Radiation oncology: cancer of the prostate.

abstract：BACKGROUND:A proposed pathologic (pTNM) classification system for prostate carcinoma was analyzed for its impact on survival outcome in the prostate specific antigen (PSA) era. The impact of margin status on the survival outcome of patients with otherwise organ-confined disease (i.e., without extraprostatic extension o...

journal_title：Cancer

authors： Blute ML,Bostwick DG,Seay TM,Martin SK,Slezak JM,Bergstralh EJ,Zincke H

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:We sought to determine the impact of radical nephrectomy case volume, hospital size, and geographic region on immediate surgical outcomes for patients undergoing radical nephrectomy in academic centers across the country. METHODS:The University HealthSystem Consortium (UHC) Clinical Data Base was queried fo...

journal_title：Cancer

authors： Mitchell RE,Lee BT,Cookson MS,Barocas DA,Duke Herrell S,Clark PE,Smith JA,Chang SS

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Examination was performed on pathologic material from patients enrolled in the National Surgical Adjuvant Breast Project (NSABP) protocol B-18, in which the clinical effects of preoperative (preop) and postoperative (postop) doxorubicin and cyclophosphamide (AC) were compared. METHODS:Of the total number of...

journal_title：Cancer

authors： Fisher ER,Wang J,Bryant J,Fisher B,Mamounas E,Wolmark N

更新日期：2002-08-15 00:00:00

abstract：:The American Joint Committee on Cancer proposes the following criteria for evaluating putative prognostic factors: they must be (1) significant, (2) independent, and (3) clinically important. Furthermore, we suggest the criteria for selecting a prognostic system that includes TNM and new prognostic factors. These crit...

journal_title：Cancer

authors： Burke HB,Henson DE

更新日期：1993-11-15 00:00:00

abstract：BACKGROUND:This Phase III trial was performed to compare the roles of oral etoposide and intravenous (i.v.) vinblastine in the treatment of Mediterranean Kaposi's Sarcoma (MEKS) in elderly patients with severe disease (Stages II, Ac/B, III, and IV). PATIENTS AND METHODS:Sixty-five patients were randomized to receive e...

journal_title：Cancer

authors： Brambilla L,Labianca R,Boneschi V,Fossati S,Dallavalle G,Finzi AF,Luporini G

更新日期：1994-11-15 00:00:00

abstract：:Plasma CEA concentration before and after administration of secretin and cholecystokinin-pancreozymin has been determined in 89 patients with neoplastic or inflammatory pancreatric disease and other neoplastic and nonneoplastic disorders. The purpose of the study was to expore the specificity and sensitivity of such a...

journal_title：Cancer

authors： Lindstedt G,Lundberg PA,Rolny P

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND:Optimal treatments for vulvar and vaginal melanomas (VVMs) have not been identified. Herein, the authors compare molecular profiles between VVM and nongynecologic melanoma (NGM) subtypes with the objective of identifying novel, targetable biomarkers. METHODS:In total, 2304 samples of malignant melanoma that...

journal_title：Cancer

authors： Hou JY,Baptiste C,Hombalegowda RB,Tergas AI,Feldman R,Jones NL,Chatterjee-Paer S,Bus-Kwolfski A,Wright JD,Burke WM

更新日期：2017-04-15 00:00:00

abstract：BACKGROUND:Bisphosphonates currently are the most important class of antiresorptive agents used in the treatment of metabolic bone diseases, including tumor-associated osteolysis and hypercalcemia, Paget's disease, and osteoporosis. These compounds have high affinity for calcium and therefore target to bone mineral, wh...

journal_title：Cancer

authors： Rogers MJ,Gordon S,Benford HL,Coxon FP,Luckman SP,Monkkonen J,Frith JC

更新日期：2000-06-15 00:00:00

abstract：BACKGROUND:It has been shown that adoptive immunotherapy with Epstein-Barr virus (EBV)-specific cytotoxic T-lymphocytes (CTL) is effective for the treatment of EBV-induced lymphoproliferative disease in stem cell transplantation recipients and organ transplantation recipients. The role of EBV CTL in other tumors for wh...

journal_title：Cancer

authors： Lucas KG,Salzman D,Garcia A,Sun Q

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Cisplatin has been reported to enhance the cell-killing effect of radiation. The current study was conducted to evaluate the efficacy and toxicity of radiotherapy combined with cisplatin in patients with locally advanced pancreatic carcinoma. METHODS:Forty-one patients with pancreatic carcinoma that was unr...

journal_title：Cancer

authors： Okusaka T,Okada S,Tokuuye K,Wakasugi H,Saisho H,Ishikawa O,Matsuno S,Sato T,Sato K,Non-surgical Treatment Group for Pancreatic Cancer in Japan.

