Abstract:
:Serum immunoglobulin levels IgA, IgG, and IgM have been estimated in 92 patients with breast cancer and 50 control patients, 40 of whom had benign disease of the breast. In patients with breast cancer, IgA was significantly raised at all stages and IgG was significantly reduced, but the two abnormalities were not necessarily concomitant. These findings may suggest a disturbance in the secretory immune system, and immunologic defect even when the cancer is localized to the breast.
journal_name
Cancerjournal_title
Cancerauthors
Roberts MM,Bathgate EM,Stevenson Adoi
10.1002/1097-0142(197507)36:1<221::aid-cncr2820360subject
Has Abstractpub_date
1975-07-01 00:00:00pages
221-4issue
1eissn
0008-543Xissn
1097-0142journal_volume
36pub_type
杂志文章相关文献
CANCER文献大全abstract::The records of 1,497 patients with histologically proven adenocarcinoma of the stomach were reviewed from Charity Hospital over the 25-year period, 1948 to 1973. The operability rate was 82% and the resectability rate was 48%. In this series gastric carcinoma predominated in males and Negroes. Necropsy studies indicat...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197803)41:3<941::aid-cncr2820410
更新日期:1978-03-01 00:00:00
abstract::Distant nontraumatic clostridial myonecrosis in association with malignancy is an uncommon disorder, with only 14 well-documented cases previously reported in the English literature. Clostridium perfringens and C. septicum are the most common organisms, usually gaining access to the circulation through an ulcerated le...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860215)57:4<885::aid-cncr28205
更新日期:1986-02-15 00:00:00
abstract::Fiberoptic endoscopic examination and biopsy of the nasopharynx was done in 130 patients as a prospective study. They all had elevated titers of antibodies against the viral capsid antigen of Epstein-Barr virus but no symptoms or signs of nasopharyngeal carcinoma. Each underwent a biopsy from six fixed sites in the na...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910615)67:12<3127::aid-cncr282
更新日期:1991-06-15 00:00:00
abstract:BACKGROUND:Low-grade gliomas (LGGs) and low-grade glioneuronal tumors (LGGNTs) diagnosed during the first year of life carry unique clinical characteristics and challenges in management. However, data on the treatment burden, outcomes, and morbidities are lacking. METHODS:A retrospective study of LGGs and LGGNTs diagn...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31918
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Between 1980-1990, 126 patients were treated with radiation therapy (RT) and hyperthermia using 915-MHz external microwave applicators. All but 11 patients had failed to respond to previous therapy. METHODS:The mean tumor volume was 73 +/- 13 cm3, and the mean radiation dose delivered was 45 +/- 1 Gy. Hyper...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930701)72:1<287::aid-cncr28207
更新日期:1993-07-01 00:00:00
abstract:BACKGROUND:In 1991, the Italian Association for Pediatric Hematology-Oncology and the National Council of Research (CNR) initiated an Italian Cooperative Study (SE 91-CNR Protocol) with the main objective of improving the overall survival (SUR) and the event free survival (EFS) of children and young adults with localiz...
