Changing trends. An overview of breast cancer incidence and mortality.


:The incidence of breast cancer rose about 1% per year between 1940 and 1980 according to data in the Connecticut Tumor Registry. A sharp increase of 32% was reported between 1980 and 1987 in the Surveillance, Epidemiology and End Results Program of the National Cancer Institute. Data from this program shows that the increase in incidence was due to localized cases and cancers of less than 2 cm in greatest dimension. In addition, a sharp increase in carcinoma in situ was observed. The increase in breast cancer incidence coincides with an increased use of mammography in asymptomatic women in the 1980s. Mortality from breast cancer has changed little since the 1930s, but the increases in localized and small-size tumors and decreases in the rate of tumors of 3 cm or larger at diagnosis indicates that breast cancer mortality may start to decrease. Evidence from provisional breast cancer monthly mortality data suggests that there was a 3-6% drop in 1991 compared to 1990.






Garfinkel L,Boring CC,Heath CW Jr




Has Abstract


1994-07-01 00:00:00




1 Suppl










  • The role of clinicians in determining radioactive iodine use for low-risk thyroid cancer.

    abstract:BACKGROUND:There is controversy regarding the optimal management of thyroid cancer. The proportion of patients with low-risk thyroid cancer who received radioactive iodine (RAI) treatment increased over the last 20 years, and little is known about the role played by clinicians in hospital-level RAI use for low-risk dis...


    pub_type: 杂志文章


    authors: Haymart MR,Banerjee M,Yang D,Stewart AK,Koenig RJ,Griggs JJ

    更新日期:2013-01-15 00:00:00

  • Nerve sheath myxoma of digital nerve.

    abstract::A case of a dermal nerve sheath myxoma arising in a digital nerve is reported. Similar tumors and its variants have been termed neurothekeoma, pacinian neurofibroma, bizarre cutaneous neurofibroma, and plexiform neurofibroma. The perineural sheath or the Schwann cell have been presumed to be the cell of origin by seve...


    pub_type: 杂志文章,评审


    authors: Blumberg AK,Kay S,Adelaar RS

    更新日期:1989-03-15 00:00:00

  • Carcinoma of the pancreas: review of MGH experience from 1963 to 1973. Analysis of surgical failure and implications for radiation therapy.

    abstract::A retrospective study was done of all patients who were seen for definitive treatment of adenocarcinoma of the pancreas at the Massachusetts General Hospital from 1963 to 1973. There were a total of 145 patients. Thirty-one patients were treated with radical surgery, with a 16% operative mortality, a 5-year crude surv...


    pub_type: 杂志文章


    authors: Tepper J,Nardi G,Sutt H

    更新日期:1976-03-01 00:00:00

  • Neonatal alveolar rhabdomyosarcoma with skin and brain metastases.

    abstract:BACKGROUND:Approximately 5-10% of patients with rhabdomyosarcomas (RMS) are diagnosed during the first year of life, and their clinical characteristics have been well documented. However, because RMS rarely occurs during the neonatal period, little is known about neonatal RMS. METHODS:Four patients with neonatal RMS w...


    pub_type: 杂志文章


    authors: Rodriguez-Galindo C,Hill DA,Onyekwere O,Pin N,Rao BN,Hoffer FA,Kun LE,Pappo AS,Santana VM

    更新日期:2001-09-15 00:00:00

  • Barriers and incentives for primary care physicians in cancer prevention and detection.

    abstract::The American Cancer Society estimates that nearly a million new cases of cancer will occur and that approximately a half million lives will be lost in 1987. These figures may double by the year 2000 primarily because of our aging population, with age being the leading risk factor for cancer. It is believed that the ma...


    pub_type: 杂志文章


    authors: Williams PA,Williams M

    更新日期:1988-06-01 00:00:00

  • Associations between smoking status and stage of colorectal cancer at diagnosis in Massachusetts between 1982 and 1987.

    abstract::To examine the relationship between smoking and stage of colorectal cancer at diagnosis, data on 2788 current smokers and 6313 nonsmokers with known stage at diagnosis were obtained from the Massachusetts Cancer Registry. The stage at diagnosis was treated as a polytomous response variable in a logit-type, log-linear ...


    pub_type: 杂志文章


    authors: Longnecker MP,Clapp RW,Sheahan K

    更新日期:1989-09-15 00:00:00

  • The relationship between shaved margin and inked margin status in breast excision specimens.

    abstract:BACKGROUND:The presence of tumor at the inked margins (IMs) of breast specimens is associated with an increased risk of local recurrence after breast-conserving therapy for invasive breast carcinoma and ductal carcinoma in situ (DCIS). Given the importance of margin status, some have advocated the use of shaved margins...


