Small cell carcinoma of the major salivary glands.

Abstract:

:Small cell carcinoma is primarily a pulmonary neoplasm that rarely arises in extrapulmonic sites including salivary glands of the head and neck. Twelve cases of small cell carcinoma of salivary gland origin were retrieved from the Armed Forces Institute of Pathology files. Six tumors occurred in the parotid gland and six in the submandibular gland. Tumors were classified into two categories: those with areas of histologically typical small cell carcinoma (7 cases) and those with areas of typical small cell carcinoma with foci of ductal differentiation (5 cases). Follow-up information was available in all 12 cases. Electron microscopy was done on eight tumors; only one demonstrated round electron dense intracytoplasmic neurosecretory granules. These observations further support evidence in the literature suggesting most of the small cell carcinomas of salivary gland origin are not true neuroendocrine ("oat cell") carcinomas, but actually are small cell ductal carcinomas. These tumors appear to have a better prognosis than small cell carcinoma of the lung or nonsalivary gland sites in the head and neck region, with an estimated 2- and 5-year survival of 70 and 46%, respectively.

journal_name

Cancer

journal_title

Cancer

authors

Gnepp DR,Corio RL,Brannon RB

doi

10.1002/1097-0142(19860801)58:3<705::aid-cncr28205

subject

Has Abstract

pub_date

1986-08-01 00:00:00

pages

705-14

issue

3

eissn

0008-543X

issn

1097-0142

journal_volume

58

pub_type

杂志文章

相关文献

CANCER文献大全
  • Cancer risk in male veterans utilizing the Veterans Administration medical system.

    abstract::Age-specific incidence curves, cumulative rates, and relative risks were estimated for selected malignancies among male veterans utilizing the Veterans Administration (VA) medical system during 1970 to 1982. Relative risks for malignant tumors of the lung, bronchus, larynx, oral cavity, and esophagus in males using VA...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19890901)64:5<1160::aid-cncr2820

    authors: Harris RE,Hebert JR,Wynder EL

    更新日期:1989-09-01 00:00:00

  • A population-based study of the impact of specific symptoms on quality of life in women with breast cancer 1 year after diagnosis.

    abstract:BACKGROUND:Whereas the role of specific symptoms, such as pain and fatigue, for quality of life (QOL) is unquestioned, their relative importance for long-lasting impairments in QOL in cancer patients has rarely been assessed quantitatively. The authors, therefore, aimed to identify symptoms most predictive of limitatio...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.22274

    authors: Arndt V,Stegmaier C,Ziegler H,Brenner H

    更新日期:2006-11-15 00:00:00

  • Magnetic resonance imaging as a biomarker in renal cell carcinoma.

    abstract::The ability to noninvasively discriminate the most common types of renal cell carcinoma (RCC) based on their magnetic resonance imaging (MRI) appearances or their magnetic resonance phenotypes is achievable. Intracellular lipids, a histologic characteristic of the clear cell RCC, can be identified on chemical shift MR...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.24237

    authors: Pedrosa I,Alsop DC,Rofsky NM

    更新日期:2009-05-15 00:00:00

  • Overcoming sociodemographic factors in the care of patients with testicular cancer at a safety net hospital.

    abstract:BACKGROUND:The objective of this study was to determine whether standardized treatment of germ cell tumors (GCTs) could overcome sociodemographic factors limiting patient care. METHODS:The records of all patients undergoing primary treatment for GCTs at both a public safety net hospital and an academic tertiary care c...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.33076

    authors: Chertack N,Ghandour RA,Singla N,Freifeld Y,Hutchinson RC,Courtney K,Bowman IA,Arafat W,Meng X,Moore JA,Aydin AM,Sagalowsky AI,Margulis V,Lotan Y,Woldu SL,Bagrodia A

    更新日期:2020-10-01 00:00:00

  • Intracarotid chemotherapy with etoposide and cisplatin for malignant brain tumors.

    abstract::Chemotherapy for tumors of the central nervous system has a limited efficacy presumably because of restricted blood-brain barrier permeability. The advantage of regional intra-arterial administration of anticancer drugs is an increased uptake during the first passage of the drugs through tumor capillaries. Twenty pati...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19910601)67:11<2844::aid-cncr282

    authors: Madajewicz S,Chowhan N,Iliya A,Roque C,Beaton R,Davis R,Fertman S,Meek A,Alvarez O,Pampati M

    更新日期:1991-06-01 00:00:00

  • Second solid cancers after allogeneic hematopoietic stem cell transplantation.

    abstract:BACKGROUND:The objective of this study was to establish the incidence and risk factors for the development of second solid cancers after allogeneic hematopoietic stem cell transplantation (allo-HSCT). METHODS:The authors reviewed the case files of 926 consecutive patients who underwent allo-HSCT at their institution b...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.22375

    authors: Gallagher G,Forrest DL

    更新日期:2007-01-01 00:00:00

  • Patterns and predictors of cancer-related fatigue in ovarian and endometrial cancers: 1-year longitudinal study.

