Relationship of inherent resistance to doxorubicin, proliferative activity and expression of P-glycoprotein 170, and glutathione S-transferase-pi in human lung tumors.

abstract：:Spindle cell lipoma is a specific type of lipoma that is easily mistaken for a liposarcoma. An analysis of 114 cases of this tumor from the files of the Armed Forces Institute of Pathology reveals that is occurs chiefly in male patients between 45 and 70 years of age and affects the regions of the shoulder and posteri...

journal_title：Cancer

authors： Enzinger FM,Harvey DA

更新日期：1975-11-01 00:00:00

abstract：:There is a growing body of basic science and epidemiologic evidence to support a research thrust to determine whether several natural or synthetic agents, given alone or together, can lower cancer incidence. Candidate agents include analogs of vitamin A and the vitamin A precursor, beta-carotene, vitamins C and E, and...

journal_title：Cancer

authors： Malone WF,Kelloff GJ,Pierson H,Greenwald P

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Standard therapy for advanced head and neck carcinoma is surgery and radiation, and the subsequent 5-year survival with this treatment has been less than 50%. New combined modality treatment strategies are being tested to improve survival. New chemotherapy combinations are being developed and administered si...

journal_title：Cancer

authors： Dunphy FR,Boyd JH,Kim HJ,Dunphy CH,Harrison BR,Dunleavy TL,Rodriguez JJ,McDonough EM,Minster JR,Hilton JG

更新日期：1997-05-15 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor-C (VEGF-C) plays an important role in lymphangiogenesis and activates VEGF receptor-3 (VEGFR-3). Lymphatic spread is an important prognostic factor in patients with lung adenocarcinoma. The aim of the current study was to determine whether the expression of VEGF-C and VEGFR...

journal_title：Cancer

authors： Kojima H,Shijubo N,Yamada G,Ichimiya S,Abe S,Satoh M,Sato N

更新日期：2005-10-15 00:00:00

abstract：:The authors describe two cases of epithelioid sarcoma of the vulva and summarize the clinical and pathologic experience with this vulvar neoplasm. Findings indicate that epithelioid sarcoma of the vulva usually occurs in the labia majora of young women, but may occur in later life. Clinically it may mimic a Bartholin'...

journal_title：Cancer

authors： Ulbright TM,Brokaw SA,Stehman FB,Roth LM

更新日期：1983-10-15 00:00:00

abstract：:In 79 cases of histologically verified anaplastic giant-cell carcinoma, symptoms, treatment, and prognosis were documented. Seventy-eight patients are dead, the mean survival time being 2.5 months. One patient is cured. It was concluded that surgery and/or radiotherapy alone are not sufficient. The results from an add...

journal_title：Cancer

authors： Jereb B,Stjernswärd J,Löwhagen T

更新日期：1975-05-01 00:00:00

abstract：BACKGROUND:Despite known benefits to needle biopsy for suspicious breast lesions, variability in the use of this technique has been documented in practice. We sought to study the use of needle biopsy and open surgical biopsy in women with breast cancer, predictors of needle biopsy use, and the effect of biopsy choice o...

journal_title：Cancer

authors： Friese CR,Neville BA,Edge SB,Hassett MJ,Earle CC

更新日期：2009-02-15 00:00:00

abstract：:The c-Met/hepatocyte growth factor receptor and its family members are known to promote cancer cell migration and invasion. Signaling within and beyond this pathway contributes to the systemic spread of metastases through induction of the epithelial-mesenchymal transition, a process also implicated in mediating resist...

journal_title：Cancer

authors： Bhardwaj V,Cascone T,Cortez MA,Amini A,Evans J,Komaki RU,Heymach JV,Welsh JW

更新日期：2013-05-15 00:00:00

abstract：BACKGROUND:Fine-needle aspiration biopsy (FNAB) is a reliable, rapid, minimally invasive alternative to surgical biopsy when it is performed by physician specialists for the diagnosis of palpable masses. FNAB may be under-utilized in community hospitals in the U.S. because physicians without specialty training commonly...

journal_title：Cancer

authors： Florentine BD,Staymates B,Rabadi M,Barstis J,Black A,Cancer Committee of the Henry Mayo Newhall Memorial Hospital.

