Abstract:
:Comparison of 50 proliferating trichilemmal cysts with 50 "ordinary" trichilemmal cysts indicated that both types almost invariably occurred on the scalps of women, were diagnosed clinically as cysts, followed a benign course, and featured trichilemmal keratinization. A spectrum was observed from trichilemmal cyst with minimal hyperplasia, to full-blown proliferating trichilemmal cyst. Occasionally, patients had ordinary trichilemmal cysts on their scalps associated with a proliferating trichilemmal cyst. In addition to trichilemmal keratinization, which is characteristic of the follicular isthmus, proliferating trichilemmal cysts showed a wider range of differentiation, including features of the follicular infundibulum, the lower nonkeratinizing portion of the follicular outer root sheath, and sebaceous cells. Intense inflammatory infiltrate and cellular atypia, sometimes of significant proportions, were also seen in proliferating trichilemmal cysts. It is concluded that trauma and inflammation may induce a trichilemmal cyst to proliferate and show a broader spectrum of pilosebaceous differentiation and cellular atypia of pseudocarcinomatous proportions, while maintaining its benign biologic behavior.
journal_name
Cancerjournal_title
Cancerauthors
Brownstein MH,Arluk DJdoi
10.1002/1097-0142(19810901)48:5<1207::aid-cncr2820subject
Has Abstractpub_date
1981-09-01 00:00:00pages
1207-14issue
5eissn
0008-543Xissn
1097-0142journal_volume
48pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:Factors that could optimize the management of pediatric spinal cord astrocytoma remain unclear and controversial. METHODS:To determine the factors that influence the prognosis of pediatric patients with spinal cord astrocytomas, a series of 73 consecutive patients at 13 French treatment centers with histolo...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19981201)83:11<2391::aid-c
更新日期:1998-12-01 00:00:00
abstract:BACKGROUND:Single-agent chemotherapy produces partial responses in the range of 7-27% in patients with Stage IV nonsmall cell lung carcinoma (NSCLC). Cisplatin-based combination regimens have achieved higher response rates but with significant toxicity. Two prior studies employing 24-hour infusions of paclitaxel showed...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:
更新日期:1997-02-15 00:00:00
abstract::A case-control study was conducted to assess the risk factors associated with the development of a contralateral primary breast cancer among women who had had a first primary breast cancer. Hospital records were reviewed for 292 women with an incident contralateral breast cancer, diagnosed in one of eight hospitals be...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19880715)62:2<412::aid-cncr28206
更新日期:1988-07-15 00:00:00
abstract::With the improved survival of children with cancer, increased attention is being focused on the health status of survivors. The ultimate objective of this research is to use the results to design and test rational intervention strategies directed toward reduction of morbidity and mortality associated with the diagnosi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930515)71:10+<3406::aid-cncr28
更新日期:1993-05-15 00:00:00
abstract:BACKGROUND:Bone morphogenetic proteins (BMP) induce ectopic bone formation in vivo and may play a role in normal bone development. In addition, bone morphogenetic activity, as measured in a bone-forming assay in immunodeficient, athymic nu/nu mice, is present in a proportion of osteosarcomas; this activity, which may b...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19940101)73:1<85::aid-cncr282073
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Even when they are analogous in microscopic and macroscopic appearance, tumors vary in their response rates to radiotherapy. Cell culture and xenograft experiments with colorectal cell lines have demonstrated that wild-type p53 increases radiosensitivity. Hence, the authors investigated, in a well-defined po...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1999-06-15 00:00:00
