Radiation therapy of malignant melanomas: an evaluation of clinically used fractionation schemes.

Abstract:

:To assess the importance of radiation dose fraction size in the treatment of malignant melanomas, the records of 48 patients (83 sites) treated at Tufts-New England Medical Center from 1971 to 1979 have been retrospectively reviewed. During this period, the dose fractionation schemes evolved from standard fraction size to large-dose techniques. Radiation fraction size was observed to be the major factor in the clinical response of melanoma. Fractions of 600-800 rad resulted in the best overall response (80%). The rapid fractionation scheme of 800-400-400 rad on successive days resulted in intermediate response (58%) and may be useful for the palliative treatment of selected patients.

journal_name

Cancer

journal_title

Cancer

authors

Strauss A,Dritschilo A,Nathanson L,Piro AJ

doi

10.1002/1097-0142(19810315)47:6<1262::aid-cncr2820

subject

Has Abstract

pub_date

1981-03-15 00:00:00

pages

1262-6

issue

6

eissn

0008-543X

issn

1097-0142

journal_volume

47

pub_type

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