更新日期：2001-04-01 00:00:00

abstract：:Greatest surface diameter of a cancer, together with suspicion of regional node metastasis, forms the basis for prognosis through the clinical TNM staging system for many cancers. In oral cancer, however, surface size sometimes fails to correlate, or sometimes inversely correlates, with tumor aggressiveness. To shed l...

journal_title：Cancer

authors： Moore C,Flynn MB,Greenberg RA

更新日期：1986-07-01 00:00:00

abstract：:The possible effect of oral contraceptive (OC) use on the prognosis of established breast cancer was investigated in 154 young women aged 35 and younger. No significant differences were found between the study group of 59 OC users, and the control group of 95 nonusers in age, parity and gravidity, family history of br...

journal_title：Cancer

authors： Rosner D,Lane WW,Perez Brett R

更新日期：1985-04-01 00:00:00

abstract：:The results of trials testing combined surgery and chemotherapy in lung cancer are reviewed. Fifteen adjuvant trials using various chemotherapeutic agents were analyzed to determine reasons for their lack of success. Current trials with adjuvant therapy in lung cancer are briefly outlined. In addition, analysis of the...

journal_title：Cancer

authors： Legha SS,Muggia FM,Carter SK

更新日期：1977-04-01 00:00:00

abstract：BACKGROUND:The association between hormone replacement therapy (HRT) and a reduced lung cancer risk has been reported in previous studies. There is a high female to male ratio in Chinese lung cancer patients, and female patients have different clinicopathological characteristics compared with Western patient population...

journal_title：Cancer

authors： Chen KY,Hsiao CF,Chang GC,Tsai YH,Su WC,Perng RP,Huang MS,Hsiung CA,Chen CJ,Yang PC,GEFLAC Study Group.

更新日期：2007-10-15 00:00:00

abstract：:This study examines the interrelationships of depth of penetration, tumor size, and the number of positive nodes in Dukes C colorectal cancer. The results indicated that depth of tumor penetration was related to both tumor size and the number of positive regional lymph nodes. Tumors with positive nodes which failed to...

journal_title：Cancer

authors： Wolmark N,Fisher ER,Wieand HS,Fisher B

更新日期：1984-06-15 00:00:00

abstract：:Sarcoma of the breast represents less than 1% of primary mammary malignancies; this study reports 25 such cases. The largest group had malignant fibrous histiocytoma (44%), followed by liposarcoma (24%) and fibrosarcoma (16%). Also represented were clear cell sarcoma, neurogenic sarcoma, leiomyosarcoma, and alveolar s...

journal_title：Cancer

authors： Pollard SG,Marks PV,Temple LN,Thompson HH

更新日期：1990-09-01 00:00:00

abstract：:Interleukin (IL)-2 therapy leads to respiratory dysfunction due to increased vascular permeability. This study examines the role of the chemoattractant, immunomodulator, and permeability-promoting agent leukotriene (LT) B4 in this setting. Sheep with chronic lung lymph fistulae were given IL-2, 10(5) U/kg as an IV bol...

journal_title：Cancer

authors： Klausner JM,Goldman G,Skornick Y,Valeri R,Inbar M,Shepro D,Hechtman HB

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) complicating cirrhosis has a high intrahepatic recurrence rate after treatment by surgical resection or percutaneous ethanol injection (PEI). In this study, certain clinical, biochemical, and pathologic parameters were evaluated as risk factors for intrahepatic tumor recurrence...

journal_title：Cancer

authors： Pompili M,Rapaccini GL,de Luca F,Caturelli E,Astone A,Siena DA,Villani MR,Grattagliano A,Cedrone A,Gasbarrini G

更新日期：1997-04-15 00:00:00

abstract：:The etiology of cancer resembles that of many other diseases in that multiple factors may be required. Because of this, the role or viruses in the etiology of human cancers is especially difficult to assess. When animal tumor systems were used as models, the roles of various predisposing characteristics in virus oncog...

journal_title：Cancer

authors： Rapp F,Reed CL

更新日期：1977-07-01 00:00:00

abstract：:Estradiol and testosterone levels in the peripheral and ovarian circulation of patients with endometrial cancer and of postmenopausal women were studied. These levels proved to be the same in the two groups. The ovaries of neither group secreted estradiol. The testosterone level in the ovarian circulation of all exami...

