Prognostic factors in male urethral cancer.

abstract：BACKGROUND:Hypercalcemia has rarely been reported in patients with Richter's syndrome (RS). In this article, the authors report four cases with complementary pathophysiologic examinations. METHODS:Four patients with hypercalcemia that indicated RS were admitted to the study unit between 1980 and 1994 with the followin...

journal_title：Cancer

authors： Beaudreuil J,Lortholary O,Martin A,Feuillard J,Guillevin L,Lortholary P,Raphael M,Casassus P

更新日期：1997-03-15 00:00:00

abstract：BACKGROUND:Although significant advances have been made in the treatment of some malignancies, the prognosis of patients with metastatic tumors remains poor. Differentiating agents redirect cells toward their normal phenotype and therefore may reverse or suppress evolving malignant lesions or prevent cancer invasion. I...

journal_title：Cancer

authors： Miller WH Jr

更新日期：1998-10-15 00:00:00

abstract：BACKGROUND:The purpose of the current study was to determine the prevalence of low bone mineral density (BMD) (ie, osteopenia) and identify factors associated with low BMD in young adult survivors of childhood acute lymphoblastic leukemia (ALL). METHODS:Dual energy x-ray absorptiometry was used to evaluate BMD in 74 r...

journal_title：Cancer

authors： Thomas IH,Donohue JE,Ness KK,Dengel DR,Baker KS,Gurney JG

更新日期：2008-12-01 00:00:00

abstract：:Twenty-nine cases of non-Hodgkin's lymphoma of Waldeyer's ring (W-NHL) and nasal cavity or paranasal sinus (N-NHL) were studied for tumor-surface marker phenotype and histopathologic correlation with clinical features. Immunostaining procedures on tissue sections by using xenoantisera and monoclonal antibodies to huma...

journal_title：Cancer

authors： Yamanaka N,Harabuchi Y,Sambe S,Shido F,Matsuda F,Kataura A,Ishii Y,Kikuchi K

更新日期：1985-08-15 00:00:00

abstract：:We have reviewed the records of 76 patients with Stage I or II extranodal non-Hodgkin's lymphoma who were referred to the Division of Radiation Oncology, Mallinckrodt Institute of Radiology, during the years 1964 through 1974. The histologic slides were reviewed in the 67 cases in which they were available. Forty-thre...

journal_title：Cancer

authors： Mill WB,Lee FA,Franssila KO

更新日期：1980-02-15 00:00:00

abstract：:An 11-year-old female with a large embryonal carcinoma of the left ovary was treated by unilateral salpingo-oophorectomy combined with a systemic chemotherapy of a total dose of 1.9 mg of dactinomycin. The preoperative serum alpha-fetoprotein (AFP) level of 70,350 ng/ml decreased to 270 ng/ml 5 weeks after the operati...

journal_title：Cancer

authors： Nakakuma K,Tashiro S,Uemura K,Takayama K

更新日期：1983-10-15 00:00:00

abstract：BACKGROUND:Sixty percent of patients with stage IV melanoma may develop brain metastases, which result in significantly increased morbidity and a poor overall prognosis. Phase 3 studies of melanoma usually exclude patients with untreated brain metastases; therefore, clinical data for intracranial responses to treatment...

journal_title：Cancer

authors： Holbrook K,Lutzky J,Davies MA,Davis JM,Glitza IC,Amaria RN,Diab A,Patel SP,Amin A,Tawbi H

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Programmed death 1 (PD-1) signaling in the tumor microenvironment dampens immune responses to cancer, and blocking this axis induces antitumor effects in several malignancies. Clinical studies of PD-1 blockade are only now being initiated in pediatric patients, and little is known regarding programmed death-...

journal_title：Cancer

authors： Majzner RG,Simon JS,Grosso JF,Martinez D,Pawel BR,Santi M,Merchant MS,Geoerger B,Hezam I,Marty V,Vielh P,Daugaard M,Sorensen PH,Mackall CL,Maris JM

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Although there have been a few reports dealing with the sarcomatous changes of intrahepatic cholangiocarcinoma, its clinicopathologic features as well as immunohistochemical nature remain obscure. METHODS:Among 155 cases of intrahepatic cholangiocarcinoma, 7 cases of sarcomatous cholangiocarcinoma were chos...

journal_title：Cancer

authors： Nakajima T,Tajima Y,Sugano I,Nagao K,Kondo Y,Wada K

更新日期：1993-09-15 00:00:00

abstract：BACKGROUND:After the introduction of a mammography screening program, the incidence of late-stage breast cancer is expected to decrease. The objective of the current study was to evaluate variations in the total incidence of breast cancer and in the incidence of breast cancers with a pathologic tumor (pT) classificatio...

journal_title：Cancer

authors： Foca F,Mancini S,Bucchi L,Puliti D,Zappa M,Naldoni C,Falcini F,Gambino ML,Piffer S,Sanoja Gonzalez ME,Stracci F,Zorzi M,Paci E,IMPACT Working Group.

