An immunohistochemical analysis for cancer of the esophagus using monoclonal antibodies specific for modified nucleosides.

abstract：BACKGROUND:Little is known about genetic aberrations associated with development and progression of biliary tract carcinomas. METHODS:To study chromosomal aberrations associated with development and progression of biliary tract carcinomas, the authors used comparative genomic hybridization to examine 50 such carcinoma...

journal_title：Cancer

authors： Shiraishi K,Okita K,Harada T,Kusano N,Furui T,Kondoh S,Oga A,Kawauchi S,Fukumoto Y,Sasaki K

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:The observed seasonal and geographic variations in the incidence of immunoproliferative small intestinal disease (IPSID) suggest that environmental factors contribute to its pathogenesis. One such environmental factor, the Epstein-Barr virus (EBV), has been associated with other B-cell lymphoproliferative di...

journal_title：Cancer

authors： Baddoura FK,Unger ER,Mufarrij A,Nassar VH,Zaki SR

更新日期：1994-09-15 00:00:00

abstract：BACKGROUND:There is limited information on outcomes of prostate carcinoma treatments given to screened patient populations for whom cancer is usually detected at an earlier stage. METHODS:The authors conducted a cross-sectional evaluation of quality-of-life outcomes for men with prostate carcinoma detected in screenin...

journal_title：Cancer

authors： Smith DS,Carvalhal GF,Schneider K,Krygiel J,Yan Y,Catalona WJ

更新日期：2000-03-15 00:00:00

abstract：BACKGROUND:The clinical dose of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitro- sourea hydrochloride (ACNU) is limited by the bone marrow suppression it produces. The authors investigated whether bone marrow transplantation (BMT) associated with a high dose of ACNU could alleviate marrow toxicity ...

journal_title：Cancer

authors： Soma M,Shoin K,Yamashita J

更新日期：1993-01-15 00:00:00

abstract：:From 1959 to 1986, 24 patients with primary malignant tumors of the trachea received radiotherapy as all or part of treatment. Common presentations included respiratory symptoms in 20 patients and hemoptysis in 15. Thirteen patients had squamous carcinomas with undifferentiated and adenoid cystic cancers in five and f...

journal_title：Cancer

authors： Fields JN,Rigaud G,Emami BN

更新日期：1989-06-15 00:00:00

abstract：BACKGROUND:There is no standard therapy for surgery- and radiotherapy-resistant, recurrent, low-grade spinal cord gliomas. Therefore, a retrospective study of temozolomide (TMZ) in adults with recurrent low-grade spinal cord gliomas with a primary objective of determining progression-free survival (PFS) was performed. ...

journal_title：Cancer

authors： Chamberlain MC

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:To optimize fotemustine chemotherapy, the authors considered how to combine independent Phase II trials to predict the risk of first occurrence of severe toxicity as a function of initial patient characteristics. METHODS:Clinical data from six Phase II trials were collected. Of the 478 patients enrolled 442...

journal_title：Cancer

authors： Raymond E,Haon C,Boaziz C,Coste M

更新日期：1996-11-01 00:00:00

abstract：:Forty seven patients with early gastric cancer received a 30-minute intravenous injection of bromodeoxyuridine (BrdU), 1000 mg each 1 hour before laparotomy, to label tumor cells in the S phase. In 13 of 47 patients, specimens obtained by endoscopic biopsy were cultured in vitro at 37 degrees C for 1 hour under three ...

journal_title：Cancer

authors： Kamata T,Yonemura Y,Sugiyama K,Ooyama S,Kosaka T,Yamaguchi A,Miwa K,Miyazaki I

更新日期：1989-10-15 00:00:00

abstract：:A 48-year-old male presented with the nephrotic syndrome 3 years after resection and irradiation of a thymoma. Renal biopsy revealed membranous glomerulonephritis by electron microscopy. IgA, IgG, and C3 deposition were present in the glomerular basement membrane by immunofluorescence. There was no evidence of other a...

journal_title：Cancer

authors： Posner MR,Prout MN,Berk S

更新日期：1980-01-15 00:00:00

abstract：:Many cancer patients have elevated serum protein and sialic acid (N-acetyl neuraminic acid, NANA) levels. Serial determinations were performed, using serum treated with perchloric acid from 34 patients with widespread metastatic disease. Six of six patients who underwent debulking surgery had a drop in their serum NAN...

