Urinary cholesterol. VII. The significance of the excretion of nonesterified cholesterol in patients with uterine carcinomas.

abstract：BACKGROUND:Recently, invasion of vascular spaces by endometrial carcinoma has received particular attention as a prognostic factor. The goal of the current investigation was to re-examine the effect of vascular invasion on tumor recurrence and survival in patients with endometrial carcinoma. METHODS:Surgical specimens...

journal_title：Cancer

authors： Inoue Y,Obata K,Abe K,Ohmura G,Doh K,Yoshioka T,Hoshiai H,Noda K

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:The objective of this study was to evaluate the long-term survival and late toxicities of concurrent-adjuvant chemotherapy in patients with stage III through IVB nasopharyngeal carcinoma (NPC) from endemic regions of China. METHODS:Patients with stage III to IVB NPC were assigned randomly to receive radioth...

journal_title：Cancer

authors： Chen Y,Sun Y,Liang SB,Zong JF,Li WF,Chen M,Chen L,Mao YP,Tang LL,Guo Y,Lin AH,Liu MZ,Ma J

更新日期：2013-06-15 00:00:00

abstract：BACKGROUND:Previous investigators have detected shifts to lower stages at diagnosis for renal cell carcinoma and prostate cancer. The authors investigated whether a similar pattern is seen for urothelial carcinomas of the bladder, ureter, and renal pelvis and sought to identify changes in cancer grade and survival tren...

journal_title：Cancer

authors： David KA,Mallin K,Milowsky MI,Ritchey J,Carroll PR,Nanus DM

更新日期：2009-04-01 00:00:00

abstract：:Central nervous system (CNS) recurrence continues to be a significant complication in the treatment of adult patients with acute lymphoblastic leukemia (ALL). Preventing CNS recurrence has been a therapeutic challenge and has not been addressed critically in many clinical trials. Adult studies modeled on childhood ALL...

journal_title：Cancer

authors： Jabbour E,Thomas D,Cortes J,Kantarjian HM,O'Brien S

更新日期：2010-05-15 00:00:00

abstract：BACKGROUND:There is global variation in the onset of hepatocellular carcinoma (HCC). The objective of the current study was to investigate the impact of country of birth on age at the time of HCC diagnosis in the United States. METHODS:Incident HCC cases diagnosed between 2000 and 2012 in the Surveillance, Epidemiolog...

journal_title：Cancer

authors： Yang JD,Altekruse SF,Nguyen MH,Gores GJ,Roberts LR

更新日期：2017-01-01 00:00:00

abstract：:This report describes 11 adults with non-Hodgkin's lymphoma who presented with symptoms caused by large mediastinal masses. Patients with lymphoblastic lymphoma were excluded from this analysis. Most of the patients were young women with localized disease at presentation. Ten tumors were diffuse large cell ("histiocyt...

journal_title：Cancer

authors： Trump DL,Mann RB

更新日期：1982-07-15 00:00:00

abstract：BACKGROUND:The expression of vascular endothelial growth factor (VEGF)-A isoforms (121, 165, 189, 206), VEGF-B, VEGF-C and VEGF-D in both experimental and clinical models of head and neck squamous cell carcinoma (HNSCC) was determined and correlated with conventional clinicopathologic parameters, with particular refere...

journal_title：Cancer

authors： O-charoenrat P,Rhys-Evans P,Eccles SA

更新日期：2001-08-01 00:00:00

abstract：:Pituitary adenomas rarely are metastatic. Extracranial visceral metastases of prolactinomas were not previously reported. The authors report a case of a 34-year-old man with a prolactin-producing pituitary carcinoma and histologically proven lung metastases. Pathologic examination of the pulmonary spread included elec...

journal_title：Cancer

authors： Atienza DM,Vigersky RJ,Lack EE,Carriaga M,Rusnock EJ,Tsou E,Cerrone F,Kattah JG,Sausville EA

更新日期：1991-10-01 00:00:00

abstract：:Studies of calcium metabolism in 38 patients with cancer indicated that: 1) intestinal absorption of calcium was reduced in patients with skeletal metastases and in those with hypercalcemia; 2) calcium-47 space (a measurement of bone turnover rate) was high in the patients with skeletal metastases; 3) hypercalcemic pa...

journal_title：Cancer

authors： Coombes RS,Ward MK,Greenberg PB,Hillyard CJ,Tulloch BR,Morrison R,Joplin GF

