Primary female urethral carcinoma. A retrospective comparison of different treatment techniques.

abstract：:The two cancers specific to women for which substantial research on their relationship to exogenous estrogens has been reported are endometrial cancer and breast cancer. With the former, the link to estrogen use is well established. The estrogen use patterns associated with increased risk of endometrial cancer are cha...

journal_title：Cancer

authors： Hulka BS

更新日期：1987-10-15 00:00:00

abstract：BACKGROUND:Previous reports suggesting a correlation between lymphoproliferative disease and serum levels of beta-2-microglobulin (beta-2M) and in vitro data indicating a role of cytokines in the production of beta-2M prompted a study of serum and urine beta-2M concentration in patients with hemophagocytic syndrome (HP...

journal_title：Cancer

authors： Hibi S,Ikushima S,Fujiwara F,Hashida T,Tsunamoto K,Todo S,Imashuku S

更新日期：1995-04-01 00:00:00

abstract：:Five carcinoid tumors of the thymus were screened immunohistochemically for the occurrence of neuropeptides (ACTH, calcitonin, calcitonin gene-related peptide, cholecystokinin, gastrin, neurotensin, somatostatin, substance P), as well as of serotonin, chromogranin A, and neuron-specific enolase. Most of the patients e...

journal_title：Cancer

authors： Herbst WM,Kummer W,Hofmann W,Otto H,Heym C

更新日期：1987-11-15 00:00:00

abstract：BACKGROUND:Ultrasound (US) is more sensitive than physical examination alone in determining axillary lymph node involvement during preliminary staging of breast carcinoma. Due to occasional overlap of sonographic features of benign and indeterminate lymph nodes, fine-needle aspiration (FNA) of sonographically indetermi...

journal_title：Cancer

authors： Krishnamurthy S,Sneige N,Bedi DG,Edieken BS,Fornage BD,Kuerer HM,Singletary SE,Hunt KK

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:Despite extensive investigation, the role of MDR of human cancer remains unclear. Canine lymphoma is a spontaneously arising correlate of human non-Hodgkin's lymphoma that may complement other in vivo models for investigation of issues related to MDR. METHODS:Immunoreactivity of primary antibodies to the hu...

journal_title：Cancer

authors： Lee JJ,Hughes CS,Fine RL,Page RL

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Case reports have associated neuroblastoma, a cancer derived from the embryonal neural crest, with aganglionosis coli and neurofibromatosis type I. The aim of the current study was to test the hypothesis that neuroblastoma is part of a global defect in neurodevelopment. METHODS:Neuropathologic findings from...

journal_title：Cancer

authors： Blatt J,Hamilton RL

更新日期：1998-04-15 00:00:00

abstract：BACKGROUND:Preclinical and clinical data suggest that both leucovorin (LV) and interferon (IFN) can augment the cytotoxic effects of 5-fluorouracil (5-FU). Based on the rationale of biochemical double modulation, the current Phase II study was undertaken. METHODS:Thirty-two previously untreated patients with advanced ...

journal_title：Cancer

authors： Scheithauer W,Pfeffel F,Kornek G,Marczell A,Wiltschke C,Funovics J

更新日期：1992-10-01 00:00:00

abstract：:The records of 1,497 patients with histologically proven adenocarcinoma of the stomach were reviewed from Charity Hospital over the 25-year period, 1948 to 1973. The operability rate was 82% and the resectability rate was 48%. In this series gastric carcinoma predominated in males and Negroes. Necropsy studies indicat...

journal_title：Cancer

authors： Dupont JB Jr,Lee JR,Burton GR,Cohn I Jr

更新日期：1978-03-01 00:00:00

abstract：:The evidence that various endogenous and exogenous sex hormones play a role in the etiology of breast cancer is reviewed. It is hypothesized that prolonged exposure to normal levels of ovarian estrogens and cyclic progesterone resulting from early menarche and late menopause, and primarily willful nulliparity and late...

journal_title：Cancer

authors： Thomas DB

更新日期：1984-02-01 00:00:00

abstract：BACKGROUND:A Phase II study with carboplatin, methotrexate, and vinblastine (CAMV) was conducted with patients who had advanced urothelial cancer to investigate the activity and toxicity of carboplatin when used in combination chemotherapy. METHODS:Thirty-six patients with advanced urothelial cancer were treated with ...

