Surgery for colorectal carcinoma.

abstract：BACKGROUND:Investigations regarding the impact of tumor biology after surgical management of colorectal liver metastasis have focused largely on overall survival. We investigated the impact of codon-specific KRAS mutations on the rates and patterns of recurrence in patients after surgery for colorectal liver metastasis...

journal_title：Cancer

authors： Margonis GA,Kim Y,Sasaki K,Samaha M,Amini N,Pawlik TM

更新日期：2016-09-01 00:00:00

abstract：:Methionine-depleting total parenteral nutrition (methionine-depleting TPN), which infuses an amino acid solution devoid of L-methionine and L-cysteine as the sole protein source, showed enhancement of the effect of several anti-cancer agents. In this study, the combined effect of the methionine-depleting TPN with the ...

journal_title：Cancer

authors： Goseki N,Yamazaki S,Endo M,Onodera T,Kosaki G,Hibino Y,Kuwahata T

更新日期：1992-04-01 00:00:00

abstract：:Initial biopsy and resection specimens from 78 cerebral astrocytomas with anaplastic foci occurring in adults were examined for the presence of five specific histologic features traditionally considered indicative of anaplasia. Anaplastic astrocytomas with foci of tumor necrosis had been classified as glioblastoma mul...

journal_title：Cancer

authors： Fulling KH,Garcia DM

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:There is global variation in the onset of hepatocellular carcinoma (HCC). The objective of the current study was to investigate the impact of country of birth on age at the time of HCC diagnosis in the United States. METHODS:Incident HCC cases diagnosed between 2000 and 2012 in the Surveillance, Epidemiolog...

journal_title：Cancer

authors： Yang JD,Altekruse SF,Nguyen MH,Gores GJ,Roberts LR

更新日期：2017-01-01 00:00:00

abstract：:On the basis of previous findings at this institution, VM-26 and Cytosine Arabinoside (ara-C) were used in combination to treat 33 children with refractory acute lymphocytic leukemia (ALL). Chemotherapy was given by vein twice a week for four weeks at dosage of 300 mg/m2 for ara-C and 50, 75, 110, 165, or 200 mg/m2 fo...

journal_title：Cancer

authors： Rivera G,Aur RJ,Dahl GV,Pratt CB,Wood A,Avery TL

更新日期：1980-03-15 00:00:00

abstract：:A 49-year-old white woman with refractory anemia subsequently developed acute myelomonocytic leukemia with paraproteinemia 12 months later. The paraprotein was characterized as immunoglobulin G, type kappa, and the Bence Jones protein as free kappa chains. Further studies, including electron microscopy, cytochemistry,...

journal_title：Cancer

authors： Law IP,Koch FJ,Cannon GB,Herberman RB,Oldham RK

更新日期：1976-03-01 00:00:00

abstract：:Retinitis pigmentosa, a hereditary disease characterized by progressive retinal degeneration and blindness, has been associated with numerous diseases. We report the first association between retinitis pigmentosa and colon cancer in 3 of 53 hospitalized patients with retinitis pigmentosa at the Massachusetts General H...

journal_title：Cancer

authors： Winzelberg GG,Greenstein R,Ferrucci JT Jr

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:Neuropilins (NRPs) are characterized as coreceptors of vascular endothelial growth factor (VEGF). In the current study, the authors assessed the expression of NRPs, VEGF, and vascular endothelial growth factor receptors (VEGFRs), as well as VEGF-induced cell proliferation, in pancreatic carcinoma cell lines ...

journal_title：Cancer

authors： Li M,Yang H,Chai H,Fisher WE,Wang X,Brunicardi FC,Yao Q,Chen C

更新日期：2004-11-15 00:00:00

abstract：:In contrast with the expectations of the authors and with reports suggesting a decline in risk for scrotal cancer, Connecticut Tumor Registry data neither showed detectable decrease in risk over the 45-year-period for all 95 scrotal malignancies nor for the 71 epithelial cancers. The age distribution of scrotal cancer...

journal_title：Cancer

authors： Roush GC,Schymura MJ,Flannery JT

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:The objective of this study was to determine the potential economic implications resulting from using exemestane (EXE), a new steroidal, irreversible aromatase inactivator, compared with megestrol acetate (MA) in patients with advanced breast carcinoma. METHODS:The model used the clinical results from the m...

journal_title：Cancer

authors： Hillner BE,Radice D

更新日期：2001-02-01 00:00:00

abstract：:The serious import of breast cancer lies in its potential for metastatic spread, which probably starts early in the course of the disease. Detection of the lesion when immunocompetence can control the metastases leads to long-term survival. This usually involves detection of unsuspected, preclinical disease. This is t...

