Gender representation of cancer patients in medical treatment and psychosocial survivorship research: changes over three decades.

abstract：BACKGROUND:Two evidence-based therapies exist for the treatment of high-risk prostate cancer (PCA): external-beam radiotherapy (RT) with hormone therapy (H) (RT + H) and radical prostatectomy (S) with adjuvant radiotherapy (S + RT). Each of these strategies is associated with different rates of local control, distant m...

journal_title：Cancer

authors： Parikh R,Sher DJ

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:BRAF inhibitors are effective in melanoma and other cancers with BRAF mutations; however, patients ultimately develop therapeutic resistance through the activation of alternative signaling pathways such as RAF/RAS or MET. The authors hypothesized that combining the BRAF inhibitor vemurafenib with either the ...

journal_title：Cancer

authors： Janku F,Sakamuri D,Kato S,Huang HJ,Call SG,Naing A,Holley VR,Patel SP,Amaria RN,Falchook GS,Piha-Paul SA,Zinner RG,Tsimberidou AM,Hong DS,Meric-Bernstam F

更新日期：2021-02-01 00:00:00

abstract：:Mesenchymal chondrosarcoma of bone and soft tissues treated at the Istituto Ortopedico Rizzoli are reviewed. The skeletal locations were prominent in five cases. Only two cases were in the soft tissues. Radiographic picture in the bone shows an aggressive osteolysis, with soft tissues invasion. Histologic picture is t...

journal_title：Cancer

authors： Bertoni F,Picci P,Bacchini P,Capanna R,Innao V,Bacci G,Campanacci M

更新日期：1983-08-01 00:00:00

abstract：:Turcot's syndrome is a rare, genetically transmittable disease in which patients with colonic polyposis (possibly complicated by the progression to adenocarcinoma) have malignant central nervous system neoplasms. Dominant, recessive, and sporadic cases have been described. A 26-year-old man is reported with no relevan...

journal_title：Cancer

authors： Newton HB,Rosenblum MK,Malkin MG

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:In patients with locoregional carcinoma of the esophagus or esophagogastric junction who underwent preoperative chemoradiation, it is unclear whether survival was better predicted by pretherapy clinical stage or by posttherapy pathologic stage. METHODS:The authors studied 235 consecutive patients with preth...

journal_title：Cancer

authors： Chirieac LR,Swisher SG,Ajani JA,Komaki RR,Correa AM,Morris JS,Roth JA,Rashid A,Hamilton SR,Wu TT

更新日期：2005-04-01 00:00:00

abstract：BACKGROUND:Recent clinical studies have demonstrated that tumor angiogenesis is a potent prognostic indicator for breast cancer patients. The quantitation of endothelial growth factors is thought to be useful to assess angiogenic phenotype in the tumor. Among the many new endothelial growth factors, vascular endothelia...

journal_title：Cancer

authors： Toi M,Kondo S,Suzuki H,Yamamoto Y,Inada K,Imazawa T,Taniguchi T,Tominaga T

更新日期：1996-03-15 00:00:00

abstract：:One hundred eighty-nine patients received a four-drug combination consisting of cyclophosphamide, Oncovin (vincristine), methyl CCNU, and bleomycin (COMB), according to three different drug regimens, performed sequentially. Of the 189, 62 had a partial response (33%) including 11/33 with squamous lung cancer, 11/32 wi...

journal_title：Cancer

authors： Livingston RB,Einhorn LH,Bodey GP,Burgess MA,Freireich EJ,Gottlieb JA

更新日期：1975-08-01 00:00:00

abstract：BACKGROUND:Data suggest that vitamin D plays a role in the treatment and prevention of prostate cancer. The combination of high-dose, intermittent calcitriol (1,25 dihydroxyvitamin D3) plus dexamethasone was studied based on evidence that dexamethasone potentiates the antitumor effects of calcitriol and ameliorates hyp...

journal_title：Cancer

authors： Trump DL,Potter DM,Muindi J,Brufsky A,Johnson CS

更新日期：2006-05-15 00:00:00

abstract：BACKGROUND:The ability of screening mammography programs serving women of different socioeconomic status (SES) to diagnose early stage breast carcinoma in a comparably effective fashion has been questioned. METHODS:Results of screening 50,653 women of lower SES were compared with those of screening 45,923 more socioec...

journal_title：Cancer

authors： Dershaw DD,Loring L,True SJ,Momrow DC,Liberman L,Morris EA

更新日期：1998-05-01 00:00:00

abstract：:The circulating levels of four tumor- or trophoblast-associated antigens were measured by specific radioimmunoassays in 11 patients with gestational choriocarcinoma. The estimations were carried out at the time when the urinary gonadotropin (hCG) excretion was low or negligible. Gonadotropin, measured as the hCG beta-...