更新日期：1976-11-01 00:00:00

abstract：:Human prostate specimens from 25 patients provided 15 normal, four benign prostatic hypertrophy (BPH), and seven adenocarcinoma samples which were studied using a polyclonal antibody against prostatic specific antigen (PSA) and protein A-gold complex. Our study showed the presence of gold particles in cytoplasmic vesi...

journal_title：Cancer

authors： Sinha AA,Wilson MJ,Gleason DF

更新日期：1987-09-15 00:00:00

abstract：BACKGROUND:Receipt of chemotherapy at the end of life (EOL) is considered an indicator of poor quality of care for medical oncology. The objective of this study was to characterize the use of radiotherapy (RT) in patients with nonsmall cell lung cancer (NSCLC) during the same period. METHODS:Treatment characteristics ...

journal_title：Cancer

authors： Kapadia NS,Mamet R,Zornosa C,Niland JC,D'Amico TA,Hayman JA

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Approximately 5-10% of patients with rhabdomyosarcomas (RMS) are diagnosed during the first year of life, and their clinical characteristics have been well documented. However, because RMS rarely occurs during the neonatal period, little is known about neonatal RMS. METHODS:Four patients with neonatal RMS w...

journal_title：Cancer

authors： Rodriguez-Galindo C,Hill DA,Onyekwere O,Pin N,Rao BN,Hoffer FA,Kun LE,Pappo AS,Santana VM

更新日期：2001-09-15 00:00:00

abstract：:To see whether urine enzyme activities could be used as an index in evaluating the disease status of leukemia patients, we examined the activities of four enzymes: arylsulfatases A(AS-A) and B(AS-B), alkaline phosphatase (AP), and lactate dehydrogenase (LDH). AP and LDH showed no consistent patterns. The activities of...

journal_title：Cancer

authors： Posey LE,Rainey J,Vial R,Ryan D,Bickers JH,Morgan LR Jr,Samuels MS,Hull EW

更新日期：1979-09-01 00:00:00

abstract：:The German Society of Pediatric Oncology in 1981 initiated the Cooperative Ewing's Sarcoma Study (CESS 81) using a four-drug combination of chemotherapy prior to definitive local control with surgery and/or radiation. From January 1, 1981 until February 28, 1985, 93 patients were registered at the trial office from 54...

journal_title：Cancer

authors： Jürgens H,Exner U,Gadner H,Harms D,Michaelis J,Sauer R,Treuner J,Voûte T,Winkelmann W,Winkler K

更新日期：1988-01-01 00:00:00

abstract：:Data are now available from two randomized trials showing that adjuvant irradiation of the internal mammary and supraclavicular nodes following a radical or modified radical mastectomy results in increased survival rates. A retrospective analysis of 1111 patients treated at M. D. Anderson Hospital with radical mastect...

journal_title：Cancer

authors： Montague ED,Fletcher GH

更新日期：1980-08-15 00:00:00

abstract：:Over the last decade, new cytotoxic treatments and targeted therapies have altered treatment paradigms for patients with metastatic non-small cell lung cancer (NSCLC). We sought to analyze the impact of histology and biomarker selection criteria on outcomes of clinical trials in metastatic NSCLC reported over the last...

journal_title：Cancer

authors： Gentzler RD,Yentz SE,Johnson ML,Rademaker AW,Patel JD

更新日期：2014-12-15 00:00:00

abstract：BACKGROUND:The bone destruction in myeloma patients is largely responsible for the clinical features of the disease. However, only recently has attention focused on identifying and developing drugs targeted specifically at the osteolysis. Receptor activator of NF-kappaB ligand (RANKL), macrophage inflammatory protein (...

journal_title：Cancer

authors： Oyajobi BO,Mundy GR

更新日期：2003-02-01 00:00:00

abstract：:The authors report an analysis of 47 leukemia patients (including 9 from our own medical center) whose courses were complicated by 48 episodes of clostridial septicemia. There were 36 adults and 11 children; acute myelogenous leukemia and acute lymphoblastic leukemia accounted for 61.7% and 14.9% of cases, respectivel...

journal_title：Cancer

authors： Caya JG,Farmer SG,Ritch PS,Wollenberg NJ,Tieu TM,Oechler HW,Spivey M

更新日期：1986-05-15 00:00:00

abstract：:Among the patients showing evidence of cerebral metastases without previously known cancer history, lung cancer has been found 37 times as the primary tumor in our institution. There were 34 men and three women and all but two were heavy smokers. Only one presented at diagnosis with thoracic symptoms but the chest rad...

journal_title：Cancer

authors： Trillet V,Catajar JF,Croisile B,Turjman F,Aimard G,Bourrat C,Bret P,Carrie C,Chassard JL,Chauvin F

