Abstract:
BACKGROUND:Fine-needle aspiration biopsy (FNAB) is a reliable, rapid, minimally invasive alternative to surgical biopsy when it is performed by physician specialists for the diagnosis of palpable masses. FNAB may be under-utilized in community hospitals in the U.S. because physicians without specialty training commonly provide the service, resulting in less reliable results. METHODS:Records were reviewed retrospectively from 730 consecutive FNAB cases that were performed and interpreted by expert cytopathologists practicing in an outpatient community hospital setting between 2000 and 2004. Data concerning patient demographics, referring physician specialty type, body sites, diagnoses, specimen adequacy, accuracy of diagnosis, and follow-up were examined and analyzed. RESULTS:FNAB was diagnostic in 93% of patients and was 95% accurate. There were 5 false-negative results and no false-positive results for the diagnosis of malignancy. The overall sensitivity of FNAB was 93%, and the specificity was 100%. Using either histology or clinical follow-up, the positive predictive value was 100%, and the negative predictive value was 99%. CONCLUSIONS:Highly reliable results can be obtained when patients are referred to specialty-trained cytopathologists practicing in the community for FNAB of palpable mass lesions. Clinicians are encouraged to seek out and support specialized FNAB services in their own communities.
journal_name
Cancerjournal_title
Cancerauthors
Florentine BD,Staymates B,Rabadi M,Barstis J,Black A,Cancer Committee of the Henry Mayo Newhall Memorial Hospital.doi
10.1002/cncr.21976subject
Has Abstractpub_date
2006-07-15 00:00:00pages
406-16issue
2eissn
0008-543Xissn
1097-0142journal_volume
107pub_type
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