    pub_type: 杂志文章


    authors: Guidi AJ,Connolly JL,Harris JR,Schnitt SJ

    更新日期:1997-04-15 00:00:00

  • Possible effects of non-HLA antibodies in common typing sera on HLA antigen frequency data in leukemia.

    abstract::Selective adsorption of several common "monospecific" HLA typing sera with HLA typed platelets, purified B lymphocytes, cultured lymphoid cells, or lymphocytes from patients with active chronic lymphocytic leukemia demonstrated that many of these sera contain antibodies to non-HLA antigens. Antibodies were detected to...


    pub_type: 杂志文章


    authors: Pollack MS,DuBois D

    更新日期:1977-06-01 00:00:00

  • Classic kaposi sarcoma: epidemiology and risk factors.

    abstract:BACKGROUND:Although Kaposi sarcoma (KS) initially was described over a century ago, its biology remains enigmatic and conflicting. Whereas the classic type occurs mainly in older men of Mediterranean or Eastern European backgrounds and is not linked to impairment of the host immune response, iatrogenic and human immuno...


    pub_type: 杂志文章,评审


    authors: Iscovich J,Boffetta P,Franceschi S,Azizi E,Sarid R

    更新日期:2000-02-01 00:00:00

  • Low cancer incidence and mortality in Utah.

    abstract::Utah cancer mortality for the years 1950-1969 and morbidity for the years 1966-1970 are reported. Utah had 18% fewer cases of cancer than expected based on the Third National Cancer Survey, and 24% fewer cancer deaths than expected based on national mortality data. Cancer sites associated with cigarette smoking and al...


    pub_type: 杂志文章


    authors: Lyon JL,Gardner JW,Klauber MR,Smart CR

    更新日期:1977-06-01 00:00:00

  • Chemotherapy for adenocystic carcinoma.

    abstract::Seventeen patients with adenocystic carcinoma have received 34 adequate trials of chemotherapy at Princess Margaret Hospital since 1969. There have been five objective responses to chemotherapy in 4 cases, lasting from five to 24 months, and 3 other patients have had stabilized disease for a period of five to seven mo...


    pub_type: 杂志文章


    authors: Tannock IF,Sutherland DJ

    更新日期:1980-08-01 00:00:00

  • Mucin core protein expression in extrahepatic bile duct carcinoma is associated with metastases to the liver and poor prognosis.

    abstract:BACKGROUND:Curative resection does not guarantee long term survival for the patient with extrahepatic bile duct carcinoma because of the possibility of metastases to the liver (LM). Expression of mucin core protein-1 (MUC1), sialyl-Le(x), and sialosyl-Tn in bile duct carcinoma was determined and compared with LM and pr...


    pub_type: 杂志文章


    authors: Takao S,Uchikura K,Yonezawa S,Shinchi H,Aikou T

    更新日期:1999-11-15 00:00:00

  • Marjolin's ulcer. The LSU experience.

    abstract::Skin cancers originating in areas of chronic injury (Marjolin's ulcers) are thought to behave in a more aggressive fashion than those due to other causes. The initial surgical treatment, especially the management of the regional lymph nodes, remains controversial. This review of 37 patients with Marjolin's ulcer evalu...


    pub_type: 杂志文章


    authors: Barr LH,Menard JW

    更新日期:1983-07-01 00:00:00

  • Receipt of cancer screening procedures among Hispanic and non-Hispanic health maintenance organization members.

    abstract:BACKGROUND:Hispanic Americans have been shown to receive fewer cancer screening procedures than nonminority populations. Although lack of insurance or a regular source of care appear to be important determinants, cultural factors also have been suggested. This study examines whether Hispanic patients receive cancer scr...


    pub_type: 杂志文章


    authors: Jacobs EA,Lauderdale DS

    更新日期:2001-01-01 00:00:00

  • A novel hypothesis on the sensitivity of the fecal occult blood test: Results of a joint analysis of 3 randomized controlled trials.

    abstract:BACKGROUND:Estimates of the fecal occult blood test (FOBT) (Hemoccult II) sensitivity differed widely between screening trials and led to divergent conclusions on the effects of FOBT screening. We used microsimulation modeling to estimate a preclinical colorectal cancer (CRC) duration and sensitivity for unrehydrated F...


    pub_type: 杂志文章


    authors: Lansdorp-Vogelaar I,van Ballegooijen M,Boer R,Zauber A,Habbema JD

    更新日期:2009-06-01 00:00:00

  • Overexpression of p53 and prognosis in breast cancer.

