BRCA1, TP53, and CHEK2 germline mutations in uterine serous carcinoma.

abstract：:Pancreatic carcinomas have been induced in Wistar and W/LEW rats by administration of total azaserine doses of 150-520 mg/kg by injection or oral routes over periods of 5-52 weeks. The latent period for development of invasive carcinomas was 1-2 years, but focal abnormalities in acinar cells appear earlier. The incide...

journal_title：Cancer

authors： Longnecker DS,Roebuck BD,Yager JD Jr,Lilja HS,Siegmund B

更新日期：1981-03-15 00:00:00

abstract：:Retinoblastoma should not be considered as the exceptional childhood cancer that shows dominant inheritance, but rather as the typical childhood cancer that embraces a prezygotic and postzygotic subgroup. Postzygotic cases are conceived as involving mutation as a first step too, but with the mutation in somatic rather...

journal_title：Cancer

authors： Knudson AG Jr

更新日期：1975-03-01 00:00:00

abstract：:The efficacy of mitoxantrone in combination with vinblastine was assessed in 156 patients with metastatic breast cancer who had been treated previously with one or multiple chemotherapeutic regimens. Mitoxantrone was given by random assignment, either as a 10 mg/m2 single intravenous dose or in five consecutive daily ...

journal_title：Cancer

authors： Fraschini G,Yap HY,Mann G,Buzdar AU,Blumenschein GR,Hortobagyi GN

更新日期：1987-10-15 00:00:00

abstract：BACKGROUND:Oral tongue cancer incidence has increased among whites in the United States; however, the cause remains unknown. If an infectious agent is implicated, then elevated risk would be expected among immunosuppressed individuals. METHODS:By using population-based registry linkage information from the US Transpla...

journal_title：Cancer

authors： Tota JE,Engels EA,Madeleine MM,Clarke CA,Lynch CF,Ortiz AP,Hernandez BY,Chaturvedi AK

更新日期：2018-06-15 00:00:00

abstract：:Testicular function was studied in 26 men with sarcoma who received adjuvant treatment with doxorubicin, cyclophosphamide, and high-dose methotrexate (with or without radiotherapy). Testicular size, sperm output, and serum FSH, LH and testosterone levels were assessed after treatment. Five of 17 men who received chemo...

journal_title：Cancer

authors： Shamberger RC,Sherins RJ,Rosenberg SA

更新日期：1981-05-15 00:00:00

abstract：BACKGROUND:Atypia of undetermined significance is a controversial category in thyroid fine-needle aspiration (FNA), not only for its questioned clinical utility, but also for its very existence as an expression of uncertainty. The current study was performed to investigate the potential impact of eliminating this categ...

journal_title：Cancer

authors： Shi Y,Ding X,Klein M,Sugrue C,Matano S,Edelman M,Wasserman P

更新日期：2009-10-25 00:00:00

abstract：:Amyloid as defined by positive Congo red green birefringence and STB red birefringence was observed in the stroma of a tubular carcinoma of minor salivary gland origin. The amyloid exhibited additional histochemical characteristics of immunamyloid, viz., positive DMAB-nitrate and DC-reactions and spontaneous autofluor...

journal_title：Cancer

authors： David R,Buchner A

更新日期：1978-05-01 00:00:00

abstract：BACKGROUND:The current study was performed to describe frequencies and risk factors of altered oral health and odontogenesis in childhood cancer survivors. METHODS:In total, 9308 survivors who were diagnosed between 1970 and 1986 and 2951 siblings from the Childhood Cancer Survivor Study completed a survey that contai...

journal_title：Cancer

authors： Kaste SC,Goodman P,Leisenring W,Stovall M,Hayashi RJ,Yeazel M,Beiraghi S,Hudson MM,Sklar CA,Robison LL,Baker KS

更新日期：2009-12-15 00:00:00

abstract：:Blood was obtained on 414 occasions from 106 children with acute lymphocytic leukemia (ALL) or solid tumors. Resting and stimulated hexose monophosphate shunt (HMPS) activity and unstimulated and stimulated nitroblue tetrazolium (NBT) dye reduction were assessed on each sample. The values obtained were compared to sim...

journal_title：Cancer

authors： Pickering LK,Anderson DC,Choi S,Feigin RD

更新日期：1975-05-01 00:00:00

abstract：:Pituitary adenomas rarely are metastatic. Extracranial visceral metastases of prolactinomas were not previously reported. The authors report a case of a 34-year-old man with a prolactin-producing pituitary carcinoma and histologically proven lung metastases. Pathologic examination of the pulmonary spread included elec...

journal_title：Cancer

authors： Atienza DM,Vigersky RJ,Lack EE,Carriaga M,Rusnock EJ,Tsou E,Cerrone F,Kattah JG,Sausville EA

