Primary seminoma of the mediastinum. Cancer Control Agency of British Columbia experience.

abstract：BACKGROUND:The objective of this study was to describe characteristics at diagnosis and outcomes of adults with soft tissue sarcoma. METHODS:The authors conducted a retrospective multicenter study of 12,262 patients who were treated between January 1980 and 31 December 2013 in French Sarcoma Group centers and enrolled...

journal_title：Cancer

authors： Penel N,Coindre JM,Giraud A,Terrier P,Ranchere-Vince D,Collin F,Guellec SLE,Bazille C,Lae M,de Pinieux G,Ray-Coquard IL,Bonvalot S,Cesne ALE,Robin YM,Stoeckle E,Toulmonde M,Blay JY

更新日期：2018-03-15 00:00:00

abstract：:In view of the rarity of small-bowel epithelial neoplasms as compared with the case for the large bowel, evidence for an adenoma-carcinoma sequence in the small bowel was studied based on a search for data in the medical literature for the years 1927 through 1986. Sufficiently defined data were found for comparison of...

journal_title：Cancer

authors： Sellner F

更新日期：1990-08-15 00:00:00

abstract：BACKGROUND:American Indians and Alaska Natives (AI/AN) experience higher morbidity and mortality from primary liver cancer than other United States (US) populations, but racial misclassification in medical records results in underestimates of disease burden. METHODS:To reduce misclassification, National Program of Can...

journal_title：Cancer

authors： Jim MA,Perdue DG,Richardson LC,Espey DK,Redd JT,Martin HJ,Kwong SL,Kelly JJ,Henderson JA,Ahmed F

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Postgastrectomy patients undergoing chemoradiation risk chemoradiation-induced liver disease (CRILD). The objectives of this study were to investigate dosimetric implications and assess biologic susceptibility to CRILD in these patients. METHODS:Sixty-two patients with Stage IB-IV gastric/gastroesophageal a...

journal_title：Cancer

authors： Cheng JC,Liu MC,Tsai SY,Fang WT,Jer-Min Jian J,Sung JL

更新日期：2004-11-01 00:00:00

abstract：:This article describes the clinicopathologic features of six cases of uterine papillary serous carcinoma (UPSC), which developed several years after radiation therapy (RT) for cervical carcinoma. The possible etiologic role of radiation is discussed, and the literature on endometrial carcinomas developing after RT is ...

journal_title：Cancer

authors： Parkash V,Carcangiu ML

更新日期：1992-01-15 00:00:00

abstract：:Two children with cancer that persisted after multiple exploratory laparotomies, external beam radiation therapy, and multidrug chemotherapy had gold 198 (198Au) seeds implanted into their localized but unresectable tumor. Both children are alive, are receiving no therapy, and are disease-free more than 2 years later....

journal_title：Cancer

authors： Knight PJ,Doornbos JF,Rosen D,Lin JJ,Farha GJ

更新日期：1986-03-01 00:00:00

abstract：:We report on an 89-year-old female admitted with signs of intestinal obstruction in whom three independent adenocarcinomas of the proximal jejunum were found. Multiple foci of pyloric gland metaplasia, glandular hyperplasia and dysplasia, carcinoma-in-situ, and several varieties of adenocarcinoma were identified on mi...

journal_title：Cancer

authors： Warner TF,Peralta J

更新日期：1979-09-01 00:00:00

abstract：:The current results of trials testing combined surgery and chemotherapy in patients with breast cancer is reviewed. Information concerning eight trials utilizing nine single-agent regimens was obtained. The results at this time are conflicting. There appear to be differences among the regimens utilized in the various ...

journal_title：Cancer

authors： Tormey DC

更新日期：1975-09-01 00:00:00

abstract：BACKGROUND:Some studies have suggested that the use of calcium channel blockers may increase the risk of cancer. A possible association of the use of calcium channel blockers with cancer incidence and cancer mortality was addressed using data from the Nurses' Health Study. METHODS:In this study, a total of 18,635 fema...

journal_title：Cancer

authors： Michels KB,Rosner BA,Walker AM,Stampfer MJ,Manson JE,Colditz GA,Hennekens CH,Willett WC

更新日期：1998-11-01 00:00:00

abstract：:The prognostic significance of objectively measured karyometric variables (ploidy pattern, nuclear roundness, area, elongation, chromatin texture, and nearest nucleus distance) was investigated in relation to clinical (stage and type of disease) and morphologic (histologic patterns) variables in 27 patients with the d...

journal_title：Cancer

authors： Galera-Davidson H,González-Cámpora R,Mora-Marín JA,Matilla-Vincente A,Dytch HE,Bartels PH,Lerma-Puertas E,Andrada-Becerra E,Bibbo M

