Adult de novo acute myeloid leukemia with t(6;11)(q27;q23): results from Cancer and Leukemia Group B Study 8461 and review of the literature.

abstract：BACKGROUND:Lenvatinib is an oral, multitargeted tyrosine kinase inhibitor of the vascular endothelial growth factor receptors 1 through 3 (VEGFR1-VEGFR3), fibroblast growth factor receptors 1 through 4 (FGFR1-FGFR4), platelet-derived growth factor receptor α (PDGFRα), ret proto-oncogene (RET), and v-kit Hardy-Zuckerman...

journal_title：Cancer

authors： Cabanillas ME,Schlumberger M,Jarzab B,Martins RG,Pacini F,Robinson B,McCaffrey JC,Shah MH,Bodenner DL,Topliss D,Andresen C,O'Brien JP,Ren M,Funahashi Y,Allison R,Elisei R,Newbold K,Licitra LF,Sherman SI,Ball DW

更新日期：2015-08-15 00:00:00

abstract：:The urinary excretion of nonesterified cholesterol (NEC) in 170 women with cervical and endometrial carcinomas has been investigated. Control patients (236) included: 1) women with other types of (benign and/or malignant diseases of the pelvic organs; 2) patients with non-steroid-related neoplasms; 3) patients with be...

journal_title：Cancer

authors： Acevedo HF,Campbell EA,Frich JC Jr,Merkow LP,Hayeslip D,Gilmore J

更新日期：1975-10-01 00:00:00

abstract：:This is a report of a gastric perforation secondary to a metastasis from a primary squamous cell carcinoma of the lung in a 70-year-old white man who was being treated with cimetidine for a presumed benign gastric ulcer. The literature concerning bronchogenic carcinoma metastasizing to the stomach and small bowel is r...

journal_title：Cancer

authors： Fletcher MS

更新日期：1980-10-15 00:00:00

abstract：BACKGROUND:Melanoma vaccine treatment appears to slow the progression of melanoma in some patients, particularly in patients in whom it stimulates cellular antimelanoma immune responses. The relationship of vaccine-induced antibody responses to clinical outcome is less clear. The purpose of this study was to investigat...

journal_title：Cancer

authors： Miller K,Abeles G,Oratz R,Zeleniuch-Jacquotte A,Cui J,Roses DF,Harris MN,Bystryn JC

更新日期：1995-01-15 00:00:00

abstract：BACKGROUND:Colorectal cancer (CRC) is the third most common cause of cancer deaths; however, rates of regular screening for this cancer are low. A quality improvement (QI) program to increase CRC screening was developed for use in a managed care health plan. METHODS:Thirty-six provider organizations (POs) contracting ...

journal_title：Cancer

authors： Ganz PA,Farmer MM,Belman MJ,Garcia CA,Streja L,Dietrich AJ,Winchell C,Bastani R,Kahn KL

更新日期：2005-11-15 00:00:00

abstract：:Sixteen cases of clear cell adenocarcinoma of the cervix and vagina in young women were studied by electron microscopy and the observations were compared with the light microscopic appearance. Ultrastructurally, the neoplastic cells were found to be of the same basic type, regardless of whether light microscopy disclo...

journal_title：Cancer

authors： Dickersin GR,Welch WR,Erlandson R,Robboy SJ

更新日期：1980-04-01 00:00:00

abstract：:Effective management of hepatic metastases from ocular and cutaneous melanoma remains a major therapeutic challenge. Treatment options include hepatic resection, hepatic intra-arterial (HIA) chemotherapy, chemoembolization, and hepatic perfusions. Evaluating the efficacy of these interventions is limited by the retros...

journal_title：Cancer

authors： Agarwala SS,Eggermont AM,O'Day S,Zager JS

更新日期：2014-03-15 00:00:00

abstract：BACKGROUND:Clinical drug resistance is recognized in patients previously treated with radiotherapy and after chemotherapy. In vitro exposure of mammalian tumor cells to fractionated X-irradiation also resulted in the expression of drug resistance. Analysis of the resistance phenotype of irradiated Chinese hamster ovary...

journal_title：Cancer

authors： Hill BT,Whelan RD,Hurst HC,McClean S

更新日期：1994-06-15 00:00:00

abstract：:The ability of infantile hypercalcemic tumors (three rhabdoid renal tumors, one cellular mesoblastic nephroma, and one hepatoblastoma) to produce parathyroid hormone (PTH) was tested using RNA-DNA hybridization. Results were compared with those obtained in one lung epidermoid carcinoma and one parathyroid adenoma from...