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:Angiogenesis in individuals with various solid tumors has provided useful information on tumor progression and prognosis, and many examples of mast cell (MC) accumulation coupled with angiogenesis can be found in the literature. METHODS:Utilizing monoclonal antibodies for tryptase that are specific markers ...

journal_title：Cancer

authors： Takanami I,Takeuchi K,Naruke M

更新日期：2000-06-15 00:00:00

abstract：BACKGROUND:Preclinical and clinical data suggest that both leucovorin (LV) and interferon (IFN) can augment the cytotoxic effects of 5-fluorouracil (5-FU). Based on the rationale of biochemical double modulation, the current Phase II study was undertaken. METHODS:Thirty-two previously untreated patients with advanced ...

journal_title：Cancer

authors： Scheithauer W,Pfeffel F,Kornek G,Marczell A,Wiltschke C,Funovics J

更新日期：1992-10-01 00:00:00

abstract：:Carcinoembryonic antigen (CEA) values in 529 patients treated in two consecutive adjuvant chemotherapy protocols were analyzed to determine if CEA values correlated with disease-free status or prognostic utility. CEA values were evaluated preoperatively, before chemotherapy, at the conclusion of chemotherapy, and duri...

journal_title：Cancer

authors： Theriault RL,Hortobagyi GN,Fritsche HA,Frye D,Martinez R,Buzdar AU

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:The incidence of rectal cancer in the United States in young patients is considered to be low. Underestimating this incidence may result in a failure to diagnose younger patients with rectal cancer in a timely manner. METHODS:The authors conducted a retrospective cohort study using Surveillance, Epidemiolog...

journal_title：Cancer

authors： Meyer JE,Narang T,Schnoll-Sussman FH,Pochapin MB,Christos PJ,Sherr DL

更新日期：2010-09-15 00:00:00

abstract：:Four cases of non-Hodgkin's lymphoma (NHL) limited to the larynx are described. All were diffuse, high-grade, B-cell lymphomas of large lymphoid cell type (three centroblastic and one immunoblastic). Immunocytochemistry was performed on three cases; two showed monoclonal cytoplasmic immunoglobulin and one showed monoc...

journal_title：Cancer

authors： Morgan K,MacLennan KA,Narula A,Bradley PJ,Morgan DA

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Resistance to apoptosis is 1 of the key events that confer chemoresistance and is mediated by the overexpression of antiapoptotic proteins, which inhibit caspase activation. The objective of this study was to evaluate whether the activation of an alternative, caspase-independent cell death pathway could prom...

journal_title：Cancer

authors： Alvero AB,Montagna MK,Chen R,Kim KH,Kyungjin K,Visintin I,Fu HH,Brown D,Mor G

更新日期：2009-07-15 00:00:00

abstract：BACKGROUND:If some adenomas do not bleed over several years, they will cause systematic false-negative fecal immunochemical test (FIT) results. The long-term effectiveness of FIT screening has been estimated without accounting for such systematic false-negativity. There are now data with which to evaluate this issue. ...

journal_title：Cancer

authors： van der Meulen MP,Lansdorp-Vogelaar I,van Heijningen EM,Kuipers EJ,van Ballegooijen M

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Humoral hypercalcemia rarely is associated with colorectal carcinoma; to the authors' knowledge only nine cases have been reported to date. METHODS:Two cases of advanced colorectal carcinoma with humoral hypercalcemia of malignancy (HHM) are presented. RESULTS:The two patients had severe hypercalcemia with...

journal_title：Cancer

authors： Lortholary AH,Cadeau SD,Bertrand GM,Guerin-Meyer VI,Gamelin EC,Audran MJ

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Survivors of childhood leukemia/lymphoma are at increased risk for reduced bone mineral density (BMD). The authors sought to determine the frequency of reduced BMD detected by off-therapy surveillance, factors associated with reduced BMD, and the association of reduced BMD with fractures. METHODS:This cross...

journal_title：Cancer

authors： Bloomhardt HM,Sint K,Ross WL,Rotatori J,Ness K,Robinson C,Carpenter TO,Chow EJ,Kadan-Lottick NS

更新日期：2020-01-01 00:00:00

abstract：:Reflected ultrasound scanning (echography) is rapidly developing into a prime tool for tumor diagnosis, outlining, and detection. The principles of echographic diagnosis of neoplasms, the accepted uses in detection and diagnosis, as well as some of the principles of internal and contour patterns are discussed. Echogra...

journal_title：Cancer

authors： Freimanis AK

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:A considerable body of evidence supports the concept that a significant number of cutaneous malignant melanomas progress through a precursor lesion or dysplastic melanocytic nevi (DN). Tumor angiogenesis likely plays a critical role in early development of melanoma, and intermediate biomarkers of angiogenesi...

