Total body irradiation with 8 MeV X-rays in generalized malignant disease.

abstract：:Although training programs exist in both medical oncology and geriatrics (approved by the American Board of Internal Medicine), neither is adequate to ensure an appropriate supply of physicians to assume a leadership role in the treatment of the increasing number of geriatric patients who have or will develop a malign...

journal_title：Cancer

authors： Bennett JM,Sahasrabudhe DM,Hall WJ

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:: Patients with oral premalignant lesions (OPL) present with oral squamous cell carcinomas (OSCC) at a much higher rate than the general population. There are currently no useful markers that indicate specifically which OPLs are most likely to progress. Three small integrin binding ligands N-linked glycoprot...

journal_title：Cancer

authors： Ogbureke KU,Abdelsayed RA,Kushner H,Li L,Fisher LW

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:The presence of tumor at the inked margins (IMs) of breast specimens is associated with an increased risk of local recurrence after breast-conserving therapy for invasive breast carcinoma and ductal carcinoma in situ (DCIS). Given the importance of margin status, some have advocated the use of shaved margins...

journal_title：Cancer

authors： Guidi AJ,Connolly JL,Harris JR,Schnitt SJ

更新日期：1997-04-15 00:00:00

abstract：BACKGROUND:Efforts to improve local control and survival by increasing the dose of once-daily radiation therapy beyond 70 Gray (Gy) for patients with malignant gliomas has yet been unsuccessful. Hyperfractionated radiation therapy (HF) should allow for delivery of a higher total dose without increasing normal tissue la...

journal_title：Cancer

authors： Werner-Wasik M,Scott CB,Nelson DF,Gaspar LE,Murray KJ,Fischbach JA,Nelson JS,Weinstein AS,Curran WJ Jr

更新日期：1996-04-15 00:00:00

abstract：:The short term addition of nandrolone decanoate to combination chemotherapy given to patients with unresectable non-small cell lung cancer was evaluated in a randomized, prospective trial. Patients were treated with doxorubicin 50 mg/M2 intravenously, cyclophosphamide 300 mg/M2 intravenously, CCNU 50 mg/M2 orally, vin...

journal_title：Cancer

authors： Chlebowski RT,Herrold J,Ali I,Oktay E,Chlebowski JS,Ponce AT,Heber D,Block JB

更新日期：1986-07-01 00:00:00

abstract：:The use of prostate-specific antigen (PSA) as a screening test remains controversial. There have been several attempts to refine PSA measurements to improve its predictive value. These modifications, including PSA density, PSA kinetics, and the measurement of PSA isoforms, have met with limited success. Therefore, com...

journal_title：Cancer

authors： Herman MP,Dorsey P,John M,Patel N,Leung R,Tewari A

更新日期：2009-07-01 00:00:00

abstract：:A tumor colony assay (TCA) was evaluated for its ability to predict anticancer drug responses in an N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide (FANFT)-induced murine bladder tumor (MBT) model. Ten anticancer drugs were evaluated in vivo and in vitro using four MBT cell lines (40 drug responses). Using the optimum c...

journal_title：Cancer

authors： Niell HB,Soloway MS,Wood CA,McCallum LW,Webster K

更新日期：1983-08-15 00:00:00

abstract：BACKGROUND:Cell cycle proteins are important markers in predicting tumor behavior in urothelial carcinoma of the bladder. The objectives of this study were 1) to determine the expression levels of some of those markers in a series of patients with bladder carcinoma, 2) to define their value in distinguishing T1a (minim...

journal_title：Cancer

authors： Mhawech P,Greloz V,Oppikofer C,Szalay-Quinodoz I,Herrmann F

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:: Histologic parameters of melanoma deposits in sentinel lymph nodes (SLNs) have been shown to be predictive of clinical outcome and the presence or absence of tumor in non-SLNs, but assessment of these parameters is prone to interobserver variation. METHODS:: Histologic sections of 44 SLNs containing metas...

journal_title：Cancer

authors： Murali R,Cochran AJ,Cook MG,Hillman JD,Karim RZ,Moncrieff M,Starz H,Thompson JF,Scolyer RA

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:It has been suggested that tissue factor (TF) plays an important role in tumor metastasis. Its expression in sarcoma cells was reported to up-regulate the vascular endothelial growth factor (VEGF) gene and thereby enhance tumor angiogenesis, which is essential to tumor metastasis. Although many malignant tum...