    abstract:BACKGROUND:Fatigue is a common and distressing symptom for patients with gynecologic cancers. Few studies have empirically examined whether it spontaneously resolves. This study was aimed at identifying longitudinal patterns of fatigue and predictors of clinically significant fatigue 1 year after treatment completion. ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.32927

    authors: Poort H,de Rooij BH,Uno H,Weng S,Ezendam NPM,van de Poll-Franse L,Wright AA

    更新日期:2020-08-01 00:00:00

  • Chronic lymphocytic leukemia. Immunologic markers and functional properties of the leukemic cells.

    abstract::In 230 cases of chronic lymphocytic leukemia (CLL), marker analysis was performed with rosette techniques and a panel of xeno-antisera. A monoclonal B-cell proliferation was found in the majority of cases (94%). In most cases, the B-cells carried IgM, with or without IgD. Cytoplasmic immunoglobulin-inclusion bodies we...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19821215)50:12<2826::aid-cncr282

    authors: van der Reijden HJ,van der Gaag R,Pinkster J,Rümke HC,van't Veer MB,Melief CJ,von dem Borne AE

    更新日期:1982-12-15 00:00:00

  • Patterns of recurrence of rectal cancer after potentially curative surgery.

    abstract::The results of surgical treatment alone for 142 cases of carcinoma of the rectum and rectosigmoid from the Massachusetts General Hospital were reviewed. The incidence of local failure as any component of failure was found to be strongly dependent on the pathologic stage, and for Dukes' A was 8.0% (3/39); Dukes' B, 31%...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19831001)52:7<1317::aid-cncr2820

    authors: Rich T,Gunderson LL,Lew R,Galdibini JJ,Cohen AM,Donaldson G

    更新日期:1983-10-01 00:00:00

  • Significance of minimal residual disease monitoring by real-time quantitative polymerase chain reaction in core binding factor acute myeloid leukemia for transplantation outcomes.

    abstract:BACKGROUND:Despite the well-defined role of minimal residual disease (MRD) monitoring by real-time quantitative polymerase chain reaction (RT-PCR) for RUNX1/RUNX1T1 and CBFB-MYH11 transcripts in core binding factor (CBF) acute myeloid leukemia (AML) after intensive chemotherapy, there has been a paucity of data assessi...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.32769

    authors: Yalniz FF,Patel KP,Bashir Q,Marin D,Ahmed S,Alousi AM,Chen J,Ciurea SO,Rezvani K,Popat UR,Shpall EJ,Champlin RE,Oran B

    更新日期:2020-05-15 00:00:00

  • Analysis of the levels of CA125, carcinoembryonic antigen, and CA19-9 in the cervical mucus for a detection of cervical adenocarcinoma.

    abstract::To verify whether analysis of the levels of CA125, carcinoembryonic antigen (CEA), and CA19-9 in the cervical mucus is effective for a detection of cervical adenocarcinomas or not, simultaneous measurement of these three tumor markers in the cervical mucus samples from women without gynecologic disorders, with leiomyo...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19880801)62:3<541::aid-cncr28206

    authors: Fujii S,Konishi I,Nanbu Y,Nonogaki H,Kobayashi F,Sagawa N,Mori T,Endo K

    更新日期:1988-08-01 00:00:00

  • Laparoscopic extraperitoneal para-aortic lymphadenectomy in locally advanced cervical cancer: a prospective correlation of surgical findings with positron emission tomography/computed tomography findings.

    abstract:BACKGROUND:Failure to detect metastasis to para-aortic nodes in patients with locally advanced cervical cancer leads to suboptimal treatment. No previous studies have prospectively compared positron emission tomography (PET)/computed tomography (CT) with laparoscopic extraperitoneal staging in the evaluation of para-ao...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/cncr.25739

    authors: Ramirez PT,Jhingran A,Macapinlac HA,Euscher ED,Munsell MF,Coleman RL,Soliman PT,Schmeler KM,Frumovitz M,Ramondetta LM

    更新日期:2011-05-01 00:00:00

  • Brain metastasis in the natural history of small-cell lung cancer: 1972-1979.

    abstract::The records of 134 patients with small-cell lung cancer who had been seen at Henry Ford Hospital between 1972-1979 were reviewed with emphasis on brain metastasis. Brain metastasis developed in 28% of the patients; 21% had brain metastasis at the time of diagnosis and in 7% it developed later (de novo). In 9%, the chi...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820815)50:4<752::aid-cncr28205

    authors: Doyle TJ

    更新日期:1982-08-15 00:00:00

  • Body composition in cachexia resulting from malignant and non-malignant diseases.

