Prophylactic cranial irradiation in limited-stage small cell lung cancer.

abstract：:The purpose of this study was to determine (1) the number and activity of natural killer (NK) cells in children with acute leukemia at different stages of their disease; and (2) the effect of interleukin-2 (IL-2) in enhancing NK activity of these patients' cells. The mean percentage of Leu 11+ NK cells in patients at ...

journal_title：Cancer

authors： Mageed AA,Findley HW Jr,Franco C,Singhapakdi S,Alvarado C,Chan WC,Ragab AH

更新日期：1987-12-15 00:00:00

abstract：BACKGROUND:Oral tongue cancer incidence has increased among whites in the United States; however, the cause remains unknown. If an infectious agent is implicated, then elevated risk would be expected among immunosuppressed individuals. METHODS:By using population-based registry linkage information from the US Transpla...

journal_title：Cancer

authors： Tota JE,Engels EA,Madeleine MM,Clarke CA,Lynch CF,Ortiz AP,Hernandez BY,Chaturvedi AK

更新日期：2018-06-15 00:00:00

abstract：:Elective irradiation of sites of potential occult tumor spread is often part of a patient's radiation therapy program. The required radiation dose (D) depends on the probability that occult disease exists (P(occ)), the number of sites at risk (A), the number of tumor clonogens present (Ni), their radiation sensitivity...

journal_title：Cancer

authors： Marks LB

更新日期：1990-12-15 00:00:00

abstract：:In the past all clear cell carcinomas of the female genital tract were thought to arise from mesonephric remnants. Recently increasing evidence has related their origin to müllerian rather than mesonephric epithelium. One of the main reasons that has been advanced to support their mesonephric origin has been their occ...

journal_title：Cancer

authors： Hasumi K,Ehrmann RL

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:Ovarian cancer patients frequently receive chemotherapy near the end of life. The purpose of the current study was to develop indicators that characterize those ovarian cancer patients who have a short life span. METHODS:The medical charts of deceased epithelial ovarian cancer patients were retrospectively ...

journal_title：Cancer

authors： von Gruenigen V,Daly B,Gibbons H,Hutchins J,Green A

更新日期：2008-05-15 00:00:00

abstract：BACKGROUND:Many histologic classifications of thymic epithelial tumors have been reported to date, but to the authors' knowledge, none of them closely reflect the clinical behavior or prognosis of the tumor. Therefore, it is necessary to establish a biologic marker for thymic epithelial tumors. Variants of CD44 may be ...

journal_title：Cancer

authors： Sonobe S,Miyamoto H,Nobukawa B,Izumi H,Futagawa T,Ishikawa N,Yamazaki A,Uekusa T,Abe H,Suda K

更新日期：2005-05-15 00:00:00

abstract：BACKGROUND:As a result of a major social and demographic transition, Colombia is currently undergoing major changes in disease-specific mortality rates, including an increasing burden of cancer death. The current article described some aspects of the evolution of cancer mortality in Colombia and, in particular, highlig...

journal_title：Cancer

authors： Piñeros M,Hernández G,Bray F

更新日期：2004-11-15 00:00:00

abstract：BACKGROUND:Previous studies have shown that matrix metalloproteinase-2 (MMP-2) (a 72-kilodalton Type IV collagenase/gelatinase A) is associated with breast carcinoma, but to the authors' knowledge there are no reports showing that it is prognostic for overall survival. METHODS:Expression of the immunoreactive protein ...

journal_title：Cancer

authors： Talvensaari-Mattila A,Pääkkö P,Höyhtyä M,Blanco-Sequeiros G,Turpeenniemi-Hujanen T

更新日期：1998-09-15 00:00:00

abstract：BACKGROUND:Transitional cell carcinoma (TCC) of the bladder displays an unpredictable biologic behavior and the morphologic methods of grading tumor malignancy are often insufficient to predict the clinical outcome of patients with TCC of the bladder. Thus, the new indicator should reliably reflect prognosis. In this s...

journal_title：Cancer

authors： Shiina H,Igawa M,Nagami H,Yagi H,Urakami S,Yoneda T,Shirakawa H,Ishibe T,Kawanishi M

更新日期：1996-10-15 00:00:00

abstract：:The prognostic value of nuclear DNA content was studied retrospectively using flow cytometry in 203 cases of resected hepatocellular carcinoma. The occurrence of DNA aneuploidy, which was detected in 50% of patients, correlated significantly with tumor size and the presence of vascular invasion or intrahepatic metasta...

journal_title：Cancer

authors： Fujimoto J,Okamoto E,Yamanaka N,Toyosaka A,Mitsunobu M

更新日期：1991-02-15 00:00:00

abstract：:The literature examining obesity as a barrier to screening for breast, cervical, and colorectal cancer has not been evaluated systematically. With the increasing prevalence of obesity and its impact on cancer incidence and mortality, it is important to determine whether obesity is a barrier to screening so that cancer...