journal_title：Cancer

authors： Seto S,Onodera H,Kaido T,Yoshikawa A,Ishigami S,Arii S,Imamura M

更新日期：2000-01-15 00:00:00

abstract：:With the improved survival of children with cancer, increased attention is being focused on the health status of survivors. The ultimate objective of this research is to use the results to design and test rational intervention strategies directed toward reduction of morbidity and mortality associated with the diagnosi...

journal_title：Cancer

authors： Robison LL

更新日期：1993-05-15 00:00:00

abstract：BACKGROUND:An estimated 5-10% of all pancreatic adenocarcinomas have a hereditary association. The objective of the current study was to characterize the clinical and pathologic features of familial pancreatic carcinoma and to determine potential differences in demographics, risk factors, and outcomes between familial ...

journal_title：Cancer

authors： James TA,Sheldon DG,Rajput A,Kuvshinoff BW,Javle MM,Nava HR,Smith JL,Gibbs JF

更新日期：2004-12-15 00:00:00

abstract：:A case of malignant eccrine poroma with lymph node metastases is described. The patient had a nodular growth of the right thigh 2 years before its first excision. Local recurrence in the scar occurred in 6 months, and by 8 months a right groin lymph node was involved. Subsequent skin nodules of the right thigh occurre...

journal_title：Cancer

authors： Bottles K,Sagebiel RW,McNutt NS,Jensen B,Deveney K

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:Five-year survival rates after resection of liver metastases from colorectal carcinoma are close to 25%. Recurrences occur in two-thirds of the patients after surgery. Selection of patients likely to benefit from surgery remains controversial and subjective. METHODS:Data from 1568 patients with resected liv...

journal_title：Cancer

authors： Nordlinger B,Guiguet M,Vaillant JC,Balladur P,Boudjema K,Bachellier P,Jaeck D

更新日期：1996-04-01 00:00:00

abstract：:The American Cancer Society estimates that nearly a million new cases of cancer will occur and that approximately a half million lives will be lost in 1987. These figures may double by the year 2000 primarily because of our aging population, with age being the leading risk factor for cancer. It is believed that the ma...

journal_title：Cancer

authors： Williams PA,Williams M

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:Antithymocyte globulin (ATG) is an important component of conditioning regimens to prevent severe graft-versus-host disease (GVHD) in patients undergoing unmanipulated, haploidentical stem cell transplantation (haplo-SCT). However, to the authors' knowledge, the optimal dose of ATG is unknown. METHODS:In th...

journal_title：Cancer

authors： Chang YJ,Wang Y,Mo XD,Zhang XH,Xu LP,Yan CH,Chen H,Chen YH,Chen Y,Han W,Wang FR,Wang JZ,Liu KY,Huang XJ

更新日期：2017-08-01 00:00:00

abstract：:One hundred twenty two children with non-Hodgkin's lymphoma were studied from January 1966 to December 1975. The first group (1966-1972) did not receive an uniform treatment. The second group (1973-1975) entered in a G.A.T.L.A. protocol consisting of: vincristine-prednisone plus surgery and/or radiotherapy as inductio...

journal_title：Cancer

authors： Cebrian-Bonesana A,Schvartzman E,Roca-Garcia C,Pependieck C,Sackmann-Muriel S,Ojeda FG,Kvicala R,Pavlovsky S,Lein JM,Penchansky L

更新日期：1978-06-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to examine local definitive therapy for nonmetastatic breast cancer with the Patterns of Care Breast and Prostate Cancer (POCBP) study of the National Program of Cancer Registries (Centers for Disease Control and Prevention). METHODS:POCBP medical record data were re-abstracted...

journal_title：Cancer

authors： Anderson RT,Morris CR,Kimmick G,Trentham-Dietz A,Camacho F,Wu XC,Sabatino SA,Fleming ST,Lipscomb J

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Factors that could optimize the management of pediatric spinal cord astrocytoma remain unclear and controversial. METHODS:To determine the factors that influence the prognosis of pediatric patients with spinal cord astrocytomas, a series of 73 consecutive patients at 13 French treatment centers with histolo...

journal_title：Cancer

authors： Bouffet E,Pierre-Kahn A,Marchal JC,Jouvet A,Kalifa C,Choux M,Dhellemmes P,Guérin J,Tremoulet M,Mottolese C

更新日期：1998-12-01 00:00:00

abstract：:Seventeen patients with disseminated malignant melanoma received a daily oral regimen of tamoxifen, 100 mg/m2. All patients had prior chemotherapy and predominantly visceral involvement. None of the patients had an objective regression and most (71%) had progressive disease at the time of first reassessment. Moderate ...

