Synergism of alcohol, diabetes, and viral hepatitis on the risk of hepatocellular carcinoma in blacks and whites in the U.S.

abstract：:Histiocytic medullary reticulosis (HMR) was originally defined as a neoplastic disorder. Some cases reported as HMR have been characterized by a systemic proliferation of mature histiocytes showing hemophagocytosis, bone marrow necrosis, pancytopenia, hepatitis, and coagulopathy. Clinically, these patients have fever ...

journal_title：Cancer

authors： Risdall RJ,Brunning RD,Hernandez JI,Gordon DH

更新日期：1984-12-15 00:00:00

abstract：:A retrospective study of 702 patients with clinically positive nodes associated with squamous cell carcinoma of the oral cavity, supraglottic larynx, and hypopharynx observed from 1954 to 1968 was done. The policies of treatment for the neck were not standardized during those years. Three hundred eleven patients who s...

journal_title：Cancer

authors： Jesse RH,Fletcher GH

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:The measurement of estrogen receptors (ER) in breast cancer specimens has traditionally been assessed with a dextran-coated charcoal assay (DCCA). More recently the immunohistochemical staining (IHC) method has gained increasing popularity because of its ability to use fixed tissue, assess needle biopsies, a...

journal_title：Cancer

authors： Alberts SR,Ingle JN,Roche PR,Cha SS,Wold LE,Farr GH Jr,Krook JE,Wieand HS

更新日期：1996-08-15 00:00:00

abstract：:Transcriptional dysregulation induced by disease-defining genetic alterations of proteins in transcriptional machinery is a key feature of cancers. Mediator complex subunit 12 (MED12) is the central architectural subunit in the kinase module of Mediator, a large transcriptional regulatory complex that controls essenti...

journal_title：Cancer

authors： Zhang S,O'Regan R,Xu W

更新日期：2020-03-01 00:00:00

abstract：:Numerous examples exist of prognostic factors that have been conclusively established and that can segregate the target patient population into subgroups with vastly different outcomes. At the same time, we can expect, in the majority of trials being conducted, that if a new treatment turns out to be successful, it ge...

journal_title：Cancer

authors： Sather HN

更新日期：1986-07-15 00:00:00

abstract：:The incidence of breast cancer rose about 1% per year between 1940 and 1980 according to data in the Connecticut Tumor Registry. A sharp increase of 32% was reported between 1980 and 1987 in the Surveillance, Epidemiology and End Results Program of the National Cancer Institute. Data from this program shows that the i...

journal_title：Cancer

authors： Garfinkel L,Boring CC,Heath CW Jr

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:Approximately 5% of clear cell renal cell carcinomas contain components with sarcomatoid differentiation. It has been suggested that the sarcomatoid elements arise from the clear cell tumors as a consequence of clonal expansions of neoplastic cells with progressively more genetic alterations. Analysis of the...

journal_title：Cancer

authors： Jones TD,Eble JN,Wang M,Maclennan GT,Jain S,Cheng L

更新日期：2005-09-15 00:00:00

abstract：BACKGROUND:If some adenomas do not bleed over several years, they will cause systematic false-negative fecal immunochemical test (FIT) results. The long-term effectiveness of FIT screening has been estimated without accounting for such systematic false-negativity. There are now data with which to evaluate this issue. ...

journal_title：Cancer

authors： van der Meulen MP,Lansdorp-Vogelaar I,van Heijningen EM,Kuipers EJ,van Ballegooijen M

更新日期：2016-06-01 00:00:00

abstract：:Wolfe has suggested that the mammographic parenchymal patterns can be used to identify a group with high incidence of breast cancer. To evaluate this claim, mammograms of women with breast cancer that was detected at the University of Michigan Breast Cancer Detection Demonstration Project have been classified and comp...

journal_title：Cancer

authors： Threatt B,Norbeck JM,Ullman NS,Kummer R,Roselle P

更新日期：1980-05-15 00:00:00

abstract：BACKGROUND:Severe fatigue is a common and distressing symptom affecting approximately one in four survivors of breast cancer. The current study examined the efficacy of Internet-based cognitive behavioral therapy (ICBT) for severe fatigue in survivors of breast cancer compared with care as usual (CAU). METHODS:The aut...

journal_title：Cancer

authors： Abrahams HJG,Gielissen MFM,Donders RRT,Goedendorp MM,van der Wouw AJ,Verhagen CAHHVM,Knoop H