    abstract:BACKGROUND:Assessment of prognostic markers in breast cancer independent of the axillary lymph node status is of major concern for the application of adjuvant treatment regimens. The current treatment decision is based mainly on the axillary lymph node status. Because of improved screening methods, the number and propo...


    pub_type: 杂志文章


    authors: Friedrichs K,Gluba S,Eidtmann H,Jonat W

    更新日期:1993-12-15 00:00:00

  • Number of metastatic sites is a strong predictor of survival in patients with nonsmall cell lung cancer with or without brain metastases.

    abstract:BACKGROUND:The staging system for non-small cell lung cancer (NSCLC) does not consider tumor burden or number of metastatic sites, although oligometastases are more favorable. METHODS:Using log-rank testing, the authors analyzed overall survival (OS) in 1284 patients newly presenting with metastatic NSCLC by number of...


    pub_type: 杂志文章


    authors: Oh Y,Taylor S,Bekele BN,Debnam JM,Allen PK,Suki D,Sawaya R,Komaki R,Stewart DJ,Karp DD

    更新日期:2009-07-01 00:00:00

  • Endoscopic ultrasound-guided fine-needle aspiration biopsy of the adrenal glands: analysis of 24 patients.

    abstract:BACKGROUND:Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) biopsy allows the detailed imaging and FNA not only of both intramural and extramural structures and lesions of the gastrointestinal (GI) tract but also of various intraabdominal organs. Thus, EUS-FNA biopsy offers a novel opportunity to evaluate ...


    pub_type: 杂志文章


    authors: Jhala NC,Jhala D,Eloubeidi MA,Chhieng DC,Crowe DR,Roberson J,Eltoum I

    更新日期:2004-10-25 00:00:00

  • Chemotherapy-induced peripheral neuropathy: Identifying the research gaps and associated changes to clinical trial design.

    abstract:BACKGROUND:To the authors' knowledge, the empiric identification of agents and interventions to mitigate chemotherapy-induced peripheral neuropathy (CIPN) has resulted in only 1 agent that modestly mitigates it and no agents or interventions that prevent its development. This speaks to the need for a mechanistic unders...


    pub_type: 杂志文章


    authors: St Germain DC,O'Mara AM,Robinson JL,Torres AD,Minasian LM

    更新日期:2020-10-15 00:00:00

  • Dietary carcinogens and mammary carcinogenesis. Induction of rat mammary carcinomas by administration of heterocyclic amines in cooked foods.

    abstract::Grilled or fried meat and fish contain various mutagenic heterocyclic amines, and structures of at least 19 compounds have already been determined. Among these, 10 have been examined for long term carcinogenicity, all proving to be positive. 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), for example, preferen...


    pub_type: 杂志文章


    authors: Nagao M,Ushijima T,Wakabayashi K,Ochiai M,Kushida H,Sugimura T,Hasegawa R,Shirai T,Ito N

    更新日期:1994-08-01 00:00:00

  • Comparison of continuously infused 5-fluorouracil with bolus injection in treatment of patients with colorectal adenocarcinoma.

    abstract::In a randomized series of 70 patients with with colo rectal adenocarcinoma, a comparison of systemic 5-fluorouracil chemotherapy administered as a continuous 120-hours infusion vs. intravenous bolus injection daily for 5 days demonstrated superiority of prolonged intravenous infusion. The most striking advantage of pr...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Seifert P,Baker LH,Reed ML,Vaitkevicius VK

    更新日期:1975-07-01 00:00:00

  • Expression of autocrine motility factor receptor in colorectal cancer as a predictor for disease recurrence.

    abstract:BACKGROUND:New biologic prognostic factors are needed to guide the treatment of patients with colorectal cancer. The prognostic value of the altered expression of the cell surface glycoprotein gp78, which has been implicated in tumor-cell invasion and metastasis as an autocrine motility factor (AMF) receptor, was evalu...


    pub_type: 杂志文章


    authors: Nakamori S,Watanabe H,Kameyama M,Imaoka S,Furukawa H,Ishikawa O,Sasaki Y,Kabuto T,Raz A

    更新日期:1994-10-01 00:00:00

  • A renal cell carcinoma neoplastic antigen detectable by immunohistochemistry is defined by a murine monoclonal antibody.

    abstract::BALB/c mice were hyperimmunized with ACHN (ATCC CRL 1611, American Type Culture Collection, Rockville, Maryland), a stable in vitro cell line derived from a malignant pleural effusion in a 22-year-old man with renal cell carcinoma. The hyperimmune spleen cells were fused with NS-1 murine myeloma cells using polyethyle...