更新日期：2006-07-15 00:00:00

abstract：BACKGROUND:Aggressive treatment of early stage prostate carcinoma (PC) is limited primarily to two modalities: radical prostatectomy (RP) and external beam radiation therapy (RT). The authors conducted a population-based study of Detroit area men with localized PC to determine the outcome of bowel, urinary, and sexual ...

journal_title：Cancer

authors： Schwartz K,Bunner S,Bearer R,Severson RK

更新日期：2002-07-01 00:00:00

abstract：:A 20-year-old man with previously treated lymphoblastic lymphoma, a known T-cell disorder, developed progressive disease despite intensive combination chemotherapy with doxorubicin, vincristine, and prednisone. He was subsequently treated with a 21-day course of intravenous antithymocyte globulin at a dose of approxim...

journal_title：Cancer

authors： Wong KK Jr,Sweet DL,Variakojis D

更新日期：1982-07-01 00:00:00

abstract：:Most patients with colorectal carcinoma undergo attempts at curative surgery. However, some present with metastatic disease and many others ultimately relapse. Most recurrences of colorectal cancer are not resectable and require nonsurgical approaches such as chemotherapy and radiation therapy directed against local r...

journal_title：Cancer

authors： Vaughn DJ,Haller DG

更新日期：1993-06-15 00:00:00

abstract：BACKGROUND:Trimetrexate is an antifol that differs from methotrexate in ways that may be clinically important. Because methotrexate has activity in advanced bladder cancer, this trial was initiated. METHODS:Ambulatory patients with advanced urothelial carcinoma were treated with the nonclassic antifol trimetrexate at ...

journal_title：Cancer

authors： Witte RS,Elson P,Khandakar J,Trump DL

更新日期：1994-02-01 00:00:00

abstract：:The care of patients with cancer and chronic pain, often complicated and demanding, strains the resources of a single physician. Continuity of care programs, such as that developed by the Pain Service of Memorial Sloan-Kettering Cancer Center (New York), with good communication and liaison work between hospital and co...

journal_title：Cancer

authors： Coyle N

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Although acquired somatic mutations presumably are crucial in carcinogenesis, nothing is known about the chromosome aberrations of bilateral breast carcinomas. METHODS:Eighteen specimens from 16 bilateral carcinomas were analyzed cytogenetically. The banding analysis was supplemented with fluorescence in si...

journal_title：Cancer

authors： Pandis N,Teixeira MR,Gerdes AM,Limon J,Bardi G,Andersen JA,Idvall I,Mandahl N,Mitelman F,Heim S

更新日期：1995-07-15 00:00:00

abstract：BACKGROUND:The high recurrence rate of hepatocellular carcinoma (HCC) determines the long-term prognosis for patients with HCC. In the current study, the authors tested the effects of menatetrenone, a vitamin K2 analog, on recurrent HCC and survival after curative treatment. METHODS:Sixty-one patients who were diagnos...

journal_title：Cancer

authors： Mizuta T,Ozaki I,Eguchi Y,Yasutake T,Kawazoe S,Fujimoto K,Yamamoto K

更新日期：2006-02-15 00:00:00

abstract：:Four hundred forty-seven women attending a breast clinic because of either suspicious lesions, anxiety about breast cancer, follow-up after the removal of a benign breast lesion, or a family history of breast cancer had a routine test for percentage of ferritin-bearing lymphocytes ( FBL ) in their peripheral blood. Am...

journal_title：Cancer

authors： Moroz C,Kan M,Chaimof C,Marcus H,Kupfer B,Cuckle HS

更新日期：1984-07-01 00:00:00

abstract：:This study sought to replicate and expand findings reported by the National Surgical Adjuvant Breast and Bowel Project (NSABP) on prognostic factors in resectable colon cancer. Mantel-Haenszel tests and the Cox model were used to analyze prognostic significance and effect of primary disease symptoms and tumor location...

journal_title：Cancer

authors： Steinberg SM,Barkin JS,Kaplan RS,Stablein DM

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Widespread disparities in care have been documented in women with gynecologic cancer in the United States. This study was designed to determine whether structural barriers to optimal care were present during the preoperative period for patients with gynecologic cancer. METHODS:A retrospective review was con...

journal_title：Cancer

authors： Frey MK,Moss HA,Musa F,Rolnitzky L,David-West G,Chern JY,Boyd LR,Curtin JP

更新日期：2016-03-15 00:00:00

abstract：:Sixty-three gastrectomy specimens (21 with early intestinal type carcinoma, 21 with early diffuse carcinoma, and 21 with benign nonneoplastic lesions) were examined histochemically to determine the distribution of intestinal metaplasia (IM), particularly the sulphomucin-secreting type (Type IIB IM). The frequency and ...

journal_title：Cancer

authors： Matsukuma A,Mori M,Enjoji M

更新日期：1990-08-15 00:00:00

abstract：BACKGROUND:Efforts to improve local control and survival by increasing the dose of once-daily radiation therapy beyond 70 Gray (Gy) for patients with malignant gliomas has yet been unsuccessful. Hyperfractionated radiation therapy (HF) should allow for delivery of a higher total dose without increasing normal tissue la...

