Abstract:
:In a retrospective review (1950-1975) of the Mayo Clinic experience with seminomas (483 cases), twelve patients (2.5%) were found to have a retroperitoneal seminoma without evidence of testicular involvement. The mean age was 47 years (range, 31-67). Eleven patients were treated by radiation alone, with doses ranging from less than 2,000-5,800 rads. Seven patients are alive with a median follow-up of six years. The median survival of the five that died is ten months. Good prognostic factors are typical histopathology and an encapsulated tumor. Poor prognostic factors are atypical histopathology, a nonencapsulated tumor, a symptomatic abdominal mass and a nonfunctioning kidney at the time of diagnosis. Although the review includes few patients, it seems reasonable to suggest irradiation of the tumor bed and para-aortic lymph nodes to a minimum dose of 2,000 rads. Prophylactic treatment of the mediastinum and supraclavicular lymph nodes should be considered if one or more of the poor prognostic factors are present.
journal_name
Cancerjournal_title
Cancerauthors
Buskirk SJ,Evans RG,Farrow GM,Earle JDdoi
10.1002/1097-0142(19820501)49:9<1934::aid-cncr2820subject
Has Abstractpub_date
1982-05-01 00:00:00pages
1934-6issue
9eissn
0008-543Xissn
1097-0142journal_volume
49pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:There is considerable evidence that one of the strongest risk factors for breast carcinoma can be assessed from the mammographic appearance of the breast. However, the magnitude of the risk factor and the reliability of the prediction depend on the method of classification. Subjective classification requires...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19970701)80:1<66::aid-cncr
更新日期:1997-07-01 00:00:00
abstract::Sequential corrected creatinine clearance (CCC) evaluations were obtained in 30 patients treated with intra-arterial and/or intravenous cis-diamminedichloroplatinum-II (CDP). The dose was 150 mg/M2 administered with mannitol diuresis at 2 to 3 weekly intervals. Four hundred fifty-three courses were administered (range...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19870501)59:9<1577::aid-cncr2820
更新日期:1987-05-01 00:00:00
abstract:BACKGROUND:Although K-ras is the most frequently mutated protooncogene in colorectal carcinoma, the specific role and timing of K-ras mutations in colorectal carcinogenesis remains controversial. In the current study, the authors investigated associations with K-ras mutation in incident sporadic colorectal adenomas tha...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21721
更新日期:2006-03-01 00:00:00
abstract::Six patients with Hodgkin's disease (HD) and demonstrable serum antibodies to human immunodeficiency virus (HIV) and two additional patients with HD belonging to HIV-associated high-risk groups but with negative HIV serology were studied. All patients were men and ranged in age from 21 to 45 years. The HIV risk factor...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19910401)67:7<1865::aid-cncr2820
更新日期:1991-04-01 00:00:00
abstract:BACKGROUND:To assess the ability of [(18)F]fluorodeoxyglucose (F-18 FDG) positron emission tomography (PET) to predict the viability of residual masses after chemotherapy in patients with metastatic nonseminomatous germ cell tumors (GCT), PET results were compared in a blinded analysis with computed tomography (CT) sca...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.10494
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:Pathologically, benign prostatic hyperplasia (BPH) is not considered a precursor for prostate carcinoma. However, because the two conditions share not only a similar hormonal environment within the prostate but also several common risk factors, it is possible that men with BPH may be at increased risk of pro...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11710
更新日期:2003-10-15 00:00:00
abstract::With increasing numbers of survivors from cancer at a young age, the issue of fertility preservation has assumed greater importance. This review describes normal ovarian and testicular function and summarizes what is known about the effect of chemotherapy and radiotherapy on the gonads and uterus. All young patients w...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.26045
更新日期:2011-05-15 00:00:00