journal_title：Cancer

authors： Cohen SS,Palmieri RT,Nyante SJ,Koralek DO,Kim S,Bradshaw P,Olshan AF

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:: The purpose of this study was to evaluate the impact of postmastectomy breast reconstruction on the timing of chemotherapy. METHODS:: The authors included stage I-III breast cancer patients from 8 National Comprehensive Cancer Network institutions for whom guidelines recommended chemotherapy. Surgery type...

journal_title：Cancer

authors： Alderman AK,Collins ED,Schott A,Hughes ME,Ottesen RA,Theriault RL,Wong YN,Weeks JC,Niland JC,Edge SB

更新日期：2010-04-01 00:00:00

abstract：:A total of 1026 patients with gastric cancer was followed up for five years after surgery and classified into different groups according to surgeons' assessment of nodal involvement, serosal invasion, peritoneal spread, and hepatic metastasis. The survival of each group was studied by parametric analysis, using the lo...

journal_title：Cancer

authors： Maetani S,Tobe T,Hirakawa A,Kashiwara S,Kuramoto S

更新日期：1980-12-15 00:00:00

abstract：BACKGROUND:NR4A2, an orphan nuclear receptor essential in the generation of dopaminergic neurons, has been recently linked to inflammation and cancer. This study sought to identify the role of NR4A2 on chemoresistance and postoperative prognosis of gastric cancer (GC). METHODS:NR4A2 was transfected into GC cells to in...

journal_title：Cancer

authors： Han Y,Cai H,Ma L,Ding Y,Tan X,Chang W,Guan W,Liu Y,Shen Q,Yu Y,Zhang H,Cao G

更新日期：2013-10-01 00:00:00

abstract：:In a clinical trial, 42 patients with abdominal Burkitt's lymphoma (BL) were treated with a combination regimen, code-named CVA, consisting of cyclophosphamide (CTX), vincristine, and cystosine arabinoside. In addition, intrathecal methotrexate (i.t. MTX) was administered as prophylaxis against subsequent central nerv...

journal_title：Cancer

authors： Nkrumah FK,Perkins IV,Biggar RJ

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:Sunitinib malate is an orally bioavailable tyrosine kinase inhibitor that is active against many tyrosine kinase receptors involving crucial pathways in both healthy tissues and malignant tissues. Because its use in clinical practice is quite recent, many of its possible side effects remain unknown. In this ...

journal_title：Cancer

authors： Baldazzi V,Tassi R,Lapini A,Lunghi A,Garofoli E,Caruso S,Carini M,Mazzanti R

更新日期：2012-06-15 00:00:00

abstract：BACKGROUND:Postprostatectomy adjuvant or salvage radiotherapy, when using standard fractionation, requires 6.5 to 8 weeks of treatment. The authors report on the safety and efficacy of an expedited radiotherapy course for salvage prostate radiotherapy. METHODS:A total of 108 consecutive patients were treated with salv...

journal_title：Cancer

authors： Kruser TJ,Jarrard DF,Graf AK,Hedican SP,Paolone DR,Wegenke JD,Liu G,Geye HM,Ritter MA

更新日期：2011-06-15 00:00:00

abstract：:To evaluate the utility of nuclear morphometry as a prognostic indicator in lung cancer, 5-year follow-up information was obtained in 46 cases of surgically resected Stage I non-small cell lung cancer (NSCLC). Nuclear area, perimeter, major diameter, minor diameter, and nuclear shape factor were determined from repres...

journal_title：Cancer

authors： Cagle PT,Langston C,Fraire AE,Roggli VL,Greenberg SD

更新日期：1992-05-15 00:00:00

abstract：BACKGROUND:Colonoscopic screening has increased detection of malignant colonic polyps (MPs). The goal of this study was to analyze trends and patterns in the surgical treatment of MPs and to assess outcomes as measured by lymph node retrieval and patient survival. METHODS:The Surveillance, Epidemiology, and End Result...

journal_title：Cancer

authors： Wasif N,Etzioni D,Maggard MA,Tomlinson JS,Ko CY

更新日期：2011-03-01 00:00:00

abstract：:Cases of childhood cancer (less than 15 years of age at diagnosis), diagnosed between 1960 and 1984, were obtained from the Hawaii Tumor Registry, a population-based Surveillance, Epidemiology, and End Results (SEER) participant covering the entire State of Hawaii. During the 25 years of data collection, cancer was di...

journal_title：Cancer

authors： Goodman MT,Yoshizawa CN,Kolonel LN

更新日期：1989-10-15 00:00:00

abstract：BACKGROUND:Caveolin-1 plays a regulatory role in several signaling pathways. Recently caveolin-1 was identified as a metastasis-related gene in prostate carcinoma. However, the clinical impact of caveolin-1 expression in esophageal carcinoma remains unknown. METHODS:One hundred thirty surgical specimens of esophageal ...