    abstract::The body composition of 23 patients with cachexia resulting from malignant or benign inflammatory disease was studied. Skinfold thickness and radioisotope tracer measurements enabled us to estimate total body fat, lean body mass, the ratio of fat loss to lean body loss, erythrocyte and plasma volumes, total body water...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19801101)46:9<2041::aid-cncr2820

    authors: Watson WS,Sammon AM

    更新日期:1980-11-01 00:00:00

  • Prostate cancer outcomes for men aged younger than 65 years with Medicaid versus private insurance.

    abstract:BACKGROUND:In the current national debate regarding private insurance versus Medicaid expansion, understanding how insurance is associated with racial disparities in prostate cancer (CaP) outcomes has broad policy implications. In the current study, the authors examined the association between insurance status, race, a...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.31106

    authors: Mahal AR,Mahal BA,Nguyen PL,Yu JB

    更新日期:2018-02-15 00:00:00

  • BACON (bleomycin, adriamycin, CCNU, oncovin and nitrogen mustard) in squamous lung cancer. Experience in fifty patients.

    abstract::Fifty patients with inoperable squamous carcinoma of the lung. 38 with extensive, and 12 with limited disease, were treated with BACON. Tumor regression greater than 50% was observed in 17 patients (45%) with extensive, and four patients (33%) with limited disease. Stabilization of disease for greater than or equal to...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(197603)37:3<1237::aid-cncr282037

    authors: Livingston RB,Fee WH,Einhorn LH,Burgess MA,Freireich EJ,Gottlieb JA,Farber MO

    更新日期:1976-03-01 00:00:00

  • Detection of tumor cells in the portal and peripheral blood of patients with colorectal carcinoma using competitive reverse transcriptase-polymerase chain reaction.

    abstract:BACKGROUND:In spite of many reports, it remains unclear whether the presence of tumor cells in circulating blood flow predicts a poor prognosis. METHODS:Competitive seminested reverse transcriptase-polymerase chain reaction (RT-PCR), a technique for the quantitative detection of tumor cells, was applied to detect the ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(20010901)92:5<1251::aid-cncr1445

    authors: Sadahiro S,Suzuki T,Tokunaga N,Yurimoto S,Yasuda S,Tajima T,Makuuchi H,Murayama C,Matsuda K

    更新日期:2001-09-01 00:00:00

  • Prevention of severe menorrhagia in oncology patients with treatment-induced thrombocytopenia by luteinizing hormone-releasing hormone agonist and depo-medroxyprogesterone acetate.

    abstract:BACKGROUND:Menorrhagia is a serious complication in young female oncology patients who suffer from severe thrombocytopenia during myelosuppressive treatment. To the authors' knowledge, little is known regarding the incidence of this complication or the effectiveness of possible therapies for its prevention. METHODS:In...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.22199

    authors: Meirow D,Rabinovici J,Katz D,Or R,Shufaro Y,Ben-Yehuda D

    更新日期:2006-10-01 00:00:00

  • Extracardiac rhabdomyoma: a clinicopathologic study and review of the literature.

    abstract::Extracardiac rhabdomyomas are rare benign neoplasms that in the past have been divided by histologic criteria into adult and fetal types. In this series, 15 previously unpublished cases are presented and analyzed in combination with 51 acceptable cases from the literature. The adult type of rhabdomyoma occurs almost e...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19800815)46:4<780::aid-cncr28204

    authors: Di Sant'Agnese PA,Knowles DM 2nd

    更新日期:1980-08-15 00:00:00

  • Primary retroperitoneal seminoma.

    abstract::In a retrospective review (1950-1975) of the Mayo Clinic experience with seminomas (483 cases), twelve patients (2.5%) were found to have a retroperitoneal seminoma without evidence of testicular involvement. The mean age was 47 years (range, 31-67). Eleven patients were treated by radiation alone, with doses ranging ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820501)49:9<1934::aid-cncr2820

    authors: Buskirk SJ,Evans RG,Farrow GM,Earle JD

    更新日期:1982-05-01 00:00:00

  • Activated CD4-positive T-lymphocytes and impaired cell-mediated immunity in patients with carcinoma of the urinary bladder with schistosomiasis.

    abstract::Patients with schistosomiasis of the urinary bladder (SB) associated with carcinoma of the bladder (SCB) or carcinoma of the prostate (SCP) have a variety of immunologic abnormalities, including the presence of HLA-DR+ and interleukin-2 receptor-positive (IL-2R+) T-lymphocytes in circulating blood. This study demonstr...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19900215)65:4<931::aid-cncr28206

    authors: Raziuddin S,Shetty S,Ibrahim A,Patil K

    更新日期:1990-02-15 00:00:00

  • A Phase II trial of gemcitabine for metastatic neuroendocrine tumors.