journal_title：Cancer

authors： Rousseau-Merck MF,de Keyzer Y,Bourdeau A,Cournot G,Mercier F,Nezelof C

更新日期：1988-07-15 00:00:00

abstract：:To assess whether chemosensitivity in metastatic soft tissue sarcoma (STS) is influenced by the histologic grade of the tumor, the authors retrospectively analyzed tumor responses to doxorubicin-based chemotherapy in four prospective studies conducted at the Mayo Clinic, Rochester, Minnesota, between 1976 and 1984. A ...

journal_title：Cancer

authors： van Haelst-Pisani CM,Buckner JC,Reiman HM,Schaid DJ,Edmonson JH,Hahn RG

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Telomerase is commonly recognized as an effective anticancer target. The human telomerase reverse transcriptase (hTERT), the rate-limiting component of telomerase, is expressed in most malignant tumors, but it is not found in most normal somatic cells. Here, we report a real-time and noninvasive method to mo...

journal_title：Cancer

authors： Yu ST,Li C,Lü MH,Liang GP,Li N,Tang XD,Wu YY,Shi CM,Chen L,Li CZ,Cao YL,Fang DC,Yang SM

更新日期：2012-04-01 00:00:00

abstract：:A spontaneous complete remission of 34 months' duration was observed in an adult patient with acute myeloblastic leukemia. The remission occurred after a severe febrile pneumonia, which was treated with leukocyte transfusions. At relapse, chromosomal abnormalities reappeared slowly. Such spontaneous complete remission...

journal_title：Cancer

authors： Ifrah N,James JM,Viguie F,Marie JP,Zittoun R

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Renal medullary carcinoma is a rare tumor that is most common in young black men with sickle cell disease or trait. Patients often present with advanced disease at the time of diagnosis, and their prognosis is poor, even with aggressive therapy. The clinical and pathologic features of renal medullary carcino...

journal_title：Cancer

authors： Assad L,Resetkova E,Oliveira VL,Sun W,Stewart JM,Katz RL,Caraway NP

更新日期：2005-02-25 00:00:00

abstract：BACKGROUND:In a recently reported, randomized trial, it was found that a regimen of irinotecan once every 3 weeks for patients with advanced colorectal carcinoma was associated with a lower incidence of severe diarrhea compared with weekly treatment, and both regimens had similar efficacy. METHODS:Resource utilization...

journal_title：Cancer

authors： Earle CC,Kwok A,Gazelle GS,Fuchs CS

更新日期：2004-12-01 00:00:00

abstract：:Urinary polyamine concentrations in 91 samples were assayed in 79 patients with malignant melanoma who were classified as to clinical stage, as well as to activity of disease. Patients with active disease had higher mean polyamine values, increased frequency of polyamine elevations, and increased frequency of two or m...

journal_title：Cancer

authors： Townsend RM,Banda PW,Marton LJ

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:National Cancer Institute (NCI)/National Comprehensive Cancer Network (NCCN)-designated cancer centers (CCs) offer patients state-of-the-art treatment, but their impact on multiple myeloma (MM) patient outcomes has not been evaluated. METHODS:Adult MM patients diagnosed between 1973 and 2011 were identified...

journal_title：Cancer

authors： Ailawadhi S,Advani P,Yang D,Ghosh R,Swaika A,Roy V,Foran J,Colon-Otero G,Chanan-Khan A

更新日期：2016-02-15 00:00:00

abstract：BACKGROUND:TRAIL (tumor necrosis factor related apoptosis-inducing ligand) is involved in tumor immune surveillance and, thus, may be a potential cancer therapy. TRAIL expression in the tumor microenvironment has been shown to impact cancer survival in multiple tumor types, including ovarian cancer. We studied TRAIL ex...

journal_title：Cancer

authors： Anees M,Horak P,El-Gazzar A,Susani M,Heinze G,Perco P,Loda M,Lis R,Krainer M,Oh WK

更新日期：2011-03-15 00:00:00

abstract：BACKGROUND:A single-institution, prospective, randomized open trial was performed to compare ondansetron and granisetron in the prevention of chemotherapy-related nausea and vomiting. The effect of antemetic drugs was analyzed indipendently for patients treated with highly emetogenic chemotherapy (Study 1), and those t...

journal_title：Cancer

authors： Gebbia V,Cannata G,Testa A,Curto G,Valenza R,Cipolla C,Latteri MA,Gebbia N

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Increasingly, the quality of life (QOL) of women diagnosed with breast carcinoma is being studied. However, there is little information regarding long term survivors among ethnic minority women. The purpose of this study was to describe the QOL of long term breast carcinoma survivors (BCS) and to examine the...