更新日期：2013-06-01 00:00:00

abstract：:A case of primary hemangiosarcoma of the spleen in a 48-year-old woman is presented. Twenty-eight months after splenectomy the patient developed a severe anemia of the microangiopathic type, thrombocytopenia, and a leukoerythroblastic peripheral blood picture. In contrast to x-ray and conventional 99mTc-methylene-diph...

journal_title：Cancer

authors： Hermann GG,Fogh J,Graem N,Hansen OP,Hippe E

更新日期：1984-04-15 00:00:00

abstract：:A series of 273 unselected patients with bronchial carcinoma, comprising a total prospective 5-year study from a Swedish county with an observed 5-year survival of 7.0%, is presented. The autopsy rate in deceased patients was 94%. All diagnoses were histologically or cytologically verified. The 5-year survival rates f...

journal_title：Cancer

authors： Nõu E

更新日期：1984-05-15 00:00:00

abstract：BACKGROUND:Glioblastoma multiforme (GBM) is the most frequent primary brain tumor in adults. Temozolomide was rapidly incorporated into first-line treatment following the publication of the pivotal European Organization for Research and Treatment of Cancer-National Cancer Institute of Canada phase 3 trial in 2005. Howe...

journal_title：Cancer

authors： Lawrence YR,Mishra MV,Werner-Wasik M,Andrews DW,Showalter TN,Glass J,Shen X,Symon Z,Dicker AP

更新日期：2012-09-01 00:00:00

abstract：:Werner's syndrome, a relatively rare and autosomal recessive disorder, is well known to be characterized by a high frequency of malignant neoplasm. The occurrence of familial neoplasm in patients with this condition, however, has been recorded only once before in the literature. Reported are the findings with regard t...

journal_title：Cancer

authors： Usui M,Ishii S,Yamawaki S,Hirayama T

更新日期：1984-12-01 00:00:00

abstract：:A 20-year-old man with previously treated lymphoblastic lymphoma, a known T-cell disorder, developed progressive disease despite intensive combination chemotherapy with doxorubicin, vincristine, and prednisone. He was subsequently treated with a 21-day course of intravenous antithymocyte globulin at a dose of approxim...

journal_title：Cancer

authors： Wong KK Jr,Sweet DL,Variakojis D

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:Mycosis fungoides (MF) is predominantly a disease of older patients, but occasionally occurs in children. The aims of the current study were to describe the clinical presentation, pathologic features, and disease progression (DP) in patients who developed MF before age 16 years. METHODS:A retrospective stud...

journal_title：Cancer

authors： Wain EM,Orchard GE,Whittaker SJ,Spittle M Sc MF,Russell-Jones R

更新日期：2003-11-15 00:00:00

abstract：:In three cases of oligodendrogliomas, atypical cells rich in eosinophilic cytoplasm, resembling plump astroyctic or astroblastic cells, were studied under the electron microscopy. These cells showed finely granular cytoplasm with routine hematoxylin-eosin preparation; ultrastructurally, they exhibited abundant, round ...

journal_title：Cancer

authors： Takei Y,Mirra SS,Miles ML

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:Splenic and nodal marginal zone lymphomas (MZL) are subtypes of marginal zone-derived neoplasms. Due to their rarity, little is known concerning their relation, pattern of dissemination, and treatment outcome. METHODS:The authors analyzed the clinicopathologic features and outcome of 43 patients (34 patient...

journal_title：Cancer

authors： Arcaini L,Paulli M,Boveri E,Vallisa D,Bernuzzi P,Orlandi E,Incardona P,Brusamolino E,Passamonti F,Burcheri S,Schena C,Pascutto C,Cavanna L,Magrini U,Lazzarino M

更新日期：2004-01-01 00:00:00

abstract：:In order to determine if recombinant interleukin-2 (rIL-2) can induce lymphokine-activated killer (LAK) cells able to lyse autologous leukemic cells, we incubated peripheral blood (PB) mononuclear cells from children with acute leukemia with 50 U/ml rIL-2 for 5 days. These PB effector cells were then tested for their ...

journal_title：Cancer

authors： Findley HW Jr,Abdel Mageed A,Nasr SA,Ragab AH

更新日期：1988-11-01 00:00:00

abstract：:We present a case with the unusual association of Graves' disease and functioning pulmonary metastases of follicular thyroid carcinoma. Unlike other reports of thyroid cancer and thyrotoxicosis, this patient's hyperthyroidism was related to a hyperfunctioning primary thyroid neoplasm and not merely to large amounts of...

