Intraoperative radiotherapy for intracranial malignancies. A pilot study.

abstract：BACKGROUND:For the current report, the authors examined the characteristic features of morphology and molecular biology of phosphatase and tensin homolog (PTEN), beta-catenin, and p53 immunocytochemistry in endometrial carcinoma by using thin-layer cytologic preparations. METHODS:During a 6-month period, 120 endometri...

journal_title：Cancer

authors： Norimatsu Y,Miyamoto M,Kobayashi TK,Moriya T,Shimizu K,Yanoh K,Tsukayama C,Miyake Y,Ohno E

更新日期：2008-06-25 00:00:00

abstract：:While investigating the cause of mild polycythemia in a young man, a testicular seminoma was discovered with unusual and tumor-dependent features: an absolute polycythemia with high plasma erythropoietin (EPO) levels, an overproduction of estradiol and testosterone, and a dramatic Leydig cell hyperplasia surrounding t...

journal_title：Cancer

authors： Reman O,Reznik Y,Casadevall N,Lacombe C,Troussard X,Mandard JC,Leporrier M,Mahoudeau J

更新日期：1991-11-15 00:00:00

abstract：BACKGROUND:A combination regimen comprised of docetaxel, gemcitabine, and granulocyte-colony stimulating factor (G-CSF) was studied in patients with advanced nonsmall cell lung carcinoma (NSCLC) to determine its antitumor efficacy and tolerance. METHODS:Thirty-four patients with advanced measurable NSCLC (3 patients w...

journal_title：Cancer

authors： Hejna M,Kornek GV,Raderer M,Ulrich-Pur H,Fiebiger WC,Marosi L,Schneeweiss B,Greul R,Scheithauer W

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Diencephalic syndrome (DS) is a complex of signs and symptoms related to hypothalamic dysfunction; its main features are emaciation, despite a normal or slightly diminished caloric intake, and an alert appearance. DS has been almost exclusively described in association with space-occupying lesions of the hyp...

journal_title：Cancer

authors： Perilongo G,Carollo C,Salviati L,Murgia A,Pillon M,Basso G,Gardiman M,Laverda A

更新日期：1997-07-01 00:00:00

abstract：:The treatment for women diagnosed with early breast cancer is complex, dynamic, and controversial. More choices are available for local control and indications for systemic adjuvant therapy have changed dramatically. Knowledge of predictable physical and psychological responses through the various phases of primary tr...

journal_title：Cancer

authors： Knobf MT

更新日期：1990-09-15 00:00:00

abstract：:Various attempts have been made to improve the effectiveness of radiation in the treatment of cerebral malignant astrocytomas. A trend favoring multiple daily fractionated (MDF) radiation therapy over conventional single daily fractionated (CF) radiation therapy was identified in our previous study. In order to assess...

journal_title：Cancer

authors： Shin KH,Urtasun RC,Fulton D,Geggie PH,Tanasichuk H,Thomas H,Muller PJ,Curry B,Mielke B,Johnson E

更新日期：1985-08-15 00:00:00

abstract：:The ultrastructure of three cases of osteoblastoma is described. The osteoblasts resemble normal osteoblasts with a few exceptions: irregular, indented nuclei, and occasional mitochondria with curved cristae and electron-lucent areas. The osteocytes and osteoclasts basically resemble their normal counterparts. There a...

journal_title：Cancer

authors： Steiner GC

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:The purpose of the study was to determine the utility of quantitation of the extracellular domain (ECD) of the HER-2/neu receptor in the serum for predicting response to treatment in patients with primary breast cancer receiving neoadjuvant therapy. METHODS:HER-2/neu ECD was measured in sera obtained from 3...

journal_title：Cancer

authors： Mazouni C,Hall A,Broglio K,Fritsche H,Andre F,Esteva FJ,Hortobagyi GN,Buzdar AU,Pusztai L,Cristofanilli M

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:The staging system for non-small cell lung cancer (NSCLC) does not consider tumor burden or number of metastatic sites, although oligometastases are more favorable. METHODS:Using log-rank testing, the authors analyzed overall survival (OS) in 1284 patients newly presenting with metastatic NSCLC by number of...

journal_title：Cancer

authors： Oh Y,Taylor S,Bekele BN,Debnam JM,Allen PK,Suki D,Sawaya R,Komaki R,Stewart DJ,Karp DD

更新日期：2009-07-01 00:00:00

abstract：:Myelofibrosis occurs in various hematologic neoplasias, including myelodysplastic syndrome (MDS), with a relatively low incidence. To gain insight into the clinical and cytogenetic implications of MDS patients in whom myelofibrosis develops, statistical analysis was done on 82 primary MDS patients with successful cyto...

