Hepatic veno-occlusive disease due to DTIC.

Abstract:

:A case of fulminant hepatic failure leading to death in a patient receiving DTIC for metastatic melanoma is presented. Autopsy revealed widespread centrilobular necrosis secondary to a veno-occlusive process. There was no evidence of a similar process in other organs, and common causes of similar pathology were ruled out. It is likely that in this patient the hepatic failure was due to DTIC alone. Similar cases have been reported in patients receiving other chemotherapeutic agents. Physicians using these drugs should be aware of this side-effect of therapy, since it is often fatal.

journal_name

Cancer

journal_title

Cancer

authors

Asbury RF,Rosenthal SN,Descalzi ME,Ratcliffe RL,Arseneau JC

doi

10.1002/1097-0142(19800515)45:10<2670::aid-cncr282

subject

Has Abstract

pub_date

1980-05-15 00:00:00

pages

2670-4

issue

10

eissn

0008-543X

issn

1097-0142

journal_volume

45

pub_type

杂志文章

相关文献

CANCER文献大全
  • Aberrant, highly hyperdiploid cells in human papillomavirus-positive, abnormal cytologic samples are associated with progressive lesions of the uterine cervix.

    abstract:BACKGROUND:Infection with oncogenic-type human papillomavirus (HPV) and consecutive cytologic abnormalities of the uterine cervix precede the evolution of carcinoma. However, the specificity of both changes is too low to predict the true malignant potential of the change in a given time point, because the majority of t...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.20848

    authors: Bollmann R,Méhes G,Speich N,Schmitt C,Bollmann M

    更新日期:2005-04-25 00:00:00

  • Treatment of myelodysplastic syndromes with daily oral idarubicin. A phase I-II study.

    abstract:BACKGROUND:Idarubicin, a new anthracycline analogue, is available in an oral preparation, and responses have been observed using relatively aggressive therapy in patients with myelodysplastic syndromes (MDS). The authors studied whether a chronic low-dose schedule would be effective but less myelotoxic. METHODS:Forty-...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(19930315)71:6<1989::aid-cncr2820

    authors: Greenberg BR,Reynolds RD,Charron CB,Squillace KM,Lessin LS,Case DC Jr,Gams RA

    更新日期:1993-03-15 00:00:00

  • Cell-cycle-dependent expression of human melanoma membrane antigen analyzed by flow cytometry.

    abstract::Knowledge of tumor antigenic expression is crucial to the design of therapeutic strategy. A murine monoclonal antibody (BE4) against a human melanoma membrane antigen, was used to study the in vitro expression of this antigen. By membrane immunofluorescence, BE4 reacted against 5 of 8 melanoma lines as compared to zer...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19850315)55:6<1276::aid-cncr2820

    authors: Leong SP,Bolen JL,Chee DO,Smith VR,Taylor JC,Benfield JR,Klevecz RR

    更新日期:1985-03-15 00:00:00

  • Efficacy of imatinib mesylate for the treatment of locally advanced and/or metastatic tenosynovial giant cell tumor/pigmented villonodular synovitis.

    abstract:BACKGROUND:Pigmented villonodular synovitis (PVNS) (also known as diffuse-type giant cell tumor) and tenosynovial giant cell tumors (TGCT) are rare, usually benign neoplasms that affect the synovium and tendon sheaths in young adults. These tumors are driven by the overexpression of colony stimulating factor-1 (CSF1). ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.26409

    authors: Cassier PA,Gelderblom H,Stacchiotti S,Thomas D,Maki RG,Kroep JR,van der Graaf WT,Italiano A,Seddon B,Dômont J,Bompas E,Wagner AJ,Blay JY

    更新日期:2012-03-15 00:00:00

  • Immunologic evaluation of patients with advanced head and neck cancer receiving weekly chemoimmunotherapy.

    abstract::Patients with advanced head and neck cancer have significant reduction in their circulating lymphocyte mass which is reflected in decreased numbers of T cells, Fc receptor cells, and in derangements of T lymphocyte functions, i.e., decreased responsiveness to several dilutions of phytohemagglutinin and lack of develop...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197907)44:1<117::aid-cncr2820440

    authors: Zighelboim J,Dorey F,Parker NH,Calcaterra T,Ward P,Fahey JL

    更新日期:1979-07-01 00:00:00

  • Abnormalities of bone marrow mesenchymal cells in multiple myeloma patients.

    abstract:BACKGROUND:The importance of the bone marrow microenvironment in multiple myeloma is receiving increasing attention. Recent studies have suggested the importance of cytokine production and cell-cell contact by bone marrow stromal cells in the survival of myeloma cells. METHODS:In the current study, the authors examine...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(20010401)91:7<1219::aid-cncr1122

    authors: Wallace SR,Oken MM,Lunetta KL,Panoskaltsis-Mortari A,Masellis AM

    更新日期:2001-04-01 00:00:00

  • Performance measurement in cancer care: uses and challenges.

