Expression of c-ABL, c-KIT, and platelet-derived growth factor receptor-beta in ovarian serous carcinoma and normal ovarian surface epithelium.

abstract：:From 1977, 29 patients with inoperable non-small cell lung carcinoma due to locally far-advanced disease underwent lung resection after receiving two to eight courses of chemotherapy. After the surgery was performed, three additional courses of chemotherapy were given. The overall median survival from onset of the che...

journal_title：Cancer

authors： Takita H,Regal AM,Antkowiak JG,Rao UN,Botsoglou NK,Lane WW

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Extragonadal germ cell tumors (EGGCT) are uncommon, occur primarily in the mediastinum and retroperitoneum, and have been noted to have variable response rates to cisplatin-based chemotherapy regimens. METHODS:The Southwest Oncology Group (SWOG) has completed a prospective trial of combination chemotherapy ...

journal_title：Cancer

authors： Bukowski RM,Wolf M,Kulander BG,Montie J,Crawford ED,Blumenstein B

更新日期：1993-04-15 00:00:00

abstract：:Proviral DNA of adult T-cell leukemia virus (HTLV-I) was examined by the standard Southern blotting method in lymph nodes of 45 patients with anti-HTLV-I antibody (ATLA)-positive adult T-cell leukemia/lymphoma (ATLL). Six of these patients revealed no monoclonal proviral HTLV-I DNA in tumor cells. These six patients s...

journal_title：Cancer

authors： Yoshida T,Kikuchi M,Ooshima K,Takeshita M,Kimura N,Kozuru M,Satoh H

更新日期：1989-12-15 00:00:00

abstract：BACKGROUND:Previous investigators have detected shifts to lower stages at diagnosis for renal cell carcinoma and prostate cancer. The authors investigated whether a similar pattern is seen for urothelial carcinomas of the bladder, ureter, and renal pelvis and sought to identify changes in cancer grade and survival tren...

journal_title：Cancer

authors： David KA,Mallin K,Milowsky MI,Ritchey J,Carroll PR,Nanus DM

更新日期：2009-04-01 00:00:00

abstract：:A 58-year-old patient with metastatic prostatic carcinoma had two well-documented episodes of disseminated intravascular coagulation (DIC) occurring 1 year apart and resolving without heparin therapy. This case illustrates that DIC need not have a poor prognosis and may resolve spontaneously despite progressive cancer...

journal_title：Cancer

authors： Alving BM,Abeloff MD,Bell W

更新日期：1976-02-01 00:00:00

abstract：:Glutamine may be an essential dietary component, especially for the support of intestinal mucosal growth and function. This study evaluated the effects of a glutamine-enriched elemental diet, administered before whole-abdominal radiation on gut glutamine metabolism, mucosal morphometrics, and bacterial translocation. ...

journal_title：Cancer

authors： Klimberg VS,Souba WW,Dolson DJ,Salloum RM,Hautamaki RD,Plumley DA,Mendenhall WM,Bova FJ,Khan SR,Hackett RL

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:The role of prophylactic cranial irradiation (PCI) for patients with limited-stage small cell lung cancer (LSSCLC) remains a controversial issue. This study evaluated PCI in patients with LSSCLC who achieved a complete response to initial chemotherapy. METHODS:A retrospective case study of all nonprotocol p...

journal_title：Cancer

authors： Liengswangwong V,Bonner JA,Shaw EG,Foote RL,Frytak S,Richardson RL,Creagan ET,Eagan RT,Su JQ

更新日期：1995-03-15 00:00:00

abstract：BACKGROUND:An estimated 5-10% of all pancreatic adenocarcinomas have a hereditary association. The objective of the current study was to characterize the clinical and pathologic features of familial pancreatic carcinoma and to determine potential differences in demographics, risk factors, and outcomes between familial ...

journal_title：Cancer

authors： James TA,Sheldon DG,Rajput A,Kuvshinoff BW,Javle MM,Nava HR,Smith JL,Gibbs JF

更新日期：2004-12-15 00:00:00

abstract：:Categories of objective response to chemotherapy for 460 advanced relapsing prostate cancer patients evaluated in the initial first four randomized clinical trials of the National Prostatic Cancer Project were compared by survival and other patient and disease characteristics. The response criteria for stable were sho...

journal_title：Cancer

authors： Slack NH,Mittelman A,Brady MF,Murphy GP

更新日期：1980-12-01 00:00:00

abstract：:Mixed cellularity Hodgkin's disease and diffuse non-Hodgkin's lymphoma, mixed cell type, occurred consecutively in a husband and wife. Both patients demonstrated monoclonal IgM gammopathies. The unusual nature and possible significance of these findings are discussed. ...

