Acute lymphoblastic leukemia in adults and children. Differences in response with similar therapeutic regimens.

abstract：:The role of palliative radiation treatment of prostate cancer is well recognized. Appreciation of the value of definitive radiation therapy in management of locally advanced prostate cancer is increasing. Optimal management requires careful patient selection with multidiscipline evaluation to provide accurate grading ...

journal_title：Cancer

authors： Taylor WJ

更新日期：1977-02-01 00:00:00

abstract：:To investigate the possible implications of heterogeneity among the non-Hodgkin's lymphomas for bone marrow purging using complement-fixing monoclonal antibodies to lymphoma-associated antigens, a panel of large cell lymphoma cell lines of diverse phenotypes was treated with monoclonal antibodies DLC-48 and LN-1. An a...

journal_title：Cancer

authors： Winter JN,Marder RJ,Mankad B,Epstein AL

更新日期：1988-03-15 00:00:00

abstract：:Over the last 20 to 30 years, a recognition and general acceptance of the entity of malignant fibrous histiocytoma and monophasic synovial sarcoma has occurred. The introduction of these diagnostic categories among the generic group of spindle cell sarcomas now requires a reevaluation of the more traditional and histo...

journal_title：Cancer

authors： Scott SM,Reiman HM,Pritchard DJ,Ilstrup DM

更新日期：1989-08-15 00:00:00

abstract：BACKGROUND:Angiosarcoma is rare, and information about its clinical features are limited. Therefore, a large scale study of angiosarcoma was performed in Japan. METHODS:Through a nationwide Japanese study, 99 cases of angiosarcoma were collected and their clinicopathologic findings were summarized relative to predispo...

journal_title：Cancer

authors： Naka N,Ohsawa M,Tomita Y,Kanno H,Uchida A,Aozasa K

更新日期：1995-02-15 00:00:00

abstract：BACKGROUND:Amplification of DNA in certain chromosomal regions plays a crucial role in the development and progression of human malignancies, specifically when protooncogenic target genes within those amplicons are overexpressed. Comparative genomic hybridization studies have revealed frequent amplification at 20q in p...

journal_title：Cancer

authors： Zhao C,Yasui K,Lee CJ,Kurioka H,Hosokawa Y,Oka T,Inazawa J

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:The current study was performed to describe patient characteristics, treatment patterns, survival, health care resource use (HRU), and costs among older women in the United States with advanced (American Joint Committee on Cancer stage III/IV) triple-negative breast cancer (TNBC) in the Surveillance, Epidemi...

journal_title：Cancer

authors： Schwartz KL,Simon MS,Bylsma LC,Ruterbusch JJ,Beebe-Dimmer JL,Schultz NM,Flanders SC,Barlev A,Fryzek JP,Quek RGW

更新日期：2018-05-15 00:00:00

abstract：:The current study determines the prognostic factors after hepatectomy for hepatocellular carcinomas. The 295 patients who underwent hepatectomy from 1973 through 1987 were included for a univariate and a Cox multivariate analysis. The favoring conditions were determined as follows. The essential requirements are (1) t...

journal_title：Cancer

authors： Yamanaka N,Okamoto E,Toyosaka A,Mitunobu M,Fujihara S,Kato T,Fujimoto J,Oriyama T,Furukawa K,Kawamura E

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Telomerase is commonly recognized as an effective anticancer target. The human telomerase reverse transcriptase (hTERT), the rate-limiting component of telomerase, is expressed in most malignant tumors, but it is not found in most normal somatic cells. Here, we report a real-time and noninvasive method to mo...

journal_title：Cancer

authors： Yu ST,Li C,Lü MH,Liang GP,Li N,Tang XD,Wu YY,Shi CM,Chen L,Li CZ,Cao YL,Fang DC,Yang SM

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Although cancer has become one of the leading health burdens, to the authors' knowledge, evidence regarding its relationship with a healthy lifestyle in the Chinese population remains limited. METHODS:The authors evaluated the association between clustering of healthy lifestyle factors and cancer risk using...

journal_title：Cancer

authors： Wang X,Yang X,Li J,Liu F,Chen J,Liu X,Cao J,Shen C,Yu L,Lu F,Wu X,Zhao L,Wu X,Li Y,Hu D,Huang J,Lu X,Gu D

更新日期：2019-06-15 00:00:00

abstract：:Laparoscopy is highly effective in diagnosing malignant liver disease, with overall accuracy in the 90% range. Up to 80% of the liver surface can be inspected, and biopsies can be directed with precision. A major advantage over scan guided percutaneous techniques is the ability to detect and biopsy lesions only a few ...

journal_title：Cancer

authors： Lightdale CJ

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to present planning, feasibility, toxicity, and outcome of helical tomotherapy for spinal cord-sparing reirradiation of spinal metastases and tumors. METHODS:Thirty-six patients with spinal metastases and tumors who had undergone previous radiotherapy were reirradiated with hel...