journal_title：Cancer

authors： Seppälä M,Rutanen EM,Ranta T,Aho I,Nieminen U,Unnérus HA,Saksela E

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:Vascular endothelial growth factor receptor-1 (VEGFR-1) is one of three receptor tyrosine kinases for VEGF, a key regulator of angiogenesis in cancer. Although VEGFRs initially were believed to be expressed exclusively on endothelial cells (ECs), recent studies have demonstrated the presence of VEGFR-1 on no...

journal_title：Cancer

authors： Wey JS,Fan F,Gray MJ,Bauer TW,McCarty MF,Somcio R,Liu W,Evans DB,Wu Y,Hicklin DJ,Ellis LM

更新日期：2005-07-15 00:00:00

abstract：BACKGROUND:Thalidomide is an antiangiogenic agent with immune modulating potential. The objective of this study was to determine response rates among women who were treated for recurrent ovarian cancer using topotecan with or without thalidomide. METHODS:Women were enrolled in this multicenter, prospective, randomized...

journal_title：Cancer

authors： Downs LS Jr,Judson PL,Argenta PA,Ghebre R,Geller MA,Bliss RL,Boente MP,Nahhas WA,Abu-Ghazaleh SZ,Chen MD,Carson LF

更新日期：2008-01-15 00:00:00

abstract：BACKGROUND:Lesions of the thyroid gland composed of Hurthle cells encompass pathologic entities ranging from hyperplastic nodules with Hurthle cell metaplasia to Hurthle cell carcinomas. The cytologic distinction between these entities can be diagnostically challenging. Many cytologic features of Hurthle cell lesions t...

journal_title：Cancer

authors： Elliott DD,Pitman MB,Bloom L,Faquin WC

更新日期：2006-04-25 00:00:00

abstract：BACKGROUND:The influence of HER-2/neu on prognosis of breast cancer is controversial. The authors investigated by immunohistochemistry in node-positive disease the influence of the pattern of immunostaining (membranous or cytoplasmic) on outcome and the prognostic significance of this marker in patients receiving or no...

journal_title：Cancer

authors： Têtu B,Brisson J

更新日期：1994-05-01 00:00:00

abstract：:A case is presented of a man with ulcerating skin nodules who was diagnosed by histologic and immunohistologic analysis of skin biopsy specimens as having lymphomatoid granulomatosis (LYG). Phenotypic studies showed the majority of the infiltrating cells to be activated CD4+ T-lymphocytes. The disease followed a rapid...

journal_title：Cancer

authors： Atkinson CH,Davis AL,Colls BM,Wolever TH,Burry AF,Hart DN

更新日期：1989-02-15 00:00:00

abstract：BACKGROUND:Gastrointestinal stromal tumors (GISTs) are a specific clinicopathologic entity characterized by activating mutations in the c-KIT gene. These mutations are associated with increased immunohistochemical staining for the c-KIT protein. Because many GISTs display a definitive response to the KIT inhibitor imat...

journal_title：Cancer

authors： Willmore-Payne C,Layfield LJ,Holden JA

更新日期：2005-06-25 00:00:00

abstract：:This article reviews the clinicopathologic features and the biological behavior of 24 cases of synovial sarcoma that took origin from the cervical prevertebral connective tissue space and manifested as a retropharyngeal tumor or as a palpable mass in the anterior or posterior cervical triangle. The age of the 24 patie...

journal_title：Cancer

authors： Roth JA,Enzinger FM,Tannenbaum M

更新日期：1975-04-01 00:00:00

abstract：BACKGROUND:Although thin cutaneous melanomas generally have a favorable prognosis, in some cases they may undergo progression. The current study was undertaken to identify variables that may predict a more aggressive clinical outcome in these patients. In addition to classic clinicopathologic features, the authors test...

journal_title：Cancer

authors： Massi D,Franchi A,Borgognoni L,Reali UM,Santucci M

更新日期：1999-03-01 00:00:00

abstract：:Interest in the elderly population, persons 65 years of age or older, as a target group for cancer control has not been great. Age recommendations rarely are made for prevention and early detection of cancer for elderly persons. However, cancer incidence and mortality rates are known to rise rapidly with increasing ag...

journal_title：Cancer

authors： Yancik R,Kessler L,Yates JW

更新日期：1988-10-15 00:00:00

abstract：:The authors report the accuracy of mammographically guided fine-needle aspiration (FNA) for the diagnosis of nonpalpable breast lesions in a series of 71 patients. Each mammographically guided FNA was immediately followed by hookwire localization and open biopsy. Seven malignancies were identified cytologically, but t...

