Delays in diagnosis and bladder cancer mortality.

abstract：BACKGROUND:The goal of the current study was to assess the toxicity, safety, and efficacy of pentostatin in patients with T-cell lymphoid malignancies. METHODS:Patients were eligible if they had biopsy-proven T-cell lymphoma or leukemia and failure to respond to previous therapy or an expected complete response rate t...

journal_title：Cancer

authors： Tsimberidou AM,Giles F,Duvic M,Fayad L,Kurzrock R

更新日期：2004-01-15 00:00:00

abstract：:There is now considerable interest in gastrointestinal stromal tumor (GIST) because it can be treated effectively with a targeted molecular agent. The majority of GISTs contain an activating mutation in the KIT protooncogene or, occasionally, in the platelet-derived growth factor-alpha (PDGFRA) gene. Five years ago, i...

journal_title：Cancer

authors： van der Zwan SM,DeMatteo RP

更新日期：2005-11-01 00:00:00

abstract：:The results of surgical treatment alone for 142 cases of carcinoma of the rectum and rectosigmoid from the Massachusetts General Hospital were reviewed. The incidence of local failure as any component of failure was found to be strongly dependent on the pathologic stage, and for Dukes' A was 8.0% (3/39); Dukes' B, 31%...

journal_title：Cancer

authors： Rich T,Gunderson LL,Lew R,Galdibini JJ,Cohen AM,Donaldson G

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:Obesity has been associated with inferior outcomes in operable breast cancer, but the relation between body mass index (BMI) and outcomes by breast cancer subtype has not been previously evaluated. METHODS:The authors evaluated the relation between BMI and outcomes in 3 adjuvant trials coordinated by the Ea...

journal_title：Cancer

authors： Sparano JA,Wang M,Zhao F,Stearns V,Martino S,Ligibel JA,Perez EA,Saphner T,Wolff AC,Sledge GW Jr,Wood WC,Fetting J,Davidson NE

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Seminal vesicle (SV) invasion at the time of radical prostatectomy (RP) generally is considered to be indicative of poor outcome. The authors examined whether there was a subset of men with SV invasion who had long-term prostate-specific antigen (PSA) progression-free survival. METHODS:Data were examined fr...

journal_title：Cancer

authors： Freedland SJ,Aronson WJ,Presti JC Jr,Amling CL,Terris MK,Trock B,Kane CJ

更新日期：2004-04-15 00:00:00

abstract：BACKGROUND:Standard therapy for advanced head and neck carcinoma is surgery and radiation, and the subsequent 5-year survival with this treatment has been less than 50%. New combined modality treatment strategies are being tested to improve survival. New chemotherapy combinations are being developed and administered si...

journal_title：Cancer

authors： Dunphy FR,Boyd JH,Kim HJ,Dunphy CH,Harrison BR,Dunleavy TL,Rodriguez JJ,McDonough EM,Minster JR,Hilton JG

更新日期：1997-05-15 00:00:00

abstract：:A series of 108 prospectively collected human pancreata were evaluated histologically for the presence of acinar cell and ductal lesions. Foci of dysplastic acinar cells were present in 44% of the series. Some of the focal acinar cell abnormalities were similar to atypical acinar cell nodules which have been described...

journal_title：Cancer

authors： Longnecker DS,Shinozuka H,Dekker A

更新日期：1980-02-01 00:00:00

abstract：:Trastuzumab is a monoclonal antibody used for the treatment of metastatic breast carcinoma in women whose tumors overexpress the HER2 protein. Cardiotoxicity has been reported to occur with trastuzumab when administered alone and in combination with antineoplastic agents, particularly anthracyclines. The risk of cardi...

journal_title：Cancer

authors： Keefe DL

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Widespread disparities in care have been documented in women with gynecologic cancer in the United States. This study was designed to determine whether structural barriers to optimal care were present during the preoperative period for patients with gynecologic cancer. METHODS:A retrospective review was con...

journal_title：Cancer

authors： Frey MK,Moss HA,Musa F,Rolnitzky L,David-West G,Chern JY,Boyd LR,Curtin JP

更新日期：2016-03-15 00:00:00

abstract：:Primary splenic angiosarcomas are rare neoplasms. The diagnosis can only be made at surgery. Splenectomy prior to rupture prolongs survival. An unusual case report is presented and the literature reviewed. ...

