Assessing the potential cost-effectiveness of retesting IHC0, IHC1+, or FISH-negative early stage breast cancer patients for HER2 status.

abstract：BACKGROUND:Intralesional radioimmunotherapy (RAIT) may improve the management of malignant gliomas whose prognosis is, at present, very poor. Current treatment modalities (e.g., surgery, radiotherapy, and chemotherapy) may prolong survival by a few months but cannot prevent tumor recurrence. METHODS:Following one or m...

journal_title：Cancer

authors： Riva P,Arista A,Tison V,Sturiale C,Franceschi G,Spinelli A,Riva N,Casi M,Moscatelli G,Frattarelli M

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:The objective of the current study was to examine the impact of adherence to guidelines on stage-specific survival outcomes in patients with stage III and high-risk stage II colon cancer. The National Comprehensive Cancer Network (NCCN) has established working, expert consensus, and evidence-based guidelines...

journal_title：Cancer

authors： Boland GM,Chang GJ,Haynes AB,Chiang YJ,Chagpar R,Xing Y,Hu CY,Feig BW,You YN,Cormier JN

更新日期：2013-04-15 00:00:00

abstract：BACKGROUND:In addition to tumor thickness, several other prognostic parameters have been identified in primary human melanomas. Some are available readily (localization, gender, age, and ulceration). Others must be evaluated with a moderate or even substantial amount of work (mitoses and immunohistochemical markers). T...

journal_title：Cancer

authors： Ostmeier H,Fuchs B,Otto F,Mawick R,Lippold A,Krieg V,Suter L

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Aberrant expression of the facilitative glucose transporter, GLUT1, is found in a wide spectrum of epithelial malignancies. The current study describes an immunohistochemical study of GLUT1 expression in benign, hyperplastic, and malignant endometrial epithelia. METHODS:One hundred sixteen formalin fixed, p...

journal_title：Cancer

authors： Wang BY,Kalir T,Sabo E,Sherman DE,Cohen C,Burstein DE

更新日期：2000-06-15 00:00:00

abstract：:The use of prostate-specific antigen (PSA) as a screening test remains controversial. There have been several attempts to refine PSA measurements to improve its predictive value. These modifications, including PSA density, PSA kinetics, and the measurement of PSA isoforms, have met with limited success. Therefore, com...

journal_title：Cancer

authors： Herman MP,Dorsey P,John M,Patel N,Leung R,Tewari A

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:In a previous clinical trial, the authors disclosed that the expression of tumor cell motility factor gp78hAMFR correlates with tumor progression in patients with bladder carcinoma. This study was initiated to evaluate whether the combination of cytostatic drugs with an antimotility factor has an effect on c...

journal_title：Cancer

authors： Otto T,Bex A,Krege S,Walz PH,Rübben H

更新日期：1997-08-01 00:00:00

abstract：:Two patients fulfilled the clinical and hematologic criteria for B-cell acute lymphoblastic leukemia: the malignant cells had L3 morphology, bore B-cell markers, and carried the specific t(8;14) translocation. The leukemic cells of one patient were tetrasomic for 1q, and those of the other patient showed several separ...

journal_title：Cancer

authors： Morris CM,Fitzgerald PH,Neville MA,Wyld PJ,Beard ME

更新日期：1984-07-01 00:00:00

abstract：:The records of all 27 adult patients (age, greater than or equal to 16 years) diagnosed with cerebellar medulloblastoma between 1968 and 1986 were reviewed. Twenty-four patients (89%) were treated with postoperative megavoltage irradiation. Twenty of these patients underwent craniospinal irradiation. Sixteen patients ...

journal_title：Cancer

authors： Hazuka MB,DeBiose DA,Henderson RH,Kinzie JJ

更新日期：1992-04-15 00:00:00

abstract：:One hundred and sixty-two cases of Stage IA microinvasive carcinoma of the cervix are presented. These patients represent the combined experience at the University of Miami School of Medicine, Miami, Florida, and Downstate Medical Center, Brooklyn, New York. The criteria used in both institutions are 1) penetration of...

journal_title：Cancer

authors： Averette HE,Nelson JH Jr,Ng AB,Hoskins WJ,Boyce JG,Ford JH Jr

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to confirm whether black and white women with endometrial cancer are equally tolerant of chemotherapy and identify factors that impact survival. METHODS:A retrospective review of 169 black women and 982 white women with the International Federation of Gynecologists and Obstetri...

