Sulphomucin-secreting intestinal metaplasia in the human gastric mucosa. An association with intestinal-type gastric carcinoma.

Abstract:

:Sixty-three gastrectomy specimens (21 with early intestinal type carcinoma, 21 with early diffuse carcinoma, and 21 with benign nonneoplastic lesions) were examined histochemically to determine the distribution of intestinal metaplasia (IM), particularly the sulphomucin-secreting type (Type IIB IM). The frequency and distribution of Type IIB IM were similar, irrespective of the disease, when age of the patient was matched and if the extension of the IM was similar. Type IIB IM was usually observed in the mucosa along the lesser curvature of the lower portion of the stomach, particularly in elderly patients and was mainly located in the deeper foveolae and intermingled with or transient to those in other types of IM. These findings suggest that a casual relationship between Type IIB IM and intestinal type carcinoma is dubious.

journal_name

Cancer

journal_title

Cancer

authors

Matsukuma A,Mori M,Enjoji M

doi

10.1002/1097-0142(19900815)66:4<689::aid-cncr28206

subject

Has Abstract

pub_date

1990-08-15 00:00:00

pages

689-94

issue

4

eissn

0008-543X

issn

1097-0142

journal_volume

66

pub_type

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