Giant cell tumors of synovium (Pigmented villonodular synovitis) involving the vertebral column.

Abstract:

:Giant cell tumors of synovium (pigmented villonodular synovitis) involving the vertebral column recently have been seen in two women: the third and fourth cases to be reported in the English-language literature. Unlike the previously reported cases, both these tumors grew outside the dura and produced symptoms of spinal cord compression. The first case involved lumbar vertebrae 5 and 6; the second, lumbar vertebrae 2 and 3. Even though initial resection of both tumors was incomplete, the patients improved postoperatively. One tumor was known to be unresectable at the time of surgery. In the other patient, a recurrence of symptoms required second and third resections 4 and 8 months after the first, respectively. Although synovial giant cell tumors rarely metastasize, the rate of local recurrence is high, especially if excision is incomplete. For this reason, close follow-up of patients with lesions in the spinal column is indicated. Increased physician awareness that synovial giant cell tumors can occur in the spine will help to ensure that these tumors are not misdiagnosed in this location.

journal_name

Cancer

journal_title

Cancer

authors

Weidner N,Challa VR,Bonsib SM,Davis CH Jr,Carrol TJ Jr

doi

10.1002/1097-0142(19860515)57:10<2030::aid-cncr282

subject

Has Abstract

pub_date

1986-05-15 00:00:00

pages

2030-6

issue

10

eissn

0008-543X

issn

1097-0142

journal_volume

57

pub_type

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