journal_title：Cancer

authors： Kato K,Hida Y,Miyamoto M,Hashida H,Shinohara T,Itoh T,Okushiba S,Kondo S,Katoh H

更新日期：2002-02-15 00:00:00

abstract：BACKGROUND:In multidisciplinary assessment clinics for screen-detected breast lesions, onsite cytopathologists provide immediate results of fine-needle aspiration biopsies (FNABs) and this information is used for patient counseling and treatment planning. Such consultation is not possible for the increasing proportion ...

journal_title：Cancer

authors： Farshid G,Pieterse S

更新日期：2006-06-25 00:00:00

abstract：:Data on patients with gallbladder cancer listed in the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute were reviewed. Between 1977 and 1986, 3038 patients were recorded in the Program. Histologic grade, histologic type, stage of disease, and vascular invasion were correlated...

journal_title：Cancer

authors： Henson DE,Albores-Saavedra J,Corle D

更新日期：1992-09-15 00:00:00

abstract：BACKGROUND:Smoldering multiple myeloma (SMM) presents a high risk of progression to symptomatic MM (sy-MM). Herein, we analyzed some predictors of development of sy-MM. In 144 patients with SMM, we also compared the risk of progression predicted by bone marrow plasma cell (BMPC) involvement on the bone marrow biopsy (B...

journal_title：Cancer

authors： Rago A,Grammatico S,Za T,Levi A,Mecarocci S,Siniscalchi A,De Rosa L,Felici S,Bongarzoni V,Piccioni AL,La Verde G,Pisani F,Franceschini L,Paviglianiti AL,Caravita T,Petrucci MT,De Stefano V,Cimino G,Multiple Myeloma GI

更新日期：2012-11-15 00:00:00

abstract：BACKGROUND:The aim of this retrospective study was to determine those prognostic factors associated with response to a second-line chemotherapy in patients with metastatic breast carcinoma (MBC) that was previously responsive to a first-line chemotherapy. METHODS:The 70 MBC patients studied had previously responded to...

journal_title：Cancer

authors： Brun B,Benchalal M,Lebas C,Piedbois P,Lin M,Lebourgeois JP

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Desmoplastic melanoma is an uncommon variant of cutaneous melanoma that mimics soft tissue sarcoma both clinically and morphologically. An activating point mutation of the BRAF oncogene has been identified in a high proportion of conventional cutaneous melanomas, but its frequency in the desmoplastic subtype...

journal_title：Cancer

authors： Davison JM,Rosenbaum E,Barrett TL,Goldenberg D,Hoque MO,Sidransky D,Westra WH

更新日期：2005-02-15 00:00:00

abstract：:Ependymomas originating in the sacrum or extraspinal parasacral soft tissues are rare tumors. The majority are of the myxopapillary type and may be locally destructive. Even though metastases are not uncommon in retrosacral ependymomas, they have been rarely described in intrasacral locations. A case is reported of a ...

journal_title：Cancer

authors： Miralbell R,Louis DN,O'Keeffe D,Rosenberg AE,Suit HD

更新日期：1990-05-15 00:00:00

abstract：BACKGROUND:Patients with metachronous multiple colorectal carcinomas have been reported to have a higher frequency of a family history of colorectal carcinoma, associated colorectal adenomas, and extracolonic malignancies. These clinicopathologic factors also are considered to be related to the development of metachron...

journal_title：Cancer

authors： Masubuchi S,Konishi F,Togashi K,Okamoto T,Senba S,Shitoh K,Kashiwagi H,Kanazawa K,Tsukamoto T

更新日期：1999-05-01 00:00:00

abstract：:Major findings are presented from a workshop on Quality of Life Assessment in Cancer Symptom Management Trials, sponsored by the National Cancer Institute. Data-driven research reports focused on 3 topics, 1) the rationale and utility of health-related quality of life (HRQOL) assessment, 2) conceptual models, and 3) m...

journal_title：Cancer

authors： Buchanan DR,O'Mara AM,Kelaghan JW,Sgambati M,McCaskill-Stevens W,Minasian L

更新日期：2007-10-01 00:00:00

abstract：:The case history of a woman with a "female adnexal tumor of probable Wolffian origin" is described in which the neoplasm recurred three times during a 16-year interval and responded with prolonged remission after repeated surgical excision and radiotherapy. Ultrastructural data are given to support the Wolffian nature...

journal_title：Cancer

authors： Brescia RJ,Cardoso de Almeida PC,Fuller AF Jr,Dickersin GR,Robboy SJ

更新日期：1985-09-15 00:00:00