abstract:BACKGROUND:The hepatitis activity index (HAI) score describes the histologic status of accompanying chronic hepatitis and was established by pathologists. The aim of this study was twofold: 1) to investigate the correlation between intrahepatic metastatic recurrence (IM) and the HAI score of the noncancerous region of ...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1999-07-15 00:00:00
abstract:BACKGROUND:Seminal vesicle (SV) invasion at the time of radical prostatectomy (RP) generally is considered to be indicative of poor outcome. The authors examined whether there was a subset of men with SV invasion who had long-term prostate-specific antigen (PSA) progression-free survival. METHODS:Data were examined fr...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.20122
更新日期:2004-04-15 00:00:00
abstract::The present overview of advanced prostate cancer required the identification of randomized clinical trials studying the question of maximal androgen blockade versus the classic castration therapy. The heterogeneity of the trials concerned the type of castration (surgical or chemical) and the type of antiandrogen (flut...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19931215)72:12+<3841::aid-cncr28
更新日期:1993-12-15 00:00:00
abstract::A unique case of malignant histiocytosis (MH) is reported. Its origin from the monocyte-macrophage system was indicated by expression of highly specific myeloid cell markers (My4, MCS2, and cytoplasmic lysozyme), diffuse activity of acid phosphatase and NaF-sensitive alpha-naphthyl acetate esterase, lack of immunologi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19881001)62:7<1306::aid-cncr2820
更新日期:1988-10-01 00:00:00
abstract::Between July 1968 and December 1974, 53 patients with lung cancer were planned for preoperative irradiation and surgery. All patients were considered clinically marginally resectable because of advanced local disease, 4 Stage II patients, with limited pulmonary reserve and 49 Stage III patients. Most patients received...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197805)41:5<2040::aid-cncr282041
更新日期:1978-05-01 00:00:00
abstract::The binding of soybean agglutinin (SBA) lectin to routinely processed surgical pathology material from cases of prostatic hyperplasia, atypical hyperplasia, and adenocarcinoma was studied using an immunoperoxidase technique. Positive staining was obtained in eight of eight cases of nodular hyperplasia, eight of eight ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19890415)63:8<1583::aid-cncr2820
更新日期:1989-04-15 00:00:00
abstract::The difficulties encountered in establishing a diagnosis of a malignant peritoneal mesothelioma are emphasized in a patient who developed the lesion 16 years after radiation therapy for a seminoma of the testis. Historically, histologically, electron microscopically, and by microincineration, there was no evidence of ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197909)44:3<914::aid-cncr2820440
更新日期:1979-09-01 00:00:00
abstract::We have tested methyl glyoxal bis-guanyl hydrazone (NSC 32946) for antitumor activity in patients with colorectal carcinoma and non-small cell bronchogenic carcinoma. The drug dose was 500 mg/m2 administered by single weekly injection, and with a provision dose escalation. No responses were seen in 38 evaluable patien...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19821001)50:7<1258::aid-cncr2820
更新日期:1982-10-01 00:00:00
abstract:BACKGROUND:The current study evaluated the efficacy of a 10-week, group-based, cognitive-behavioral stress management (CBSM) intervention relative to a half-day seminar in improving quality of life (QoL) among men who were treated for localized prostate carcinoma (PC) with either radical prostatectomy (RP) or radiation...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/cncr.11894
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Angiotropic large cell lymphoma (ALCL) is characterized by the intravascular proliferation of malignant lymphoid cells in small and medium-sized blood vessels. In the current study, the authors report an unusual case in which the initial presentation of the ALCL was that of superior vena cava (SVC) syndrome....
