Primary hemangiosarcoma of the spleen with angioscintigraphic demonstration of metastases.

Abstract:

:A case of primary hemangiosarcoma of the spleen in a 48-year-old woman is presented. Twenty-eight months after splenectomy the patient developed a severe anemia of the microangiopathic type, thrombocytopenia, and a leukoerythroblastic peripheral blood picture. In contrast to x-ray and conventional 99mTc-methylene-diphosphonate (MDP) bone scintigraphy, which showed only a few minor focal changes in the spine and ribs, angioscintigraphy with in vitro labeled 99mTc-erythrocytes revealed extensive pathologic accumulations throughout the spine, femurs, and the liver, indicating the presence of extremely vascular metastases. Autopsy 15 months later confirmed the scintigraphic findings. Angiography with 99mTc-labeled erythrocytes seems to be useful for monitoring metastases from hemangiosarcomas.

journal_name

Cancer

journal_title

Cancer

authors

Hermann GG,Fogh J,Graem N,Hansen OP,Hippe E

doi

10.1002/1097-0142(19840415)53:8<1682::aid-cncr2820

subject

Has Abstract

pub_date

1984-04-15 00:00:00

pages

1682-5

issue

8

eissn

0008-543X

issn

1097-0142

journal_volume

53

pub_type

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