Spinal cord involvement in leukemia: a review of the literature and a case of Ph1+ acute myeloid leukemia presenting with a conus medullaris syndrome.

abstract：:The clinical courses of 64 patients undergoing abdominoperineal resection for Stage I lower rectal carcinoma (tumors confined to the muscularis propria without lymph node involvement) were reviewed to identify subsets at risk for failure. Twelve of 12 patients with tumors limited to the submucosa remained disease free...

journal_title：Cancer

authors： Willett CG,Lewandrowski K,Donnelly S,Shellito PC,Convery K,Eliseo R,Compton CC

更新日期：1992-04-01 00:00:00

abstract：:One hundred thirty-nine consecutive unselected adults with acute nonlymphoblastic leukemia were treated with a high-dose chemotherapeutic remission-induction regimen consisting of daunomycin (70 mg/m2 IV on days 1, 2, 3), cytosine arabinoside (100 mg/m2 IV every 12 hours), 6-thioguanine (100 mg/m2 orally every 12 hour...

journal_title：Cancer

authors： Glucksberg H,Cheever MA,Farewell VT,Fefer A,Sale GE,Thomas ED

更新日期：1981-09-01 00:00:00

abstract：BACKGROUND:Traditional single-marker and multimarker molecular profiling approaches in bladder cancer do not account for major risk factors and their influence on clinical outcome. This study examined the prognostic value of molecular alterations across all disease stages after accounting for clinicopathological factor...

journal_title：Cancer

authors： Mitra AP,Castelao JE,Hawes D,Tsao-Wei DD,Jiang X,Shi SR,Datar RH,Skinner EC,Stein JP,Groshen S,Yu MC,Ross RK,Skinner DG,Cortessis VK,Cote RJ

更新日期：2013-02-15 00:00:00

abstract：BACKGROUND:Some studies have suggested that the use of calcium channel blockers may increase the risk of cancer. A possible association of the use of calcium channel blockers with cancer incidence and cancer mortality was addressed using data from the Nurses' Health Study. METHODS:In this study, a total of 18,635 fema...

journal_title：Cancer

authors： Michels KB,Rosner BA,Walker AM,Stampfer MJ,Manson JE,Colditz GA,Hennekens CH,Willett WC

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:This qualitative study investigated the medical decision-making preferences of adolescent oncology patients and the parental and clinician behaviors that adolescents report to be supportive of their preferred level of decision-making involvement. METHODS:Interviews were conducted with 40 adolescents between...

journal_title：Cancer

authors： Weaver MS,Baker JN,Gattuso JS,Gibson DV,Sykes AD,Hinds PS

更新日期：2015-12-15 00:00:00

abstract：:Chemotherapy once relegated to end stage patients has markedly improved with the use of combinations. Response rates with single agents have improved from 15 to 35%, to 50 to 70%, using combinations with an increase in complete response rates to about 25%. A series of four studies completed by the Eastern Cooperative ...

journal_title：Cancer

authors： Carbone PP,Bauer M,Band P,Tormey D

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated an association between a diagnosis of cancer and the risk of suicide; however, they failed to account for psychiatric care before a cancer diagnosis, which may confound this relationship. The objective of this study was to assess the effect of a cancer diagnosis on the risk...

journal_title：Cancer

authors： Klaassen Z,Wallis CJD,Chandrasekar T,Goldberg H,Sayyid RK,Williams SB,Moses KA,Terris MK,Nam RK,Urbach D,Austin PC,Kurdyak P,Kulkarni GS

更新日期：2019-08-15 00:00:00

abstract：BACKGROUND:Accelerated radiotherapy (RT) represents a promising method with which to improve the treatment outcome in patients with head and neck carcinoma. However, its applicability to elderly patients has not been well established. This study assessed treatment toxicities, patient compliance, and oncologic results i...

journal_title：Cancer

authors： Allal AS,Maire D,Becker M,Dulguerov P

更新日期：2000-02-01 00:00:00

abstract：:Many clinicians use group support to reduce the psychosocial difficulties of persons with cancer. This study compared the long-term benefits of a thematic counseling model used both as a structure for group support and for counseling patients individually. The thematic model included eight counseling sessions focused ...

journal_title：Cancer

authors： Cain EN,Kohorn EI,Quinlan DM,Latimer K,Schwartz PE

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND:The current study was designed to evaluate the efficacy and toxicity of the continuous oral administration of a combination of cyclophosphamide (50 mg/day given in the morning) and dexamethasone (1 mg/day given in the evening) in patients with prostate specific antigen (PSA) progression despite single or mul...