    abstract::Unnecessary, inappropriate, and futile care are given in all areas of health care including cancer care. Not only does such care increase costs and waste precious resources, but patients may have adverse outcomes when the wrong care is given. One of the ways to address this issue is to measure performance with the use...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19980515)82:10+<2016::aid-

    authors: Lazar GS,Desch CE

    更新日期:1998-05-15 00:00:00

  • Distant nontraumatic clostridial myonecrosis and malignancy.

    abstract::Distant nontraumatic clostridial myonecrosis in association with malignancy is an uncommon disorder, with only 14 well-documented cases previously reported in the English literature. Clostridium perfringens and C. septicum are the most common organisms, usually gaining access to the circulation through an ulcerated le...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19860215)57:4<885::aid-cncr28205

    authors: Kaiser CW,Milgrom ML,Lynch JA

    更新日期:1986-02-15 00:00:00

  • Medulloblastoma. Results of a sequential combined treatment.

    abstract::Actuarial progression-free survival rate at 5 years of a series of 34 patients with medulloblastoma treated by combined surgery, radiotherapy, and chemotherapy was 71%. No relapses were observed in 14 patients followed for more than 5 years. Treatment consisted of a short postoperative course of vincristine (VCR) and ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19841101)54:9<1956::aid-cncr2820

    authors: Bellani FF,Gasparini M,Lombardi F,Zucali R,Luccarelli G,Migliavacca F,Moise S,Nicola G

    更新日期:1984-11-01 00:00:00

  • Prognostic factors for lymphedema after primary treatment of breast carcinoma.

    abstract:BACKGROUND:Lymphedema of the arm is a serious consequence of breast carcinoma treatment. Postmastectomy lymphedema of the upper limb usually is related to certain risk factors such as axillary surgery, radiotherapy, obesity, venous outflow obstruction, delayed wound healing, and infection. The objective of the current ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(20011001)92:7<1783::aid-cncr1694

    authors: Herd-Smith A,Russo A,Muraca MG,Del Turco MR,Cardona G

    更新日期:2001-10-01 00:00:00

  • Malignant mixed tumor of salivary origin: a clinicopathologic study of 146 cases.

    abstract::A 30-year Memorial Hospital experience with 146 patients with malignant mixed tumor is reviewed. These comprised 5% of 2,743 patients who were treated for salivary neoplasms from 1939 through 1968. The tumors arose in the parotid gland in 108 patients, submaxillary gland in 23 patients, mucus or so-called minor saliva...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197702)39:2<388::aid-cncr2820390

    authors: Spiro RH,Huvos AG,Strong EW

    更新日期:1977-02-01 00:00:00

  • Tibial adamantinoma: its histogenesis from ultrastructural studies.

    abstract::Only three previous reports on the ultrastructural appearance of tibial adamantinoma have been found among some 120 cases of this tumor reported in the literature. The tumor in our case is less differentiated than the cases previously reported. We believe it is of epithelial character and the possibilities of its hist...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(197709)40:3<1138::aid-cncr282040

    authors: Yoneyama T,Winter WG,Milsow L

    更新日期:1977-09-01 00:00:00

  • Role of ultrasound-guided fine-needle aspiration of indeterminate and suspicious axillary lymph nodes in the initial staging of breast carcinoma.

    abstract:BACKGROUND:Ultrasound (US) is more sensitive than physical examination alone in determining axillary lymph node involvement during preliminary staging of breast carcinoma. Due to occasional overlap of sonographic features of benign and indeterminate lymph nodes, fine-needle aspiration (FNA) of sonographically indetermi...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/cncr.10786

    authors: Krishnamurthy S,Sneige N,Bedi DG,Edieken BS,Fornage BD,Kuerer HM,Singletary SE,Hunt KK

    更新日期:2002-09-01 00:00:00

  • Intensity-modulated radiotherapy reduces toxicity with similar biochemical control compared with 3-dimensional conformal radiotherapy for prostate cancer: A randomized clinical trial.

    abstract:BACKGROUND:The objective of this article was to report the results from a randomized clinical trial comparing intensity-modulated radiotherapy (IMRT) with 3-dimensonal conformal radiotherapy (3DCRT) for the treatment of prostate cancer on a hypofractionated schedule. METHODS:The authors randomly assigned 215 men who h...

    journal_title:Cancer

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/cncr.29983

    authors: Viani GA,Viana BS,Martin JE,Rossi BT,Zuliani G,Stefano EJ

    更新日期:2016-07-01 00:00:00

  • Spinal cord compression in breast cancer.

