The curative value of irradiation in the treatment of nondisseminated breast cancer.

Abstract:

:Data are now available from two randomized trials showing that adjuvant irradiation of the internal mammary and supraclavicular nodes following a radical or modified radical mastectomy results in increased survival rates. A retrospective analysis of 1111 patients treated at M. D. Anderson Hospital with radical mastectomies with and without irradiation to the peripheral lymphatic areas shows equal ten-year survival rates in irradiated and unirradiated patients in spite of the fact that the irradiated patients had a much higher incidence of histologically positive nodes. There is a significant percentage of patients surviving ten-years in 353 patients with locally or regionally advanced tumors treated with simple mastectomy and irradiation without chemotherapy. Radiation of gross local and regional recurrences has a high risk of failure and radiation sequelae.

journal_name

Cancer

journal_title

Cancer

authors

Montague ED,Fletcher GH

doi

10.1002/1097-0142(19800815)46:4+<995::aid-cncr2820

subject

Has Abstract

pub_date

1980-08-15 00:00:00

pages

995-8

issue

4 Suppl

eissn

0008-543X

issn

1097-0142

journal_volume

46

pub_type

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