journal_title：Cancer

authors： Glode LM,Barqawi A,Crighton F,Crawford ED,Kerbel R

更新日期：2003-10-15 00:00:00

abstract：BACKGROUND:Previous research has demonstrated that many lung cancer survivors report difficulties with symptom control and experience a poor quality of life (QOL). Although recent studies have suggested a relationship of single nucleotide polymorphisms (SNPs) in several cytokine genes with cancer susceptibility and pro...

journal_title：Cancer

authors： Rausch SM,Clark MM,Patten C,Liu H,Felten S,Li Y,Sloan J,Yang P

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:In view of the many studies of early stage colorectal carcinoma from Japan, it is essential to know whether the criteria for the histologic diagnosis of colorectal carcinoma are similar in Japan and Western countries. METHODS:Eight expert pathologists from Japan (4), North America (2), and Europe (2) indivi...

journal_title：Cancer

authors： Schlemper RJ,Itabashi M,Kato Y,Lewin KJ,Riddell RH,Shimoda T,Sipponen P,Stolte M,Watanabe H

更新日期：1998-01-01 00:00:00

abstract：:The field of chemical carcinogenesis is reviewed, with emphasis on three aspects: 1) environmental chemicals are a major cause of human cancer; 2) most chemical carcinogens require metabolic activation by mixed-function oxidases to electrophilic metabolites that form strong covalent chemical bonds with cellular macrom...

journal_title：Cancer

authors： Heidelberger C

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND:The National Lung Screening Trial (NLST), which was conducted between 2002 and 2009, demonstrated that screening with low-dose computed tomography (LDCT) reduced lung cancer mortality by 20% among screening-eligible populations compared with chest x-ray. In this article, the authors provide an estimate of th...

journal_title：Cancer

authors： Ma J,Ward EM,Smith R,Jemal A

更新日期：2013-04-01 00:00:00

abstract：:The serum lactase dehydrogenase (LDH) of 56 patients with Ewing's sarcoma was examined to determine the use of LDH as a tumor marker. The initial LDH level was used to determine its ability to predict survival. The follow-up LDH level also was examined, as an indicator of recurrent disease. The initial LDH level was f...

journal_title：Cancer

authors： Farley FA,Healey JH,Caparros-Sison B,Godbold J,Lane JM,Glasser DB

更新日期：1987-04-01 00:00:00

abstract：:The study is a clinicopathologic report on 64 patients with primary adenocarcinoma of the urinary bladder and urachus, with particular reference to important prognostic and therapeutic factors. All tumors exhibited adenocarcinomatous features in at least two thirds of the examined tumor area. Pure forms of the differe...

journal_title：Cancer

authors： Anderström C,Johansson SL,von Schultz L

更新日期：1983-10-01 00:00:00

abstract：:Adjuvant systemic treatments have greatly improved the prognosis of women with early breast cancer. Combination chemotherapy and, for patients with oestrogen receptor-positive (ER+) tumours, endocrine treatment has been found to reduce the frequency of relapse and improve survival. New adjuvant strategies include the ...

journal_title：Cancer

authors： Coleman RE

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:The spontaneous formation of neutralizing antibodies (inhibitors) to factor VIII (FVIII) in patients with cancer is a well known phenomenon. However, to the authors' knowledge there is lack of information in the literature with respect to the clinical course of these patients and the nature of the associatio...

journal_title：Cancer

authors： Sallah S,Wan JY

更新日期：2001-03-15 00:00:00

abstract：:A case of fulminant hepatic failure leading to death in a patient receiving DTIC for metastatic melanoma is presented. Autopsy revealed widespread centrilobular necrosis secondary to a veno-occlusive process. There was no evidence of a similar process in other organs, and common causes of similar pathology were ruled ...

journal_title：Cancer

authors： Asbury RF,Rosenthal SN,Descalzi ME,Ratcliffe RL,Arseneau JC

更新日期：1980-05-15 00:00:00

abstract：BACKGROUND:The usefulness of fine-needle aspiration biopsy (FNAB) for the histologic subtyping of specific sarcomas still is somewhat controversial but is becoming increasingly popular in the U.S. METHODS:To determine the accuracy and usefulness of FNAB in the differential diagnosis of myxoid sarcoma, the authors retr...

journal_title：Cancer

authors： Kilpatrick SE,Ward WG,Bos GD

更新日期：2000-06-25 00:00:00

abstract：BACKGROUND:Cancer affects patients' incomes, but to the authors' knowledge few studies to date have examined how the income of the patients' spouses may be influenced. In this population-based study from Norway, the effects of cancer on both partners' earnings are analyzed. METHODS:The difference between labor earning...

