Vincristine, dactinomycin, and cyclophosphamide in the treatment of malignant germ cell tumors of the ovary. A Gynecologic Oncology Group Study (a final report).

abstract：:Deguelin is a rotenoid compound that exists in abundant quantities in the bark, roots, and leaves of the Leguminosae family of plants. An analysis of evidence from both in vitro and in vivo studies suggests that deguelin displays potent anticancer activity against multiple cancer types and exhibits chemopreventive pot...

journal_title：Cancer

authors： Varughese RS,Lam WS,Marican AABH,Viganeshwari SH,Bhave AS,Syn NL,Wang J,Wong AL,Kumar AP,Lobie PE,Lee SC,Sethi G,Goh BC,Wang L

更新日期：2019-06-01 00:00:00

abstract：:Flow cytometric analysis of nuclear DNA content was performed on excised malignant tissue of the esophagus. The DNA ploidy pattern was compared with a variety of histologic parameters and the subsequent clinical course to determine whether or not this pattern is associated with the mode of malignant potentiality. Of t...

journal_title：Cancer

authors： Kaketani K,Saito T,Kobayashi M

更新日期：1989-08-15 00:00:00

abstract：:Records of 100 consecutive hospitalized cancer patients referred for psychiatric consultation were reviewed. These patients constituted only 5% of those seen by the Psychiatry Consultation Service during the study period. Fifty-six percent of the referred patients were diagnosed as depressed and 40% as having organic ...

journal_title：Cancer

authors： Levine PM,Silberfarb PM,Lipowski ZJ

更新日期：1978-09-01 00:00:00

abstract：:Chemotherapy for tumors of the central nervous system has a limited efficacy presumably because of restricted blood-brain barrier permeability. The advantage of regional intra-arterial administration of anticancer drugs is an increased uptake during the first passage of the drugs through tumor capillaries. Twenty pati...

journal_title：Cancer

authors： Madajewicz S,Chowhan N,Iliya A,Roque C,Beaton R,Davis R,Fertman S,Meek A,Alvarez O,Pampati M

更新日期：1991-06-01 00:00:00

abstract：:Breast fluid was collected from 244 nonlactating Finnish women with no known breast disease and analyzed with respect to various epidemiologic and hormonal parameters commonly associated with breast cancer risk. The data obtained permit characterization of women with breast secretory ability and provide fundamental in...

journal_title：Cancer

authors： Wynder EL,Hill P,Laakso K,Littner R,Kettunen K

更新日期：1981-03-15 00:00:00

abstract：:The anniversary of the first publication of Cancer provides an opportunity to review the progress in liver cancer surgery in the past 60 years. Indeed, the past half century has been witness to remarkable advances in liver surgery that have provided benefit to so many patients afflicted with primary or secondary liver...

journal_title：Cancer

authors： Tanabe KK

更新日期：2008-10-01 00:00:00

abstract：:The properties of two classes of nonhistone nuclear proteins (NHNP) whose appearance has been correlated with the process of carcinogenesis in the colonic epithelium of rats given 1,2-dimethylhydrazine (DMH) have been investigated. NHNP isolated from adenocarcinomas of the colon were tested for their binding to homolo...

journal_title：Cancer

authors： Boffa LC,Allfrey VG

更新日期：1977-11-01 00:00:00

abstract：BACKGROUND:Idarubicin (IDR), an anthracycline that is a derivative of daunorubicin, was synthesized in an attempt to find new analogs of daunorubicin with an improved spectrum of activity and diminished acute or chronic toxicity. Because of the favorable pharmacokinetic profile of IDR (with the persistence of its activ...

journal_title：Cancer

authors： Arndt CA,Krailo MD,Steinherz L,Scheithauer B,Liu-Mares W,Reaman GH

更新日期：1998-08-15 00:00:00

abstract：BACKGROUND:Cyclin-dependent kinases (CDK) and cyclins constitute the subunits of the maturation-promoting factor that controls the process of cell division. High levels of these proteins have been reported in human malignancies of the stomach, colon, breast, and lung, and have been implicated in aberrant cell division ...

journal_title：Cancer

authors： Kallakury BV,Sheehan CE,Ambros RA,Fisher HA,Kaufman RP Jr,Ross JS

更新日期：1997-08-15 00:00:00

abstract：BACKGROUND:It has been shown that adoptive immunotherapy with Epstein-Barr virus (EBV)-specific cytotoxic T-lymphocytes (CTL) is effective for the treatment of EBV-induced lymphoproliferative disease in stem cell transplantation recipients and organ transplantation recipients. The role of EBV CTL in other tumors for wh...

