Analysis of the levels of CA125, carcinoembryonic antigen, and CA19-9 in the cervical mucus for a detection of cervical adenocarcinoma.

abstract：BACKGROUND:Although increasing rates of breast carcinoma incidence have been observed in Asian countries, appropriate strategies for detecting early stage breast carcinoma in such communities have been difficult to formulate, particularly because no large population screening trial specifically involving Asian women ha...

journal_title：Cancer

authors： Ng EH,Ng FC,Tan PH,Low SC,Chiang G,Tan KP,Seow A,Emmanuel S,Tan CH,Ho GH,Ng LT,Wilde CC

更新日期：1998-04-15 00:00:00

abstract：BACKGROUND:Germ cell tumors (GCTs) in adolescent and young males are very sensitive to cisplatin-based chemotherapy. However, 10-20% of the patients cannot be cured by currently available therapeutic options. Once a tumor does not respond to cisplatin, current therapeutic modalities offer only a chance for short pallia...

journal_title：Cancer

authors： Kollmannsberger C,Mayer F,Pressler H,Koch S,Kanz L,Oosterhuis JW,Looijenga LH,Bokemeyer C

更新日期：2002-07-15 00:00:00

abstract：BACKGROUND:Little is known about cellular level genetic alterations in preinvasive breast lesions, particularly lobular carcinoma in situ. METHODS:We employed fluorescence in situ hybridization (FISH) using pericentromeric (alpha satellite) probes to assess numerical alterations of chromosomes 1, 7, 8, 16, 17, and X i...

journal_title：Cancer

authors： Visscher DW,Wallis TL,Crissman JD

更新日期：1996-01-15 00:00:00

abstract：BACKGROUND:There are few reports comparing the clinicopathologic features of sarcomas of the aorta (SA), sarcomas of the inferior vena cava (SIVC), and sarcomas of the pulmonary artery (SPA). METHODS:The authors retrospectively reviewed 11 SA, 16 SIVC, and 16 SPA, and compared clinical, pathologic, and immunohistochem...

journal_title：Cancer

authors： Burke AP,Virmani R

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Human papillomavirus (HPV) DNA has been identified in esophageal carcinomas. However, the incidence of HPV varies significantly in different geographic locations. In the current study, neoplasms from two separate geographic regions were analyzed for the presence of HPV DNA: METHODS:One hundred and ten esoph...

journal_title：Cancer

authors： Suzuk L,Noffsinger AE,Hui YZ,Fenoglio-Preiser CM

更新日期：1996-08-15 00:00:00

abstract：BACKGROUND:As we approach the 21st century, clinically useful predictive models for prostate carcinoma are urgently needed to stratify patients reliably for future treatment strategies. Recently, many investigators have developed models that employ prostate specific antigen (PSA)-based constructs or groupings in an att...

journal_title：Cancer

authors： Movsas B,Hanlon AL,Teshima T,Hanks GE

更新日期：1997-09-15 00:00:00

abstract：BACKGROUND:This Phase III trial was performed to compare the roles of oral etoposide and intravenous (i.v.) vinblastine in the treatment of Mediterranean Kaposi's Sarcoma (MEKS) in elderly patients with severe disease (Stages II, Ac/B, III, and IV). PATIENTS AND METHODS:Sixty-five patients were randomized to receive e...

journal_title：Cancer

authors： Brambilla L,Labianca R,Boneschi V,Fossati S,Dallavalle G,Finzi AF,Luporini G

更新日期：1994-11-15 00:00:00

abstract：:The most important area in which cancer care and bioethics intersect is in the care of the dying. It is in the shift toward according more control to patients, more choice in the setting in which death will come, and in the willingness to take palliative care and comfort care seriously that bioethics has most usefully...

journal_title：Cancer

authors： Caplan AL

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:In colorectal carcinoma, venous invasion has been related to patient survival. Liver metastasis develops more frequently when venous invasion is present. However, the histologic features and clinical significance of venous invasion are not well understood. METHODS:A histologic study of venous invasion in co...

journal_title：Cancer

authors： Ouchi K,Sugawara T,Ono H,Fujiya T,Kamiyama Y,Kakugawa Y,Mikuni J,Tateno H

更新日期：1996-12-01 00:00:00

abstract：:Breast cancer tissue from 12 male patients was evaluated for the presence of estrogen receptors (ER), and at least 10 of 12 were found to be high in ER (ER+). A combination of previously published cases and our own experience indicates that 80% of patients (37/47) have ER+ tumors. This incidence of ER positivity in me...