journal_title：Cancer

authors： Creagan ET,Ingle JN,Ahmann DL,Green SJ

更新日期：1982-04-01 00:00:00

abstract：:An unusual case of myeloproliferative disorder in which mature and immature myeloid cells were found to contain unusual cytoplasmic inclusions is reported. By light microscopy, these inclusions could be observed with Wright's stain. By electron microscopy they appeared to consist of a pale, finely granular material wi...

journal_title：Cancer

authors： Coppola A,O'Connor J

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:To determine whether high-risk patients with hematuria receive evaluation according to guideline recommendations. METHODS:We recently performed a screening study for bladder cancer using a urine-based tumor marker in 1502 subjects at high risk based on aged > or = 50 years, > or = 10-year smoking history, a...

journal_title：Cancer

authors： Elias K,Svatek RS,Gupta S,Ho R,Lotan Y

更新日期：2010-06-15 00:00:00

abstract：:Forty-six examples of carcinoma cuniculatum, a rare variant of squamous cell carcinoma of the skin, were studied by means of light and electron microscopy and immunoperoxidase techniques. The tumors usually presented as ulcerated, fungating, and polypoid masses with openings of sinus tracts onto the skin surface that ...

journal_title：Cancer

authors： Kao GF,Graham JH,Helwig EB

更新日期：1982-06-01 00:00:00

abstract：:The techniques of self breast examination and the clinical examination of the breasts are described briefly. The potential value and the limitations of these tests in screening for breast cancer are reviewed. In a Cancer Society Monograph in 1958, Haagensen said, "It is probable that, from the point of view of the gre...

journal_title：Cancer

authors： Venet L

更新日期：1980-08-15 00:00:00

abstract：:Because Forssman antigen, one of the most well-known heteroantigens, has been noted in certain cancerous tissues, it would seem that the serum levels of the Forssman antibody of patients with these cancers would be low, owing to the absorption of the naturally occurring antibody by the Forssman antigen-containing canc...

journal_title：Cancer

authors： Hirayama R,Hirokawa K,Takagi Y,Utsuyama M,Maejima S,Takemura K,Mishima Y,Makinodan T

更新日期：1989-04-15 00:00:00

abstract：BACKGROUND:During the last two decades, a rising incidence of adenocarcinoma of the esophagus has been observed in the Western world. The prognostic relevance of tumor-biological factors, such as DNA ploidy or c-erbB-2 overexpression, for overall survival following complete resection is still unknown. METHODS:In a ret...

journal_title：Cancer

authors： Nakamura T,Nekarda H,Hoelscher AH,Bollschweiler E,Harbeck N,Becker K,Siewert JR,Harbec N corrected to Harbeck N

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:The intraoperative evaluation of axillary sentinel lymph nodes (SLNs) allows the surgeon to complete axillary dissection in 1 setting at the time of the primary breast surgery. However, to the authors' knowledge, there is no consensus regarding the optimal method for intraoperative evaluation of SLNs in brea...

journal_title：Cancer

authors： Krishnamurthy S,Meric-Bernstam F,Lucci A,Hwang RF,Kuerer HM,Babiera G,Ames FC,Feig BW,Ross MI,Singletary E,Hunt KK,Bedrosian I

更新日期：2009-04-01 00:00:00

abstract：:The case of a 41-year-old man with testicular mixed germ cell-sex cord stroma tumor is reported. The patient noticed a gradual, painless, right-sided testicular enlargement 4 years before being treated by radical orchiectomy. The testis contained a centrally located tumor. There was no evidence of metastases. An histo...

journal_title：Cancer

authors： Matoŝka J,Talerman A

更新日期：1989-11-15 00:00:00

abstract：BACKGROUND:Prognosis of patients with adenocarcinoma of the pancreatic body and tail is extremely poor. Anatomically, this part of the pancreas is thin, and cancerous invasion to the retropancreatic structures occurs easily. The majority of patients have residual tumor in the retroperitoneal tissues after conventional ...

journal_title：Cancer

authors： Ozaki H,Kinoshita T,Kosuge T,Yamamoto J,Shimada K,Inoue K,Koyama Y,Mukai K

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:Estimates of the fecal occult blood test (FOBT) (Hemoccult II) sensitivity differed widely between screening trials and led to divergent conclusions on the effects of FOBT screening. We used microsimulation modeling to estimate a preclinical colorectal cancer (CRC) duration and sensitivity for unrehydrated F...

journal_title：Cancer

authors： Lansdorp-Vogelaar I,van Ballegooijen M,Boer R,Zauber A,Habbema JD

更新日期：2009-06-01 00:00:00