Type 73 human papillomavirus in esophageal squamous cell carcinoma: a novel association.

abstract：BACKGROUND:p53 gene mutation and p53 protein accumulation are common in human cancer. However, their clinical significance is controversial and p53 accumulation may not correlate with gene mutation. The current study investigates the occurrence of p53 alterations in esophageal carcinoma, the correlation between the ana...

journal_title：Cancer

authors： Coggi G,Bosari S,Roncalli M,Graziani D,Bossi P,Viale G,Buffa R,Ferrero S,Piazza M,Blandamura S,Segalin A,Bonavina L,Peracchia A

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Many studies have tried to identify prognostic factors to guide the selection of patients at high risk for metastases in penile carcinoma. The authors evaluated human papillomavirus (HPV) status with respect to clinical features, incidence of metastases, and prognosis of penile carcinoma. METHODS:Human papi...

journal_title：Cancer

authors： Bezerra AL,Lopes A,Santiago GH,Ribeiro KC,Latorre MR,Villa LL

更新日期：2001-06-15 00:00:00

abstract：BACKGROUND:Neovascularization reportedly is correlated with metastasis, recurrence, and prognosis in some types of tumors. Microvessel quantification in so-called "hot spots" has been studied extensively as the only factor reflecting angiogenesis in various malignant tumors. The objective of this report was to evaluate...

journal_title：Cancer

authors： Pavlopoulos PM,Konstantinidou AE,Agapitos E,Kavantzas N,Nikolopoulou P,Davaris P

更新日期：1998-11-15 00:00:00

abstract：BACKGROUND:Hypoxia inducible factor-1 (HIF-1) plays a critical role in angiogenesis during vascular development. The authors tested the hypothesis that HIF-1 expression correlates with progression and angiogenesis in brain tumors. METHODS:The authors investigated the expression of the HIF-1alpha and HIF-1beta subunits...

journal_title：Cancer

authors： Zagzag D,Zhong H,Scalzitti JM,Laughner E,Simons JW,Semenza GL

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:The purpose of the current study was to examine patient selection for an aromatase inhibitor in breast cancer patients who were free from adverse events 5 years after treatment with tamoxifen. METHODS:In all, 471 women were treated with breast-conserving surgery, axillary lymph node dissection, and radiatio...

journal_title：Cancer

authors： Freedman GM,Anderson P,Li T,Ross E,Swaby R,Goldstein L

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Interferon is approved for adjuvant treatment of patients with stage IIB/III melanoma. The identification of predictive markers that would permit selection of patients would be beneficial. Specific human leukocyte antigen (HLA) class I and II antigens have previously shown an association with response to the...

journal_title：Cancer

authors： Gogas H,Kirkwood JM,Falk CS,Dafni U,Sondak VK,Tsoutsos D,Stratigos A,Markopoulos C,Pectasides D,Spyropoulou-Vlachou M

更新日期：2010-09-15 00:00:00

abstract：:Pancreatic carcinomas have been induced in Wistar and W/LEW rats by administration of total azaserine doses of 150-520 mg/kg by injection or oral routes over periods of 5-52 weeks. The latent period for development of invasive carcinomas was 1-2 years, but focal abnormalities in acinar cells appear earlier. The incide...

journal_title：Cancer

authors： Longnecker DS,Roebuck BD,Yager JD Jr,Lilja HS,Siegmund B

更新日期：1981-03-15 00:00:00

abstract：BACKGROUND:Despite Helicobacter pylori (HP) eradication, individuals can still develop gastric cancer (GC). Prior studies have demonstrated that nonaspirin nonsteroidal anti-inflammatory drugs (NA-NSAIDs) reduce the risk of GC, but this may be caused by immortal time bias and failure to adjust for HP status. The object...

journal_title：Cancer

authors： Li B,Cheung KS,Wong IY,Leung WK,Law S

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:The prognostic significance of molecular phenotype in breast cancer is well established in the literature. Recent studies have demonstrated that subgross lesion distribution (unifocal, multifocal, and diffuse) and disease extent also carry prognostic significance in this disease. However, the correlation of ...

journal_title：Cancer

authors： Pekar G,Hofmeyer S,Tabár L,Tarján M,Chen TH,Yen AM,Chiu SY,Hellberg D,Gere M,Tot T

更新日期：2013-03-15 00:00:00

abstract：:This clinicopathologic study concerns 27 cases of "dedifferentiated" soft tissue sarcoma (DSTS), including 14 liposarcomas, six leiomyosarcomas, five chondrosarcomas, and two rhabdomyosarcomas. In addition, the authors conducted an immunohistochemical survey of 23 cases and an electron microscopic examination of three...