journal_title：Cancer

authors： Ohyashiki K,Sasao I,Ohyashiki JH,Murakami T,Iwabuchi A,Tauchi T,Saito M,Nakazawa S,Serizawa H,Ebihara Y

更新日期：1991-07-01 00:00:00

abstract：:The use of molecular techniques in cytopathology has become an accepted and billable practice for certain applications. Other applications still are in the developmental or experimental stages but may soon be clinically useful. The current study provides a review of these techniques including molecular detection of cl...

journal_title：Cancer

authors： Rimm DL

更新日期：2000-02-25 00:00:00

abstract：:All patients with a diagnosis of cutaneous malignant melanoma (CMM) in Western Australia from 1980 to 1981 were observed for up to 6 years to determine vital status and to detect the development of local recurrences of the primary lesion. Approximately 35% of all patients had their tumors excised with surgical margins...

journal_title：Cancer

authors： Heenan PJ,English DR,Holman CD,Armstrong BK

更新日期：1992-01-15 00:00:00

abstract：:Doxorubicin is an effective antineoplastic agent, but it frequently causes dose-related cardiotoxic effects. Because the atrial natriuretic peptide (ANP) level is elevated in children with heart defects, the authors measured the ANP levels in children to determine whether ANP might serve as a simple diagnostic indicat...

journal_title：Cancer

authors： Bauch M,Ester A,Kimura B,Victorica BE,Kedar A,Phillips MI

更新日期：1992-03-15 00:00:00

abstract：:A case of granulocytic sarcoma involving the uterine cervix as primary manifestation without evidence of leukemia is presented. It was followed by neurological symptoms 19 months later and a right breast mass 26 months after the initial cervical lesion, but still with no evidence of leukemia. Two years and four months...

journal_title：Cancer

authors： Seo IS,Hull MT,Pak HY

更新日期：1977-12-01 00:00:00

abstract：:The hemoptysis which occurs following lymphography typically consists of one or more episodes of blood-tinged sputum, and generally requires no treatment. In contradistinction to this "mild" form of hemoptysis, the current report describes a case of hemoptysis following lymphography--hemoptysis so severe as to require...

journal_title：Cancer

authors： Marglin SI,Castellino RA

更新日期：1979-02-01 00:00:00

abstract：BACKGROUND:In the United States, incidence rates for malignant tumors of the uterine corpus are lower among blacks than among whites, whereas mortality rates are higher among blacks. Reasons for the higher level of mortality among blacks have been debated. METHODS:Using data from the Surveillance, Epidemiology, and En...

journal_title：Cancer

authors： Sherman ME,Devesa SS

更新日期：2003-07-01 00:00:00

abstract：:Mitomycin C (MMC) has been evaluated in combination with several antitumor agents. Full dose response curves were established for all drugs and drug combinations. Synergy was shown with MMC plus either cyclophosphamide (CYC) or methotrexate (MTX). In testing MMC and CYC against P388 leukemia, the combined treatment yi...

journal_title：Cancer

authors： Mabel JA,Wodinsky I

更新日期：1983-02-15 00:00:00

abstract：BACKGROUND:Hormone replacement therapy (HRT) has proven and presumable benefits for women desiring postmenopausal health preservation. Among HRT-associated risks, the fear of breast carcinoma intimidates women and physicians contemplating hormonal treatment and limits long-term compliance. Identifying effective alterna...

journal_title：Cancer

authors： Diamanti-Kandarakis E,Sykiotis GP,Papavassiliou AG

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Recent clinical trials have documented activity for combinations of chemotherapeutic agents that target the microtubular apparatus in patients with hormone-refractory prostate cancer. Taxol has a novel antimicrotubular mechanism, acting by stabilizing polymerized tubulin. METHODS:Twenty-three patients with ...

journal_title：Cancer

authors： Roth BJ,Yeap BY,Wilding G,Kasimis B,McLeod D,Loehrer PJ

更新日期：1993-10-15 00:00:00

abstract：BACKGROUND:A clinicopathologic evaluation of clinical Stage I and II uterine sarcoma was done by the Gynecologic Oncology Group from 1979-1988. METHODS:After all eligibility criteria were met, 453 cases were evaluable and analyzed for prognostic factors. RESULTS:Of the 301 mixed mesodermal tumors (MMT), 167 were homo...

journal_title：Cancer

authors： Major FJ,Blessing JA,Silverberg SG,Morrow CP,Creasman WT,Currie JL,Yordan E,Brady MF