journal_title：Cancer

authors： Lucas KG,Salzman D,Garcia A,Sun Q

更新日期：2004-05-01 00:00:00

abstract：:Tumor-specific DNA sequences or unique sequences have been found in a number of human cancer cells including gliomas but not in equivalent normal cells. In a continuing effort to further elucidate the nature of these sequences, thermal analysis using the hydroxyapatite technique was carried out on the various grades o...

journal_title：Cancer

authors： Cuatico W

更新日期：1980-07-15 00:00:00

abstract：BACKGROUND:Informed consent has been proposed as the optimal method for ensuring the ethical entry of patients into clinical trials. However, it is known that problems with informed consent exist from the perspective of both patients and physicians. This has led to the suggestion that a third party, such as a research ...

journal_title：Cancer

authors： Loh WY,Butow PN,Brown RF,Boyle F

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Some patients with chronic myeloid leukemia (CML) have a history of previous malignancies. To the authors' knowledge, outcomes for CML diagnosed in these patients have not been well described. The current study was conducted to determine the outcome of patients with CML and a history of prior malignancies. ...

journal_title：Cancer

authors： Koller PB,Kantarjian HM,Nogueras-Gonzalez GM,Jabbour E,Verstovsek S,Borthakur G,Estrov Z,Wierda WG,Garcia-Manero G,Ferrajoli A,Ravandi F,O'Brien SM,Cortes JE

更新日期：2017-02-15 00:00:00

abstract：BACKGROUND:Polymorphic reticulosis, a type of lethal midline granuloma (LMG), has been referred to as nasal T-cell lymphoma (NTL) because of its proliferating cells' positive reactivity to anti-T-lymphocyte antibodies. Recently, several studies have suggested that proliferating cells in NTL may be natural killer (NK) i...

journal_title：Cancer

authors： Aozasa K,Ohsawa M,Tomita Y,Tagawa S,Yamamura T

更新日期：1995-02-01 00:00:00

abstract：:The National Breast and Cervical Cancer Early Detection Program (NBCCEDP) of the Centers for Disease Control and Prevention (CDC) is implemented through cooperative agreements with state health departments, US territories, and tribal health organizations (grantees). Grantees typically contract with clinicians and othe...

journal_title：Cancer

authors： Yancy B,Royalty JE,Marroulis S,Mattingly C,Benard VB,DeGroff A

更新日期：2014-08-15 00:00:00

abstract：:Correlations of c-erbB-2 protein expression with clinical outcomes of gastric carcinomas were studied in 189 gastric carcinomas. There were 23 (12.2%) carcinomas with evidence of c-erbB-2 protein in which the reaction was localized to the cell membrane. There was no significant association between c-erbB-2 staining an...

journal_title：Cancer

authors： Yonemura Y,Ninomiya I,Ohoyama S,Kimura H,Yamaguchi A,Fushida S,Kosaka T,Miwa K,Miyazaki I,Endou Y

更新日期：1991-06-01 00:00:00

abstract：:A 21-year-old male with Ph1 positive acute myeloid leukemia (AML) became constipated, experienced pain in the sacral area and retained urine. These were the principle presenting complaints of his disease. With local radiotherapy and systemic chemotherapy, all neurologic symptoms and signs disappeared within three days...

journal_title：Cancer

authors： Petursson SR,Boggs DR

更新日期：1981-01-15 00:00:00

abstract：BACKGROUND:Low socioeconomic status (SES) is a reported risk factor for cervical carcinoma, but few studies have taken into account adequately the possibly confounding effects of oncogenic human papillomavirus (HPV) infection as well as access to screening and subsequent treatment. METHODS:Women (n = 5060 women) with ...

journal_title：Cancer

authors： Khan MJ,Partridge EE,Wang SS,Schiffman M

更新日期：2005-07-01 00:00:00

abstract：:Multiple independent tumors were identified in specimens from 117 of 234 prostatectomies for clinical adenocarcinoma; there were 266 incidental cancers in these 117 prostates. The clinically detected carcinoma was the largest (or only) tumor in all 202 Stage B cases. However, among 32 Stage A cases (detection by trans...

journal_title：Cancer

authors： Villers A,McNeal JE,Freiha FS,Stamey TA

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Factors that could optimize the management of pediatric spinal cord astrocytoma remain unclear and controversial. METHODS:To determine the factors that influence the prognosis of pediatric patients with spinal cord astrocytomas, a series of 73 consecutive patients at 13 French treatment centers with histolo...