journal_title：Cancer

authors： Offit K,Macris NT,Hellman G,Rotterdam HZ

更新日期：1986-01-15 00:00:00

abstract：:Compliance in oncology clinic attendance was prospectively evaluated over a 12-month period at Harlem Hospital Center, an inner city municipal facility serving a predominantly black population. One hundred patients were followed (97 blacks, 2 Hispanics, 1 white) with an average age of 60 years. There were 41 men and 5...

journal_title：Cancer

authors： Garrett TJ,Ashford A,Savage DG

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:A series of retrospective studies have reported that patients with human epidermal growth factor receptor 2(HER2)-positive breast cancer are at a greater risk of central nervous system (CNS) metastases. Trastuzumab, which does not cross the blood-brain barrier, has been associated with this increased risk. ...

journal_title：Cancer

authors： Musolino A,Ciccolallo L,Panebianco M,Fontana E,Zanoni D,Bozzetti C,Michiara M,Silini EM,Ardizzoni A

更新日期：2011-05-01 00:00:00

abstract：:Neuroendocrine small cell carcinoma is a lethal, but rare, tumor that arises most frequently in the lung. Small cell cancer also rarely may occur in the female genital tract, usually in the cervix. This article concerns the fourth reported case of neuroendocrine small cell carcinoma of the vulva. Previously, small cel...

journal_title：Cancer

authors： Cliby W,Soisson AP,Berchuck A,Clarke-Pearson DL

更新日期：1991-05-01 00:00:00

abstract：:New approaches are needed in the treatment of advanced breast cancer. In vitro studies have shown that recombinant tumor necrosis factor (TNF) is a growth inhibitor for the MCF-7, ZR-75-1, and BT-20 human breast cancer cell lines. Based on these considerations, the Southwest Oncology Group performed a Phase II trial o...

journal_title：Cancer

authors： Budd GT,Green S,Baker LH,Hersh EP,Weick JK,Osborne CK

更新日期：1991-10-15 00:00:00

abstract：:In a former series of 60 resected Stage II nonseminomatous germinal testis tumors the authors succeeded in demonstrating that adjuvant cisplatin, vinblastine, and bleomycin (PVB) was able to significantly improve survival (100% in 11 treated versus 28.5% in 7 historical controls, P less than 0.01) only in patients wit...

journal_title：Cancer

authors： Pizzocaro G,Zanoni F,Milani A,Piva L,Salvioni R,Pasi M,Pilotti S,Monfardini S

更新日期：1984-03-15 00:00:00

abstract：BACKGROUND:To describe continuing care and rehabilitation needs of cancer patients, a longitudinal design (6 months) was performed among patients 50 years of age and older with solid tumors. The study examined how age, type of treatment, site of cancer, and symptom experience affect physical functioning and their menta...

journal_title：Cancer

authors： Given CW,Given BA,Stommel M

更新日期：1994-10-01 00:00:00

abstract：:A clinical trial was conducted at the Institut Gustave Roussy between October 1972 and December 1980 to compare mastectomy with local excision plus Cobalt-irradiation, in patients with breast cancer tumors of 20 mm in diameter or less at macroscopic examination. Low-axillary dissection and extemporaneous histologic ex...

journal_title：Cancer

authors： Sarrazin D,Lê M,Rouëssé J,Contesso G,Petit JY,Lacour J,Viguier J,Hill C

更新日期：1984-03-01 00:00:00

abstract：:One hundred two long-term survivors of childhood cancers with second malignant neoplasms (SMNs) were collected from 10 institutions. Forty-seven cases fulfilling study criteria were studied to determine the risk of developing a SMN in irradiated fields after exposure to various chemotherapeutic agents. The case contro...

journal_title：Cancer

authors： D'Angio GJ,Meadows A,Miké V,Harris C,Evans A,Jaffe N,Newton W,Schweisguth O,Sutow W,Morris-Jones P

更新日期：1976-02-01 00:00:00

abstract：BACKGROUND:The aims of this study were to compare human epidermal growth factor receptor 2 (HER2) results between immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH), and to investigate the clinicopathological characteristics and outcomes according to their results. METHODS:Using consecutive tissu...

journal_title：Cancer

authors： Park S,Park HS,Koo JS,Yang WI,Kim SI,Park BW

更新日期：2012-02-15 00:00:00

abstract：BACKGROUND:The combination of a platinating agent and etoposide has induced responses in various pediatric tumors. The study estimated the maximum tolerated dose (MTD) of an oxaliplatin and etoposide regimen in children with recurrent solid tumors. METHODS:Oxaliplatin was administered on Day 1 and etoposide on Days 1 ...

