Patterns of the first lymph node metastases in patients with cutaneous malignant melanoma of axial localization.

Abstract:

:At the Finsen Institute, Copenhagen, from 1971 to 1981, 134 patients were treated for lymph node metastases from primary cutaneous malignant melanoma of axial localization (e.g., in the head and neck and trunk), where metastases to regional lymph node groups were the first sign of dissemination. Due to the lack of sufficient clinical data, 27 patients were excluded from the study. Median time from excision of primary tumor to diagnosis of node metastases was 11 months. In 42 of 85 (49%) patients with truncal melanoma, the primary tumor was placed in the lymphatic water-shed areas. Two patients among this group showed bilateral simultaneous metastases to two different node groups. In the remaining 43 patients with truncal tumors located outside water-shed areas, node metastases developed in unexpected groups in seven (16%) patients. Of 22 patients with head and neck tumors, two (9%) patients demonstrated metastases to distant lymph node groups without metastases to the regional node basins.

journal_name

Cancer

journal_title

Cancer

authors

Lock-Andersen J,Partoft S,Jensen MG

doi

10.1002/1097-0142(19881101)62:9<2073::aid-cncr2820

subject

Has Abstract

pub_date

1988-11-01 00:00:00

pages

2073-7

issue

9

eissn

0008-543X

issn

1097-0142

journal_volume

62

pub_type

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