Cancer and bioethics: caring and consensus.

abstract：:Nine years after biopsy and radiation therapy for an extramedullary plasmacytoma of the nasal cavity, a 64-year-old man developed locally recurrent tumor. Repeat biopsy revealed tumor identical in hematoxylin and eosin stain (H & E) appearance to that found originally, leading to the diagnosis of recurrent extramedull...

journal_title：Cancer

authors： Abrams RA,Wilson JF,Komorowski RA,Collins D,Toohill RJ

更新日期：1987-07-01 00:00:00

abstract：:Long-term survival of 1986 consecutive patients with infiltrating duct carcinoma of the breast treated at the National Cancer Institute of Milano (Italy) in two periods of time (1971 to 1972 and 1977 to 1978) was comparatively evaluated to verify if the evolving concepts in the management of breast cancer had an impac...

journal_title：Cancer

authors： Cascinelli N,Greco M,Morabito A,Bufalino R,Testori A,Baldini MT,Andreola S,Leo E,Galluzzo D,Rilke F

更新日期：1991-07-15 00:00:00

abstract：BACKGROUND:Alveolar soft part sarcoma (ASPS), chondrosarcoma (CS), chordoma, epithelioid sarcoma, and solitary fibrous tumor (SFT) are malignant tumors that are relatively resistant to chemotherapy and for which more effective drug therapy is needed. METHODS:The 5 listed subtypes were enrolled into a single indolent s...

journal_title：Cancer

authors： Schuetze SM,Bolejack V,Choy E,Ganjoo KN,Staddon AP,Chow WA,Tawbi HA,Samuels BL,Patel SR,von Mehren M,D'Amato G,Leu KM,Loeb DM,Forscher CA,Milhem MM,Rushing DA,Lucas DR,Chugh R,Reinke DK,Baker LH

更新日期：2017-01-01 00:00:00

abstract：:Urinary polyamine concentrations in 91 samples were assayed in 79 patients with malignant melanoma who were classified as to clinical stage, as well as to activity of disease. Patients with active disease had higher mean polyamine values, increased frequency of polyamine elevations, and increased frequency of two or m...

journal_title：Cancer

authors： Townsend RM,Banda PW,Marton LJ

更新日期：1976-11-01 00:00:00

abstract：:Retinitis pigmentosa, a hereditary disease characterized by progressive retinal degeneration and blindness, has been associated with numerous diseases. We report the first association between retinitis pigmentosa and colon cancer in 3 of 53 hospitalized patients with retinitis pigmentosa at the Massachusetts General H...

journal_title：Cancer

authors： Winzelberg GG,Greenstein R,Ferrucci JT Jr

更新日期：1980-06-01 00:00:00

abstract：:Giant cell tumors of synovium (pigmented villonodular synovitis) involving the vertebral column recently have been seen in two women: the third and fourth cases to be reported in the English-language literature. Unlike the previously reported cases, both these tumors grew outside the dura and produced symptoms of spin...

journal_title：Cancer

authors： Weidner N,Challa VR,Bonsib SM,Davis CH Jr,Carrol TJ Jr

更新日期：1986-05-15 00:00:00

abstract：BACKGROUND:Two types of correction for absorbed dose (D) estimates are described for clinical applications of internal emitters. The first is appropriate for legal and scientific reasons involving phantom-based estimates; the second is patient-specific and primarily intended for radioimmunotherapy (RIT). METHODS:The M...

journal_title：Cancer

authors： Williams LE,Liu A,Yamauchi DM,Lopatin G,Raubitschek AA,Wong JY

更新日期：2002-02-15 00:00:00

abstract：BACKGROUND:During the last two decades, a rising incidence of adenocarcinoma of the esophagus has been observed in the Western world. The prognostic relevance of tumor-biological factors, such as DNA ploidy or c-erbB-2 overexpression, for overall survival following complete resection is still unknown. METHODS:In a ret...

journal_title：Cancer

authors： Nakamura T,Nekarda H,Hoelscher AH,Bollschweiler E,Harbeck N,Becker K,Siewert JR,Harbec N corrected to Harbeck N

更新日期：1994-04-01 00:00:00

abstract：:Results of remission induction therapy in refractory acute nonlymphocytic leukemia (ANLL) has been improved since the introduction of high-dose cytosine arabinoside. However, the toxicity of these regimens attributes to an early death rate of about 20% to 30%. The authors treated 37 poor-risk patients with ANLL with i...