journal_title：Cancer

authors： Ashing-Giwa K,Ganz PA,Petersen L

更新日期：1999-01-15 00:00:00

abstract：:Intraoperative radiotherapy (IOR) or "direct view" irradiation permits the delivery of a single exposure of high-energy electrons to a surgically exposed tumor. Surgical exposure permits physical retraction of normal uninvolved tissues away from the IOR beam as well as the accurate assessment of the target volume. IOR...

journal_title：Cancer

authors： Goldson AL,Streeter OE Jr,Ashayeri E,Collier-Manning J,Barber JB,Fan KJ

更新日期：1984-12-01 00:00:00

abstract：:We present a case with the unusual association of Graves' disease and functioning pulmonary metastases of follicular thyroid carcinoma. Unlike other reports of thyroid cancer and thyrotoxicosis, this patient's hyperthyroidism was related to a hyperfunctioning primary thyroid neoplasm and not merely to large amounts of...

journal_title：Cancer

authors： Grayzel EF,Bennett B

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:Patients with renal cell carcinoma brain metastases (RCCBM) are frequently excluded from trials and to the authors' knowledge no guidelines currently exist regarding central nervous system (CNS) surveillance or treatment. The objective of the current study was to assist in the creation of treatment guideline...

journal_title：Cancer

authors： Shuch B,La Rochelle JC,Klatte T,Riggs SB,Liu W,Kabbinavar FF,Pantuck AJ,Belldegrun AS

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Melanoma is the most lethal form of skin cancer, with an estimated 68,130 new cases and 8700 deaths in the United States in 2010. The increasing incidence and high death rate associated with metastatic disease support the need to focus on prevention. The authors used data from the Women's Health Initiative (...

journal_title：Cancer

authors： Jagtap D,Rosenberg CA,Martin LW,Pettinger M,Khandekar J,Lane D,Ockene I,Simon MS

更新日期：2012-10-15 00:00:00

abstract：BACKGROUND:Monoclonal antibodies have not been evaluated in metastasizing endocrine tumors, even though these lesions may induce severe morbidity of hormone excess in absence of considerable tumor burden. METHODS:A murine monoclonal antibody of the IgG2a subtype was generated by immunization with dispersed tumor cells...

journal_title：Cancer

authors： Juhlin C,Papanicolaou V,Arnberg H,Klareskog L,Lörelius LE,Rastad J,Oberg K,Akerström G

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Medical records of 50 patients with malignant mesothelioma were reviewed to determine the clinical features and factors influencing survival. METHODS:Charts of all patients whose conditions were diagnosed as malignant mesothelioma were abstracted and analyzed by statistical software. RESULTS:The male-to-fe...

journal_title：Cancer

authors： Sridhar KS,Doria R,Raub WA Jr,Thurer RJ,Saldana M

更新日期：1992-12-15 00:00:00

abstract：BACKGROUND:Intracranial meningiomas are common and comprise 20% of all primary brain tumors. Meningiomas infrequently metastasize; however, to the authors' knowledge there are limited data regarding the spread of disease through cerebrospinal fluid (CSF). METHODS:Eight of 200 consecutive patients (4%) with meningiomas...

journal_title：Cancer

authors： Chamberlain MC,Glantz MJ

更新日期：2005-04-01 00:00:00

abstract：:Because of the rarity of the primary carcinoma of the female urethra, there has been limited experience of individual institutions in management of this disease. Treatment by radiation alone required radium implant skill in early cases and individualized consideration for integrating external and internal irradiation ...

journal_title：Cancer

authors： Prempree T,Wizenberg MJ,Scott RM

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:This retrospective analysis examines the frequency, distribution, and the pattern of disease progression of bone metastasis in patients treated for cervical cancer and the use and results of palliative intent radiation therapy. METHODS:Charts, films, and other available records were reviewed for the 41 pati...

journal_title：Cancer

authors： Ratanatharathorn V,Powers WE,Steverson N,Han I,Ahmad K,Grimm J

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Obesity is considered a risk factor for breast cancer. Modifying life styles that reduce obesity offers the potential for prevention and improved outcomes from cancer. The effects of obesity and breast cancer among African-American women and Hispanic women have been explored in a limited number of studies. T...

journal_title：Cancer

authors： Sarkissyan M,Wu Y,Vadgama JV

更新日期：2011-08-15 00:00:00

abstract：BACKGROUND:Extrapulmonary inflammatory pseudotumor (plasma cell granuloma) is an uncommon lesion in adults and children, and little is known either of its etiology or clinical characteristics. However, it remains a significant source of morbidity to patients and confusion to clinicians. METHODS:Case reports are presen...

journal_title：Cancer

authors： Treissman SP,Gillis DA,Lee CL,Giacomantonio M,Resch L

更新日期：1994-03-01 00:00:00