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Chronic myeloid leukemia (CML) can be treated effectively with tyrosine kinase inhibitor therapy directed at BCR-ABL, but access to care, medication cost, and adherence may be barriers to treatment. This study was designed to determine whether the insurance status at diagnosis influences CML patient outcomes...

journal_title：Cancer

authors： Perry AM,Brunner AM,Zou T,McGregor KL,Amrein PC,Hobbs GS,Ballen KK,Neuberg DS,Fathi AT

更新日期：2017-07-01 00:00:00

abstract：:Between January 1, 1980, and July 31, 1985, 168 patients were treated at our institution for chronic lymphocytic leukemia (CLL). Splenectomy was performed on 32 (23 men and 9 women). The mean age of these surgical patients was 59.4 years (range, 43-75). Twenty-four patients had received chemotherapy and/or corticother...

journal_title：Cancer

authors： Delpero JR,Gastaut JA,Letreut YP,Caamano A,Mathieu-Tubiana N,Maraninchi D,Simon-Lejeune C,Mascret B,Blanc AP,Sebahoun G

更新日期：1987-01-15 00:00:00

abstract：:A new method of arterially administering an oily anticancer agent was successfully established for the selective targeting of metastatic lymph nodes. A high molecular weight anticancer agent, a conjugate of copolymer (styrene maleic acid) to neocarzinostatin (SMANCS) was prepared in our laboratory and dissolved in a l...

journal_title：Cancer

authors： Ohtsuka N,Konno T,Miyauchi Y,Maeda H

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:The prognostic relevance of activated oncogenes and oncoproteins has not been well studied in papillary thyroid cancer, which is slow-growing, with only regional spread in most cases. Therefore, the influence of some protein markers and tumor cell proliferation on disease progress in a series of patients wit...

journal_title：Cancer

authors： Akslen LA,Varhaug JE

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Because of morphologic similarities, the differential diagnosis of granulocytic sarcoma (GS) in fine-needle aspiration (FNA) specimens includes non-Hodgkin or Hodgkin lymphoma, extramedullary hematopoiesis, poorly differentiated carcinoma, and infection. METHODS:Twenty-six FNAs and 1 pleural effusion fluid ...

journal_title：Cancer

authors： Suh YK,Shin HJ

更新日期：2000-12-25 00:00:00

abstract：BACKGROUND:Epstein-Barr virus (EBV) infection has been implicated in the pathogenesis of certain subtypes of salivary gland tumors in the adult population. However, to the authors' knowledge its role in pediatric salivary gland tumors, a rare disease, has not been explored previously. METHODS:Thirteen cases of primary...

journal_title：Cancer

authors： Venkateswaran L,Gan YJ,Sixbey JW,Santana VM

更新日期：2000-07-15 00:00:00

abstract：:The difficulties encountered in establishing a diagnosis of a malignant peritoneal mesothelioma are emphasized in a patient who developed the lesion 16 years after radiation therapy for a seminoma of the testis. Historically, histologically, electron microscopically, and by microincineration, there was no evidence of ...

journal_title：Cancer

authors： Stock RJ,Fu YS,Carter JR

更新日期：1979-09-01 00:00:00

abstract：BACKGROUND:Hepatic artery administration of iodine-131-Lipiodol serves as a modality that delivers targeted radiation therapy to hepatocellular carcinoma. Its efficacy has been promising according to trials conducted in the adjuvant setting after hepatic resection. Further investigation of its role in the palliative se...

journal_title：Cancer

authors： Chua TC,Chu F,Butler SP,Quinn RJ,Glenn D,Liauw W,Morris DL

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Alpha-interferon and dexamethasone are each effective in patients with multiple myeloma and have a combined inhibitory effect on the in vitro growth of myeloma colonies. The effect of combined therapy in newly diagnosed patients is unknown. METHODS:Fifty-one consecutive patients with previously untreated mu...

journal_title：Cancer

authors： Dimopoulos MA,Weber D,Delasalle KB,Alexanian R

更新日期：1993-11-01 00:00:00

abstract：:Advances in clinical medicine require effective translational research. Ideally, this research will be performed by multidisciplinary teams that include both physicians and basic scientists. However, the current system does not appropriately train either physicians or basic scientists for these careers. In addition, t...

journal_title：Cancer

authors： Pickering CR,Bast RC Jr,Keyomarsi K

更新日期：2015-03-15 00:00:00

abstract：BACKGROUND:In recent years numerous reports have discussed the relationship between the human leukocyte antigen and lung cancer. However, the genetic background of lung cancer has not yet been precisely clarified. METHODS:To investigate the genetic background of lung cancer, the human leukocyte antigens in 159 normal ...