journal_title：Cancer

authors： Schenker JG,Weinstein D,Okon E

更新日期：1979-11-01 00:00:00

abstract：BACKGROUND:The growth of cancer symptom management research has been limited by challenges of slow recruitment and under-enrollment. One potential solution to this problem is the use of screening questions that identify patients who are interested in participating in research. The goal of this study was to evaluate thi...

journal_title：Cancer

authors： Crowley R,Casarett D

更新日期：2003-05-01 00:00:00

abstract：:Aggregates of cells resembling those of cutaneous nevi have been found in the capsules of lymph nodes. Although seemingly rare, this extraordinary lesion could conceivably occur often enough to be more than a pathological curiosity, and should be differentiated from metastatic tumor. Slides from every axillary lymph n...

journal_title：Cancer

authors： Ridolfi RL,Rosen PP,Thaler H

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:The incidence of basal cell carcinoma (BCC) in a defined population is unknown. METHODS:The incidence of histologically diagnosed cases of BCC in a defined population of a city in southern Sweden was studied. Four 2-year periods were examined from 1970 to 1986. Cases from 1970 and 1980 were reexamined micro...

journal_title：Cancer

authors： Dahl E,Aberg M,Rausing A,Rausing EL

更新日期：1992-07-01 00:00:00

abstract：:The frequency and significance of hyperprolactinemia was studied in 21 consecutive, untreated male patients with bronchogenic carcinoma. Seven patients (33%) were found to have elevated serum prolactin (hPRL) levels. No correlation was demonstrated between increased hPRL levels, tissue histology, or tumor burden. L-do...

journal_title：Cancer

authors： Davis S,Proper S,May PB,Ertel NH

更新日期：1979-08-01 00:00:00

abstract：:The activity of the alpha interferons against AIDS-related Kaposi's sarcoma (KS) has been demonstrated in numerous clinical trials. Unfortunately, most reports have involved small patient cohorts and a variety of dosages and schedules of administration. We report here a series of Phase II trials with interferon alfa-2...

journal_title：Cancer

authors： Volberding PA,Mitsuyasu RT,Golando JP,Spiegel RJ

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Inactivation of the tumor suppressor gene PTEN/MMAC1/TEP1, located on chromosome 10q23, is a common event in advanced stages of diverse human malignancies. However, the prognostic role of PTEN expression in patients with hepatocellular carcinoma (HCC) has not been characterized. METHODS:One hundred five res...

journal_title：Cancer

authors： Hu TH,Huang CC,Lin PR,Chang HW,Ger LP,Lin YW,Changchien CS,Lee CM,Tai MH

更新日期：2003-04-15 00:00:00

abstract：:Fifty-one cases of acinic cell carcinoma (ACC) arising in major and minor salivary glands are reported (primary sites: parotid 37, submandibular, six, and oral cavity, eight.) These lesions usually produced painless slowly growing masses. Of 49 patients with follow-up information, 17 (35%) developed local recurrences ...

journal_title：Cancer

authors： Perzin KH,LiVolsi VA

更新日期：1979-10-01 00:00:00

abstract：:The greatest decrease in breast cancer mortality is likely to derive from applying globally existing therapies at an earlier stage. A high priority of the World Health Organization (WHO) cancer control program is the outreach approach that promotes worldwide access to cancer therapies of proven values. Therefore, the ...

journal_title：Cancer

authors： Koroltchouk V,Stanley K,Stjernswärd J

更新日期：1990-06-15 00:00:00

abstract：:Merkel cell carcinoma (MCC) is a relatively rare cutaneous malignancy that occurs predominantly in the older white population. The incidence of MCC appears to have tripled during the past 20 years; an increase that is likely to continue because of the growing number of older Americans. The pathogenesis of MCC remains ...

journal_title：Cancer

authors： Bichakjian CK,Lowe L,Lao CD,Sandler HM,Bradford CR,Johnson TM,Wong SL

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Biomarker-guided clinical trials are increasingly common in metastatic urothelial carcinoma (mUC), yet patients for whom contemporary tumor tissue is not available are not eligible. Technological advancements in sequencing have made cell-free circulating DNA (cfDNA) next-generation sequencing (NGS) readily a...

journal_title：Cancer

authors： Agarwal N,Pal SK,Hahn AW,Nussenzveig RH,Pond GR,Gupta SV,Wang J,Bilen MA,Naik G,Ghatalia P,Hoimes CJ,Gopalakrishnan D,Barata PC,Drakaki A,Faltas BM,Kiedrowski LA,Lanman RB,Nagy RJ,Vogelzang NJ,Boucher KM,Vaishampa

更新日期：2018-05-15 00:00:00