journal_title：Cancer

authors： Dekker AW,Nieuwenhuis HK,Verdonck LF

更新日期：1990-05-01 00:00:00

abstract：:The metabolism of 5-fluorouracil (5-FU) was studied in biopsy specimens of primary colorectal cancer and healthy colonic mucosa obtained from previously untreated patients immediately after surgical removal. The conversion of 5-FU to anabolites was measured under saturating substrate (5-FU) and cosubstrate concentrati...

journal_title：Cancer

authors： Peters GJ,van Groeningen CJ,Laurensse EJ,Pinedo HM

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:In many areas of health care, whether patients receive specific medical interventions often is influenced heavily by the local availability of resources for delivering those services. However, relations between resource availability and utilization are relatively unexplored in cancer care, including perioper...

journal_title：Cancer

authors： Wong SL,Wei Y,Birkmeyer JD

更新日期：2007-02-15 00:00:00

abstract：:Despite proven benefits of neoadjuvant chemotherapy in patients with locally advanced, invasive breast cancer, no regimen is recommended as the treatment of choice. Neoadjuvant chemotherapy regimens encompass single-agent and combination therapy and sequential treatment. For this report, the author reviewed the litera...

journal_title：Cancer

authors： Buzdar AU

更新日期：2007-12-01 00:00:00

abstract：:The pancreatographic appearance and the clinical presentation of ten patients presenting with adenocarcinoma of the head of the pancreas coexisting with chronic pancreatitis were compared with those of 45 patients with chronic pancreatitis (CP), without malignancy, investigated at the same time period. All ten patient...

journal_title：Cancer

authors： Shemesh E,Czerniak A,Nass S,Klein E

更新日期：1990-02-15 00:00:00

abstract：:Although clinically evident thyroid carcinoma is not a frequent neoplasm (incidence 2.7 per 100,000 persons in La Plata, Argentina), occult carcinomas are present in a high proportion of the population, but there are marked differences along geographical lines. The purpose of the present study is to establish the prev...

journal_title：Cancer

authors： Ottino A,Pianzola HM,Castelletto RH

更新日期：1989-07-15 00:00:00

abstract：BACKGROUND:Cytotoxic analogs of somatostatin (SST), such as AN-238, which consists of 2-pyrrolinodoxorubicin (AN-201) linked to the SST carrier RC-121, can be targeted to tumors that express SST receptors. Because SST receptors are present in ovarian carcinoma cells, the authors evaluated the effect of AN-238 on the UC...

journal_title：Cancer

authors： Plonowski A,Schally AV,Koppan M,Nagy A,Arencibia JM,Csernus B,Halmos G

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to analyze the extent of hypoxia in prostate carcinoma tumors using the Eppendorf pO(2) microelectrode and correlate this with pretreatment characteristics and prognostic factors. METHODS:Custom-made Eppendorf pO(2) microelectrodes were used to obtain pO(2) measurements from th...

journal_title：Cancer

authors： Movsas B,Chapman JD,Greenberg RE,Hanlon AL,Horwitz EM,Pinover WH,Stobbe C,Hanks GE

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Primary small cell carcinoma arising in organs other than the lung were thought to be relatively rare. However, with the increasing technical sophistication of pathology departments, tumors with foci of small cell neuroendocrine components are being identified more frequently. The pattern of disease involvem...

journal_title：Cancer

authors： Lyster MT,Kies MS,Kuzel TM

更新日期：1994-12-15 00:00:00

abstract：BACKGROUND:The authors investigated the putative surrogate endpoints of best response, complete response (CR), confirmed response, and progression-free survival (PFS) for associations with overall survival (OS), and as possible surrogate endpoints for OS. METHODS:Individual patient data from 870 untreated extensive st...

journal_title：Cancer

authors： Foster NR,Qi Y,Shi Q,Krook JE,Kugler JW,Jett JR,Molina JR,Schild SE,Adjei AA,Mandrekar SJ

更新日期：2011-03-15 00:00:00

abstract：:Mesenchymal chondrosarcoma of bone and soft tissues treated at the Istituto Ortopedico Rizzoli are reviewed. The skeletal locations were prominent in five cases. Only two cases were in the soft tissues. Radiographic picture in the bone shows an aggressive osteolysis, with soft tissues invasion. Histologic picture is t...

journal_title：Cancer

authors： Bertoni F,Picci P,Bacchini P,Capanna R,Innao V,Bacci G,Campanacci M

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:US breast cancer mortality is declining, but thousands of women still die each year. METHODS:Two established simulation models examine 6 strategies that include increased screening and/or treatment or elimination of obesity versus continuation of current patterns. The models use common national data on inci...

journal_title：Cancer

authors： Mandelblatt J,van Ravesteyn N,Schechter C,Chang Y,Huang AT,Near AM,de Koning H,Jemal A