journal_title：Cancer

authors： Harvey HA,Lipton A,White D,Davidson E

更新日期：1981-01-15 00:00:00

abstract：BACKGROUND:In addition to tumor thickness, several other prognostic parameters have been identified in primary human melanomas. Some are available readily (localization, gender, age, and ulceration). Others must be evaluated with a moderate or even substantial amount of work (mitoses and immunohistochemical markers). T...

journal_title：Cancer

authors： Ostmeier H,Fuchs B,Otto F,Mawick R,Lippold A,Krieg V,Suter L

更新日期：1999-06-01 00:00:00

abstract：:The diagnosis of pulmonary candidiasis can only be made with certainty when tissue invasion by the organism is demonstrated histologically. In order to ascertain whether characteristic radiographic patterns are seen in patients with pulmonary candidiasis, antemortem radiographic abnormalities were correlated with auto...

journal_title：Cancer

authors： Dubois PJ,Myerowitz RL,Allen CM

更新日期：1977-09-01 00:00:00

abstract：:Forty-six examples of carcinoma cuniculatum, a rare variant of squamous cell carcinoma of the skin, were studied by means of light and electron microscopy and immunoperoxidase techniques. The tumors usually presented as ulcerated, fungating, and polypoid masses with openings of sinus tracts onto the skin surface that ...

journal_title：Cancer

authors： Kao GF,Graham JH,Helwig EB

更新日期：1982-06-01 00:00:00

abstract：:Local and systemic toxicities associated with hepatic arterial infusion of human recombinant tumor necrosis factor (rTNF) were studied in healthy adult mongrel dogs. The animals received saline containing human serum albumin with or without rTNF (0.02, 0.2, or 2.0 mg/m2). Arteriograms were made, and blood samples were...

journal_title：Cancer

authors： Ohkawa S,Wright KC,Mahajan H,Mavligit GM,Wallace S

更新日期：1989-06-01 00:00:00

abstract：:Sixty patients with advanced prostatic carcinoma were treated with monthly subcutaneous injections of a depot formulation of goserelin, a luteinizing hormone-releasing hormone (LHRH) analogue (Zoladex, ICI Pharma, Destelbergen, Belgium). All patients were regularly evaluated with measurements of luteinizing hormone (L...

journal_title：Cancer

authors： Mahler C,Verhelst J,Chaban M,Denis L

更新日期：1991-02-01 00:00:00

abstract：:After 12 cycles of MOPP therapy for Hodgkin's Disease, an adolescent black male developed hemorrhagic cystitis, which clinically and histologically was similar to that induced by cyclophosphamide. At that time he had a normal platelet count and had never been irradiated below the diaphram. The markedly contracted blad...

journal_title：Cancer

authors： Royal JE,Seeler RA

更新日期：1978-04-01 00:00:00

abstract：:The results of surgical treatment alone for 142 cases of carcinoma of the rectum and rectosigmoid from the Massachusetts General Hospital were reviewed. The incidence of local failure as any component of failure was found to be strongly dependent on the pathologic stage, and for Dukes' A was 8.0% (3/39); Dukes' B, 31%...

journal_title：Cancer

authors： Rich T,Gunderson LL,Lew R,Galdibini JJ,Cohen AM,Donaldson G

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:Initial clinic studies revealed that the overexpression of proline-directed protein kinase F(A) (PDPK F(A)) is associated conversely with various stages of tumor tissue differentiation. However, the role of overexpressed PDPK F(A) in tumor cell differentiation remains unknown and needs to be established. In ...

journal_title：Cancer

authors： Hsu CP,Yang CC,Yang SD

更新日期：2000-09-01 00:00:00

abstract：:High calcitonin levels noted on a totally healthy 49-year-old man participating in a calcitonin control project led to a presumptive diagnosis of medullary carcinoma. Complete thyroid studies augmented by selective catheterization and quantitative calcitonin studies confirmed the clinical impression of medullary carci...

journal_title：Cancer

authors： White IL,Vimadalal SD,Catz B,Van de Velde R,LaGanga T

更新日期：1981-03-15 00:00:00

abstract：:Metastatic tumors to the mucosa of the stomach are unusual occurrences that can cause clinical and pathologic problems in diagnosis. The authors report 67 cases from the files of the Veterans Administration Center at Houston. Ten cases were found on endoscopic biopsy and 57 at necropsy. Each patient endoscopically eva...