journal_title：Cancer

authors： Einspahr JG,Thomas TL,Saboda K,Nickolof BJ,Warneke J,Curiel-Lewandrowski C,Ranger-Moore J,Duckett L,Bangert J,Fruehauf JP,Alberts DS

更新日期：2007-12-01 00:00:00

abstract：:The records were reviewed for all patients hospitalized at a pediatric oncology center for complications of leukemia (n = 822) or lymphoma (n = 290) during an 8-year period. The results of surveillance cultures (throat, rectal, and urine) and blood cultures were analyzed to identify cases of Candida tropicalis and C. ...

journal_title：Cancer

authors： Marina NM,Flynn PM,Rivera GK,Hughes WT

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) with portal venous invasion (PVI) has a very poor prognosis, with a median survival of 3 months and virtually no survival at 1 year. The combination of intraarterial 5-fluorouracil (FU) and systemic interferon-alpha (IFNalpha) was recently reported to be effective against HCC w...

journal_title：Cancer

authors： Obi S,Yoshida H,Toune R,Unuma T,Kanda M,Sato S,Tateishi R,Teratani T,Shiina S,Omata M

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:The objective of this analysis was to evaluate the role of autologous stem cell transplantation (ASCT) in prolonging disease free survival (DFS) and overall survival (OS) in patients with chronic myeloid leukemia (CML) who received autografts of Philadelphia chromosome (Ph) positive or Ph negative cell harve...

journal_title：Cancer

authors： Koziner B,Dengra C,Lucero G,Klein G,Cánepa C,Milovic V,Milone G,Robinson A,Cerutti I,Saporito G,Kusminsky G,Milone J,Bordone J,Lastiri F,Argentine Group of Bone Marrow Transplantation.

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Although breast-conserving therapy (tumor excision, axillary node dissection, and postoperative radiation) for women with breast cancer yields survival and local recurrence rates comparable with those of modified radical mastectomy, studies suggest that postoperative radiation leads to capsular contractures ...

journal_title：Cancer

authors： Guenther JM,Tokita KM,Giuliano AE

更新日期：1994-05-15 00:00:00

abstract：BACKGROUND:Antithymocyte globulin (ATG) is an important component of conditioning regimens to prevent severe graft-versus-host disease (GVHD) in patients undergoing unmanipulated, haploidentical stem cell transplantation (haplo-SCT). However, to the authors' knowledge, the optimal dose of ATG is unknown. METHODS:In th...

journal_title：Cancer

authors： Chang YJ,Wang Y,Mo XD,Zhang XH,Xu LP,Yan CH,Chen H,Chen YH,Chen Y,Han W,Wang FR,Wang JZ,Liu KY,Huang XJ

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:The authors purpose in this study was to clarify the difference in terms of clinicopathologic features between gastric cancer (GC) with high numbers of DNA methylated genes and CpG island methylator phenotype (CIMP)-positive GC as originally defined. METHODS:We analyzed DNA methylation of 12 tumor-related g...

journal_title：Cancer

authors： Oue N,Mitani Y,Motoshita J,Matsumura S,Yoshida K,Kuniyasu H,Nakayama H,Yasui W

更新日期：2006-03-15 00:00:00

abstract：:The interferon (IFN) assay of the sera from the 40 patients with head and neck cancer was performed by the plaque-reduction assay with vesicular stomatitis virus in FL cells derived from human amniotic membrane. The patients mainly had Stage III or IV lesion without distant metastasis, and previously had not received ...

journal_title：Cancer

authors： Sato M,Yoshida H,Yanagawa T,Yura Y,Urata M,Atsumi M,Furumoto N,Hayashi Y,Takegawa Y

更新日期：1984-10-01 00:00:00

abstract：:We synthesized doxorubicin (Adriamycin, Adria Laboratories, Columbus, OH)-loaded human albumin microspheres (containing approximately 1% doxorubicin w/w) between 15 and 20 micron in diameter. Intrarenal arterial administration of 99mTC-labeled microspheres demonstrated a high renal entrapment ratio (97% of recovered r...

journal_title：Cancer

authors： Kerr DJ,Willmott N,McKillop JH,Cummings J,Lewi HJ,McArdle CS

更新日期：1988-09-01 00:00:00

abstract：:A case of an acute myocardial infarction occurring in a 19-year-old woman, 27 months after mantle radiotherapy for Stage II-A Hodgkin's disease is described. The coronary arteriogram demonstrated patent and normal coronary arteries, but the echocardiogram revealed pericarditis. The clinical course was further complica...

journal_title：Cancer

authors： Yahalom J,Hasin Y,Fuks Z

更新日期：1983-08-15 00:00:00