journal_title：Cancer

authors： McGregor LM,Spunt SL,Santana VM,Stewart CF,Ward DA,Watkins A,Laningham FH,Ivy P,Furman WL,Fouladi M

更新日期：2009-02-01 00:00:00

abstract：:The authors recently reported the antigenic phenotypes of three cases of so-called "malignant angioendotheliomatosis" and suggested that angiotropic large cell lymphoma (ALCL) is a more appropriate designation for this disease. The authors now report an additional seven cases of ALCL with unique clinical presentations...

journal_title：Cancer

authors： Stroup RM,Sheibani K,Moncada A,Purdy LJ,Battifora H

更新日期：1990-10-15 00:00:00

abstract：BACKGROUND:Pediatric rhabdomyosarcomas (RMS) have a more advantageous prognosis after multimodality treatment compared with adult RMS, which might be related to a decreased sensitivity to chemotherapy in adults. Resistance to chemotherapy might be conveyed by the multidrug resistance (MDR)-associated proteins P-glycopr...

journal_title：Cancer

authors： Komdeur R,Klunder J,van der Graaf WT,van den Berg E,de Bont ES,Hoekstra HJ,Molenaar WM

更新日期：2003-04-15 00:00:00

abstract：:Two cases of primary linitis plastica of the large intestine will be presented and discussed. Characteristic clinical features of this type of adenocarcinoma of the large intestine include younger age of presentation, low incidence of hepatic metastasis and a high incidence of ovarian, lymph node and peritoneal metast...

journal_title：Cancer

authors： Amorn Y,Knight WA Jr

更新日期：1978-06-01 00:00:00

abstract：:Mesenchymal chondrosarcoma, an uncommon lesion of bone and extraskeletal tissue, is rare in the orbit. A case of extraskeletal mesenchymal chondrosarcoma of the orbit in a 28-year-old woman presenting with proptosis and diminution of vision in the left eye is reported. Histologically, the tumor showed areas of undiffe...

journal_title：Cancer

authors： Bagchi M,Husain N,Goel MM,Agrawal PK,Bhatt S

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) play a crucial role in carcinogenesis; however, it largely remains unclear whether miRNAs in gastric juice, which is specific for gastric tissues, can be used as biomarkers for gastric cancer. The objective of the current study was to investigate the feasibility of using gastric juice miRN...

journal_title：Cancer

authors： Cui L,Zhang X,Ye G,Zheng T,Song H,Deng H,Xiao B,Xia T,Yu X,Le Y,Guo J

更新日期：2013-05-01 00:00:00

abstract：:The study is a clinicopathologic report on 64 patients with primary adenocarcinoma of the urinary bladder and urachus, with particular reference to important prognostic and therapeutic factors. All tumors exhibited adenocarcinomatous features in at least two thirds of the examined tumor area. Pure forms of the differe...

journal_title：Cancer

authors： Anderström C,Johansson SL,von Schultz L

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND:There is limited published evidence regarding the efficacy of total skin electron beam radiation for patients with the diffuse erythrodermic form of mycosis fungoides. METHODS:Forty-five patients with erythrodermic mycosis fungoides were managed at McMaster University in Hamilton, Ontario, Canada (n=34), an...

journal_title：Cancer

authors： Jones GW,Rosenthal D,Wilson LD

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:To the authors' knowledge there are few data that correlate the expression of the epidermal growth factor receptor (EGFR) with the outcome of patients who have breast carcinoma and are treated with anthracycline chemotherapy. METHODS:Pretreatment tumor tissue samples were available from 82 patients who had ...

journal_title：Cancer

authors： Buchholz TA,Tu X,Ang KK,Esteva FJ,Kuerer HM,Pusztai L,Cristofanilli M,Singletary SE,Hortobagyi GN,Sahin AA

更新日期：2005-08-15 00:00:00

abstract：BACKGROUND:Although it is believed that p53 suppressor gene mutations, compared with mutations in the K-ras oncogene, occur at a later stage of colorectal tumorigenesis, the distribution of these genetic alterations at an early stage remains poorly characterized. METHODS:The authors analyzed the immunoreactivity for p...

journal_title：Cancer

authors： Hosaka S,Aoki Y,Akamatsu T,Nakamura N,Hosaka N,Kiyosawa K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:The clinical value of DNA flow cytometry of colorectal cancer is unclear. The purpose of this retrospective study was to evaluate the relationship between tumor flow cytometry, histopathologic parameters, and survival. METHODS:Flow cytometry was performed on paraffin embedded specimens from 653 patients who...

journal_title：Cancer

authors： Tang R,Ho YS,You YT,Hsu KC,Chen JS,Changchien CR,Wang JY

更新日期：1995-11-15 00:00:00