journal_title：Cancer

authors： Strax P

更新日期：1984-02-01 00:00:00

abstract：:A case of angiosarcoma of the breast with a fatal outcome is reported, and the world literature on this rare type of breast tumor is reviewed. Familiarity with the clinical and pathologic features of this entity is essential in avoiding underdiagnosis and delay of definitive treatment. The three-year survival rate of ...

journal_title：Cancer

authors： Chen KT,Kirkegaard DD,Bocian JJ

更新日期：1980-07-15 00:00:00

abstract：:Between February 1980 and December 1985, splenectomies were performed in 13 patients with advanced (Stage III and IV) chronic lymphocytic leukemia (CLL). Patients had advanced disease for a median of 32 months at the time of splenectomy and all were refractory to chemotherapy. All patients were anemic with a median he...

journal_title：Cancer

authors： Stein RS,Weikert D,Reynolds V,Greer JP,Flexner JM

更新日期：1987-05-15 00:00:00

abstract：BACKGROUND:Despite optimal therapy with surgery and radiotherapy, the prognosis of patients with glioblastomas remains poor. Stereotactic brachytherapy involves the accurate placement of radioactive isotopes within brain tumors, significantly increasing the dose of radiation that can be delivered to the tumor bed witho...

journal_title：Cancer

authors： Wen PY,Alexander E 3rd,Black PM,Fine HA,Riese N,Levin JM,Coleman CN,Loeffler JS

更新日期：1994-06-15 00:00:00

abstract：:The following case report describes a 22-year-old healthy man, non-smoker, non-drinker, who developed a squamous cell carcinoma of the buccal mucosa. The appearance of this unusual tumor in an unexpected clinical setting was unexplained until it was discovered that the patient had a lifetime habit of chewing plastic m...

journal_title：Cancer

authors： Casterline CL,Casterline PF,Jaques DA

更新日期：1977-04-01 00:00:00

abstract：BACKGROUND:Chordoma and chondrosarcoma of the skull base are frequently amalgamated because of similar anatomic location, clinical presentation, and radiologic findings. The chondroid chordoma variant has been reported to carry a better prognosis. The objective of the current study was to investigate the distinctions b...

journal_title：Cancer

authors： Almefty K,Pravdenkova S,Colli BO,Al-Mefty O,Gokden M

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Little is known about the natural growth characteristics of untreated glioblastoma before surgical or therapeutic intervention, because patients are rapidly treated after preliminary radiographic diagnosis. Understanding the growth characteristics of uninhibited human glioblastoma may be useful for character...

journal_title：Cancer

authors： Ellingson BM,Nguyen HN,Lai A,Nechifor RE,Zaw O,Pope WB,Yong WH,Nghiemphu PL,Liau LM,Cloughesy TF

更新日期：2016-06-01 00:00:00

abstract：:Regressing atypical histiocytosis (RAH) of skin is a cutaneous noduloulcerative proliferation of atypical neoplastic histiocytes with concomitant polymorphous inflammation, frequently pronounced epidermal hyperplasia, and an unexpectedly indolent biologic course. Spontaneous regression and recurrence without systemic ...

journal_title：Cancer

authors： Flynn KJ,Dehner LP,Gajl-Peczalska KJ,Dahl MV,Ramsay N,Wang N

更新日期：1982-03-01 00:00:00

abstract：BACKGROUND:Research suggests that patients' end-of-life (EOL) care is determined primarily by the medical resources available, and not by patient preferences. The authors examined whether patients' desire for life-extending therapy was associated with their EOL care. METHODS:Coping with Cancer is a multisite, prospect...

journal_title：Cancer

authors： Wright AA,Mack JW,Kritek PA,Balboni TA,Massaro AF,Matulonis UA,Block SD,Prigerson HG

更新日期：2010-10-01 00:00:00

abstract：:The aims of this study were as follows: to confirm that the presence of estrogen (ER) and progesterone (PgR) receptors is an indicator of clinical behavior of human breast cancer independent of other known prognostic factors; to seek clinical correlates of those receptor values that best predict the overall disease ev...

journal_title：Cancer

authors： Vollenweider-Zerargui L,Barrelet L,Wong Y,Lemarchand-Béraud T,Gómez F

更新日期：1986-03-15 00:00:00

abstract：:Lobular carcinoma in situ (LCIS) has uncertain malignant potential; biologic markers that will identify patients at risk for a poor clinical outcome have been sought actively. Amplification of the c-erbB-2 protooncogene has been correlated with poor prognosis in invasive mammary carcinoma, and immunohistochemical eval...

