Treatment trade-offs in myeloma: A survey of consecutive patients about contemporary maintenance strategies.

abstract：:This article describes two patients with hepatic metastases from colorectal cancer in whom a reversible enteropathy developed during the administration of hepatic artery infusion chemotherapy with 5-fluoro-2-deoxyuridine (5-FUdR) via an Infusaid Series 400 pump (Infusaid Corp., Sharon, MA). Both patients had severe di...

journal_title：Cancer

authors： Gluck WL,Akwari OE,Kelvin FM,Goodwin BJ

更新日期：1985-11-15 00:00:00

abstract：:Oral rhabdomyosarcoma (RMS) was studied by analysis of eight such cases which presented over a 25-year period. Rhabdomyosarcoma was the fourth most common oral sarcoma (7.5%) from this period after osteosarcoma (32%), fibrosarcoma (19%), and chondrosarcoma (9%). In patients younger than 20 years, RMS was the second mo...

journal_title：Cancer

authors： Peters E,Cohen M,Altini M,Murray J

更新日期：1989-03-01 00:00:00

abstract：:Two cases of primary linitis plastica of the large intestine will be presented and discussed. Characteristic clinical features of this type of adenocarcinoma of the large intestine include younger age of presentation, low incidence of hepatic metastasis and a high incidence of ovarian, lymph node and peritoneal metast...

journal_title：Cancer

authors： Amorn Y,Knight WA Jr

更新日期：1978-06-01 00:00:00

abstract：:The clinical, patient-oriented focus of medicine and psychology is contrasted with the epidemiologic (public health) approach in assessing the role of life-style factors and health promotion in cancer research. The unifying host-agent-environment epidemiologic paradigm is applied to contemporary cancer prevention issu...

journal_title：Cancer

authors： Celentano DD

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:During hospitalization for hematopoietic stem cell transplantation (HCT), patients experience a steep deterioration in quality of life (QOL) and mood. To our knowledge, the impact of this deterioration on patients' QOL and posttraumatic stress disorder (PTSD) symptoms after HCT is unknown. METHODS:We conduc...

journal_title：Cancer

authors： El-Jawahri AR,Vandusen HB,Traeger LN,Fishbein JN,Keenan T,Gallagher ER,Greer JA,Pirl WF,Jackson VA,Spitzer TR,Chen YB,Temel JS

更新日期：2016-03-01 00:00:00

abstract：:A young woman with a very extensive intramedullary hemangioblastoma of the spinal cord was treated with a moderately high dose of irradiation after biopsy only of the tumor. Now, five years following treatment, there have been no radiation sequelae and no evidence of progressive disease. ...

journal_title：Cancer

authors： Richardson RG,Griffin TW,Parker RG

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:The treatment of metastatic renal cell carcinoma (RCC) with high-dose interleukin-2 (HD IL-2) has resulted in durable tumor regression in a minority of patients. The current study presents the authors' 20-year experience administering this immunotherapeutic agent. METHODS:Patients with metastatic RCC (n = 2...

journal_title：Cancer

authors： Klapper JA,Downey SG,Smith FO,Yang JC,Hughes MS,Kammula US,Sherry RM,Royal RE,Steinberg SM,Rosenberg S

更新日期：2008-07-15 00:00:00

abstract：BACKGROUND:The histogenesis of carcinosarcoma is still unknown. METHODS:A new human uterine cell line, EMTOKA, derived from a carcinosarcoma of the uterus, has been passed successfully in cell culture for more than 2 years. The cell line was established on April 11, 1989, in a uterine tumor of a 64-year-old Japanese w...

journal_title：Cancer

authors： Gorai I,Doi C,Minaguchi H

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:The 5-year survival rate of patients with submucosal (sm) esophageal carcinoma continues to be much worse than that with intramucosal (m) lesions. The reasons are unclear, but matrix metalloproteinases (MMPs) and membrane type matrix metalloproteinases (MT-MMPs) are known to be involved in degradation of ext...

journal_title：Cancer

authors： Ohashi K,Nemoto T,Nakamura K,Nemori R

更新日期：2000-05-15 00:00:00

abstract：BACKGROUND:A clinicopathologic evaluation of clinical Stage I and II uterine sarcoma was done by the Gynecologic Oncology Group from 1979-1988. METHODS:After all eligibility criteria were met, 453 cases were evaluable and analyzed for prognostic factors. RESULTS:Of the 301 mixed mesodermal tumors (MMT), 167 were homo...

journal_title：Cancer

authors： Major FJ,Blessing JA,Silverberg SG,Morrow CP,Creasman WT,Currie JL,Yordan E,Brady MF