journal_title：Cancer

authors： Layfield LJ,Parkinson B,Wong J,Giuliano AE,Bassett LW

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:The purpose of the current study was to determine the frequency of 'probably benign' interpretations at breast magnetic resonance (MR) imaging screening of high-risk women and the frequency of subsequent malignancy in these women. METHODS:The authors performed a retrospective review of the records of 367 as...

journal_title：Cancer

authors： Liberman L,Morris EA,Benton CL,Abramson AF,Dershaw DD

更新日期：2003-07-15 00:00:00

abstract：:Thirteen patients with a variety of advanced gynecologic malignancies were administered BCG via the dorsal lymphatics of the lower extremity in addition to standard accepted forms of therapy. Prolonged febrile courses, lymphangitis and suppurative adenitis were observed along the lymphatic pathway of the injected lowe...

journal_title：Cancer

authors： Mangan C,Jeglum KA,Sedlacek TV,Giuntoli RL,Wheeler JE,Rubin E,Mikuta JJ

更新日期：1977-12-01 00:00:00

abstract：:Activities of glucosephosphate isomerase, lactate dehydrogenase, and NADP-isocitrate dehydrogenase were significantly elevated in breast cancer specimens from patients who responded favorably to combination cytotoxic chemotherapy regimens compared with those in carcinomas from patients failing to respond to the same c...

journal_title：Cancer

authors： Hilf R,Savlov ED,Rector WD,Wittliff JL

更新日期：1976-08-01 00:00:00

abstract：BACKGROUND:Louisiana is one of the few Southern states that enacted the Medicaid expansion of the Patient Protection and Affordable Care Act (ACA). To the authors' knowledge, the issue of how this has affected the breast cancer landscape in Louisiana is unknown. The authors have postulated that ACA expansion had a posi...

journal_title：Cancer

authors： Chu QD,Li T,Hsieh MC,Yi Y,Gibbs JF,Lyons JM 3rd,Wu XC

更新日期：2020-11-03 00:00:00

abstract：BACKGROUND:Human papillomaviruses (HPVs) commonly cause proliferative lesions of squamous epithelia, and infection with certain HPV types carries a high risk of malignant transformation, especially in the uterine cervix but also at other sites, including the esophagus. We used molecular techniques to detect and type HP...

journal_title：Cancer

authors： West AB,Soloway GN,Lizarraga G,Tyrrell L,Longley JB

更新日期：1996-06-15 00:00:00

abstract：:Racial differences in the risk of cancer of the urinary bladder associated with cigarette smoking and alcohol consumption were examined in a study of 1663 cases (1534 whites and 129 blacks) and 4930 controls matched 3:1 by sex, race, and age to the cases. Significant increases in cancer risk associated with cigarette ...

journal_title：Cancer

authors： Harris RE,Chen-Backlund JY,Wynder EL

更新日期：1990-12-15 00:00:00

abstract：:Results of 567 thin-needle aspiration biopsies of head and neck lesions are reviewed. Cases included lymph nodes, salivary glands, thyroid, soft tissue and bone lesions. For the entire series, 17 patients had unsatisfactory aspirations. There were 12 false negative reports and 4 false positive reports, rates of 2.1% a...

journal_title：Cancer

authors： Frable WJ,Frable MA

更新日期：1979-04-01 00:00:00

abstract：BACKGROUND:The role of prophylactic cranial irradiation (PCI) for patients with limited-stage small cell lung cancer (LSSCLC) remains a controversial issue. This study evaluated PCI in patients with LSSCLC who achieved a complete response to initial chemotherapy. METHODS:A retrospective case study of all nonprotocol p...

journal_title：Cancer

authors： Liengswangwong V,Bonner JA,Shaw EG,Foote RL,Frytak S,Richardson RL,Creagan ET,Eagan RT,Su JQ

更新日期：1995-03-15 00:00:00

abstract：:One hundred two long-term survivors of childhood cancers with second malignant neoplasms (SMNs) were collected from 10 institutions. Forty-seven cases fulfilling study criteria were studied to determine the risk of developing a SMN in irradiated fields after exposure to various chemotherapeutic agents. The case contro...

journal_title：Cancer

authors： D'Angio GJ,Meadows A,Miké V,Harris C,Evans A,Jaffe N,Newton W,Schweisguth O,Sutow W,Morris-Jones P

更新日期：1976-02-01 00:00:00

abstract：:Radiation therapy alone, surgery alone, or the combination of these two modalities, remain the accepted treatments in the management of epidermoid carcinomas of the mucosa of the head and neck. These modalities of therapy produce comparable results; but, radiotherapy alone has the advantage that it can conserve anatom...

journal_title：Cancer

authors： Marcial VA,Pajak TF

更新日期：1985-05-01 00:00:00