journal_title：Cancer

authors： Werner-Wasik M,Scott CB,Nelson DF,Gaspar LE,Murray KJ,Fischbach JA,Nelson JS,Weinstein AS,Curran WJ Jr

更新日期：1996-04-15 00:00:00

abstract：:In order to investigate the relationship between histologic findings and clinical behavior in angioimmunoblastic lymphadenopathy (AILD), 44 patients with AILD were reviewed. These patients comprised 24 men and 20 women with age range from 25 to 84 years of age (median, 64 years). Lymphadenopathy was observed in all pa...

journal_title：Cancer

authors： Aozasa K,Ohsawa M,Fujita MQ,Kanayama Y,Tominaga N,Yonezawa T,Matsubuchi T,Hirata M,Uda H,Kanamaru A

更新日期：1989-04-15 00:00:00

abstract：:This trial determines the feasibility for patients with resectable Stages III/IV head and neck cancer who achieved a complete response to induction chemotherapy of eliminating surgery from their treatment program. Thirty patients were treated with three cycles of cisplatin and 5-fluorouracil (5-FU), followed by reendo...

journal_title：Cancer

authors： Jacobs C,Goffinet DR,Goffinet L,Kohler M,Fee WE

更新日期：1987-09-15 00:00:00

abstract：BACKGROUND:Acute myeloid leukemia (AML) with t(6;11)(q27;q23) is a well established but rare entity, and few studies have reported the full clinical, hematologic, and outcome data of patients with this disease. METHODS:To characterize the features of t(6;11) AML, the authors searched the Cancer and Leukemia Group B (C...

journal_title：Cancer

authors： Blum W,Mrózek K,Ruppert AS,Carroll AJ,Rao KW,Pettenati MJ,Anastasi J,Larson RA,Bloomfield CD

更新日期：2004-09-15 00:00:00

abstract：BACKGROUND:Conditional survival is clinically useful, particularly for patients with malignant disease who have a poor prognosis. However, there are no published data on the conditional median survival of patients with advanced carcinoma on a population basis. METHODS:Data on 217,573 patients with breast, colorectal, ...

journal_title：Cancer

authors： Kato I,Severson RK,Schwartz AG

更新日期：2001-10-15 00:00:00

abstract：:To determine the efficacy of adjuvant chemotherapy in patients with advanced head and neck squamous carcinoma, the National Cancer Institute initiated a multi-institutional, prospective randomized trial termed the Head and Neck Contracts Program. Between 1978 and 1982, 462 patients with resectable Stage III or IV canc...

journal_title：Cancer

authors：

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:During the last two decades, a rising incidence of adenocarcinoma of the esophagus has been observed in the Western world. The prognostic relevance of tumor-biological factors, such as DNA ploidy or c-erbB-2 overexpression, for overall survival following complete resection is still unknown. METHODS:In a ret...

journal_title：Cancer

authors： Nakamura T,Nekarda H,Hoelscher AH,Bollschweiler E,Harbeck N,Becker K,Siewert JR,Harbec N corrected to Harbeck N

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Children with diffuse brainstem glioma (BSG) commonly undergo novel therapies because their outcome is poor with radiation therapy (RT). Although recent clinical trials using new biologic agents documented intratumoral hemorrhage (IH) among several children with BSG, to the authors' knowledge little is known...

journal_title：Cancer

authors： Broniscer A,Laningham FH,Kocak M,Krasin MJ,Fouladi M,Merchant TE,Kun LE,Boyett JM,Gajjar A

更新日期：2006-03-15 00:00:00

abstract：:Streptococcal agent OK-432 was administered at maintenance levels with conventional inductive chemotherapeutic agents to stage III and IV lung cancer patients. Survival rates were longer in patients treated with OK-432 than in patients treated without OK-432. An enhancement of lymphocyte blastogenic activity and a del...

journal_title：Cancer

authors： Kimura I,Ohnoshi T,Yasuhara S,Sugiyama M,Urabe Y

更新日期：1976-05-01 00:00:00

abstract：BACKGROUND:The AJCC staging system and post-operative nomograms use patient and tumor characteristics to provide prognostic estimates after resection of retroperitoneal sarcoma (RPS). While these variables help to predict survival at the time of diagnosis and resection, the applicability of these prognostic factors to ...

journal_title：Cancer

authors： Abbott AM,Habermann EB,Parsons HM,Tuttle T,Al-Refaie W

更新日期：2012-07-01 00:00:00