journal_title：Cancer

authors： Syse A,Tretli S,Kravdal O

更新日期：2009-09-15 00:00:00

abstract：BACKGROUND:The effects of relaxin (RLX) on the human breast adenocarcinoma cell line MCF-7 have been evaluated. METHODS:The cells were maintained in culture with Dulbecco's modified Eagle's medium with 1% and 10% fetal calf serum. Highly purified porcine RLX was added at concentrations ranging between 10(-11) and 10(-...

journal_title：Cancer

authors： Bigazzi M,Brandi ML,Bani G,Sacchi TB

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Tamoxifen and aminoglutethimide are two hormone therapies reported to be effective palliative approaches for patients with metastatic breast cancer. The current trial was designed to evaluate their relative therapeutic effectiveness. METHODS:Two hundred forty-nine postmenopausal women with advanced breast c...

journal_title：Cancer

authors： Gale KE,Andersen JW,Tormey DC,Mansour EG,Davis TE,Horton J,Wolter JM,Smith TJ,Cummings FJ

更新日期：1994-01-15 00:00:00

abstract：:Actual HL-A typing has been performed on 115 members of cancer family N, a large kindred (over 1000 members ascertained) showing the findings consistent with the cancer family syndrome. In the cancer-prone line (branches C and D) of the family, 20 of 21 members with cancer had one HL-A haplotype, HL-A2-HL-A12 (relativ...

journal_title：Cancer

authors： Lynch HT,Thomas RJ,Terasaki PI,Ting A,Guirgis HA,Kaplan AR,Magee H,Lynch J,Kraft C,Chaperon E

更新日期：1975-10-01 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) plays an important role in the process of lymphocyte-mediated cytotoxicity against malignant cells. Osteoprotegerin (OPG) is a soluble decoy receptor for TRAIL, and circulating OPG has been implicated in the protection of cells from TRAIL-mediat...

journal_title：Cancer

authors： Mizutani Y,Matsubara H,Yamamoto K,Nan Li Y,Mikami K,Okihara K,Kawauchi A,Bonavida B,Miki T

更新日期：2004-10-15 00:00:00

abstract：:Fifty-three patients with advanced lymphocytic lymphoma were randomly assigned to treatment with the combination cyclophosphamide, vincristine, and prednisone (CVP) or the same agents used successively in maximal doses (C-V-P). Complete remissions occurred in 68% with CVP and 48% with C-V-P. For patients with nodular ...

journal_title：Cancer

authors： Kennedy BJ,Bloomfield CD,Kiang DT,Vosika G,Peterson BA,Theologides A

更新日期：1978-01-01 00:00:00

abstract：:POEMS syndrome is a rare multisystem affliction known for its signs, from which it also takes its acronym name "peripheral neuropathy, organomegaly, endocrinopathy, monoclonal (M) protein, and skin lesions." Our study chronicles the course of this syndrome in a young woman with Castleman's disease (angiofollicular lym...

journal_title：Cancer

authors： Mandler RN,Kerrigan DP,Smart J,Kuis W,Villiger P,Lotz M

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND:In the phase 3 MARIANNE trial, trastuzumab emtansine (T-DM1) with or without pertuzumab showed noninferior progression-free survival and better tolerability than trastuzumab plus a taxane (HT) for the first-line treatment of human epidermal growth factor receptor 2 (HER2)-positive advanced breast cancer. Thi...

journal_title：Cancer

authors： Perez EA,Barrios C,Eiermann W,Toi M,Im YH,Conte P,Martin M,Pienkowski T,Pivot XB,Burris HA 3rd,Petersen JA,De Haas S,Hoersch S,Patre M,Ellis PA

更新日期：2019-11-15 00:00:00

abstract：:Numerous examples exist of prognostic factors that have been conclusively established and that can segregate the target patient population into subgroups with vastly different outcomes. At the same time, we can expect, in the majority of trials being conducted, that if a new treatment turns out to be successful, it ge...

journal_title：Cancer

authors： Sather HN

更新日期：1986-07-15 00:00:00

abstract：BACKGROUND:Prior studies raise concern about gender bias in cancer research, including insufficient inclusion of women or men, or studying women and men differently. The 1993 National Institutes of Health Revitalization Act aimed to eliminate gender bias in medicine. To examine changes in medical and psychological lite...

journal_title：Cancer

authors： Hoyt MA,Rubin LR

更新日期：2012-10-01 00:00:00