更新日期：1993-02-15 00:00:00

abstract：:A case of diffuse histiocytic lymphoma with sclerosis and chylous pleural and peritoneal effusions spanning four years from onset to diagnosis is presented. Treatment with combination chemotherapy and consolidative radiotherapy resulted in clinical improvement and the patient remains free of disease 14 months after st...

journal_title：Cancer

authors： Hansen RM,Komaki R,Hanson GA,Schlueter DP,Anderson T

更新日期：1983-06-01 00:00:00

abstract：:Thirty-six patients were evaluated between 1965 and 1983 for glioma of the optic nerves and/or chiasm. Median follow-up was 10.2 years. Pathologic verification was obtained in 32 patients. Tumor initially confined to the optic nerve recurred in one of five patients after complete resection. The actuarial survival for ...

journal_title：Cancer

authors： Flickinger JC,Torres C,Deutsch M

更新日期：1988-02-15 00:00:00

abstract：BACKGROUND:Patients with metachronous multiple colorectal carcinomas have been reported to have a higher frequency of a family history of colorectal carcinoma, associated colorectal adenomas, and extracolonic malignancies. These clinicopathologic factors also are considered to be related to the development of metachron...

journal_title：Cancer

authors： Masubuchi S,Konishi F,Togashi K,Okamoto T,Senba S,Shitoh K,Kashiwagi H,Kanazawa K,Tsukamoto T

更新日期：1999-05-01 00:00:00

abstract：:Neuroendocrine small cell carcinoma is a lethal, but rare, tumor that arises most frequently in the lung. Small cell cancer also rarely may occur in the female genital tract, usually in the cervix. This article concerns the fourth reported case of neuroendocrine small cell carcinoma of the vulva. Previously, small cel...

journal_title：Cancer

authors： Cliby W,Soisson AP,Berchuck A,Clarke-Pearson DL

更新日期：1991-05-01 00:00:00

abstract：:Tn antigen is the immediate precursor of the carcinoma (CA)-associated T antigen; both are masked in non-CA tissues. Tn antigen was detected by absorption of human anti-Tn antibody in 46 of 50 primary breast CAs and in all 6 metastases originating from Tn-positive primary CAs. Thirteen of 25 (52%) anaplastic CAs, but ...

journal_title：Cancer

authors： Springer GF,Taylor CR,Howard DR,Tegtmeyer H,Desai PR,Murthy SM,Felder B,Scanlon EF

更新日期：1985-02-01 00:00:00

abstract：:This study describes the inheritance of a defect in pyrimidine catabolism and its association with drug-induced toxicity in a patient receiving 5-fluorouracil (FUra) as adjuvant chemotherapy for breast carcinoma. The study population included the affected patient (proband), nine of her blood relatives, and seven healt...

journal_title：Cancer

authors： Harris BE,Carpenter JT,Diasio RB

更新日期：1991-08-01 00:00:00

abstract：:Sixty-three gastrectomy specimens (21 with early intestinal type carcinoma, 21 with early diffuse carcinoma, and 21 with benign nonneoplastic lesions) were examined histochemically to determine the distribution of intestinal metaplasia (IM), particularly the sulphomucin-secreting type (Type IIB IM). The frequency and ...

journal_title：Cancer

authors： Matsukuma A,Mori M,Enjoji M

更新日期：1990-08-15 00:00:00

abstract：BACKGROUND:Epidemiologic studies have recently related benzene hexachloride (BHC) to breast carcinoma risk. Experimental studies have also shown that beta-BHC is weakly estrogenic, hence supporting the alleged association. By directly comparing beta-BHC levels in breast adipose tissue from incident breast carcinoma cas...

journal_title：Cancer

authors： Zheng T,Holford TR,Mayne ST,Owens PH,Ward B,Carter D,Dubrow R,Zahm SH,Boyle P,Tessari J

更新日期：1999-05-15 00:00:00

abstract：BACKGROUND:The objective of this study was to determine the clinical characteristics, treatment response, and frequency of p53 overexpression in Ashkenazi Jewish women with hereditary ovarian carcinoma. METHODS:Seventy-one Jewish women with epithelial ovarian carcinoma (EOC) were tested for the three BRCA founder muta...

journal_title：Cancer

authors： Cass I,Baldwin RL,Varkey T,Moslehi R,Narod SA,Karlan BY

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:African-American (AA) women have lower survival rates from cervical cancer compared with white women. The objective of this study was to examine the influence of socioeconomic status (SES) and other variables on racial disparities in overall survival among women with invasive cervical cancer. METHODS:One th...

journal_title：Cancer

authors： Movva S,Noone AM,Banerjee M,Patel DA,Schwartz K,Yee CL,Simon MS

更新日期：2008-03-15 00:00:00