journal_title:Cancer
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1002/(sici)1097-0142(19990801)86:3<421::aid-cnc
更新日期:1999-08-01 00:00:00
abstract:BACKGROUND:Hepatic artery administration of iodine-131-Lipiodol serves as a modality that delivers targeted radiation therapy to hepatocellular carcinoma. Its efficacy has been promising according to trials conducted in the adjuvant setting after hepatic resection. Further investigation of its role in the palliative se...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25283
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Recent advances in the early detection of prostatic adenocarcinoma have stimulated interest in the development of techniques for determining metastatic potential. METHODS:One hundred cases of adenocarcinoma, including 66 biopsy and radical prostatectomy specimens; 20 biopsies alone; and 14 transurethral res...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19931115)72:10<3020::aid-cncr282
更新日期:1993-11-15 00:00:00
abstract:BACKGROUND:Well differentiated (WD) and dedifferentiated (DD) retroperitoneal liposarcoma (RPLS) have distinct biologic behaviors. Consequently, the therapeutic approaches for these tumors differ and mandate an accurate preoperative diagnosis. The authors of this report evaluated whether computed tomography (CT) can be...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/cncr.24045
更新日期:2009-03-01 00:00:00
abstract:BACKGROUND:A residual mediastinal mass after treatment represents a common diagnostic problem in the management of patients with Hodgkin lymphoma (HD). Conventional diagnostic radiology, computed tomography (CT), or ultrasonography (US) do not adequately reflect changes as fibrosis or necrosis. Gallium-67 (67Ga) imagin...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19930715)72:2<577::aid-cncr28207
更新日期:1993-07-15 00:00:00
abstract:BACKGROUND:There is significant need for quality follow-up care to optimize long-term outcomes for the growing population of lower gastrointestinal (GI) cancer survivors. Patient-reported outcomes (PROs) provide valuable information regarding late and long-term effects (LLTEs). METHODS:A convenience sample from 1129 c...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30527
更新日期:2017-05-15 00:00:00
abstract:BACKGROUND:Several pathologic staging systems for malignant pleural mesothelioma (MPM) have been published, but none of them provide optimal survival stratification or stage distribution among patients treated with surgery. Interpretation of prior studies that correlate pathologic factors with outcome has been confound...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24886
更新日期:2010-03-15 00:00:00
abstract::In a county hospital, 217 patients were operated on for suspected cancer of the pancreas (186 patients) and periampullary structures (31 patients). The surgeons' philosophy was to avoid biopsy of the pancreas whenever possible, they often performed radical resection based on clinical judgment alone (8% of the resectio...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820301)49:5<1035::aid-cncr2820
更新日期:1982-03-01 00:00:00
abstract:BACKGROUND:Estramustine phosphate (EMP) and flutamide (FL) were used as reversible preoperative hormonal drugs in the surgical treatment of patients with localized prostate cancer. METHODS:The authors descriptive and quantitatively examined the morphologic and immunohistochemical changes in 40 of 200 step-sectioned ra...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19941215)74:12<3164::aid-cncr282
更新日期:1994-12-15 00:00:00
abstract:BACKGROUND:Because of the structural and biochemical similarities between the antitumor p53 and p73 proteins, the authors hypothesized that individuals who carry high-risk genotypes of p53 codon 72 and p73 G4C14-to-A4T14 polymorphisms have a higher risk of developing second primary malignancy (SPM) after index squamous...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.26222
更新日期:2012-01-15 00:00:00
abstract::The lymphocytotoxic effect of therapeutic irradiation may lead to immune depression. The significance of such effects is yet to be determined in many malignancies, especially in light of the persistant immune depression in many "cured" patients. The present review examines the effects of age, type of cancer, and stage...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197702)39:2+<737::aid-cncr282039
更新日期:1977-02-01 00:00:00
abstract::The disposition of many drugs in obesity is altered, although little is known of the effect of obesity on the pharmacokinetics of anti-cancer drugs. In this report the authors describe the pharmacokinetics of high-dose methotrexate in an obese woman (184% ideal body weight) with osteosarcoma. For this patient, both th...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910915)68:6<1247::aid-cncr2820
更新日期:1991-09-15 00:00:00
abstract:BACKGROUND:Partial splenic embolization (PSE) has been used to improve hematologic parameters related to hypersplenism. The purpose of this study was to review our institutional experience with PSE for cancer patients with thrombocytopenia because of splenic sequestration precluding the administration of systemic thera...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23432