    pub_type: 杂志文章


    authors: Kochevar J

    更新日期:1987-06-15 00:00:00

  • Alcohol consumption, finasteride, and prostate cancer risk: results from the Prostate Cancer Prevention Trial.

    abstract:BACKGROUND:Current research is inconclusive regarding the relation between alcohol consumption and prostate cancer risk. In this study, the authors examined the associations of total alcohol, type of alcoholic beverage, and drinking pattern with the risk of total, low-grade, and high-grade prostate cancer. METHODS:Dat...


    pub_type: 杂志文章


    authors: Gong Z,Kristal AR,Schenk JM,Tangen CM,Goodman PJ,Thompson IM

    更新日期:2009-08-15 00:00:00

  • Beta-benzene hexachloride in breast adipose tissue and risk of breast carcinoma.

    abstract:BACKGROUND:Epidemiologic studies have recently related benzene hexachloride (BHC) to breast carcinoma risk. Experimental studies have also shown that beta-BHC is weakly estrogenic, hence supporting the alleged association. By directly comparing beta-BHC levels in breast adipose tissue from incident breast carcinoma cas...


    pub_type: 杂志文章


    authors: Zheng T,Holford TR,Mayne ST,Owens PH,Ward B,Carter D,Dubrow R,Zahm SH,Boyle P,Tessari J

    更新日期:1999-05-15 00:00:00

  • Histologic review of breast cancer cases in survivors of atomic bombs in Hiroshima and Nagasaki, Japan.

    abstract::A panel of Japanese and American pathologists reviewed existing histologic material used to study breast cancer risk among the A-bomb survivors in Hiroshima and Nagasaki, a population in which incidence studies have found a strong relationship between breast cancer risk and radiation dose. The primary charge to the pa...


    pub_type: 杂志文章


    authors: Tokuoka S,Asano M,Yamamoto T,Tokunaga M,Sakamoto G,Hartmann WH,Hutter RV,Land CE,Henson DE

    更新日期:1984-09-01 00:00:00

  • The role of sexuality symptoms in myeloproliferative neoplasm symptom burden and quality of life: An analysis by the MPN QOL International Study Group.

    abstract:BACKGROUND:Patients with myeloproliferative neoplasms (MPNs) including polycythemia vera, essential thrombocythemia, and myelofibrosis, are faced with oppressive symptom profiles that compromise daily functioning and quality of life. Among these symptoms, sexuality-related symptoms have emerged as particularly prominen...


    pub_type: 杂志文章


    authors: Geyer HL,Andreasson B,Kosiorek HE,Dueck AC,Scherber RM,Martin KA,Butler KA,Harrison CN,Radia DH,Cervantes F,Kiladjian JJ,Reiter A,Birgegard G,Passamonti F,Senyak Z,Vannucchi AM,Paoli C,Xiao Z,Samuelsson J,Mesa RA

    更新日期:2016-06-15 00:00:00

  • Prognostic factors in soft tissue sarcomas. A multivariate analysis of 109 cases.

    abstract::Prognostic factors were evaluated in 109 soft tissue sarcomas of the extremities, walls of the trunk, head, and neck. All lesions were graded according to the systems proposed by the National Cancer Institute (NCI) and the French Federation of Cancer Centers (FNCLCC), and a correlation was found between tumor grade an...


    pub_type: 杂志文章,评审


    authors: Mandard AM,Petiot JF,Marnay J,Mandard JC,Chasle J,de Ranieri E,Dupin P,Herlin P,de Ranieri J,Tanguy A

    更新日期:1989-04-01 00:00:00

  • Cisplatin neuropathy. Risk factors, prognosis, and protection by WR-2721.

    abstract::A prospective study of patients receiving cis-diaminedichloroplatin II (DDP) was carried out to determine if risk factors could be identified related to the patient's living habits or past medical history that would predict in which patients DDP neuropathy might develop. Sixty-nine patients receiving six different com...


    pub_type: 杂志文章


    authors: Mollman JE,Glover DJ,Hogan WM,Furman RE

    更新日期:1988-06-01 00:00:00

  • Oncofertility and preservation of reproductive capacity in children and young adults.

    abstract::With increasing numbers of survivors from cancer at a young age, the issue of fertility preservation has assumed greater importance. This review describes normal ovarian and testicular function and summarizes what is known about the effect of chemotherapy and radiotherapy on the gonads and uterus. All young patients w...


    pub_type: 杂志文章,评审


    authors: Wallace WH

    更新日期:2011-05-15 00:00:00