更新日期：1993-02-15 00:00:00

abstract：BACKGROUND:In less than a century, lung cancer has progressed from a medical curiosity to the most deadly of all malignant diseases on our planet. Because cigarette smoking is responsible for the existing global lung cancer epidemic, policy initiatives have focused almost exclusively on primary prevention. There is no ...

journal_title：Cancer

authors： Strauss GM,Dominioni L

更新日期：2000-12-01 00:00:00

abstract：:Major advances have been made in melanoma treatment with the use of molecularly targeted therapies and immunotherapies, and numerous regimens are now approved by the US Food and Drug Administration for patients with stage IV disease. However, therapeutic resistance remains an issue to both classes of agents, and relia...

journal_title：Cancer

authors： Szczepaniak Sloane RA,Gopalakrishnan V,Reddy SM,Zhang X,Reuben A,Wargo JA

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Helicobacter pylori recently was identified as a risk factor for gastric cancer. Its association with preneoplastic conditions of the stomach, however, is undocumented. METHODS:Gastric biopsy specimens from 245 symptomatic patients were examined for neoplastic and preneoplastic lesions and for gastric H. py...

journal_title：Cancer

authors： Guarner J,Mohar A,Parsonnet J,Halperin D

更新日期：1993-01-15 00:00:00

abstract：:Five patients with hepatocellular carcinoma in the caudate lobe were evaluated. Computed tomography (CT) scan and/or angiography clearly demonstrated multiple intrahepatic metastases in four (80%), and tumor thrombi in the portal vein in two (40%), and in the inferior vena cava in one. Even though there was no recogni...

journal_title：Cancer

authors： Takayasu K,Muramatsu Y,Shima Y,Goto H,Moriyama N,Yamada T,Makuuchi M,Kaneko A,Itabashi M,Shimamura Y

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:There is little information on the function of dendritic cells in women with human papillomavirus (HPV)-related cervical squamous intraepithelial lesions (SILs). In the current study the functions of dendritic cells in the development of T-cell immunity in women with cervical SILs were assessed. METHODS:The...

journal_title：Cancer

authors： Lee BN,Follen M,Rodriquez G,Shen DY,Malpica A,Shearer WT,Reuben JM

更新日期：2006-09-01 00:00:00

abstract：:A hybrid radiofrequency heating system previously reported to produce highly focused heating patterns at less than or equal to 10 cm depth in phantom models was utilized to selectively heat hypervascular, heat resistant rabbit V-2 tumors implanted in the left hindlimb. Spheroidal heating patterns 3 to 4 cm in diameter...

journal_title：Cancer

authors： Boddie AW Jr,Merritt DR,Yamanashi W,Frazer JW,McBride CM,Martin RG

更新日期：1985-03-15 00:00:00

abstract：BACKGROUND:Tyrosine kinases, such as c-KIT, c-ABL, and platelet-derived growth factor-beta (PDGFR-beta), are important regulators of cell growth. Highly potent and selective inhibitors of tyrosine kinases are being investigated as alternatives to standard chemotherapy. One such inhibitor, imatinib mesylate, is being us...

journal_title：Cancer

authors： Schmandt RE,Broaddus R,Lu KH,Shvartsman H,Thornton A,Malpica A,Sun C,Bodurka DC,Gershenson DM

更新日期：2003-08-15 00:00:00

abstract：:The incidence of gastric cancer has declined markedly in Finland during the last 4 decades. To document the changes caused by that in the ratio of the intestinal type (IT) to the diffuse type (DT) of gastric carcinoma we compared the 367 cases diagnosed from southwestern Finland at the Department of Pathology, Turku U...

journal_title：Cancer

authors： Laurén PA,Nevalainen TJ

更新日期：1993-05-15 00:00:00

abstract：BACKGROUND:The American Cancer Society has sponsored community-based, low-cost, Breast Cancer Detection Awareness Projects throughout the United States. The authors hypothesized that these projects tend to exclude minorities and women of lower socioeconomic status--groups with a higher incidence of late-stage disease. ...

journal_title：Cancer

authors： Roetzheim RG,Vandurme DJ,Brownlee HJ,Herold AH,Pamies RJ,Woodard L,Blair C

更新日期：1992-09-01 00:00:00

abstract：:The experience of 260 patients with endometrial carcinoma was reviewed. The influence of factors such as age, stage of disease, grade and degree of myometrial penetration on the survival was presented, showing that survival decreases in elderly patients, in patients with advanced stage of disease, when the tumor is un...