journal_title：Cancer

authors： Bouffet E,Pierre-Kahn A,Marchal JC,Jouvet A,Kalifa C,Choux M,Dhellemmes P,Guérin J,Tremoulet M,Mottolese C

更新日期：1998-12-01 00:00:00

abstract：:The histories of 121 Stage II melanoma patients were reviewed to determine the value of monitoring serum LDH in postoperative follow-up examinations. Charts of 58 Stage III patients who had autopsies at UCLA also were reviewed to define the relationship between an elevated LDH and liver metastases. The sensitivity and...

journal_title：Cancer

authors： Finck SJ,Giuliano AE,Morton DL

更新日期：1983-03-01 00:00:00

abstract：:A review of over 400 primary bone tumors yielded 11 lesions with features allowing classification as malignant fibrous histiocytoma on a purely histological basis. Correlation with roentgenograms and clinical data indicated that these tumors occurred as osteolytic lesions associated with a high incidence of pathologic...

journal_title：Cancer

authors： Spanier SS,Enneking WF,Enriquez P

更新日期：1975-12-01 00:00:00

abstract：:An exceedingly rare tumor arising in the upper lateral vagina is described histologically, histochemically, and ultrastructurally. It is compared to the lesion reported by Okagaki et al. which is considered to represent the same type of tumor. Comparison with synovial sarcomas indicates that the lesion is similar, but...

journal_title：Cancer

authors： Shevchuk MM,Fenoglio CM,Lattes R,Frick HC 2nd,Richart RM

更新日期：1978-07-01 00:00:00

abstract：:Proviral DNA of adult T-cell leukemia virus (HTLV-I) was examined by the standard Southern blotting method in lymph nodes of 45 patients with anti-HTLV-I antibody (ATLA)-positive adult T-cell leukemia/lymphoma (ATLL). Six of these patients revealed no monoclonal proviral HTLV-I DNA in tumor cells. These six patients s...

journal_title：Cancer

authors： Yoshida T,Kikuchi M,Ooshima K,Takeshita M,Kimura N,Kozuru M,Satoh H

更新日期：1989-12-15 00:00:00

abstract：:Data from a hospital-based case-control study between 1985-1990 were used to examine the effects of tobacco, alcohol, asbestos, and other occupational exposures on laryngeal cancer risk in 194 white men with primary cancer of the larynx and 184 age-matched control subjects. A dose-dependent effect for current cigarett...

journal_title：Cancer

authors： Muscat JE,Wynder EL

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:The optimal use of radiation therapy for cancer treatment is hampered by the application of tolerance limits of normal tissues derived empirically from population averages. Such limits do not reflect the considerable differences from patient to patient in susceptibility to late radiation sequelae. Assays tha...

journal_title：Cancer

authors： Peters LJ

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:Bortezomib has preclinical and clinical in B-cell lymphomas, both alone and in combination with other agents. A phase 1 evaluation was conducted of bortezomib with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in patients with untreated diffuse large B-cell lymphoma (DLBC...

journal_title：Cancer

authors： Furman RR,Martin P,Ruan J,Cheung YK,Vose JM,LaCasce AS,Elstrom R,Coleman M,Leonard JP

更新日期：2010-12-01 00:00:00

abstract：:The prevalence of variant alkaline phosphatase in the serum of 335 southern African blacks with hepatocellular carcinoma was determined using polyacrylamide gel electrophoresis. The isoenzyme was detected in 2% (seven of 335) of the patients: it could not be found in the serum of 300 matched, healthy individuals or in...

journal_title：Cancer

authors： Bukofzer S,Kew MC,Rowe P

更新日期：1988-09-01 00:00:00

abstract：:A growing body of research shows that a majority of patients with cancer report having religious and spiritual (R/S) beliefs, engaging in R/S behaviors, or deriving comfort from R/S experiences. These studies have been reviewed but not subjected to rigorous critical analysis. A meta-analytic approach is needed to prov...

journal_title：Cancer

authors： Salsman JM,Fitchett G,Merluzzi TV,Sherman AC,Park CL

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:An estimated 5-10% of all pancreatic adenocarcinomas have a hereditary association. The objective of the current study was to characterize the clinical and pathologic features of familial pancreatic carcinoma and to determine potential differences in demographics, risk factors, and outcomes between familial ...

journal_title：Cancer

authors： James TA,Sheldon DG,Rajput A,Kuvshinoff BW,Javle MM,Nava HR,Smith JL,Gibbs JF

更新日期：2004-12-15 00:00:00