journal_title：Cancer

authors： Hashimoto H,Daimaru Y,Tsuneyoshi M,Enjoji M

更新日期：1990-10-01 00:00:00

abstract：:Forty-one previously untreated patients with a diagnosis of acute myelogenous leukemia (AML) were entered on a study using early intensification followed by a short-term maintenance chemotherapy. Induction and early intensification consisted of three to four cycles of doxorubicin, vincristine, cytosine arabinoside (Ar...

journal_title：Cancer

authors： Kantarjian HM,Keating MJ,Walters RS,McCredie KB,Bodey GP,Freireich EJ

更新日期：1986-10-15 00:00:00

abstract：BACKGROUND:Uveal melanomas of the choroid and ciliary body are aggressive tumors causing the death of approximately 50% of patients. In contrast, iris melanomas only infrequently metastasize; why these differences exist is not known. The local environment can regulate cancer growth and development, and it is probable t...

journal_title：Cancer

authors： Canovas D,Rennie IG,Nichols CE,Sisley K

更新日期：2008-04-15 00:00:00

abstract：BACKGROUND AND METHODS:Predictors of distant relapse following conservative surgery for breast cancer were studied in a review of 425 women. Five steps of breast cancer patient management were defined in which increasing amounts of information, potentially relevant to prognosis for metastasis-free survival (MFS), were ...

journal_title：Cancer

authors： Tubiana-Hulin M,Le Doussal V,Hacene K,Rouëssé J,Brunet M

更新日期：1993-08-15 00:00:00

abstract：:In a cohort of 254,417 male Swedish farmers (4,330,717 person-years) the incidence of cancer of the respiratory organs was compared to a reference cohort of 1,725,845 men (30,131,664 person-years) employed in other economic activities than agriculture or forestry. In the study cohort 1450 cases of cancer in the respir...

journal_title：Cancer

authors： Wiklund K,Steineck G

更新日期：1988-03-01 00:00:00

abstract：:To investigate the utility of thallium 201 (Tl-201) thyroid scintigraphy for the detection of thyroid malignancies, early and delayed Tl-201 scintigraphy was done in 70 consecutive patients with a clinically solitary cold (Iodine 123 [I-123]) nodule. Early Tl-201 scintigraphy had a sensitivity of 100% and a specificit...

journal_title：Cancer

authors： Bleichrodt RP,Vermey A,Piers DA,de Langen ZJ

更新日期：1987-12-01 00:00:00

abstract：:Formal cancer survivorship care is a growing focus internationally. This article provides a broad overview of the national strategies currently in progress for the development of survivorship programs and care plans within the United States and across Europe. The different approaches taken in their implementation, sta...

journal_title：Cancer

authors： McCabe MS,Faithfull S,Makin W,Wengstrom Y

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Although the biologic characteristics of papillary cystic tumors (PCT) generally indicate a good prognosis, a malignant form has been reported. METHODS:Twenty-two examples of PCT were examined to assess their malignant potential by histologic, flow cytometric, and immunohistochemical studies. RESULTS:Three...

journal_title：Cancer

authors： Nishihara K,Nagoshi M,Tsuneyoshi M,Yamaguchi K,Hayashi I

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:Childhood cancer survivors have been reported to be vulnerable to psychiatric morbidities and risky health behavior. Suicides, substance abuse, accidents, and violence as causes of death can be regarded as an extreme manifestation of risky health behavior. In the current study, the authors studied the risk o...

journal_title：Cancer

authors： Korhonen LM,Taskinen M,Rantanen M,Erdmann F,Winther JF,Bautz A,Feychting M,Mogensen H,Talbäck M,Malila N,Ryynänen H,Madanat-Harjuoja L

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:The incidence, risk factors, time course, and impact on survival of venous thromboembolism (VTE) in a large, population-based study of patients with bladder cancer have not been identified previously. METHODS:The California Cancer Registry was merged with the California Patient Discharge Data Set to determi...

journal_title：Cancer

authors： Sandhu R,Pan CX,Wun T,Harvey D,Zhou H,White RH,Chew HK

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Reduced melanoma risk has been reported with regular use of nonsteroidal anti-inflammatory drugs (NSAIDs). However, the ability of NSAIDs to reach melanocytes in vivo and modulate key biomarkers in preneoplastic lesions such as atypical nevi has not been evaluated. METHODS:This randomized, double-blind, pla...