journal_title：Cancer

authors： Tavares MA,Patricio MB,Vilhena M,Da Silva JN

更新日期：1977-02-01 00:00:00

abstract：:We report the clinical and pathologic features of two cases of adenosarcoma. Our first case occurred in the ovary of a 51-year-old woman with extensive pelvic involvement. She was treated vigorously with radiation and chemotherapy and at the present time almost 9 years later the patient is free of disease. This repres...

journal_title：Cancer

authors： Valdez VA,Planas AT,Lopez VF,Goldberg M,Herrera NE

更新日期：1979-04-01 00:00:00

abstract：:Laparoscopy is highly effective in diagnosing malignant liver disease, with overall accuracy in the 90% range. Up to 80% of the liver surface can be inspected, and biopsies can be directed with precision. A major advantage over scan guided percutaneous techniques is the ability to detect and biopsy lesions only a few ...

journal_title：Cancer

authors： Lightdale CJ

更新日期：1982-12-01 00:00:00

abstract：:Hereditary cancer represents approximately 5-10% of the total cancer burden and may account for 60,000 to 120,000 new cancer occurrences this year in the United States. New developments in molecular genetics and the cloning of cancer-prone genes have intensely fueled interest in dealing with hereditary forms of cancer...

journal_title：Cancer

authors： Lynch HT,Watson P,Shaw TG,Lynch JF,Harty AE,Franklin BA,Kapler CR,Tinley ST,Liu B

更新日期：1999-12-01 00:00:00

abstract：:Patients with Philadelphia chromosome-positive chronic myelogenous leukemia (CML) were treated with a combination of alpha-interferon and gamma-interferon. Recombinant alpha-2a-interferon (Roferon-A, Hoffmann-LaRoche, Inc., Nutley, NJ) and recombinant gamma-interferon (Genentech, Inc., South San Francisco, CA) were ad...

journal_title：Cancer

authors： Talpaz M,Kurzrock R,Kantarjian H,Rothberg J,Saks S,Evans L,Gutterman JU

更新日期：1991-11-15 00:00:00

abstract：:Eleven patients with advanced soft tissue sarcoma were treated with whole body hyperthermia (41.8 degrees C-43.0 degrees C) for 2 hours, doxorubicin (45 mg/m2) at the beginning of peak temperature and cyclophosphamide (1000 mg/m2) 6 hours after doxorubicin. Warming was accomplished with a nylon and vinyl mesh water pe...

journal_title：Cancer

authors： Gerad H,van Echo DA,Whitacre M,Ashman M,Helrich M,Foy J,Ostrow S,Wiernik PH,Aisner J

更新日期：1984-06-15 00:00:00

abstract：BACKGROUND:Since endoscopic treatment was first evaluated and established as a treatment for patients with early stage gastric carcinoma, metachronous disease recurrence at other sites in the stomach after endoscopic treatment has become a major problem. METHODS:A retrospective case-control study was conducted on 10 p...

journal_title：Cancer

authors： Kawamura A,Adachi K,Ishihara S,Katsube T,Takashima T,Yuki M,Amano K,Fukuda R,Yamashita Y,Kinoshita Y

更新日期：2001-01-15 00:00:00

abstract：:A series of consecutive trials were undertaken to determine whether higher doses of intravenous metoclopramide and combinations of metoclopramide, dexamethasone, and diphenhydramine would improve antiemetic control or decrease treatment-related side effects in patients receiving cisplatin at 120 mg/m2. Metoclopramide ...

journal_title：Cancer

authors： Kris MG,Gralla RJ,Tyson LB,Clark RA,Kelsen DP,Reilly LK,Groshen S,Bosl GJ,Kalman LA

更新日期：1985-02-01 00:00:00

abstract：:Amyloid as defined by positive Congo red green birefringence and STB red birefringence was observed in the stroma of a tubular carcinoma of minor salivary gland origin. The amyloid exhibited additional histochemical characteristics of immunamyloid, viz., positive DMAB-nitrate and DC-reactions and spontaneous autofluor...

journal_title：Cancer

authors： David R,Buchner A

更新日期：1978-05-01 00:00:00

abstract：:Clinical trials are becoming increasingly difficult to carry out in the face of a changing health care delivery system. The reluctance of third party payers to reimburse for experimental therapy and the growing practice of providers to limit resources allocated for the care of cancer patients undergoing such therapies...

journal_title：Cancer

authors： Engelking C

更新日期：1991-03-15 00:00:00

abstract：:Plasma TSH and thyroxine levels were measured in 74 early breast cancer patients and 53 with advanced disease, 77 patients with cancer arising in other organs and 67 healthy women of similar age. The mean plasma TSH levels were higher in the breast cancer cases than the other two groups; the difference was statistical...

journal_title：Cancer

authors： Rose DP,Davis TE

更新日期：1978-02-01 00:00:00