Evolution of carcinoma in the extrahepatic bile ducts.

Abstract:

:The histopathology of 43 cases of carcinoma in the extrahepatic bile ducts was reported. All four cases of noninfiltrating carcinoma were papillary or polypoid in gross shape. Only one of the eight cases of papillary or polypoid cancers penetrated beyond the fibromuscular layer of the bile ducts, while most cases of nodular or flat cancers spread deeper than the fibromuscular layer. Adenomatous residue was found in 9 (21.4%) of the total 43 cases, and was particularly frequent in papillary or polypoid cancers (6 [75.0%] of 8 cases). It is likely that early cancers were usually polypoid or papillary in gross shape and that most carcinomas arose from a pre-existing adenoma. Carcinoma associated with a choledochal cyst was found in two cases. Multiple carcinomas were seen in one case. Three cases of carcinoma in the extrahepatic bile ducts were associated with carcinoma of the gallbladder.

journal_name

Cancer

journal_title

Cancer

authors

Kozuka S,Tsubone M,Hachisuka K

doi

10.1002/1097-0142(19840701)54:1<65::aid-cncr282054

subject

Has Abstract

pub_date

1984-07-01 00:00:00

pages

65-72

issue

1

eissn

0008-543X

issn

1097-0142

journal_volume

54

pub_type

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