journal_title：Cancer

authors： Boccardo F,Pace M,Guarneri D,Canobbio L,Curotto A,Martorana G

更新日期：1994-04-01 00:00:00

abstract：:Lobular carcinoma may arise within the epithelial component of fibroadenoma of the breast, as evidenced by 5 cases reported from the files of the Mayo Clinic and 21 cases cited in the literature. The 5 cases reported here occurred in a series of 4000 cases of fibroadenoma during a 43-year period. Lobular carcinoma is ...

journal_title：Cancer

authors： Buzanowski-Konakry K,Harrison EG Jr,Payne WS

更新日期：1975-02-01 00:00:00

abstract：:Spleen from nine patients with hairy-cell leukemia (HCL) were studied for ultrastructural alterations. In all cases, hairy cells with typical ultrastructural characteristics were observed within splenic cords and sinuses. Hairy cells had numerous cytoplasmic processes that interdigitated with cytoplasmic processes of ...

journal_title：Cancer

authors： Pilon VA,Davey FR,Gordon GB,Jones DB

更新日期：1982-04-15 00:00:00

abstract：:Categories of objective response to chemotherapy for 460 advanced relapsing prostate cancer patients evaluated in the initial first four randomized clinical trials of the National Prostatic Cancer Project were compared by survival and other patient and disease characteristics. The response criteria for stable were sho...

journal_title：Cancer

authors： Slack NH,Mittelman A,Brady MF,Murphy GP

更新日期：1980-12-01 00:00:00

abstract：BACKGROUND:Genes involved in the angiopoietin and pericyte pathways may become escape mechanisms under antivascular endothelial growth factor (anti-VEGF) therapy. The authors investigated whether variations within genes in these pathways are associated with clinical outcome in patients with colorectal liver metastases ...

journal_title：Cancer

authors： Stremitzer S,Zhang W,Yang D,Ning Y,Stintzing S,Sebio A,Sunakawa Y,Yamauchi S,Matsusaka S,El-Khoueiry R,Stift J,Wrba F,Gruenberger T,Lenz HJ

更新日期：2015-06-01 00:00:00

abstract：:Without organized clinical trials, we are doomed to repeat our mistakes endlessly. There are many genuine conflicts of interest intrinsic to clinical research. Some of these arise from the necessity of admitting that we as physicians do not know the best way to treat every disease or each patient and that all treatmen...

journal_title：Cancer

authors： Hrushesky WJ

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:The association of increasing radiotherapy (RT) dose with reduced biochemical failure (BF) is accepted widely. However, there is little direct evidence that dose escalation has an impact on distant metastasis (DM) or overall mortality (OM). These associations were examined in the current study. METHODS:The ...

journal_title：Cancer

authors： Jacob R,Hanlon AL,Horwitz EM,Movsas B,Uzzo RG,Pollack A

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Although prostate carcinoma is not widely recognized as a familial cancer, familial aggregation of this disease has been shown in some retrospective case-control studies. To study familial prostate cancer in Sweden, a population-based cohort study was performed, that attempted to avoid possible bias connecte...

journal_title：Cancer

authors： Grönberg H,Damber L,Damber JE

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:This study sought to evaluate patient-reported health-related quality of life following proton therapy for prostate cancer in men ≤ 60 years old. METHODS:Between August 2006 and January 2010, 262 hormone-naive men ≤ 60 years old were treated with definitive proton therapy for prostate cancer. Before treatme...

journal_title：Cancer

authors： Hoppe BS,Nichols RC,Henderson RH,Morris CG,Williams CR,Costa J,Marcus RB Jr,Mendenhall WM,Li Z,Mendenhall NP

更新日期：2012-09-15 00:00:00

abstract：:Between the years 1973-1977, 152 male patients from 28 participating Veterans Hospitals with histologically proven nonresectable cancer of the pancreas were randomized in a two-arm study. The treated group was to receive combination chemotherapy with 5-FU and CCNU, and the controls were to receive no chemotherapy. Bot...

journal_title：Cancer

authors： Frey C,Twomey P,Keehn R,Elliott D,Higgins G

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Endometrial carcinoma is one of the most frequent malignancies in the female genital tract, and its incidence has been increasing in Japan. Histologic grade is an important factor for organizing treatment strategies, including hormone therapy, and for predicting the prognosis of the patient. The objective of...

journal_title：Cancer

authors： Nishimura Y,Watanabe J,Jobo T,Hattori M,Arai T,Kuramoto H

更新日期：2005-02-25 00:00:00

abstract：BACKGROUND:In a previous clinical trial, the authors disclosed that the expression of tumor cell motility factor gp78hAMFR correlates with tumor progression in patients with bladder carcinoma. This study was initiated to evaluate whether the combination of cytostatic drugs with an antimotility factor has an effect on c...