    abstract::Myelography was performed on 78 patients with breast cancer who had signs or symptoms compatible with spinal cord compression. Of 42 patients (54%) with extradural defects, 21 (50%) had a complete block. All patients with positive myelograms (M+) had a positive bone scan and 41 of 42 (97%) had positive skeletal x-rays...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19850615)55:12<2839::aid-cncr282

    authors: Harrison KM,Muss HB,Ball MR,McWhorter M,Case D

    更新日期:1985-06-15 00:00:00

  • Background mucosal changes in colorectal carcinomas.

    abstract::The entire colonic mucosa of 51 cases of colorectal carcinoma was examined histologically. Mucosal lesions including goblet cell hyperplasia, crypt dilatation, ulceration with regeneration, basal cell hyperplasia, metaplastic lesions, and adenomas were encountered. Goblet cell hyperplasia (80.4%) was most prominent ad...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Lee YS

    更新日期:1988-04-15 00:00:00

  • Autologous stem cell transplantation for patients with chronic myeloid leukemia. The Argentine Group of Bone Marrow Transplantation (GATMO) experience.

    abstract:BACKGROUND:The objective of this analysis was to evaluate the role of autologous stem cell transplantation (ASCT) in prolonging disease free survival (DFS) and overall survival (OS) in patients with chronic myeloid leukemia (CML) who received autografts of Philadelphia chromosome (Ph) positive or Ph negative cell harve...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.10931

    authors: Koziner B,Dengra C,Lucero G,Klein G,Cánepa C,Milovic V,Milone G,Robinson A,Cerutti I,Saporito G,Kusminsky G,Milone J,Bordone J,Lastiri F,Argentine Group of Bone Marrow Transplantation.

    更新日期:2002-12-01 00:00:00

  • The role of Fas ligand and transforming growth factor beta in tumor progression: molecular mechanisms of immune privilege via Fas-mediated apoptosis and potential targets for cancer therapy.

    abstract::Despite the fact that expression of Fas ligand (FasL) in cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells plays an important role in Fas-mediated tumor killing, During tumor progression FasL-expressing tumor cells are involved in counterattacking to kill tumor-infiltrating lymphocytes (TILs). Soluble Fa...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.20270

    authors: Kim R,Emi M,Tanabe K,Uchida Y,Toge T

    更新日期:2004-06-01 00:00:00

  • Expected population impacts of discontinued prostate-specific antigen screening.

    abstract:BACKGROUND:Prostate-specific antigen (PSA) screening for prostate cancer has high risks of overdiagnosis, particularly among older men, and reports from screening trials indicate that it saves few lives after 11 to 13 years of follow-up. New clinical guidelines recommend against PSA screening for all men or for men age...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.28932

    authors: Gulati R,Tsodikov A,Etzioni R,Hunter-Merrill RA,Gore JL,Mariotto AB,Cooperberg MR

    更新日期:2014-11-15 00:00:00

  • Treatment of acute leukemia in adults.

    abstract::Improvement in the management of acute leukemia in adults has not progressed nearly so rapidly as has the treatment of childhood leukemia. One important difference is that most adults have myeloblastic or related forms of the disease (AML), whereas the majority of children have lymphoblastic leukemia (ALL). However, e...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197508)36:2+<775::aid-cncr282036

    authors: Clarkson BD,Dowling MD,Gee TS,Cunningham IB,Burchenal JH

    更新日期:1975-08-01 00:00:00

  • Acquired Glanzmann's thrombasthenia associated with Hodgkin's lymphoma: a case report and review of the literature.

    abstract:BACKGROUND:Acquired Glanzmann's thrombasthenia is a rare hemorrhagic diathesis resulting from impaired adhesive function of the platelet receptor GPIIb/IIIa (alpha(IIb)beta3). Typically, this disorder develops during adulthood, with patients manifesting fluctuating clinical and laboratory findings. To date, the underly...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/(sici)1097-0142(19980501)82:9<1769::aid-cn

    authors: Malik U,Dutcher JP,Oleksowicz L

    更新日期:1998-05-01 00:00:00

  • AANCART best practices: cancer awareness activities for Seattle's Combodian community.

    abstract::Census data indicate that Cambodian Americans are economically disadvantaged and linguistically isolated. In addition, cancer registry data show that Southeast Asians experience several cancer-related health disparities (e.g., markedly elevated risks of cervical and liver cancer). The Seattle regional Asian American N...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21515

    authors: Seng P,Acorda E,Carey Jackson J,Marchand A,Thai H,Tu SP,Taylor V

    更新日期:2005-12-15 00:00:00

  • Association of very low prostate-specific antigen levels with increased cancer-specific death in men with high-grade prostate cancer.