journal_title：Cancer

authors： Shimura T,Hagihara M,Takebe K,Munkhbat B,Odaka T,Kato H,Nagamachi Y,Tsuji K

更新日期：1994-02-15 00:00:00

abstract：BACKGROUND:The 5-year survival rate of patients with submucosal (sm) esophageal carcinoma continues to be much worse than that with intramucosal (m) lesions. The reasons are unclear, but matrix metalloproteinases (MMPs) and membrane type matrix metalloproteinases (MT-MMPs) are known to be involved in degradation of ext...

journal_title：Cancer

authors： Ohashi K,Nemoto T,Nakamura K,Nemori R

更新日期：2000-05-15 00:00:00

abstract：BACKGROUND:High rates of locoregional recurrence have been reported from surgical series of locally advanced melanoma. In this study, the outcomes of patients treated with surgery and postoperative hypofractionated radiation therapy were reviewed to assess local recurrence and survival. METHODS:From 1989 to 1998, 174 ...

journal_title：Cancer

authors： Stevens G,Thompson JF,Firth I,O'Brien CJ,McCarthy WH,Quinn MJ

更新日期：2000-01-01 00:00:00

abstract：:In 79 cases of histologically verified anaplastic giant-cell carcinoma, symptoms, treatment, and prognosis were documented. Seventy-eight patients are dead, the mean survival time being 2.5 months. One patient is cured. It was concluded that surgery and/or radiotherapy alone are not sufficient. The results from an add...

journal_title：Cancer

authors： Jereb B,Stjernswärd J,Löwhagen T

更新日期：1975-05-01 00:00:00

abstract：:Long-term vocational achievements of 40 survivors of cancer diagnosed during adolescence were examined and compared with 40 healthy sex-matched and age-matched controls. Patients' ages at diagnosis ranged from 13 to 19 years (mean, 16.15). Study subjects had survived cancer for over 5 years and were on no cancer thera...

journal_title：Cancer

authors： Tebbi CK,Bromberg C,Piedmonte M

更新日期：1989-01-01 00:00:00

abstract：:Three children with ALL having poor prognostic features developed clinical and laboratory evidence of disseminated intravascular coagulation (DIC). Two developed a bleeding diathesis associated temporally with a rapid drop in blast cell counts during induction therapy with L-asparaginase, prednisone, and vincristine. ...

journal_title：Cancer

authors： Champion LA,Luddy RE,Schwartz AD

更新日期：1978-04-01 00:00:00

abstract：BACKGROUND:Tobacco smoking, alcohol abuse, and high-risk human papillomavirus (HPV) are risk factors in the etiology of oropharyngeal squamous cell carcinomas (SCCs). The TP53 polymorphism, in which an arginine (R) is changed to proline (P) at codon 72, is functionally significant and could therefore be a predisposing ...

journal_title：Cancer

authors： Perrone F,Mariani L,Pastore E,Orsenigo M,Suardi S,Marcomini B,DaRiva L,Licitra L,Carbone A,Pierotti MA,Pilotti S

更新日期：2007-06-15 00:00:00

abstract：:From 1974 to 1983, simple and radical nephrectomies were performed at the Chaim Sheba Medical Center (Tel Hashomer, Israel) for renal cell carcinoma. The authors reviewed 109 cases that were followed for a period ranging from 5 to 14 years. Simple nephrectomy was performed in 55 patients, and 54 patients underwent rad...

journal_title：Cancer

authors： Ramon J,Goldwasser B,Raviv G,Jonas P,Many M

更新日期：1991-05-15 00:00:00

abstract：BACKGROUND:Occult hepatitis B virus (HBV) infection frequently occurs in patients with HBV surface antigen (HBsAg)-negative chronic liver disease, and much evidence suggests that it is a risk factor for hepatocellular carcinoma (HCC) development. However, to the authors' knowledge, no follow-up study has been performed...

journal_title：Cancer

authors： Squadrito G,Pollicino T,Cacciola I,Caccamo G,Villari D,La Masa T,Restuccia T,Cucinotta E,Scisca C,Magazzu D,Raimondo G

更新日期：2006-03-15 00:00:00

abstract：:We present a case with the unusual association of Graves' disease and functioning pulmonary metastases of follicular thyroid carcinoma. Unlike other reports of thyroid cancer and thyrotoxicosis, this patient's hyperthyroidism was related to a hyperfunctioning primary thyroid neoplasm and not merely to large amounts of...

journal_title：Cancer

authors： Grayzel EF,Bennett B

更新日期：1979-05-01 00:00:00