更新日期:2008-05-15 00:00:00
abstract::The cellular DNA content was determined in a consecutive series of 26 classical and two paraosteal osteosarcomas by means of single cell cytophotometry. All classical osteosarcomas regardless of histologic type (osteo-, chondro-, fibroblastic) or grade were found to be hyperploid (abnormally increased DNA content) whi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19821201)50:11<2476::aid-cncr282
更新日期:1982-12-01 00:00:00
abstract:BACKGROUND:Pathologically, benign prostatic hyperplasia (BPH) is not considered a precursor for prostate carcinoma. However, because the two conditions share not only a similar hormonal environment within the prostate but also several common risk factors, it is possible that men with BPH may be at increased risk of pro...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11710
更新日期:2003-10-15 00:00:00
abstract::High-dose multiagent chemotherapy followed by autologous marrow rescue was used in the treatment of 13 patients with Stage III or IV childhood tumors. Encouraging results are being obtained in abdominal lymphoma (1/3 complete remissions (CR); rhabdomyosarcoma (2/4 CR); and retinoblastoma (1/2 CR). In neuroblastoma, th...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19820201)49:3<603::aid-cncr28204
更新日期:1982-02-01 00:00:00
abstract:BACKGROUND:Infection is a significant cause of death in patients with aplastic anemia (AA). However, few recent studies have examined infectious complications in patients with AA. METHODS:The authors retrospectively evaluated the type of infections, associated pathogens, and outcome of infectious episodes (IEs) in pat...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11478
更新日期:2003-07-01 00:00:00
abstract:BACKGROUND:Pediatric rhabdomyosarcomas (RMS) have a more advantageous prognosis after multimodality treatment compared with adult RMS, which might be related to a decreased sensitivity to chemotherapy in adults. Resistance to chemotherapy might be conveyed by the multidrug resistance (MDR)-associated proteins P-glycopr...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.11259
更新日期:2003-04-15 00:00:00
abstract::Almost all patients with prostatic cancer will eventually escape the control of the first-line endocrine therapy and relapse. This escape is attributed to selecting and/or cloning preexisting or de novo appearing hormone-independent or resistant cell lines and occurs in most patients after a median time of 12 to 18 mo...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19920701)70:1+<329::aid-cncr2820
更新日期:1992-07-01 00:00:00
abstract::Extremely high concentrations of human chorionic gonadotropin in the cerebrospinal fluid were found in a 5-year-old boy presenting sexual precocity and leg pain. An intramedullary spinal cord tumor was revealed by myelogram and metrizamide computerized tomography, and a biopsy specimen taken at laminectomy. Histologic...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850615)55:12<2845::aid-cncr282
更新日期:1985-06-15 00:00:00
abstract::Plasma carcinoembryonic antigen (CEA) levels were studied in all available members of 17 families in which a presumed sporadic retinoblastoma had occurred. In 9 of the 17 families, close relatives of the patient had elevated CEA levels in the absence of demonstrable disease; this we have termed the "CEA family syndrom...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197603)37:3<1397::aid-cncr282037
更新日期:1976-03-01 00:00:00
abstract::The anniversary of the first publication of Cancer provides an opportunity to review the progress in liver cancer surgery in the past 60 years. Indeed, the past half century has been witness to remarkable advances in liver surgery that have provided benefit to so many patients afflicted with primary or secondary liver...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.23652
更新日期:2008-10-01 00:00:00
abstract::The effects of cigarette smoking and other factors on the accuracy of clinical diagnosis of bronchogenic carcinoma were studied retrospectively in 14,074 autopsies performed over 26 years (1948-1973) at University Hospitals of Cleveland. Within a selected study group of 415 cases diagnosed as bronchogenic carcinoma ei...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19800701)46:1<190::aid-cncr28204
更新日期:1980-07-01 00:00:00
abstract:BACKGROUND:The role of adjuvant therapy in the management of patients with malignant mixed Müllerian tumors (MMMT) of the uterus has not been defined. The outcome of planned multimodality therapy for patients with apparent early stage disease was assessed. METHODS:A pilot study was performed on 38 patients with clinic...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:
更新日期:2001-04-15 00:00:00
abstract::Studies of calcium metabolism in 38 patients with cancer indicated that: 1) intestinal absorption of calcium was reduced in patients with skeletal metastases and in those with hypercalcemia; 2) calcium-47 space (a measurement of bone turnover rate) was high in the patients with skeletal metastases; 3) hypercalcemic pa...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197611)38:5<2111::aid-cncr282038
更新日期:1976-11-01 00:00:00