journal_title：Cancer

authors： Sterzing F,Hauswald H,Uhl M,Herm H,Wiener A,Herfarth K,Debus J,Krempien R

更新日期：2010-08-15 00:00:00

abstract：BACKGROUND:It is important for clinicians, researchers, and others who shape public health policy to understand the demographic correlates and psychologic factors that drive health behaviors, such as screening for early detection of cancer, particularly among individuals at high risk for developing the disease. METHOD...

journal_title：Cancer

authors： Beebe-Dimmer JL,Wood DP Jr,Gruber SB,Chilson DM,Zuhlke KA,Claeys GB,Cooney KA

更新日期：2004-04-01 00:00:00

abstract：BACKGROUND:: Although platinum-based combinations are considered the best option of care for patients with advanced nonsmall cell lung cancer (NSCLC), single-agent therapy is the preferred treatment for older patients. Since the late 1990s, various combinations of third-generation agents (gemcitabine [G], vinorelbine, ...

journal_title：Cancer

authors： Russo A,Rizzo S,Fulfaro F,Adamo V,Santini D,Vincenzi B,Gebbia N,Carreca I

更新日期：2009-05-01 00:00:00

abstract：:One hundred and sixty-two cases of Stage IA microinvasive carcinoma of the cervix are presented. These patients represent the combined experience at the University of Miami School of Medicine, Miami, Florida, and Downstate Medical Center, Brooklyn, New York. The criteria used in both institutions are 1) penetration of...

journal_title：Cancer

authors： Averette HE,Nelson JH Jr,Ng AB,Hoskins WJ,Boyce JG,Ford JH Jr

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND:Radiologic Diagnostic Oncology Group 5 is a multicenter clinical trial designed to evaluate fine-needle aspiration (FNA) of nonpalpable breast lesions performed by multiple operators using the same protocol. METHODS:Four hundred and nineteen women with mammographically detected nonpalpable breast lesions we...

journal_title：Cancer

authors： Pisano ED,Fajardo LL,Tsimikas J,Sneige N,Frable WJ,Gatsonis CA,Evans WP,Tocino I,McNeil BJ

更新日期：1998-02-15 00:00:00

abstract：BACKGROUND:The aim was to determine the long-term outcome for patients with FIGO stage IV epithelial ovarian carcinoma (EOC) treated with intraperitoneal (IP) chemotherapy after second-look assessment. METHODS:By using data from a retrospective cohort of 433 patients who received IP therapy after second-look assessmen...

journal_title：Cancer

authors： Zivanovic O,Barakat RR,Sabbatini PJ,Brown CL,Konner JA,Aghajanian CA,Abu-Rustum NR,Levine DA

更新日期：2008-06-15 00:00:00

abstract：BACKGROUND:Pretreatment serum prostate specific antigen (PSA) level is a powerful prognostic factor for clinically localized prostate carcinoma. The traditional prognostic factors, T classification and Gleason score, appear to have been relegated to a minor position. This study was conducted to evaluate the relative pr...

journal_title：Cancer

authors： Zagars GK,Pollack A,von Eschenbach AC

更新日期：1997-04-01 00:00:00

abstract：:Five hundred and sixty-six patients with either Stage III or IV Hodgkin's disease were prospectively randomized to test whether CCNU and/or vinblastine are more effective than mechlorethamine and/or vincristine with procarbazine and prednisone. The combination of CCNU, vinblastine, procarbazine, and prednisone (CVPP) ...

journal_title：Cancer

authors： Cooper MR,Pajak TF,Nissen NI,Stutzman L,Brunner K,Cuttner J,Falkson G,Grunwald H,Bank A,Leone L,Seligman BR,Silver RT,Weiss RB,Haurani F,Blom J,Spurr CL,Glidewell OJ,Gottlieb AJ,Holland JF

更新日期：1980-08-15 00:00:00

abstract：BACKGROUND:It is frequently difficult to establish histologically whether a parathyroid tumor is a parathyroid carcinoma, parathyromatosis, or an atypical adenoma. The authors asked whether these tumors have a distinctive molecular profile, whether benign tumors could be distinguished from malignant tumors, and whether...

journal_title：Cancer

authors： Fernandez-Ranvier GG,Khanafshar E,Tacha D,Wong M,Kebebew E,Duh QY,Clark OH

更新日期：2009-01-15 00:00:00

abstract：BACKGROUND:The current study was conducted to evaluate the Patient-Reported Outcomes Measurement Information System Depression Short Form (PROMIS-D-SF) as a screening measure for young adult cancer survivors (YACS) compared with a structured diagnostic interview. METHODS:A total of 249 YACS (aged 18-40 years) complete...