journal_title：Cancer

authors： Smith VC,Eisenberg BL,McDonald EC

更新日期：1985-04-01 00:00:00

abstract：:A bronchogenic tumor was removed from a 12-year-old girl. Histology showed a clear cell lesion with electron microscope features compatible with serous acinic cell origin. ...

journal_title：Cancer

authors： Katz DR,Bubis JJ

更新日期：1976-08-01 00:00:00

abstract：:Records of 100 consecutive hospitalized cancer patients referred for psychiatric consultation were reviewed. These patients constituted only 5% of those seen by the Psychiatry Consultation Service during the study period. Fifty-six percent of the referred patients were diagnosed as depressed and 40% as having organic ...

journal_title：Cancer

authors： Levine PM,Silberfarb PM,Lipowski ZJ

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:We sought to determine the impact of radical nephrectomy case volume, hospital size, and geographic region on immediate surgical outcomes for patients undergoing radical nephrectomy in academic centers across the country. METHODS:The University HealthSystem Consortium (UHC) Clinical Data Base was queried fo...

journal_title：Cancer

authors： Mitchell RE,Lee BT,Cookson MS,Barocas DA,Duke Herrell S,Clark PE,Smith JA,Chang SS

更新日期：2009-06-01 00:00:00

abstract：:In recent years, an increased understanding of T-cell-regulatory mechanisms has led to the development of a novel class of immune-checkpoint inhibitors that have robust clinical activity against a broad array of malignancies-even those that historically were not believed to be sensitive to immune therapy. With this, t...

journal_title：Cancer

authors： Salama AK,Postow MA,Salama JK

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Heavy alcohol consumption, viral hepatitis, and diabetes are risk factors for hepatocellular carcinoma (HCC). However, to the authors' knowledge, the information concerning their interaction effect in patients with risk of HCC is sparse. METHODS:A population-based, case-control study of HCC was conducted du...

journal_title：Cancer

authors： Yuan JM,Govindarajan S,Arakawa K,Yu MC

更新日期：2004-09-01 00:00:00

abstract：:Unexpected nephrotoxicity has been described in high-dose, bolus ifosfamide (IFF) therapy. Renal injury is not thought to occur in patients receiving fractionated schedules, although microscopic hematuria from bladder irritation is not uncommon. IFF is undergoing trials in patients with malignant lymphomas, gynecologi...

journal_title：Cancer

authors： Patterson WP,Khojasteh A

更新日期：1989-02-15 00:00:00

abstract：:The authors measured the serial serum carcinoembryonic antigen (CEA) levels in patients with recurrent gastric or colorectal carcinoma. Among the 45 patients with recurrent gastric carcinomas, those with lung metastases showed the most prolonged CEA doubling time (CEA-DT), followed by those with liver and peritoneal m...

journal_title：Cancer

authors： Umehara Y,Kimura T,Yoshida M,Oba N,Harada Y

更新日期：1993-06-15 00:00:00

abstract：BACKGROUND:The authors hypothesized that insurance payer and race would influence the care and outcomes for patients with breast carcinoma. METHODS:The authors examined treatments and adjusted risk of death (through 1997) for all incident cases of breast carcinoma occurring in Florida in 1994 (n = 11,113) by using sta...

journal_title：Cancer

authors： Roetzheim RG,Gonzalez EC,Ferrante JM,Pal N,Van Durme DJ,Krischer JP

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Circulating immune complexes (CIC) have been implicated as a cause of malignancy-associated immunosuppression and disease progression. Previous attempts to remove CIC by pheresis or immunoadsorption over a Staphylococcus aureus protein A column have resulted in a few clinical responses, however the relations...

journal_title：Cancer

authors： Fennelly DW,Norton L,Sznol M,Hakes TB

更新日期：1995-04-15 00:00:00

abstract：BACKGROUND:The optimal imaging for the staging of oropharyngeal cancer is not well defined. METHODS:The linked Surveillance, Epidemiology, and End Results (SEER)-Medicare database for 2006 through 2011 was used to compare patient characteristics and hospital region by the initial imaging modality used for patients wit...