journal_title：Cancer

authors： Friedman MA,Hoffman PG Jr,Dandolos EM,Lagios MD,Johnston WH,Siiteri PK

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Mantle cell lymphoma (MCL) is an incurable B-cell malignancy, and patients with this disease have the poorest prognosis among all patients with B-cell lymphomas. The signaling pathways that trigger MCL escape from immune surveillance are unclear. Because Toll-like receptors (TLRs) initiate innate and adaptiv...

journal_title：Cancer

authors： Wang L,Zhao Y,Qian J,Sun L,Lu Y,Li H,Li Y,Yang J,Cai Z,Yi Q

更新日期：2013-02-15 00:00:00

abstract：BACKGROUND:The degree of response and the duration of survival of patients treated with mitogen-activated protein kinase (MAPK) inhibitors are highly variable. Whether baseline clinicopathologic factors can predict the clinical course with treatment is largely unknown. METHODS:For 142 consecutive immunotherapy- and MA...

journal_title：Cancer

authors： Menzies AM,Wilmott JS,Drummond M,Lo S,Lyle M,Chan MM,Thompson JF,Guminski A,Carlino MS,Scolyer RA,Kefford RF,Long GV

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Children with diffuse brainstem glioma (BSG) commonly undergo novel therapies because their outcome is poor with radiation therapy (RT). Although recent clinical trials using new biologic agents documented intratumoral hemorrhage (IH) among several children with BSG, to the authors' knowledge little is known...

journal_title：Cancer

authors： Broniscer A,Laningham FH,Kocak M,Krasin MJ,Fouladi M,Merchant TE,Kun LE,Boyett JM,Gajjar A

更新日期：2006-03-15 00:00:00

abstract：:Epidemiologic and laboratory data suggest that cervical cancer typically arises from a series of causal steps. Each step can be studied separately in the hope of better etiologic understanding and improved cancer prevention. The earliest identified etiologic step is infection of young women with specific types of vene...

journal_title：Cancer

authors： Schiffman MH,Brinton LA

更新日期：1995-11-15 00:00:00

abstract：:Gynecologic cancers present unusual opportunities to explore the fruits of well-designed clinical trials to assess the value of existing treatment using a combined modality approach soon after diagnosis. Cancers of the ovary and uterus have well-defined, familiar natural histories. Pathways of spread are clear and rea...

journal_title：Cancer

authors： DeVita VT Jr,Wasserman TH,Young RC,Carter SK

更新日期：1976-07-01 00:00:00

abstract：:Hepatoblastoma differs from the adult type of hepatoma in clinical and pathologic features. The ratio of fucosylation of serum alpha-fetoprotein (AFP) was determined in seven patients with hepatoblastoma and in 21 infants and children with otherwise elevated serum AFP, using the improved technique of lentil agglutinin...

journal_title：Cancer

authors： Tsuchida Y,Honna T,Fukui M,Sakaguchi H,Ishiguro T

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Both paclitaxel and mitoxantrone demonstrate significant antineoplastic activity in breast cancer patients. Colony stimulating factor support allows significant dose escalation of each of these drugs when administered as a single agent. METHODS:We performed a Phase I study employing escalating doses of pacl...

journal_title：Cancer

authors： Fleming GF,Janisch L,Vogelzang NJ,Vokes EE,Ratain MJ

更新日期：1996-06-01 00:00:00

abstract：:This study delineates the temporal relationship between immune complex formation and tumor growth, and provides one possible explanation for host immunosuppression during tumor growth. The authors have studied serial circulating immune complex (CIC) levels and interleukin (IL) elaboration by peripheral blood cells (IL...

journal_title：Cancer

authors： Ravikumar T,Steele G Jr,Rodrick M,Ross D,Wilson R,Lahey S,Wright D,Munroe A,King V

更新日期：1984-03-15 00:00:00

abstract：:Twenty-one patients with bilateral Wilms' tumor are reviewed and the details of diagnosis, therapy, and survival presented. All patients had an abdominal mass at the time of diagnosis. Associated findings included hypertension, aniridia, and genitourinary anomalies. Favorable histologic features were found in all simu...

journal_title：Cancer

authors： Asch MJ,Siegel S,White L,Fonkalsrud E,Hays D,Isaacs H

更新日期：1985-11-15 00:00:00

abstract：:In 79 cases of histologically verified anaplastic giant-cell carcinoma, symptoms, treatment, and prognosis were documented. Seventy-eight patients are dead, the mean survival time being 2.5 months. One patient is cured. It was concluded that surgery and/or radiotherapy alone are not sufficient. The results from an add...