更新日期：2013-07-15 00:00:00

abstract：BACKGROUND:Differentiating primary glandular from high-grade squamous intraepithelial lesions (HSIL) that involve endocervical glands is not an uncommon diagnostic problem in liquid-based gynecological cytology. Squamous and atypical glandular cell lesions may show similar cytomorphologic features. The aim of this stud...

journal_title：Cancer

authors： Garcia MT,Acar BC,Jorda M,Gomez-Fernandez C,Ganjei-Azar P

更新日期：2007-02-25 00:00:00

abstract：:Thirty-one patients with advanced, biopsy-proven squamous cell carcinoma (SCC) of the head and neck were treated with intraarterial chemotherapy (IAC) and subsequent radical surgery. Cisplatin at 25 mg/d (4 hours of infusion) and bleomycin at 15 mg/d (20 hours of infusion) were administered for 10 consecutive days. Ra...

journal_title：Cancer

authors： Sulfaro S,Frustaci S,Volpe R,Barzan L,Comoretto R,Monfardini S,Carbone A

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Despite the characteristic histopathologic appearance of alveolar soft-part sarcoma (ASPS), its histogenesis remains unclear, and cytogenetic analysis of ASPS is limited to eight cases so far because of the extreme rarity of this disease. METHODS:The authors document a cytogenetic study of a primary case of...

journal_title：Cancer

authors： Joyama S,Ueda T,Shimizu K,Kudawara I,Mano M,Funai H,Takemura K,Yoshikawa H

更新日期：1999-10-01 00:00:00

abstract：:The clinical diagnosis of lymphangitic carcinomatosis of the lung has generally been confirmed by open lung or transthoracic needle biopsy, precedures with significant morbidity and mortality, particularly in patients with respiratory insufficiency. We present six cases of lymphangitic carcinomatosis diagnosed by tran...

journal_title：Cancer

authors： Aranda C,Sidhu G,Sasso LA,Adams FV

更新日期：1978-10-01 00:00:00

abstract：BACKGROUND:Hispanics now represent a majority of residents in Miami-Dade County, Florida. In this report, the authors present new cancer incidence and mortality data for South Florida's Hispanic men for the period 1990-1998 and compare them with data from a previous report from the 1980s. Periodic updating of cancer in...

journal_title：Cancer

authors： Wilkinson JD,Wohler-Torres B,Trapido E,Fleming LE,MacKinnon J,Voti L,Peace S

更新日期：2002-02-15 00:00:00

abstract：:An adequate operation for colorectal carcinoma involves removal of the primary tumor and wide excision of the mesentery with its contained regional lymph nodes and lymphovascular pathways. Enker and DeCosse state that radical resection, i.e., total mesenteric lymphadenectomy encompassing the origins of the complete ar...

journal_title：Cancer

authors： Leffall LD Jr

更新日期：1983-06-15 00:00:00

abstract：BACKGROUND:Some studies have suggested that the use of calcium channel blockers may increase the risk of cancer. A possible association of the use of calcium channel blockers with cancer incidence and cancer mortality was addressed using data from the Nurses' Health Study. METHODS:In this study, a total of 18,635 fema...

journal_title：Cancer

authors： Michels KB,Rosner BA,Walker AM,Stampfer MJ,Manson JE,Colditz GA,Hennekens CH,Willett WC

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Posttransplant lymphoproliferative disorder (PTLD) is a life-threatening complication of solid organ transplantation. Histologic heterogeneity and a lack of treatment standards have made evaluating clinical outcomes in specific patient populations difficult. This systematic literature review investigated the...

journal_title：Cancer

authors： Koff JL,Li JX,Zhang X,Switchenko JM,Flowers CR,Waller EK

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:A series of retrospective studies have reported that patients with human epidermal growth factor receptor 2(HER2)-positive breast cancer are at a greater risk of central nervous system (CNS) metastases. Trastuzumab, which does not cross the blood-brain barrier, has been associated with this increased risk. ...

journal_title：Cancer

authors： Musolino A,Ciccolallo L,Panebianco M,Fontana E,Zanoni D,Bozzetti C,Michiara M,Silini EM,Ardizzoni A

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:This study was performed to determine the incidence of central venous device-related blood stream infection and thrombosis in patients treated with moderate dose continuous-infusion interleukin-2 (IL-2). METHODS:The records of 160 consecutive patients treated at the University of Wisconsin Hospital and Clin...

journal_title：Cancer

authors： Eastman ME,Khorsand M,Maki DG,Williams EC,Kim K,Sondel PM,Schiller JH,Albertini MR

更新日期：2001-02-15 00:00:00