journal_title：Cancer

authors： Porter PL,Garcia R,Moe R,Corwin DJ,Gown AM

更新日期：1991-07-15 00:00:00

abstract：:Granulocyte (PMN) directional locomotion (migration) in vitro and in vivo, resting nitroblue tetrazolium (NBT)-reduction and adherence to nylon wool of polymorphonuclear neutrophils (PMN) were assayed in 7 patients with Hodgkin's disease (HD) and in 11 patients with non-Hodgkin's lymphoma (NHL) prior to therapy. In mo...

journal_title：Cancer

authors： Von Fliedner V,Salvatori V,Higby DJ,Stutzman L,Park BH

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND:There is accumulating evidence that galanin receptors (GALRs) may be tumor suppressors in head and neck squamous cell carcinoma (HNSCC). Promoter methylation status and gene expression were assessed in a large panel of head and neck primary tumors, based on the hypothesis that cytosine-guanine dinucleotide (...

journal_title：Cancer

authors： Misawa Y,Misawa K,Kanazawa T,Uehara T,Endo S,Mochizuki D,Yamatodani T,Carey TE,Mineta H

更新日期：2014-01-15 00:00:00

abstract：BACKGROUND:Synovial sarcoma usually arises in the extremities and in close proximity to large joints. Reported examples arising in the anterior abdominal wall are rare. Because most accounts from this location consist of case reports, neither clinical nor prognostic features have been well delineated. METHODS:Twenty-s...

journal_title：Cancer

authors： Fetsch JF,Meis JM

更新日期：1993-07-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to confirm whether black and white women with endometrial cancer are equally tolerant of chemotherapy and identify factors that impact survival. METHODS:A retrospective review of 169 black women and 982 white women with the International Federation of Gynecologists and Obstetri...

journal_title：Cancer

authors： Farley JH,Tian C,Rose GS,Brown CL,Birrer M,Risinger JI,Thigpen JT,Fleming GF,Gallion HH,Maxwell GL

更新日期：2010-01-15 00:00:00

abstract：BACKGROUND:For many childhood cancers, survival is lower among non-Hispanic blacks and Hispanics in comparison with non-Hispanic whites, and this may be attributed to underlying socioeconomic factors. However, prior childhood cancer survival studies have not formally tested for mediation by socioeconomic status (SES). ...

journal_title：Cancer

authors： Kehm RD,Spector LG,Poynter JN,Vock DM,Altekruse SF,Osypuk TL

更新日期：2018-10-15 00:00:00

abstract：:The report describes a clinical trial on conservative surgery in progress at the National Cancer Institute of Milan, Italy. The randomized clinical trial compares radical mastectomy with a more conservative procedure consisting of mammary resection plus axillary dissection plus radiotherapy. The resection comprises an...

journal_title：Cancer

authors： Veronesi U,Banfi A,Saccozzi R,Salvadori B,Zucali R,Uslenghi C,Greco M,Luini A,Rilke F,Sultan L

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:The authors attempted to obtain shared proteins among lung carcinoma cells by column chromatographies. A glycoprotein with approximately 500 kDa isolated from QG56 cells showed an identical amino acid sequence to 90K/Mac-2 binding protein (M2BP). This protein has been reported to be highly expressed and to m...

journal_title：Cancer

authors： Ozaki Y,Kontani K,Hanaoka J,Chano T,Teramoto K,Tezuka N,Sawai S,Fujino S,Yoshiki T,Okabe H,Ohkubo I

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Current techniques to define gastric neoplasia are limited but molecular genetic signatures can categorize tumors and provide biological rationale for predicting clinical behavior. We identified three gene signatures: Chromogranin A (CgA), MAGE-D2 (adhesion), and MTA1 (metastasis) that define gastrointestina...

journal_title：Cancer

authors： Kidd M,Modlin IM,Mane SM,Camp RL,Eick GN,Latich I,Zikusoka MN

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Immune checkpoint inhibitors (ICIs) represent an appealing treatment for patients with advanced urothelial cancer (aUC) and a poor performance status (PS). However, the benefit of ICIs for patients with a poor PS remains unknown. It was hypothesized that a poor Eastern Cooperative Oncology Group (ECOG) PS (≥...

journal_title：Cancer

authors： Khaki AR,Li A,Diamantopoulos LN,Bilen MA,Santos V,Esther J,Morales-Barrera R,Devitt M,Nelson A,Hoimes CJ,Shreck E,Assi H,Gartrell BA,Sankin A,Rodriguez-Vida A,Lythgoe M,Pinato DJ,Drakaki A,Joshi M,Isaacsson Velho P

更新日期：2020-03-15 00:00:00