abstract::A young woman with a very extensive intramedullary hemangioblastoma of the spinal cord was treated with a moderately high dose of irradiation after biopsy only of the tumor. Now, five years following treatment, there have been no radiation sequelae and no evidence of progressive disease. ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800101)45:1<49::aid-cncr282045
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:Despite growing evidence and support for shared decision making, little is known about the experiences of parents who hold more active roles than they wish. METHODS:This was a prospective cohort study of 372 parents of children with cancer and their oncologists at 2 academic pediatric hospitals. Parents wer...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.31939
更新日期:2019-04-15 00:00:00
abstract::Flow cytometry studies of the DNA distribution of tumor cells from 92 human breast cancers showed measurable aneuploidy (hyperploidy) in 83 cases (92%). The DNA ploidy values were unimodal in each case, but there was a bimodal distribution for the entire series. One group of tumors had a diploid or near diploid DNA di...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810815)48:4<980::aid-cncr28204
更新日期:1981-08-15 00:00:00
abstract:BACKGROUND:Cyclins, cyclin dependent kinases (cdks), and their inhibitors act in combination to regulate progression through the cell cycle and often are dysregulated in carcinoma. The authors hypothesized that cyclin E plays an important role in ovarian carcinogenesis and that its overexpression may be an indicator of...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21767
更新日期:2006-05-01 00:00:00
abstract::The livers of 345 autopsy cases of chronic liver disease were examined for macroregenerative nodule (MRN), a large nodular lesion more than 10 mm in diameter. A total of 86 lesions of MRN was found in 49 cases (14.2%): 32 were from 191 cases of hepatocellular carcinoma (HCC), 16 were from 148 cases of cirrhosis only, ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19880101)61:1<99::aid-cncr282061
更新日期:1988-01-01 00:00:00
abstract:BACKGROUND:Although protein expressions of glucocorticoid receptor (GR), estrogen receptors (ERα and ERβ), progesterone receptor A (PgR-A), and androgen receptor (AR) were shown to play roles in the growth and differentiation of normal thymus and thymic tumors, to the authors' knowledge their association with patient c...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.26061
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Sequential systematic biopsies after radiotherapy (RT) for prostate carcinoma were evaluated with respect to radiation effect, tumor differentiation, and prostate specific antigen (PSA) staining, and these histopathologic parameters were correlated with local outcome. METHODS:Since 1990, transrectal ultraso...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::A clinicopathologic study of 48 cases of pleomorphic lipoma from the files of the Armed Forces Institute of Pathology reveals that this tumor occurs principally in males (83%) in the fifth to seventh decades (mean 57 years) and shows a predilection for the posterior neck, shoulder, and back. Typically, the lesion appe...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19810101)47:1<126::aid-cncr28204
更新日期:1981-01-01 00:00:00
abstract::The prognostic significance of histologic tumor grade has been evaluated in 1537 women entered into the Ludwig Trials I-IV of adjuvant therapy for node-positive breast cancer. Tumor grade was determined on histologic review of primary tumor sections by two central review pathologists using a modification of the Bloom ...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/1097-0142(19861215)58:12<2662::aid-cncr282
更新日期:1986-12-15 00:00:00
abstract::Seven hundred ninety-five patients were adenocarcinomas of the proximal colon were reviewed. Two hundred forty-five patients presented with disseminated disease at the time of diagnosis, and were analyzed to identify mechanisms and sites of disease spread. Five hundred fifty patients underwent radical resection, and w...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840115)53:2<360::aid-cncr28205
更新日期:1984-01-15 00:00:00
abstract:BACKGROUND:The current randomized, controlled, multicenter clinical trial was conducted to investigate the efficacy of concurrent neoadjuvant chemotherapy (NCT) and estrogen deprivation in patients with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer. METHODS:Eli...
