Characterization of metastatic urothelial carcinoma via comprehensive genomic profiling of circulating tumor DNA.

abstract：BACKGROUND:The objective of the current study was to correlate pretreatment computed tomography and magnetic resonance imaging studies with outcomes for patients with squamous or basal cell carcinoma of the skin and clinical perineural invasion. METHODS:Between 1986 and 2002, 45 patients were treated with radiotherapy...

journal_title：Cancer

authors： Galloway TJ,Morris CG,Mancuso AA,Amdur RJ,Mendenhall WM

更新日期：2005-03-15 00:00:00

abstract：BACKGROUND:Although cutaneous desmoplastic malignant melanoma (DMM) has been well characterized, those arising from the oral mucosa have been less well defined. METHODS:We evaluated the clinical and pathologic features of three patients with biopsy-proven DMM examined at the North Carolina Baptist Hospital. Routine he...

journal_title：Cancer

authors： Kilpatrick SE,White WL,Browne JD

更新日期：1996-08-01 00:00:00

abstract：:The platinum-free interval is the most important predictive factor of a response to subsequent lines of chemotherapy and the most important prognostic factor for progression-free and overall survival in patients with recurrent epithelial ovarian cancer. A nonplatinum regimen is generally considered the most appropriat...

journal_title：Cancer

authors： Tomao F,D'Incalci M,Biagioli E,Peccatori FA,Colombo N

更新日期：2017-09-15 00:00:00

abstract：:Deguelin is a rotenoid compound that exists in abundant quantities in the bark, roots, and leaves of the Leguminosae family of plants. An analysis of evidence from both in vitro and in vivo studies suggests that deguelin displays potent anticancer activity against multiple cancer types and exhibits chemopreventive pot...

journal_title：Cancer

authors： Varughese RS,Lam WS,Marican AABH,Viganeshwari SH,Bhave AS,Syn NL,Wang J,Wong AL,Kumar AP,Lobie PE,Lee SC,Sethi G,Goh BC,Wang L

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Systemic, high-dose interferon-alpha treatment given three times per week subcutaneously induces tumor regression in approximately 30% of patients with inoperable hepatocellular carcinoma (HCC). The objective of the current study was to determine the efficacy and safety of transcatheter arterial interferon e...

journal_title：Cancer

authors： Yuen MF,Ooi CG,Hui CK,Wong WM,Wong BC,Chan AO,Lai CL

更新日期：2003-06-01 00:00:00

abstract：:Nickel-related cancers of the respiratory tract have been recognized for nearly 50 years and represent a unique opportunity for prevention among refinery workers. Studies of exposed employees have been conducted in which evaluations were made of the histopathologic changes in the respiratory mucosa and the body burden...

journal_title：Cancer

authors： Barton RT,Hogetveit AC

更新日期：1980-06-15 00:00:00

abstract：BACKGROUND:The objective of the current study was to examine the impact of adherence to guidelines on stage-specific survival outcomes in patients with stage III and high-risk stage II colon cancer. The National Comprehensive Cancer Network (NCCN) has established working, expert consensus, and evidence-based guidelines...

journal_title：Cancer

authors： Boland GM,Chang GJ,Haynes AB,Chiang YJ,Chagpar R,Xing Y,Hu CY,Feig BW,You YN,Cormier JN

更新日期：2013-04-15 00:00:00

abstract：:Variation in response rates to chemotherapy and survival in patients with hepatic metastases from colorectal carcinoma may be due to patient selection factors. The prognostic importance of 13 factors were analyzed in 112 patients with only hepatic metastases, who were eligible for hepatic artery infusional chemotherap...

journal_title：Cancer

authors： Kemeny N,Niedzwiecki D,Shurgot B,Oderman P

更新日期：1989-02-15 00:00:00

abstract：:From 1975 until 1984 37 children with newly diagnosed Hodgkin's disease were treated with six mechlorethamine, vincristine, procarbazine, and prednisone (MOPP) courses with or without involved field radiotherapy (25 Gy) independent of the stage of their disease. Patients with small lymph node tumors (less than 4 cm) r...

journal_title：Cancer

authors： Behrendt H,Van Bunningen BN,Van Leeuwen EF

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND:To assess whether the effectiveness of a combination of transcatheter arterial chemoembolization (TACE) and percutaneous ethanol injection (PEI) is superior to PEI alone in the treatment of patients with small hepatocellular carcinoma (HCC), a randomized controlled study was performed. METHODS:Fifty-two pat...