journal_title：Cancer

authors： Grayzel EF,Bennett B

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:Even when they are analogous in microscopic and macroscopic appearance, tumors vary in their response rates to radiotherapy. Cell culture and xenograft experiments with colorectal cell lines have demonstrated that wild-type p53 increases radiosensitivity. Hence, the authors investigated, in a well-defined po...

journal_title：Cancer

authors： Nehls O,Klump B,Holzmann K,Lammering G,Borchard F,Gruenagel HH,Gaco V,Gregor M,Porschen R

更新日期：1999-06-15 00:00:00

abstract：:The serum lactase dehydrogenase (LDH) of 56 patients with Ewing's sarcoma was examined to determine the use of LDH as a tumor marker. The initial LDH level was used to determine its ability to predict survival. The follow-up LDH level also was examined, as an indicator of recurrent disease. The initial LDH level was f...

journal_title：Cancer

authors： Farley FA,Healey JH,Caparros-Sison B,Godbold J,Lane JM,Glasser DB

更新日期：1987-04-01 00:00:00

abstract：:Diagnostic advances currently have exceeded therapeutic gain. The present, however, is a transition phase. Chemotherapy, for example, has become curative for some tumors in recent years, rather than merely palliative, due to the precision permitted by advances in molecular biology. At this time, acceleration in the ba...

journal_title：Cancer

authors： Gusberg SB

更新日期：1987-10-15 00:00:00

abstract：BACKGROUND:Wild-type p53 protein activates the WAF1/CIP-1 (p21) gene, leading to G1 arrest after DNA damage. The authors investigated the relation of p21 and p53 expression in pancreatic adenocarcinomas to disease stage, overall patient survival, and survival when chemotherapy or radiation therapy was given. METHODS:P...

journal_title：Cancer

authors： Dergham ST,Dugan MC,Joshi US,Chen YC,Du W,Smith DW,Arlauskas P,Crissman JD,Vaitkevicius VK,Sarkar FH

更新日期：1997-08-01 00:00:00

abstract：:The quantitative analysis on glycosaminoglycan (GAG) in the tumor tissues of five patients with malignant pleural mesothelioma and in the pleural fluid of two patients was performed with the use of biochemical methods. In the tumor tissues, it was found that the average of the total amount of GAG was more than 7.9 tim...

journal_title：Cancer

authors： Nakano T,Fujii J,Tamura S,Amuro Y,Nabeshima K,Horai T,Hada T,Higashino K

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:Deletion or loss of heterozygosity (LOH) at the polymorphic loci on the short arm of chromosome 3 has been reported in a large number of renal cell, small cell lung, non-small cell lung, and cervical carcinomas, suggesting the presence of one or more putative tumor suppressor genes at chromosome 3p. Similar ...

journal_title：Cancer

authors： el-Naggar AK,Lee MS,Wang G,Luna MA,Goepfert H,Batsakis JG

更新日期：1993-08-01 00:00:00

abstract：:A 42-year-old man was admitted to the Cancer Division of the American MedicalCenter in February, 1956. He had been treated for erythrocytosis beginning 6 months previously, with reduction of his hemoglobin to relatively normal values. On admission, a huge tumor of the left kidney was palable. Roentgenograms of the ...

journal_title：Cancer

authors： Downing V,Levine S

更新日期：1975-06-01 00:00:00

abstract：BACKGROUND:There is little information on the function of dendritic cells in women with human papillomavirus (HPV)-related cervical squamous intraepithelial lesions (SILs). In the current study the functions of dendritic cells in the development of T-cell immunity in women with cervical SILs were assessed. METHODS:The...

journal_title：Cancer

authors： Lee BN,Follen M,Rodriquez G,Shen DY,Malpica A,Shearer WT,Reuben JM

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:As androgen deprivation therapy (ADT) becomes a standard of treatment for men with recurrent or metastatic prostate cancer, evaluation of adverse effects associated with this treatment is needed. In this study, the authors evaluated the effect of ADT administered as monotherapy and in combination with local ...

journal_title：Cancer

authors： Sadetsky N,Greene K,Cooperberg MR,Hubbard A,Carroll PR,Satariano W

更新日期：2011-10-01 00:00:00

abstract：:Twenty-four women with ovarian carcinoma that had metastasized to the liver were treated with intrahepatic infusional therapy. No consistent drug regimen was used. There were no complete responders; however, 33% had a partial response. All responses were noticed after the first course of therapy. The median length of ...

journal_title：Cancer

authors： Malone JM Jr,Gershenson DM,Carrasco CH,Charansangavej C,Copeland LJ,Larson DM,Kavanagh JJ,Edwards CL,Wallace S

更新日期：1987-06-01 00:00:00