Primary retroperitoneal seminoma.

Abstract:

:In a retrospective review (1950-1975) of the Mayo Clinic experience with seminomas (483 cases), twelve patients (2.5%) were found to have a retroperitoneal seminoma without evidence of testicular involvement. The mean age was 47 years (range, 31-67). Eleven patients were treated by radiation alone, with doses ranging from less than 2,000-5,800 rads. Seven patients are alive with a median follow-up of six years. The median survival of the five that died is ten months. Good prognostic factors are typical histopathology and an encapsulated tumor. Poor prognostic factors are atypical histopathology, a nonencapsulated tumor, a symptomatic abdominal mass and a nonfunctioning kidney at the time of diagnosis. Although the review includes few patients, it seems reasonable to suggest irradiation of the tumor bed and para-aortic lymph nodes to a minimum dose of 2,000 rads. Prophylactic treatment of the mediastinum and supraclavicular lymph nodes should be considered if one or more of the poor prognostic factors are present.

journal_name

Cancer

journal_title

Cancer

authors

Buskirk SJ,Evans RG,Farrow GM,Earle JD

doi

10.1002/1097-0142(19820501)49:9<1934::aid-cncr2820

subject

Has Abstract

pub_date

1982-05-01 00:00:00

pages

1934-6

issue

9

eissn

0008-543X

issn

1097-0142

journal_volume

49

pub_type

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