journal_title：Cancer

authors： Farley JH,Tian C,Rose GS,Brown CL,Birrer M,Risinger JI,Thigpen JT,Fleming GF,Gallion HH,Maxwell GL

更新日期：2010-01-15 00:00:00

abstract：:Carcinomas of the pancreas with giant cells are not rare, but those containing osteoclast-like tumor cells are quite unusual. This report documents a pancreatic neoplasm comprising both easily recognizable well-differentiated adenocarcinoma and osteoclast-like tumor. The literature on the "osteoclastoma" of the pancre...

journal_title：Cancer

authors： Trepeta RW,Mathur B,Lagin S,LiVolsi VA

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:Retrospective studies suggest that dose intensity is an important determinant of outcome in the treatment of patients with a variety of malignant diseases such as breast cancer, ovarian cancer, and lymphoma. Unfortunately, these results have not been clearly substantiated in prospective randomized trials. On...

journal_title：Cancer

authors： Long GD,Negrin RS,Hoyle CF,Kusnierz-Glaz CR,Schriber JR,Blume KG,Chao NJ

更新日期：1995-09-01 00:00:00

abstract：:A 52-year-old female presented with an extensive retroperitoneal sarcoma and intraluminal inferior vena caval extension. Presumably during resection, embolization of a tumor fragment occurred to the right pulmonary hilum. The patient was asymptomatic for 16 months until a right hilar mass developed on a follow-up ches...

journal_title：Cancer

authors： Arbeit JM,Flye MW,Mundinger GH Jr,Webber BL

更新日期：1980-09-15 00:00:00

abstract：BACKGROUND:Although pediatric cancer mortality and survival have improved in the United States over the past 40 years, differences exist by age, race/ethnicity, cancer site, and economic status. To assess progress, this study examined recent mortality and survival data for individuals younger than 20 years. METHODS:Ag...

journal_title：Cancer

authors： Siegel DA,Richardson LC,Henley SJ,Wilson RJ,Dowling NF,Weir HK,Tai EW,Buchanan Lunsford N

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:The authors previously identified sperm protein 17 (Sp17) as being expressed in patients with multiple myeloma. The restricted expression of Sp17 in normal tissue makes it an ideal target for tumor vaccine. In the current study, the authors extended their research to include ovarian carcinoma. METHODS:A pai...

journal_title：Cancer

authors： Chiriva-Internati M,Wang Z,Salati E,Timmins P,Lim SH

更新日期：2002-05-01 00:00:00

abstract：:The two cancers specific to women for which substantial research on their relationship to exogenous estrogens has been reported are endometrial cancer and breast cancer. With the former, the link to estrogen use is well established. The estrogen use patterns associated with increased risk of endometrial cancer are cha...

journal_title：Cancer

authors： Hulka BS

更新日期：1987-10-15 00:00:00

abstract：:In nine patients who had undergone trans-sphenoidal hypophysectomy, prolactin dynamics were studied with intravenous thyrotropin releasing hormone (TRH). Residual prolactin secretory reserve was demonstrated in seven. Five patients were TRH tested both before and after trans-sphenoidal hypophysectomy. Hypophysectomy d...

journal_title：Cancer

authors： McMillin JM,Seal US,Theologides A

更新日期：1977-05-01 00:00:00

abstract：:Local and systemic toxicities associated with hepatic arterial infusion of human recombinant tumor necrosis factor (rTNF) were studied in healthy adult mongrel dogs. The animals received saline containing human serum albumin with or without rTNF (0.02, 0.2, or 2.0 mg/m2). Arteriograms were made, and blood samples were...

journal_title：Cancer

authors： Ohkawa S,Wright KC,Mahajan H,Mavligit GM,Wallace S

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:A 59-year-old male developed intractable hiccups during monthly therapy with high dose dexamethasone for multiple myeloma. Hiccups would begin hours after his first dose and continue over the 4 days of therapy. He sought assistance after his attempt at home remedies failed and the hiccups became exhausting. ...

journal_title：Cancer

authors： Cersosimo RJ,Brophy MT

更新日期：1998-01-15 00:00:00

abstract：:The clinicopathologic significance of mucus production by adenocarcinoma of the colon and rectum was analyzed in retrospective study with stage matched non-mucus producing control carcinomas. Mucinous carcinoma of the colon and rectum comprised 132 (15%) of 893 cases of colorectal carcinoma. The rectum was the most co...