更新日期：1990-05-15 00:00:00

abstract：BACKGROUND:Recent advances in the early detection of prostatic adenocarcinoma have stimulated interest in the development of techniques for determining metastatic potential. METHODS:One hundred cases of adenocarcinoma, including 66 biopsy and radical prostatectomy specimens; 20 biopsies alone; and 14 transurethral res...

journal_title：Cancer

authors： Ross JS,Nazeer T,Church K,Amato C,Figge H,Rifkin MD,Fisher HA

更新日期：1993-11-15 00:00:00

abstract：BACKGROUND:The authors evaluated the two indicators of metastatic proclivity (namely, virulence [V; the rate of appearance of distant metastases] and metastagenicity [M; the ultimate likelihood of developing distant metastases]) of breast carcinoma in elderly women. The authors then compared these characteristics with ...

journal_title：Cancer

authors： Singh R,Hellman S,Heimann R

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:For this report, the authors comprehensively summarized the existing literature on patients with pineoblastoma and identified the variables and treatments that had an impact patient on outcomes. METHODS:A comprehensive search identified 109 studies that collectively described the outcomes of patients with p...

journal_title：Cancer

authors： Tate M,Sughrue ME,Rutkowski MJ,Kane AJ,Aranda D,McClinton L,McClinton L,Barani IJ,Parsa AT

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:External beam radiation therapy (EBRT) for rectal cancer unavoidably delivers significant radiation dose to the prostate gland. The effect of this incidental exposure on subsequent prostate cancer diagnosis was investigated using the Surveillance, Epidemiology, and End Results (SEER) cancer registry. METHOD...

journal_title：Cancer

authors： Hoffman KE,Hong TS,Zietman AL,Russell AH

更新日期：2008-02-15 00:00:00

abstract：BACKGROUND:Human papillomaviruses (HPVs) commonly cause proliferative lesions of squamous epithelia, and infection with certain HPV types carries a high risk of malignant transformation, especially in the uterine cervix but also at other sites, including the esophagus. We used molecular techniques to detect and type HP...

journal_title：Cancer

authors： West AB,Soloway GN,Lizarraga G,Tyrrell L,Longley JB

更新日期：1996-06-15 00:00:00

abstract：BACKGROUND:The authors compared the relative efficacy and safety of low-molecular-weight heparin (LMWH) and unfractionated heparin (UFH) for the initial treatment of venous thromboembolism (VTE) between patients with and without cancer. METHODS:By using Cochrane methodology for systematic reviews, separate meta-analys...

journal_title：Cancer

authors： Akl EA,Rohilla S,Barba M,Sperati F,Terrenato I,Muti P,Bdair F,Schünemann HJ

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Leptomeningeal carcinomatosis (LC) represents a devastating complication of systemic cancer, and patients with LC have a dismal prognosis and increased mortality. The few studies that have focused on the evaluation of prognostic factors in patients with LC have resulted in contradictory results. Thus, the tr...

journal_title：Cancer

authors： Bruna J,González L,Miró J,Velasco R,Gil M,Tortosa A,Neuro-Oncology Unit of the Institute of Biomedical Investigation of Bellvitge.

更新日期：2009-01-15 00:00:00

abstract：:The identification of important prognostic factors at diagnosis of childhood leukemia has been very useful in explaining the marked differences in disease outcome. After a complete remission is achieved, it is interesting to determine whether the ability to maintain a complete remission and the patient's survival cont...

journal_title：Cancer

authors： Sather H,Coccia P,Nesbit M,Level C,Hammond D

更新日期：1981-07-15 00:00:00

abstract：BACKGROUND:Microsatellite instability (MIN) appears to be a novel molecular mechanism in carcinogenesis and is believed to reflect multiple replication errors. The authors analyzed MIN in de novo acute leukemia and its association with expression of the human MSH3 (hMSH3) gene and point mutations of the N-ras gene. The...

journal_title：Cancer

authors： Tanosaki S,Inokuchi K,Shimada T,Dan K

更新日期：1998-08-01 00:00:00

abstract：:Seventy three patients with disseminated diffuse non-Hodgkin's lymphomas were treated with combinations of cyclophosphamide, vincristine sulfate, prednisone, and doxorubicin with and without 2 weekly doses of oral methotrexate in "intermediate" doses, followed by calcium leucovorin rescue. The addition of methotrexate...

journal_title：Cancer

authors： Gomez GA,Barcos M,Han T,Henderson ES

更新日期：1987-07-01 00:00:00

abstract：:In 1988, Californians passed Proposition 99, which raised the tobacco tax from 10 cents to 35 cents and allocated 20% of the resulting revenues, approximately $100 million, for tobacco education and 5% for tobacco-related research. Seventy percent was allocated for health care costs and 5% for the environment. In this...