    abstract:BACKGROUND:Treatment with traditional cytotoxic chemotherapy regimens containing streptozocin or dacarbazine has resulted in only marginal benefit for patients with metastatic neuroendocrine tumors. The use of these regimens has been further limited by their potential toxicity. Gemcitabine is generally well tolerated a...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1002/cncr.20466

    authors: Kulke MH,Kim H,Clark JW,Enzinger PC,Lynch TJ,Morgan JA,Vincitore M,Michelini A,Fuchs CS

    更新日期:2004-09-01 00:00:00

  • 111Indium-bleomycin breast and axilla imaging.

    abstract::111Indium-Bleomycin (111In-Blm), a new radiopharmaceutical, was administered intravenously to 37 patients with benign and malignant breast lesions. Early and delayed images of both the breasts and axillae were made, and results were correlated with physical examination, histopathology of the excised lesion, mammograph...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197601)37:1<36::aid-cncr28203701

    authors: Silverstein MJ,Verma RC,Greenfield L,Morton DL

    更新日期:1976-01-01 00:00:00

  • Lung cancer in patients younger than 40 years of age.

    abstract::The records of 52 patients younger than 40 years of age who had bronchogenic carcinoma diagnosed between 1965 and 1985 were reviewed. The preponderance of adenocarcinoma (54%), the lower male-female ratio in this age group compared with patients age 40 or older (2:1), the importance of cigarette smoking as a causative...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19910301)67:5<1436::aid-cncr2820

    authors: Jubelirer SJ,Wilson RA

    更新日期:1991-03-01 00:00:00

  • Prognostic variables in mycosis fungoides.

    abstract::The prognostic importance of various factors was analyzed for 347 patients registered by the Mycosis Fungoides Cooperative Group (MFCG). Extent of skin involvement at the time of registration and number of sites of clinically enlarged lymph nodes were clearly the most important prognostic variables, and were combined ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810601)47:11<2671::aid-cncr282

    authors: Green SB,Byar DP,Lamberg SI

    更新日期:1981-06-01 00:00:00

  • Can immunohistochemical markers and mitotic rate improve prognostic precision in patients with primary melanoma?

    abstract:BACKGROUND:In addition to tumor thickness, several other prognostic parameters have been identified in primary human melanomas. Some are available readily (localization, gender, age, and ulceration). Others must be evaluated with a moderate or even substantial amount of work (mitoses and immunohistochemical markers). T...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/(sici)1097-0142(19990601)85:11<2391::aid-c

    authors: Ostmeier H,Fuchs B,Otto F,Mawick R,Lippold A,Krieg V,Suter L

    更新日期:1999-06-01 00:00:00

  • Type 2 diabetes mellitus and survival in pancreatic adenocarcinoma: a retrospective cohort study.

    abstract:BACKGROUND:Recent evidence has identified pre-existing type 2 diabetes mellitus (T2DM) as a risk factor for the development of PAC, but relatively little is known about its effects on survival. Our aim was to determine the effect of varying durations of pre-existing T2DM on survival in patients with PAC. METHODS:We co...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.27731

    authors: Hwang A,Narayan V,Yang YX

    更新日期:2013-01-15 00:00:00

  • Genetic studies of 457 breast cancers. Clinicopathologic parameters compared with genetic alterations.

    abstract:BACKGROUND:Human breast cancers frequently show loss of heterozygosity (LOH) and/or amplification at specific chromosomal regions. METHODS:To investigate the roles of these genetic alterations during tumor development and/or progression, 457 cases of primary breast cancer were examined for LOH at chromosomal regions 1...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19941015)74:8<2281::aid-cncr2820

    authors: Harada Y,Katagiri T,Ito I,Akiyama F,Sakamoto G,Kasumi F,Nakamura Y,Emi M

    更新日期:1994-10-15 00:00:00

  • Health-related quality of life of cancer and noncancer patients in Medicare managed care.

    abstract:BACKGROUND:Data from the Health Care Financing Administration's (HCFA) Medicare Health Outcomes Survey (MHOS) of patients enrolled in managed care services through Medicare were analyzed. The MHOS provided baseline estimates of quality of life of cancer survivors in comparison to a frequency age-matched cohort of nonca...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11085

    authors: Baker F,Haffer SC,Denniston M

    更新日期:2003-02-01 00:00:00

  • An immunohistochemical analysis for cancer of the esophagus using monoclonal antibodies specific for modified nucleosides.

    abstract:BACKGROUND:Modified nucleosides such as 1-methyl-adenosine and pseudouridine exist as minute components of transfer ribonucleic acid (tRNA) and are excreted in the urine in large amounts in the presence of malignancy. Although use of these modified nucleosides as tumor markers has long been studied and many reports hav...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19931215)72:12<3571::aid-cncr282

    authors: Masuda M,Nishihira T,Itoh K,Mizugaki M,Ishida N,Mori S

    更新日期:1993-12-15 00:00:00