journal_title：Cancer

authors： Koda M,Murawaki Y,Mitsuda A,Oyama K,Okamoto K,Idobe Y,Suou T,Kawasaki H

更新日期：2001-09-15 00:00:00

abstract：:The objective of this study was to evaluate the sensitivity of two methods for determining bone marrow involvement with non-Hodgkin's lymphoma. These methods were histologic review of bone marrow aspirates, and clot sections versus in vitro growth of lymphoma colonies on soft agar. Forty-two bone marrow aspirates were...

journal_title：Cancer

authors： Smith SD,Kisker S,Bush L,Trueworthy RC

更新日期：1984-04-15 00:00:00

abstract：:Hereditary adenomatosis of the colon and rectum (HACR) is associated with a wide variety of extracolonic manifestations. Two cases of neoplasia involving the adrenal gland are reported, one adenoma and one carcinoma. The literature relating these lesions to HACR and other syndromes of malignant and nonmalignant growth...

journal_title：Cancer

authors： Painter TA,Jagelman DG

更新日期：1985-05-01 00:00:00

abstract：:Four patients with benign giant cell tumor and one patient with probable benign giant cell tumor associated with Paget's disease of bone are reported. The familial and geographic clustering of these cases is unique in that three patients were related and all patients traced ancestral roots to the same area of southern...

journal_title：Cancer

authors： Jacobs TP,Michelsen J,Polay JS,D'Adamo AC,Canfield RE

更新日期：1979-08-01 00:00:00

abstract：:An infant who presented with a thigh mass and coagulopathy was found to have a hemangioendothelioma. The tumor rapidly enlarged despite accepted therapeutic modalities, and the child died after a sudden cardiac arrest. Postmortem examination revealed a highly invasive tumor mass that had infiltrated the bowel and invo...

journal_title：Cancer

authors： Weinblatt ME,Kahn E,Kochen JA

更新日期：1984-11-15 00:00:00

abstract：BACKGROUND:Lung carcinoma remains the major cause of cancer death in North America and is even more common among military veterans. The objective of this study was to determine whether there were differences in the characteristics and survival of Pennsylvania patients with lung carcinoma in the Veterans Administration ...

journal_title：Cancer

authors： Campling BG,Hwang WT,Zhang J,Thompson S,Litzky LA,Vachani A,Rosen IM,Algazy KM

更新日期：2005-08-15 00:00:00

abstract：:The authors retrospectively reviewed 50 episodes of spinal epidural tumor that occurred in 42 patients with metastatic prostate cancer and were treated with external-beam radiation. Treatment response was evaluated in terms of symptoms, neurologic status, and, in most cases, reduction of tumor on repeat myelography. A...

journal_title：Cancer

authors： Zelefsky MJ,Scher HI,Krol G,Portenoy RK,Leibel SA,Fuks ZY

更新日期：1992-11-01 00:00:00

abstract：:Previous studies have shown that magnetic resonance imaging (MRI) is sensitive to white matter changes in children receiving cranial radiation of 3000 cGy or greater. The current study used MRI to investigate the integrity of white matter in children receiving 1800 to 2400 cGy of cranial radiation. Ten survivors of ac...

journal_title：Cancer

authors： Kramer JH,Norman D,Brant-Zawadzki M,Ablin A,Moore IM

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated an association between a diagnosis of cancer and the risk of suicide; however, they failed to account for psychiatric care before a cancer diagnosis, which may confound this relationship. The objective of this study was to assess the effect of a cancer diagnosis on the risk...

journal_title：Cancer

authors： Klaassen Z,Wallis CJD,Chandrasekar T,Goldberg H,Sayyid RK,Williams SB,Moses KA,Terris MK,Nam RK,Urbach D,Austin PC,Kurdyak P,Kulkarni GS

更新日期：2019-08-15 00:00:00

abstract：:Data from 133 patients with cancer and suspected compression of the spinal cord or cauda equina was reviewed. Although there were differences in presenting symptoms and signs between the group of 62 patients with compression and the 71 without, no single symptom or sign discriminated adequately between the two groups....

journal_title：Cancer

authors： Bernat JL,Greenberg ER,Barrett J

更新日期：1983-05-15 00:00:00

abstract：:The authors have performed a clinical and statistical analysis of the presenting features of adult acute leukemia classified according to the French-American-British (FAB) hematopathologic criteria. Observations were made on 70 variables of history, physical examination, and laboratory examination recorded for 195 pat...

journal_title：Cancer

authors： Burns CP,Armitage JO,Frey AL,Dick FR,Jordan JE,Woolson RF

更新日期：1981-05-15 00:00:00

abstract：BACKGROUND:The development of new chelating agents and radiolabeling protocols is essential to progress in radioimmunotherapy with antibody-chelate conjugates. METHODS:Immunoconjugates of four polyazamacrocycles with N-bonded acetate groups were prepared by conjugation via 2-iminothiolane to Lym-1, a murine antilympho...