journal_title：Cancer

authors： Symonds DA,Vickery AL

更新日期：1976-04-01 00:00:00

abstract：BACKGROUND:As we approach the 21st century, clinically useful predictive models for prostate carcinoma are urgently needed to stratify patients reliably for future treatment strategies. Recently, many investigators have developed models that employ prostate specific antigen (PSA)-based constructs or groupings in an att...

journal_title：Cancer

authors： Movsas B,Hanlon AL,Teshima T,Hanks GE

更新日期：1997-09-15 00:00:00

abstract：BACKGROUND:Recommendations for pretreatment evaluation and treatment of cervical cancer have significantly evolved over the last decade because of the results of multiple randomized studies comparing the addition of platin-based chemoradiation as well as the widespread dissemination and use of imaging modalities. This ...

journal_title：Cancer

authors： Trimble EL,Harlan LC,Gius D,Stevens J,Schwartz SM

更新日期：2008-08-15 00:00:00

abstract：BACKGROUND:Hypercalcemia of malignancy (HM) is one of the commonest metabolic complications associated with cancer. Plasma parathyroid hormone-related peptide (PTH-rp) is known to cause hypercalcemia in the vast majority of patients with HM. METHODS:Fifty-two patients with HM were treated with a single infusion of 60 ...

journal_title：Cancer

authors： Wimalawansa SJ

更新日期：1994-04-15 00:00:00

abstract：:The prognostic importance of various factors was analyzed for 347 patients registered by the Mycosis Fungoides Cooperative Group (MFCG). Extent of skin involvement at the time of registration and number of sites of clinically enlarged lymph nodes were clearly the most important prognostic variables, and were combined ...

journal_title：Cancer

authors： Green SB,Byar DP,Lamberg SI

更新日期：1981-06-01 00:00:00

abstract：:Forty-two cases of sarcomatoid renal cell carcinoma were reviewed clinicopathologically. Twenty-four patients were men, and 18 women; average age was 56.2 years (range, 30-81 years). Eight, 9, 13, and 12 cases were Stages I, II, III, and IV, respectively. Three morphologic patterns of sarcomatoid components were ident...

journal_title：Cancer

authors： Ro JY,Ayala AG,Sella A,Samuels ML,Swanson DA

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Soft tissue sarcomas of the hand and foot present unique management challenges. The purpose of the current study study was to determine oncologic outcome, particularly with respect to factors affecting local recurrence, distant recurrence, and disease-specific survival. METHODS:A retrospective study was per...

journal_title：Cancer

authors： Lin PP,Guzel VB,Pisters PW,Zagars GK,Weber KL,Feig BW,Pollock RE,Yasko AW

更新日期：2002-08-15 00:00:00

abstract：BACKGROUND:Young adults have historically been the least likely to have health insurance in the United States. Previous studies of survivors of childhood cancer found lower rates of insurance and less access to medical care compared with siblings; however, to the authors' knowledge, no studies to date have examined con...

journal_title：Cancer

authors： Parsons HM,Schmidt S,Harlan LC,Kent EE,Lynch CF,Smith AW,Keegan TH,AYA HOPE Collaborative.

更新日期：2014-08-01 00:00:00

abstract：:Cardiac metastases from malignant melanoma are frequent, usually asymptomatic and occur terminally. When responsible for symptoms, close evaluation of the patient is imperative for correct diagnosis and subsequent therapy. Surgical intervention where indicated in combination with chemotherapy and judicious use of irra...

journal_title：Cancer

authors： Thomas JH,Panoussopoulos DG,Jewell WR,Pierce GE

更新日期：1977-04-01 00:00:00

abstract：BACKGROUND:African Americans are diagnosed more frequently with colorectal carcinoma at a later stage compared with Caucasians. One potential reason for the disparity is a lower rate of screening examinations. METHODS:Using Outpatient and Physician-Supplier claims for all Medicare beneficiaries age > or = 65 years in ...

journal_title：Cancer

authors： Cooper GS,Koroukian SM

更新日期：2004-01-15 00:00:00

abstract：:The long-term effect of cisplatin on renal function was studied in a follow-up investigation, 16 to 52 months after chemotherapy in 22 patients with disseminated nonseminomatous testicular cancer. The median cumulated cisplatin dose was 452 mg/m2 (range, 275-650 mg/m2). Prehydration with isotonic saline secured diures...

journal_title：Cancer

authors： Fjeldborg P,Sørensen J,Helkjaer PE

更新日期：1986-11-15 00:00:00