journal_title：Cancer

authors： Morgan RL,Eguchi MM,Mueller AC,Daugherty SL,Amini A,Karam SD

更新日期：2019-08-15 00:00:00

abstract：:A new approach using anthropometric, radiographic, biochemical, and ultrasonic methods allowed partition of body weight into fat, fat-free mass, skeletal muscle, and volume of heart, liver, kidneys, spleen, and tumor. These methods were used to evaluate body composition longitudinally in a pilot group of nine cancer p...

journal_title：Cancer

authors： Heymsfield SB,McManus CB

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:The goal of this study was to examine the clinical significance of ZNF217 amplification and assess whether ZNF217 could be a potential therapeutic target in ovarian clear cell carcinoma (OCCC). METHODS:ZNF217 expression and amplification in OCCC was assessed by immunohistochemistry, fluorescence in situ hyb...

journal_title：Cancer

authors： Rahman MT,Nakayama K,Rahman M,Nakayama N,Ishikawa M,Katagiri A,Iida K,Nakayama S,Otsuki Y,Shih IeM,Miyazaki K

更新日期：2012-06-01 00:00:00

abstract：:The metabolism of 5-fluorouracil (5-FU) was studied in biopsy specimens of primary colorectal cancer and healthy colonic mucosa obtained from previously untreated patients immediately after surgical removal. The conversion of 5-FU to anabolites was measured under saturating substrate (5-FU) and cosubstrate concentrati...

journal_title：Cancer

authors： Peters GJ,van Groeningen CJ,Laurensse EJ,Pinedo HM

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Prevalence usually is defined as the proportion of individuals alive who previously had a diagnosis of the disease, regardless of whether the individuals still are receiving treatment or are cured. The objective of this study was to estimate the proportion of elderly patients with colorectal carcinoma (CRC) ...

journal_title：Cancer

authors： Mariotto A,Warren JL,Knopf KB,Feuer EJ

更新日期：2003-09-15 00:00:00

abstract：:Seven patients with advanced locoregional or metastatic squamous cell carcinoma of the skin were treated with cis-daimminedichloroplatin (cisplatin) and 5-fluorouracil (5-FU). Responses were seen in six of seven patients (three partial responses [PR] and three complete responses [CR]). One patient is alive and disease...

journal_title：Cancer

authors： Khansur T,Kennedy A

更新日期：1991-04-15 00:00:00

abstract：:Between July 1951 and January 1984, 14 female patients (11 black and three white; average age, 58 years) were treated for primary urethral carcinoma. Five patients had radical surgery, six received preoperative radiotherapy (2000 cGy in five fractions) followed by anterior exenteration, and three had definitive radiot...

journal_title：Cancer

authors： Moinuddin Ali M,Klein FA,Hazra TA

更新日期：1988-07-01 00:00:00

abstract：BACKGROUND:Aggressive treatment of early stage prostate carcinoma (PC) is limited primarily to two modalities: radical prostatectomy (RP) and external beam radiation therapy (RT). The authors conducted a population-based study of Detroit area men with localized PC to determine the outcome of bowel, urinary, and sexual ...

journal_title：Cancer

authors： Schwartz K,Bunner S,Bearer R,Severson RK

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:The objective of this study was to create a nomogram model integrating clinical and multiparametric magnetic resonance imaging (MP-MRI)-based variables to predict prostate cancer upgrading in a population of active surveillance (AS) patients. METHODS:Prostate cancer patients on AS who underwent MP-MRI with ...

journal_title：Cancer

authors： Lai WS,Gordetsky JB,Thomas JV,Nix JW,Rais-Bahrami S

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Estrogen receptor-alpha (ERalpha) is variably expressed in hepatocellular carcinoma (HCC) and is believed to be correlated with prognosis and survival. Recently, another estrogen receptor (ERbeta) has been identified, but its relevance in liver diseases is unknown. METHODS:The expression of ERbeta in the li...

journal_title：Cancer

authors： Iavarone M,Lampertico P,Seletti C,Francesca Donato M,Ronchi G,del Ninno E,Colombo M

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Humoral hypercalcemia rarely is associated with colorectal carcinoma; to the authors' knowledge only nine cases have been reported to date. METHODS:Two cases of advanced colorectal carcinoma with humoral hypercalcemia of malignancy (HHM) are presented. RESULTS:The two patients had severe hypercalcemia with...

journal_title：Cancer

authors： Lortholary AH,Cadeau SD,Bertrand GM,Guerin-Meyer VI,Gamelin EC,Audran MJ

更新日期：1999-12-01 00:00:00