journal_title：Cancer

authors： Martin CB,Beerline D,Breslow L

更新日期：1998-12-15 00:00:00

abstract：BACKGROUND:Gene expression profiling should be applicable to needle biopsy samples if microarray technology is to become practically useful for clinical research or management of breast carcinoma. This study compared gene expression profiles derived from fine-needle aspiration biopsy (FNAB) and from core needle biopsy ...

journal_title：Cancer

authors： Symmans WF,Ayers M,Clark EA,Stec J,Hess KR,Sneige N,Buchholz TA,Krishnamurthy S,Ibrahim NK,Buzdar AU,Theriault RL,Rosales MF,Thomas ES,Gwyn KM,Green MC,Syed AR,Hortobagyi GN,Pusztai L

更新日期：2003-06-15 00:00:00

abstract：BACKGROUND:Current salvage therapy for recurrent high-risk neuroblastoma is rarely curative. Assessment of the effectiveness of new, primarily cytostatic agents requires the redefinition of study endpoints to reflect disease stabilization rather than tumor response or regression. The intervals of disease control in the...

journal_title：Cancer

authors： Santana VM,Furman WL,McGregor LM,Billups CA

更新日期：2008-06-15 00:00:00

abstract：:Peritoneal mesothelioma in a 61-year-old man, occurred 26 years after abdominal radiotherapy for a testicular seminoma. The patient had no history of asbestos exposure. After asbestos, radiation is the second most frequent defined cause of mesothelioma in North America, but the number of well-documented cases is small...

journal_title：Cancer

authors： Gilks B,Hegedus C,Freeman H,Fratkin L,Churg A

更新日期：1988-05-15 00:00:00

abstract：:Head and neck cancer (H&N CA) patients have known depression of cell-mediated immunity. There is suggestive evidence that prostaglandin (PGE2)-secreting cells may be a major factor. The authors have sought to determine the role of PGE2-releasing monocytes-macrophages in this immune depression by determining the effect...

journal_title：Cancer

authors： Wanebo HJ,Riley T,Katz D,Pace RC,Johns ME,Cantrell RW

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:RAS/RAF/mitogen-activated protein kinase activation is common in myeloid malignancies. Trametinib, a mitogen-activated protein kinase kinase 1 (MEK1)/MEK2 inhibitor with activity against multiple myeloid cell lines at low nanomolar concentrations, was evaluated for safety and clinical activity in patients wi...

journal_title：Cancer

authors： Borthakur G,Popplewell L,Boyiadzis M,Foran J,Platzbecker U,Vey N,Walter RB,Olin R,Raza A,Giagounidis A,Al-Kali A,Jabbour E,Kadia T,Garcia-Manero G,Bauman JW,Wu Y,Liu Y,Schramek D,Cox DS,Wissel P,Kantarjian H

更新日期：2016-06-15 00:00:00

abstract：BACKGROUND:There is controversy regarding the optimal management of thyroid cancer. The proportion of patients with low-risk thyroid cancer who received radioactive iodine (RAI) treatment increased over the last 20 years, and little is known about the role played by clinicians in hospital-level RAI use for low-risk dis...

journal_title：Cancer

authors： Haymart MR,Banerjee M,Yang D,Stewart AK,Koenig RJ,Griggs JJ

更新日期：2013-01-15 00:00:00

abstract：:The livers of 345 autopsy cases of chronic liver disease were examined for macroregenerative nodule (MRN), a large nodular lesion more than 10 mm in diameter. A total of 86 lesions of MRN was found in 49 cases (14.2%): 32 were from 191 cases of hepatocellular carcinoma (HCC), 16 were from 148 cases of cirrhosis only, ...

journal_title：Cancer

authors： Furuya K,Nakamura M,Yamamoto Y,Togei K,Otsuka H

更新日期：1988-01-01 00:00:00

abstract：:High calcitonin levels noted on a totally healthy 49-year-old man participating in a calcitonin control project led to a presumptive diagnosis of medullary carcinoma. Complete thyroid studies augmented by selective catheterization and quantitative calcitonin studies confirmed the clinical impression of medullary carci...

journal_title：Cancer

authors： White IL,Vimadalal SD,Catz B,Van de Velde R,LaGanga T

更新日期：1981-03-15 00:00:00

abstract：BACKGROUND:This study was performed to develop a sensitive method for the detection of circulating hepatocellular carcinoma (HCC) cells in peripheral blood, in advance of the diagnosis of distant metastasis of HCC by conventional means. METHODS:Peripheral blood (5 ml) samples were obtained from 64 patients with HCC an...

journal_title：Cancer

authors： Komeda T,Fukuda Y,Sando T,Kita R,Furukawa M,Nishida N,Amenomori M,Nakao K

更新日期：1995-05-01 00:00:00