journal_title:Cancer
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/cncr.32057
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Most commercial fecal occult blood tests (FOBT) used for colorectal carcinoma screening of Western populations are guaiac-based, manually developed, subjective, and sensitive to dietary components. Preliminary studies demonstrated the unsuitability of these tests for screening a Chinese population. The goal ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11369
更新日期:2003-05-15 00:00:00
abstract::The cellular DNA content of 15 benign and 34 malignant primary bone tumors was analyzed by means of flow cytophotometry. All benign tumors except one of questionable histologic type exhibited a normal DNA content (diploid), whereas 23 of 34 malignant tumors showed an abnormal DNA content (aneuploid). Closer analysis r...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19840101)53:1<129::aid-cncr28205
更新日期:1984-01-01 00:00:00
abstract::One hundred ninety patients who had advanced active Hodgkin's disease, lymphosarcoma, or reticulum cell sarcoma were treated with a combination of cyclophosphamide, vincristine, procarbazine, and prednisone (COPP) given in a cyclical fashion every month. Complete remission was produced in 91 of 138 (66%) patients with...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197510)36:4<1241::aid-cncr282036
更新日期:1975-10-01 00:00:00
abstract:BACKGROUND:In multidisciplinary assessment clinics for screen-detected breast lesions, onsite cytopathologists provide immediate results of fine-needle aspiration biopsies (FNABs) and this information is used for patient counseling and treatment planning. Such consultation is not possible for the increasing proportion ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21939
更新日期:2006-06-25 00:00:00
abstract::Canada is a westernized, market-economy nation with a publicly funded health care and cancer control system and has health indices reflective of a high-resource economy. Provision of health services is in accord with the Canada Health Act and is implemented through federal, provincial, and territorial relations wherei...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.26053
更新日期:2011-05-15 00:00:00
abstract:BACKGROUND:Although there is no doubt that bisphosphonates (BPs), specific inhibitors of osteoclasts, are beneficial for the treatment of bone metastases, their effects on visceral metastases are unclear. The effect of zoledronic acid (ZOL) was examined in vivo on lung metastasis progression and animal survival, and in...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21530
更新日期:2005-12-01 00:00:00
abstract::Although training programs exist in both medical oncology and geriatrics (approved by the American Board of Internal Medicine), neither is adequate to ensure an appropriate supply of physicians to assume a leadership role in the treatment of the increasing number of geriatric patients who have or will develop a malign...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19971001)80:7<1351::aid-cn
更新日期:1997-10-01 00:00:00
abstract::Tobacco use in the US is currently responsible for more than 30% of all cancer deaths, including cancers of the lung, larynx, oral cavity, pharynx, pancreas, kidney, bladder, and cervix. The lung cancer epidemic in men and then women since the turn of the century followed an increased prevalence of cigarette smoking. ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19881015)62:1+<1702::aid-cncr282
更新日期:1988-10-15 00:00:00
abstract::A Chinese patient with documented hepatocellular carcinoma (HCC) satisfied the criteria of Everson and Cole for spontaneous regression of malignant tumors. Subsequently he survived a tumor-free period of at least 13 years. During the period of regression, shrinkage of liver coincided with a rise of SGOT to a level com...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820715)50:2<332::aid-cncr28205
更新日期:1982-07-15 00:00:00
abstract::The case of a 41-year-old man with testicular mixed germ cell-sex cord stroma tumor is reported. The patient noticed a gradual, painless, right-sided testicular enlargement 4 years before being treated by radical orchiectomy. The testis contained a centrally located tumor. There was no evidence of metastases. An histo...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19891115)64:10<2146::aid-cncr282
更新日期:1989-11-15 00:00:00
abstract::Testis cancer and ichthyosis are both relatively rare diseases. Hence the finding of six individuals with both these conditions in a small population with testicular cancer is highly conspicuous and indicates some kind of connection among such persons. Despite the identical clinical appearances of their ichthyoses, th...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910201)67:3<730::aid-cncr28206
更新日期:1991-02-01 00:00:00
abstract::The binding of soybean agglutinin (SBA) lectin to routinely processed surgical pathology material from cases of prostatic hyperplasia, atypical hyperplasia, and adenocarcinoma was studied using an immunoperoxidase technique. Positive staining was obtained in eight of eight cases of nodular hyperplasia, eight of eight ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19890415)63:8<1583::aid-cncr2820
更新日期:1989-04-15 00:00:00