journal_title：Cancer

authors： Jereb B,Stjernswärd J,Löwhagen T

更新日期：1975-05-01 00:00:00

abstract：BACKGROUND:Two types of correction for absorbed dose (D) estimates are described for clinical applications of internal emitters. The first is appropriate for legal and scientific reasons involving phantom-based estimates; the second is patient-specific and primarily intended for radioimmunotherapy (RIT). METHODS:The M...

journal_title：Cancer

authors： Williams LE,Liu A,Yamauchi DM,Lopatin G,Raubitschek AA,Wong JY

更新日期：2002-02-15 00:00:00

abstract：BACKGROUND:The runt-related transcription factor RUNX3 plays essential roles in various types of tumors, including gastric cancer. Epigenetic changes in the methylation of the RUNX3 proximal promoter, but not common genetic changes in RUNX3, have been associated with both changes in the gene expression and development ...

journal_title：Cancer

authors： Lim B,Ju H,Kim M,Kang C

更新日期：2011-11-15 00:00:00

abstract：BACKGROUND:The primary objective of this study was to clarify the significance of p21WAF1/CIP1(p21) gene expression in the tumorgenicity of hepatitis B virus (HBV) and hepatitis C virus (HCV) infected human hepatocelluar carcinoma (HCC). METHODS:The authors performed Northern blot hybridization to compare the p21 mess...

journal_title：Cancer

authors： Kobayashi S,Matsushita K,Saigo K,Urashima T,Asano T,Hayashi H,Ochiai T

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Results from numerous trials have indicated that breast-conserving therapy (BCT) produces outcomes equivalent to those produced by mastectomy in terms of both locoregional control and survival. However, conservative treatment has resulted in the dilemma of how best to address recurrences when they appear in ...

journal_title：Cancer

authors： Vicini FA,Antonucci JV,Goldstein N,Wallace M,Kestin L,Krauss D,Kunzmann J,Gilbert S,Schell S

更新日期：2007-04-01 00:00:00

abstract：METHODS:Twelve patients with advanced epithelial nonadenocarcinoma of the paranasal sinuses and nasal fossa were treated with three cycles of cisplatin (100 mg/m2, day 1) and 5-fluorouracil (1000 mg/m2/24 hours on days 1-5 by continuous infusion), followed by preoperative external radiation therapy of 48 Gy and limited...

journal_title：Cancer

authors： Björk-Eriksson T,Mercke C,Petruson B,Ekholm S

更新日期：1992-12-01 00:00:00

abstract：:Cases of childhood cancer (less than 15 years of age at diagnosis), diagnosed between 1960 and 1984, were obtained from the Hawaii Tumor Registry, a population-based Surveillance, Epidemiology, and End Results (SEER) participant covering the entire State of Hawaii. During the 25 years of data collection, cancer was di...

journal_title：Cancer

authors： Goodman MT,Yoshizawa CN,Kolonel LN

更新日期：1989-10-15 00:00:00

abstract：BACKGROUND:In a recently reported, randomized trial, it was found that a regimen of irinotecan once every 3 weeks for patients with advanced colorectal carcinoma was associated with a lower incidence of severe diarrhea compared with weekly treatment, and both regimens had similar efficacy. METHODS:Resource utilization...

journal_title：Cancer

authors： Earle CC,Kwok A,Gazelle GS,Fuchs CS

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) tests are commonly used to assess human epidermal growth factor 2 (HER2) status of tumors in patients with breast cancer. This analysis evaluates the likely cost-effectiveness of expanded retesting to assess HER2 tumor status in women w...

journal_title：Cancer

authors： Garrison LP Jr,Lalla D,Brammer M,Babigumira JB,Wang B,Perez EA

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Preclinical studies have demonstrated that the inhibition of the PI3K/Akt/mTOR pathway restores gefitinib sensitivity in resistant cancer cell lines. A phase 1 study was conducted of the combination of everolimus, an mTOR inhibitor, and gefitinib to determine a daily dose of everolimus with gefitinib in pati...

journal_title：Cancer

authors： Milton DT,Riely GJ,Azzoli CG,Gomez JE,Heelan RT,Kris MG,Krug LM,Pao W,Pizzo B,Rizvi NA,Miller VA

更新日期：2007-08-01 00:00:00

abstract：:Various dose-time treatment plans have been used to obtain long duration pain relief in patients with metastatic bone disease. Very little has appeared in the literature evaluating the relationship of dose and fractionation to initial, delayed and permanent bone pain relief. At the Swedish Hospital Tumor Institute, 15...

journal_title：Cancer

authors： Allen KL,Johnson TW,Hibbs GG

更新日期：1976-02-01 00:00:00