journal_title：Cancer

authors： Curiel-Lewandrowski C,Swetter SM,Einspahr JG,Hsu CH,Nagle R,Sagerman P,Tangrea J,Parnes H,Alberts DS,Chow HH

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:The frequency of mutant p53 in bone marrow metastases of patients with carcinoma of the prostate (CaP) and in matched sets of metastatic and primary lesions from the same patients was investigated. The data were examined in relation to prior treatment with androgen ablation (AA) therapy and were compared wit...

journal_title：Cancer

authors： Meyers FJ,Gumerlock PH,Chi SG,Borchers H,Deitch AD,deVere White RW

更新日期：1998-12-15 00:00:00

abstract：BACKGROUND:Although there is no doubt that bisphosphonates (BPs), specific inhibitors of osteoclasts, are beneficial for the treatment of bone metastases, their effects on visceral metastases are unclear. The effect of zoledronic acid (ZOL) was examined in vivo on lung metastasis progression and animal survival, and in...

journal_title：Cancer

authors： Ory B,Heymann MF,Kamijo A,Gouin F,Heymann D,Redini F

更新日期：2005-12-01 00:00:00

abstract：:Acid phosphatase activity biochemically in the primary tumor of 20 patients with prostatic carcinoma, was studied in an attempt to understand the basis for a correlation or lack of correlation between serum and/or bone marrow acid phosphatase levels and the presence and/or clinical behavior of prostatic carcinoma. The...

journal_title：Cancer

authors： Copland GT,Whitehurst GB,Pretlow TP,Boohaker EA,Bartolucci AA,Pretlow TG 2nd

更新日期：1983-07-01 00:00:00

abstract：:A primitive neuroectodermal tumor of peripheral nerve origin was examined by light and electron microscopy. The lesion arose in association with the S1 nerve root of the lumbosacral plexus in a 22-year-old female. Following a surgical biopsy, the patient received systemic chemotherapy; however, approximately one-and-a...

journal_title：Cancer

authors： Bolen JW,Thorning D

更新日期：1980-12-01 00:00:00

abstract：:An unusual case of myeloproliferative disorder in which mature and immature myeloid cells were found to contain unusual cytoplasmic inclusions is reported. By light microscopy, these inclusions could be observed with Wright's stain. By electron microscopy they appeared to consist of a pale, finely granular material wi...

journal_title：Cancer

authors： Coppola A,O'Connor J

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:The importance of the bone marrow microenvironment in multiple myeloma is receiving increasing attention. Recent studies have suggested the importance of cytokine production and cell-cell contact by bone marrow stromal cells in the survival of myeloma cells. METHODS:In the current study, the authors examine...

journal_title：Cancer

authors： Wallace SR,Oken MM,Lunetta KL,Panoskaltsis-Mortari A,Masellis AM

更新日期：2001-04-01 00:00:00

abstract：:A case of angiosarcoma of the breast with a fatal outcome is reported, and the world literature on this rare type of breast tumor is reviewed. Familiarity with the clinical and pathologic features of this entity is essential in avoiding underdiagnosis and delay of definitive treatment. The three-year survival rate of ...

journal_title：Cancer

authors： Chen KT,Kirkegaard DD,Bocian JJ

更新日期：1980-07-15 00:00:00

abstract：:Although cancer often is referred to as "a disease of the genes," it is indisputable that the (epi)genetic properties of individual cancer cells are highly variable, even within the same tumor. Hence, preexisting resistant clones will emerge and proliferate after therapeutic selection that targets sensitive clones. He...

journal_title：Cancer

authors： Napel S,Mu W,Jardim-Perassi BV,Aerts HJWL,Gillies RJ

更新日期：2018-12-15 00:00:00

abstract：:We detected cytoplasmic estrogen receptors (ER) in only 4 of 34 (12%) patients with malignant melanoma. The titers as assayed by the dextran-coated charcoal method were 3, 3, 4, and 5 fmol/mg, respectively. Our data indicate that the incidence of melanoma with detectable ER is low, which suggests that any potential cl...

journal_title：Cancer

authors： Creagan ET,Ingle JN,Woods JE,Pritchard DJ,Jiang NS

更新日期：1980-10-15 00:00:00

abstract：:K-ras gene mutation in colorectal tumors from patients with familial polyposis coli were investigated using oligonucleotide probes specific for a mutation at codon 12, 13, or 61 of the K-ras gene. The authors examined 22 colorectal carcinomas and 51 colorectal adenomas from 41 familial polyposis coli patients and obse...

journal_title：Cancer

authors： Sasaki M,Sugio K,Sasazuki T

更新日期：1990-06-01 00:00:00