journal_title：Cancer

authors： Otto T,Bex A,Krege S,Walz PH,Rübben H

更新日期：1997-08-01 00:00:00

abstract：:An in vivo model is described for assessing the antitumor activity of chemotherapeutic agents. Tumors derived from human colon carcinoma cell lines injected into antithymocyte serum (ATS) immunosuppressed mice were used. In this system, both antitumor effects and host toxicity can be quantitated, permitting calculatio...

journal_title：Cancer

authors： Tibbetts LM,Chu MY,Hager JC,Dexter DL,Calabresi P

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:The frequency of mutant p53 in bone marrow metastases of patients with carcinoma of the prostate (CaP) and in matched sets of metastatic and primary lesions from the same patients was investigated. The data were examined in relation to prior treatment with androgen ablation (AA) therapy and were compared wit...

journal_title：Cancer

authors： Meyers FJ,Gumerlock PH,Chi SG,Borchers H,Deitch AD,deVere White RW

更新日期：1998-12-15 00:00:00

abstract：BACKGROUND:Breast conservation surgery (BCS) and mastectomy have equivalent survival outcomes for women with breast carcinoma, but treatment decisions are affected by many factors. The current study evaluated the impact of patient and physician factors on surgical decision-making. METHODS:Statistical analyses were per...

journal_title：Cancer

authors： Chagpar AB,Studts JL,Scoggins CR,Martin RC 2nd,Carlson DJ,Laidley AL,El-Eid SE,McGlothin TQ,Noyes RD,McMasters KM

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:To the authors' knowledge, there are few studies to date regarding colorectal cancer (CRC) beliefs, knowledge, and screening among multiple Asian American populations, who are reported to have lower CRC screening rates compared with white individuals. The current study was performed to assess knowledge and b...

journal_title：Cancer

authors： Tran MT,Jeong MB,Nguyen VV,Sharp MT,Yu EP,Yu F,Tong EK,Kagawa-Singer M,Cuaresma CF,Sy AU,Tsoh JY,Gildengorin GL,Stewart SL,Nguyen TT

更新日期：2018-04-01 00:00:00

abstract：:The pathologic features, clinical presentation and natural history of hepatocellular carcinoma (HCC) developing in the noncirrhotic liver were studied in 61 patients against a background of 63 patients seen concurrently with HCC complicating cirrhosis. Noncirrhotic HCC had a bimodal age distribution, with females pred...

journal_title：Cancer

authors： Smalley SR,Moertel CG,Hilton JF,Weiland LH,Weiand HS,Adson MA,Melton LJ 3rd,Batts K

更新日期：1988-10-01 00:00:00

abstract：:In 230 cases of chronic lymphocytic leukemia (CLL), marker analysis was performed with rosette techniques and a panel of xeno-antisera. A monoclonal B-cell proliferation was found in the majority of cases (94%). In most cases, the B-cells carried IgM, with or without IgD. Cytoplasmic immunoglobulin-inclusion bodies we...

journal_title：Cancer

authors： van der Reijden HJ,van der Gaag R,Pinkster J,Rümke HC,van't Veer MB,Melief CJ,von dem Borne AE

更新日期：1982-12-15 00:00:00

abstract：:Individualization of treatment using judicious combinations of external and intracavitary irradiation remains the cornerstone of the radiation management of carcinoma of the cervix. The inherent propensity of this cancer to either confine itself to the pelvis or else spread in a systematic and predictable manner throu...

journal_title：Cancer

authors： Rotman M,John M,Boyce J

更新日期：1981-07-15 00:00:00

abstract：:In the course of administration of an immunopotentiator, streptococcal agent OK-432, a patient with lung cancer was found to have severe anemia and a strongly positive antiglobulin test. In the absence of the drug, eluates from the patient's erythrocytes reacted strongly by the indirect antiglobulin test with a panel ...

journal_title：Cancer

authors： Nomura S,Kanoh T

更新日期：1987-04-15 00:00:00

abstract：BACKGROUND:Partial nephrectomy (PN) is recommended for localized T1a (≤4 cm) renal masses and is preferred over radical nephrectomy (RN) for amenable T1b/T2 (>4 cm) tumors. The objective of the current study was to assess overall survival (OS) differences between PN and RN in patients with T1 and T2 renal cell carcinom...

journal_title：Cancer

authors： Ristau BT,Handorf EA,Cahn DB,Kutikov A,Uzzo RG,Smaldone MC

更新日期：2018-10-01 00:00:00