    abstract:BACKGROUND:The objective of this study was to determine whether a very low presenting prostate-specific antigen (PSA) level was associated with greater prostate cancer-specific mortality (PCSM) among men with a Gleason score (GS) of 8 to 10. METHODS:The Surveillance, Epidemiology, and End Results program was used to i...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.29691

    authors: Mahal BA,Aizer AA,Efstathiou JA,Nguyen PL

    更新日期:2016-01-01 00:00:00

  • The natural history of neoplastic development: the relation of experimental models to human cancer.

    abstract::The natural history of the development of neoplasia in experimental systems may be separated into at least three different stages, those of initiation, promotion and progression. Evidence for such distinct stages has been demonstrated in at least half a dozen different experimental systems. The stage of promotion is t...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820315)49:6<1206::aid-cncr2820

    authors: Pitot HC

    更新日期:1982-03-15 00:00:00

  • COMB (cyclophosphamide, oncovin, methyl-CCNU, and bleomycin): a four-drug combination in solid tumors.

    abstract::One hundred eighty-nine patients received a four-drug combination consisting of cyclophosphamide, Oncovin (vincristine), methyl CCNU, and bleomycin (COMB), according to three different drug regimens, performed sequentially. Of the 189, 62 had a partial response (33%) including 11/33 with squamous lung cancer, 11/32 wi...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197508)36:2<327::aid-cncr2820360

    authors: Livingston RB,Einhorn LH,Bodey GP,Burgess MA,Freireich EJ,Gottlieb JA

    更新日期:1975-08-01 00:00:00

  • Serum p53 antibody is a useful tumor marker in superficial esophageal squamous cell carcinoma.

    abstract:BACKGROUND:Patients with superficial (mucosal or submucosal) esophageal carcinoma (SEC) have significantly better survival rates than patients with advanced carcinoma. Some patients with advanced esophageal carcinoma have been reported to test positive for serum p53 antibodies (Abs). Because very few patients with supe...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Shimada H,Takeda A,Arima M,Okazumi S,Matsubara H,Nabeya Y,Funami Y,Hayashi H,Gunji Y,Suzuki T,Kobayashi S,Ochiai T

    更新日期:2000-10-15 00:00:00

  • Pelvic computed tomography of breast carcinoma patients. Should it routinely be added to abdominal computed tomography?

    abstract:BACKGROUND:This study was conducted to determine if pelvic computed tomography (CT) should routinely be appended to abdominal CT in the workup of patients with breast carcinoma. METHODS:The abdominal-pelvic CTs of 139 breast carcinoma patients (195 exams) were reviewed. Scans were grouped by indication and whether pel...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Meyer JI,Herts BR,Einstein DM,Singer AA,Budd GT,Cohen MA

    更新日期:1997-02-01 00:00:00

  • DNCB reactivity and prognosis in 419 patients with malignant melanoma.

    abstract::Delayed cutaneous hypersensitivity to 2,3-dinitrochlorobenzene (DNCB) was tested in 419 patients with malignant melanoma to determine whether DNCB reactivity was associated with prognosis. At the time of definitive surgery, a positive DNCB test was seen in 82% of the patients in State I (regional lymph node histologic...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810515)47:10<2446::aid-cncr282

    authors: Camacho ES,Pinsky CM,Braun DW Jr,Golbey RB,Fortner JG,Wanebo HJ,Oettgen HF

    更新日期:1981-05-15 00:00:00

  • Ascertainment of postprostatectomy radiotherapy for prostate cancer in the Surveillance, Epidemiology, and End Results database.

    abstract:BACKGROUND:Surveillance, Epidemiology, and End Results (SEER) data are frequently used to examine receipt of adjuvant radiotherapy (RT), but to the authors' knowledge the accuracy of data regarding second-course treatments is unknown. METHODS:Using SEER-Medicare-linked data, the authors identified a cohort of men who ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.30154

    authors: Wang K,Sheets NC,Basak R,Chen RC

    更新日期:2016-10-01 00:00:00

  • Prognostic factors after hepatectomy for hepatocellular carcinomas. A univariate and multivariate analysis.

    abstract::The current study determines the prognostic factors after hepatectomy for hepatocellular carcinomas. The 295 patients who underwent hepatectomy from 1973 through 1987 were included for a univariate and a Cox multivariate analysis. The favoring conditions were determined as follows. The essential requirements are (1) t...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19900301)65:5<1104::aid-cncr2820

    authors: Yamanaka N,Okamoto E,Toyosaka A,Mitunobu M,Fujihara S,Kato T,Fujimoto J,Oriyama T,Furukawa K,Kawamura E

    更新日期:1990-03-01 00:00:00