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20001215)89:12<2515::aid-cncr1>3
更新日期:2000-12-15 00:00:00
abstract::Management of testis cancer in children differs from that in adults due to the histological types and varying tolerances to chemotherapy agents. Embryonal adrenocarcinoma (endodermal sinus tumor, Teilum's tumor) is a tumor of infancy and young children and less aggressive than other testis cancers. Most cases require ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.1980.45.s7.1803
更新日期:1980-04-01 00:00:00
abstract::Aspergillus infection can be a major cause of morbidity in immunocompromised patients, especially when there is pulmonary involvement. Diagnosis of aspergillosis is often complicated by the varied clinical presentation and compromised medical status of such patients. Four cases of head and neck Aspergillus infections ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860315)57:6<1092::aid-cncr2820
更新日期:1986-03-15 00:00:00
abstract:BACKGROUND:Chordoma and chondrosarcoma of the skull base are frequently amalgamated because of similar anatomic location, clinical presentation, and radiologic findings. The chondroid chordoma variant has been reported to carry a better prognosis. The objective of the current study was to investigate the distinctions b...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23073
更新日期:2007-12-01 00:00:00
abstract::During the past eight years, 137 patients with mycosis fungoides were given total skin electron beam therapy (TSEB) using 2.5 to 4 MeV electrons. A single treatment delivers 400 rads to the entire skin surface, and patients are treated once a week for six to eight consecutive weeks. All have been followed for a median...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810301)47:5<870::aid-cncr28204
更新日期:1981-03-01 00:00:00
abstract::Chemotherapy of advanced stages of large bowel cancer has until recently made little progress since the introduction of 5-FU 16 years ago. While survival is improved for patients who respond, 5-FU alone has made little impact on life span of the overall population of patients. Mitomycin-C and the chloroethyl nitrosour...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(197512)36:6<2418::aid-cncr282036
更新日期:1975-12-01 00:00:00
abstract:BACKGROUND:Knowledge of the expression of the galectins in human colon carcinomas is mainly restricted to galectin-3 and, to a lesser extent, galectin-1. The current study analyzed the prognostic values contributed by galectin-1, galectin-3, galectin-4, and galectin-8 in cases of colon carcinoma. METHODS:The authors s...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11268
更新日期:2003-04-15 00:00:00
abstract::Using a modified Feulgen hydrolysis procedure and integrating microdensitometry, the acid-labile nuclear DNA in exfoliated cervical epithelial cells was quantified in a range of histologically confirmed cervical intraepithelial neoplasia (CIN), invasive cancer, and normal controls. The mean relative optical densities ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910615)67:12<3104::aid-cncr282
更新日期:1991-06-15 00:00:00
abstract::Unnecessary, inappropriate, and futile care are given in all areas of health care including cancer care. Not only does such care increase costs and waste precious resources, but patients may have adverse outcomes when the wrong care is given. One of the ways to address this issue is to measure performance with the use...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19980515)82:10+<2016::aid-
更新日期:1998-05-15 00:00:00
abstract:BACKGROUND:Lung carcinoma remains the major cause of cancer death in North America and is even more common among military veterans. The objective of this study was to determine whether there were differences in the characteristics and survival of Pennsylvania patients with lung carcinoma in the Veterans Administration ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21228
更新日期:2005-08-15 00:00:00
abstract:BACKGROUND:Gastrointestinal stromal tumors (GISTs) historically were grouped with leiomyosarcomas (LMSs) based on their morphologic similarities; however, recently, GIST was established unequivocally as a distinct type of sarcoma based on its molecular features and response to imatinib treatment. METHODS:To gain furth...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25594
更新日期:2011-01-15 00:00:00
abstract:BACKGROUND:There is no clear consensus between pediatric and adult providers about the treatment of adolescents and young adults (AYAs) with Hodgkin lymphoma (HL). METHODS:Failure-free survival (FFS) and overall survival (OS) were compared between 114 patients ages 17 to 21 years with HL who were treated on the Easter...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30979
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:The National Quality Forum endorses the recommendation of examining at least 12 lymph nodes (LNs) from colorectal cancer (CRC) specimens. However, heterogeneity in LN harvest exists. The objective of this study was to investigate the clinicopathologic factors that influence LN yield. METHODS:The authors use...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25032
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Chronic myeloid leukemia (CML) can be treated effectively with tyrosine kinase inhibitor therapy directed at BCR-ABL, but access to care, medication cost, and adherence may be barriers to treatment. This study was designed to determine whether the insurance status at diagnosis influences CML patient outcomes...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30639
更新日期:2017-07-01 00:00:00
abstract::To assess the importance of radiation dose fraction size in the treatment of malignant melanomas, the records of 48 patients (83 sites) treated at Tufts-New England Medical Center from 1971 to 1979 have been retrospectively reviewed. During this period, the dose fractionation schemes evolved from standard fraction siz...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810315)47:6<1262::aid-cncr2820
更新日期:1981-03-15 00:00:00