journal_title：Cancer

authors： Kukis DL,Diril H,Greiner DP,DeNardo SJ,DeNardo GL,Salako QA,Meares CF

更新日期：1994-02-01 00:00:00

abstract：:The serial technetium 99 (99Tc) bone scans of 76 patients with Stage D-2 prostate cancers were reviewed. Sites of metastases in skeletal areas in decreasing order were vertebrae, ribs, pelvis, long bones, and skull. Patients with one or two involved skeletal areas had a significantly longer progression-free interval a...

journal_title：Cancer

authors： Knudson G,Grinis G,Lopez-Majano V,Sansi P,Targonski P,Rubenstein M,Sharifi R,Guinan P

更新日期：1991-07-15 00:00:00

abstract：:Malignant schwannomas with rhabdomyoblastic differentiation have been termed malignant "Triton" tumors (MTT). To define the natural history of MTT, we have analyzed our experience (9 cases, the largest series reported) in combination with the 27 previously described in the literature (total 36 cases). This study was i...

journal_title：Cancer

authors： Brooks JS,Freeman M,Enterline HT

更新日期：1985-06-01 00:00:00

abstract：:Postmenopausal patients with metastatic breast cancer were treated with medroxyprogesterone acetate (MPA) (Clinovir) in dosages between 500 and 1500 mg orally per day. The relation of MPA plasma concentrations and endocrine effects were studied in a longitudinal fashion. MPA exerted suppressive effects on the basal an...

journal_title：Cancer

authors： Blossey HC,Wander HE,Koebberling J,Nagel GA

更新日期：1984-09-15 00:00:00

abstract：BACKGROUND:Gene expression profiling (GEP) has been rapidly adopted for early breast cancer and can aid in chemotherapy decision making. Study results regarding racial disparities in testing are conflicting, and may reflect different care settings. To the authors' knowledge, data regarding the influence of provider fac...

journal_title：Cancer

authors： Reeder-Hayes KE,Wheeler SB,Baggett CD,Zhou X,Meng K,Roberts MC,Carey LA,Meyer AM

更新日期：2018-04-15 00:00:00

abstract：:Only three previous reports on the ultrastructural appearance of tibial adamantinoma have been found among some 120 cases of this tumor reported in the literature. The tumor in our case is less differentiated than the cases previously reported. We believe it is of epithelial character and the possibilities of its hist...

journal_title：Cancer

authors： Yoneyama T,Winter WG,Milsow L

更新日期：1977-09-01 00:00:00

abstract：BACKGROUND:Uterine serous carcinoma (USC) is not recognized as part of any defined hereditary cancer syndrome, and its association with hereditary breast and ovarian carcinoma and Lynch syndrome are uncertain. METHODS:Using targeted capture and massively parallel genomic sequencing, 151 subjects with USC were assessed...

journal_title：Cancer

authors： Pennington KP,Walsh T,Lee M,Pennil C,Novetsky AP,Agnew KJ,Thornton A,Garcia R,Mutch D,King MC,Goodfellow P,Swisher EM

更新日期：2013-01-15 00:00:00

abstract：:Fourteen patients with 16 metastatic ostogenic sarcoma lesions were treated with high-dose methotrexate (HDMTX) with citrovorum factor rescue (CFR), adriamycin, and pulse high-dose cyclophosphamide combined with radiation therapy. Thirteen of 16 lesions responded. Responses consisted of relief of pain (6/6 patients) i...

journal_title：Cancer

authors： Rosen G,Tefft M,Martinez A,Cham W,Murphy ML

更新日期：1975-03-01 00:00:00

abstract：:The clinical diagnosis of lymphangitic carcinomatosis of the lung has generally been confirmed by open lung or transthoracic needle biopsy, precedures with significant morbidity and mortality, particularly in patients with respiratory insufficiency. We present six cases of lymphangitic carcinomatosis diagnosed by tran...

journal_title：Cancer

authors： Aranda C,Sidhu G,Sasso LA,Adams FV

更新日期：1978-10-01 00:00:00

abstract：:Of 209 Hodgkin's disease patients treated at least 6 months with a five-drug combination of induction chemotherapy and having a complete remission, four patients developed acute myelogenous leukemia (AML) as a second malignant neoplasm. The overall relative risk for development of AML is 185.0 (P less than 0.05) and t...

journal_title：Cancer

authors： Bartolucci AA,Liu C,Durant JR,Gams RA

更新日期：1983-12-15 00:00:00