journal_title：Cancer

authors： Recklitis CJ,Blackmon JE,Chang G

更新日期：2020-04-01 00:00:00

abstract：:Fifty-four patients with advanced squamous, large-cell or adeno-carcinoma of the lung were treated with a three drug regimen of high-dose cisplatin, vindesine and a four-day bleomycin infusion (CVB). All patients had measurable disease; none had previously received chemotherapy. Of 52 patients evaluable for response, ...

journal_title：Cancer

authors： Itri LM,Gralla RJ,Kelsen DP,Chapman RA,Casper ES,Braun DW Jr,Howard JE,Golbey R,Heelan RT

更新日期：1983-03-15 00:00:00

abstract：BACKGROUND:Although almost half of all incidents of breast carcinoma occur in women age > or = 65 years, not enough is known about appropriate care for patients in this age group. The objective of the current study was to evaluate the role of breast conservation therapy in the management of breast carcinoma in women ag...

journal_title：Cancer

authors： Vlastos G,Mirza NQ,Meric F,Hunt KK,Kuerer HM,Ames FC,Ross MI,Buchholz TA,Hortobagyi GN,Singletary SE

更新日期：2001-09-01 00:00:00

abstract：:The authors have performed a clinical and statistical analysis of the presenting features of adult acute leukemia classified according to the French-American-British (FAB) hematopathologic criteria. Observations were made on 70 variables of history, physical examination, and laboratory examination recorded for 195 pat...

journal_title：Cancer

authors： Burns CP,Armitage JO,Frey AL,Dick FR,Jordan JE,Woolson RF

更新日期：1981-05-15 00:00:00

abstract：:During the past decade, one of the major changes in the field of oncology has been in the surgical approach to primary and secondary cancer of the liver. As a result of data and experience gained in liver transplantation programs and with the application of vascular surgical principles, resectability rates have been i...

journal_title：Cancer

authors： Fortner JG,MacLean BJ,Kim DK,Howland WS,Turnbull AD,Goldiner P,Carlon G,Beattie EJ Jr

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:Nonsteroidal antiinflammatory drugs (NSAIDs) inhibit the development of lung tumors in experimental animals. To the authors' knowledge there are little data regarding whether regular use of NSAIDs reduces the risk of developing lung carcinoma in humans. METHODS:The association between lung carcinoma risk an...

journal_title：Cancer

authors： Muscat JE,Chen SQ,Richie JP Jr,Altorki NK,Citron M,Olson S,Neugut AI,Stellman SD

更新日期：2003-04-01 00:00:00

abstract：:The most important area in which cancer care and bioethics intersect is in the care of the dying. It is in the shift toward according more control to patients, more choice in the setting in which death will come, and in the willingness to take palliative care and comfort care seriously that bioethics has most usefully...

journal_title：Cancer

authors： Caplan AL

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:The long-term impact of breast carcinoma and its treatment was assessed in 153 breast carcinoma survivors previously treated on a Phase III randomized trial (Cancer and Leukemia Group B [CALGB 7581]) a median of 20 years after entry to CALGB 7581. METHODS:Survivors were interviewed by telephone using the fo...

journal_title：Cancer

authors： Kornblith AB,Herndon JE 2nd,Weiss RB,Zhang C,Zuckerman EL,Rosenberg S,Mertz M,Payne D,Jane Massie M,Holland JF,Wingate P,Norton L,Holland JC

更新日期：2003-08-15 00:00:00

abstract：:A 65-year-old woman had pancytopenia, splenomegaly, and an inaspirable bone marrow. Diagnostic evaluation demonstrated that she had both leukemic reticuloendotheliosis (LRE), or hairy cell leukemia, and an additional lympho-reticular neoplasm, most likely a "histiocytic" lymphoma. The diagnosis of LRE was based on the...

journal_title：Cancer

authors： Adler SS,Shetty J,Golomb HM

更新日期：1979-05-01 00:00:00

abstract：:A retrospective study is reported of 120 consecutive cases of patients presenting with brain metastases as the primary sign of their malignancy. Primary site was found in 62 patients (53 while alive and 9 at postmortem examination) and remained unknown in 58. Lung was the most frequent primary site (45% of known sites...

journal_title：Cancer

authors： Le Chevalier T,Smith FP,Caille P,Constans JP,Rouesse JG

更新日期：1985-08-15 00:00:00

abstract：BACKGROUND:The purine analogs pentostatin and cladribine have revolutionized the treatment of hairy cell leukemia (HCL) with overall responses in greater than 85% of patients and a median progression-free survival of up to 15 years. They continue to be effective at second- and even third-line therapy; however, alternat...

journal_title：Cancer

authors： Else M,Osuji N,Forconi F,Dearden C,Del Giudice I,Matutes E,Wotherspoon A,Lauria F,Catovsky D

更新日期：2007-11-15 00:00:00