study was conducted to expedite international standardized reporting of bone marrow disease in children with neuroblastoma and to improve equivalence of care. METHODS:A multidisciplinary International Neuroblastoma Response Criteria Bone Marrow Working Group was convened by the US National Cance...

journal_title：Cancer

authors： Burchill SA,Beiske K,Shimada H,Ambros PF,Seeger R,Tytgat GA,Brock PR,Haber M,Park JR,Berthold F

更新日期：2017-04-01 00:00:00

abstract：:Only three previous reports on the ultrastructural appearance of tibial adamantinoma have been found among some 120 cases of this tumor reported in the literature. The tumor in our case is less differentiated than the cases previously reported. We believe it is of epithelial character and the possibilities of its hist...

journal_title：Cancer

authors： Yoneyama T,Winter WG,Milsow L

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:Assessment of the responses of osteosarcoma patients to preoperative chemotherapy is of clinical importance. The purpose of this study was to estimate the accuracy of angiography and thallium-201 scintigraphy, compared with histology, in assessing the responses of patients with osteosarcoma to preoperative c...

journal_title：Cancer

authors： Kunisada T,Ozaki T,Kawai A,Sugihara S,Taguchi K,Inoue H

更新日期：1999-09-15 00:00:00

abstract：BACKGROUND:Renal medullary carcinoma is a rare tumor that is most common in young black men with sickle cell disease or trait. Patients often present with advanced disease at the time of diagnosis, and their prognosis is poor, even with aggressive therapy. The clinical and pathologic features of renal medullary carcino...

journal_title：Cancer

authors： Assad L,Resetkova E,Oliveira VL,Sun W,Stewart JM,Katz RL,Caraway NP

更新日期：2005-02-25 00:00:00

abstract：BACKGROUND:Parents of children with cancer have unmet information needs regarding future limitations resulting from cancer or its treatment. Prior research has demonstrated that, in early care discussions, clinicians focus on the acute effects of therapy rather than long-term limitations, partly due to worries of causi...

journal_title：Cancer

authors： Greenzang KA,Cronin AM,Kang TI,Mack JW

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Strumal carcinoids (SC) are ovarian tumors containing thyroid parenchyma admixed with carcinoid elements. Microscopically, the carcinoid component of SC usually presents a ribbon or trabecular pattern similar to the pattern exhibited by hindgut carcinoids. The authors designed an immunohistochemical study to...

journal_title：Cancer

authors： Sidhu J,Sánchez RL

更新日期：1993-09-01 00:00:00

abstract：:Twenty-three leukemic children were studied prospectively to detect chronic effects of therapy. All patients received CNS prophylaxis, including 2400 R cranial irradiation, and intermittent maintenance therapy with intravenous methotrexate, cyclophosphamide and cytosine arabinoside. Neurologic symptoms were observed i...

journal_title：Cancer

authors： McIntosh S,Klatskin EH,O'Brien RT,Aspnes GT,Kammerer BL,Snead C,Kalavsky SM,Pearson HA

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:Several histologic classifications of thymomas have been proposed, and attempts have been made to correlate the different histologic subtypes to clinical behavior and prognosis. Recently, Marino and Müller-Hermelink and Kirchner et al. proposed a new morphologic classification of thymomas based on the resemb...

journal_title：Cancer

authors： Quintanilla-Martinez L,Wilkins EW Jr,Choi N,Efird J,Hug E,Harris NL

更新日期：1994-07-15 00:00:00

abstract：:Oat-cell carcinoma of the thymus gland is exceedingly rare as a primary lesion, and only a few cases have been reported. We report a case in which a neoplasm interpreted as an oat-cell carcinoma was intimately associated with and arose in transition from a carcinoid tumor of the thymus. Ultrastructural features of thi...

journal_title：Cancer

authors： Wick MR,Scheithauer BW

更新日期：1982-04-15 00:00:00

abstract：BACKGROUND:The authors have noted that in cervical cytology specimens from perimenopausal and postmenopausal women, the diagnosis of atypical squamous cells of undetermined significance (ASC-US), as defined in the Bethesda system, is often not associated with a clinically evident lesion on follow-up. Reflex human papil...

journal_title：Cancer

authors： Johnston EI,Logani S

更新日期：2007-06-25 00:00:00

abstract：:A patient with metastatic islet cell carcinoma of the pancreas, recurrent peptic ulcer disease, and hypergastrinemia (Zollinger-Ellison syndrome) developed symptomatic hypercalcemia and renal insufficiency; she was treated with streptozotocin after parathyroidectomy failed to control her hypercalcemia. Shortly after s...

journal_title：Cancer

authors： Cryer PE,Hill GJ II

更新日期：1976-12-01 00:00:00

abstract：:Transgenic model systems provide tools for obtaining information that clarifies important relationships between genetic alterations and carcinogenesis. One such relationship is the induction of specific growth factor activities by dominantly acting oncogenes. Using a "transgenic organ" model referred to as mouse prost...

journal_title：Cancer

authors： Thompson TC,Truong LD,Timme TL,Kadmon D,McCune BK,Flanders KC,Scardino PT,Park SH

更新日期：1993-02-01 00:00:00