更新日期：1991-06-01 00:00:00

abstract：:Three hundred fifteen radioisotopic bone scans ranging from initial scan only to nine scans per patient, performed on 114 patients with adenocarcinoma of the prostate between 1979 and 1984, were reviewed. Seventeen patients had positive scans, ten on initial scan and seven at follow-up. Nine patients had bone pain at ...

journal_title：Cancer

authors： Corrie D,Timmons JH,Bauman JM,Thompson IM

更新日期：1988-06-15 00:00:00

abstract：BACKGROUND:Sialyl-Tn (STn) represents an aberrantly glycosylated mucin epitope that is expressed in breast carcinoma and other adenocarcinomas and is an important factor in the development of novel immunotherapeutic approaches. The primary aim of the current study was to investigate the influence of STn expression on t...

journal_title：Cancer

authors： Kinney AY,Sahin A,Vernon SW,Frankowski RF,Annegers JF,Hortobagyi GN,Buzdar AU,Frye DK,Dhingra K

更新日期：1997-12-15 00:00:00

abstract：:The present overview of advanced prostate cancer required the identification of randomized clinical trials studying the question of maximal androgen blockade versus the classic castration therapy. The heterogeneity of the trials concerned the type of castration (surgical or chemical) and the type of antiandrogen (flut...

journal_title：Cancer

authors： Suciu S,Sylvester R,Iversen P,Christensen I,Denis L

更新日期：1993-12-15 00:00:00

abstract：:Survivors of pediatric and young adult cancers remain at risk for subsequent diseases, including those related to human papillomavirus (HPV) infection. Prevention of HPV acquisition through vaccination has become possible over the last decade. HPV vaccines have been shown to be safe and effective, yet rates of vaccina...

journal_title：Cancer

authors： Temkin SM,Seibel NL

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:The observed seasonal and geographic variations in the incidence of immunoproliferative small intestinal disease (IPSID) suggest that environmental factors contribute to its pathogenesis. One such environmental factor, the Epstein-Barr virus (EBV), has been associated with other B-cell lymphoproliferative di...

journal_title：Cancer

authors： Baddoura FK,Unger ER,Mufarrij A,Nassar VH,Zaki SR

更新日期：1994-09-15 00:00:00

abstract：:As the federal government struggles to meet ever-growing budgetary constraints, the need for research into the causes of and potential therapies for treating cancer demands the urgent attention of Congressional leaders. This will require innovative, cost-effective approaches to address the unique needs of cancer resea...

journal_title：Cancer

authors： Mack C

更新日期：1993-11-01 00:00:00

abstract：:Thin-needle aspiration biopsy (TNAB) was performed on 22 patients with orbital tumors. Nine patients were studied before the introduction of computed tomography (CT) and only two cytologic diagnoses could be established. Thirteen aspiration biopsies guided by CT were successful. The technique of the CT-guided TNAB of ...

journal_title：Cancer

authors： Czerniak B,Woyke S,Daniel B,Krzysztolik Z,Koss LG

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:The influence of HER-2/neu on prognosis of breast cancer is controversial. The authors investigated by immunohistochemistry in node-positive disease the influence of the pattern of immunostaining (membranous or cytoplasmic) on outcome and the prognostic significance of this marker in patients receiving or no...

journal_title：Cancer

authors： Têtu B,Brisson J

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Patients with chronic lymphocytic leukemia (CLL) that transforms to Richter syndrome (RS) frequently show atypical lymphocytes in bone marrow; however, a diagnosis of RS requires confirmation of the presence of sheets of large cells in bone marrow or lymph nodes. METHODS:In this study, the authors evaluated...

journal_title：Cancer

authors： Ma Y,Mansour A,Bekele BN,Zhou X,Keating MJ,O'Brien S,Giles FJ,Albitar M

更新日期：2004-05-15 00:00:00

abstract：:In the evaluation of cervical cancer, computed tomography (CT) is used primarily to stage advanced tumors and evaluate for recurrence. Because of reports that CT imaging lacks sensitivity and specificity in the detection of primary tumors and metastatic lesions, its use in these applications has been limited, but rece...

journal_title：Cancer

authors： Pannu HK,Fishman EK

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:The authors have noted that in cervical cytology specimens from perimenopausal and postmenopausal women, the diagnosis of atypical squamous cells of undetermined significance (ASC-US), as defined in the Bethesda system, is often not associated with a clinically evident lesion on follow-up. Reflex human papil...

journal_title：Cancer

authors： Johnston EI,Logani S

更新日期：2007-06-25 00:00:00