journal_title：Cancer

authors： Green LK

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Hereditary nonpolyposis colorectal cancer (HNPCC or Lynch syndrome) is an autosomal dominant disease characterized by early-onset intestinal neoplasms, localization of tumors in the proximal colon, and frequent association with cancers at other sites, especially the endometrium, skin, and stomach. The identi...

journal_title：Cancer

authors： Ponz de Leon M,Sassatelli R,Benatti P,Roncucci L

更新日期：1993-06-01 00:00:00

abstract：:The oral cavity, oropharynx and nasopharynx are readily accessible to fine needle aspiration (FNA). This study reviews the author's experience with 93 FNA from these sites: 76 from the oral cavity, eight from the oropharynx, and eight from the nasopharynx. Thirty-nine (42%) of the FNA were positive for malignancy with...

journal_title：Cancer

authors： Scher RL,Oostingh PE,Levine PA,Cantrell RW,Feldman PS

更新日期：1988-12-15 00:00:00

abstract：BACKGROUND:Evidence of racial disparities in the receipt of postmastectomy breast reconstruction is well documented. The objective of this study was to describe trends in racial disparities overall and by reconstructive technique. METHODS:The American College of Surgeons National Surgical Quality Improvement Program d...

journal_title：Cancer

authors： Epstein S,Tran BN,Cohen JB,Lin SJ,Singhal D,Lee BT

更新日期：2018-07-01 00:00:00

abstract：:Human cases autopsied at the Department of Pathology, University of Tokyo, were studied to investigate the chronologic changes in the relationship between cigarette smoking and lung cancer occurrence. The results obtained were as follows: (1) it was confirmed that the incidence of lung cancer was significantly higher ...

journal_title：Cancer

authors： Mori W,Sakai R

更新日期：1984-09-15 00:00:00

abstract：BACKGROUND:Amplification of erb-B2 and myc shows prognostic value in patients with operable breast cancer. Amplification is usually detected in tumor samples remaining after pathologic work-up, preventing the examination of small tumors. METHODS:Tumor imprints that contained low numbers of contaminating normal cells w...

journal_title：Cancer

authors： Lönn U,Lönn S,Nilsson B,Stenkvist B

更新日期：1995-06-01 00:00:00

abstract：:The clinical course of melanoma of the skin diagnosed during pregnancy was compared with a control population of women with melanoma that occurred during the childbearing years, as recorded by the Connecticut Tumor Registry. The survival at three and five years for the 12 patients whose melanoma developed during pregn...

journal_title：Cancer

authors： Houghton AN,Flannery J,Viola MV

更新日期：1981-07-15 00:00:00

abstract：BACKGROUND:There exist insufficient data characterizing patients with multiple myeloma (MM) who experienced prolonged survival. A population-based analysis of long-term survivors was conducted to investigate the roles of sociodemographic factors and upfront stem cell transplantation (SCT). METHODS:The National Cancer ...

journal_title：Cancer

authors： Hsieh RW,Go RS,Abeykoon JP,Kapoor P,Kumar SK,Gertz MA,Buadi FK,Leung N,Gonsalves WI,Kourelis TV,Warsame RM,Dispenzieri A,Lacy MQ,Kyle RA,Rajkumar SV,Paludo J

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:Bortezomib is active in heavily pretreated multiple myeloma patients; the dose-limiting toxicity is peripheral neuropathy (PN). METHODS:The authors retrospectively reviewed the incidence, severity, and risk factors for PN in 78 patients who received bortezomib. The median age was 57 years (range, 33-80 year...

journal_title：Cancer

authors： Badros A,Goloubeva O,Dalal JS,Can I,Thompson J,Rapoport AP,Heyman M,Akpek G,Fenton RG

更新日期：2007-09-01 00:00:00

abstract：:Demonstration of malignant cells in blood specimens collected during transurethral resection of the prostate (TURP) has implicated TURP in the dissemination of prostatic cancer. Of 153 patients who underwent radiation therapy for prostate cancer between January 1977 and June 1990 and were retrospectively analyzed, 93 ...

journal_title：Cancer

authors： Pansadoro V,Sternberg CN,DePaula F,Florio A,Giannarelli D,Arcangeli G

更新日期：1991-11-01 00:00:00

abstract：:Increased in vitro tetraploidy occurred in skin cultures derived from all affected patients and some family members at risk studied in families with heritable colon cancer syndromes (15 of 16 Gardner syndrome families, three Oldfield syndrome families, and four families with heritable colon cancer syndrome without pol...

journal_title：Cancer

authors： Danes BS

更新日期：1981-10-01 00:00:00