Expression of c-erbB-2 oncoprotein in gastric carcinoma. Immunoreactivity for c-erbB-2 protein is an independent indicator of poor short-term prognosis in patients with gastric carcinoma.

abstract：BACKGROUND:Conditional survival (CS) has emerged as a clinically relevant measure of prognosis for cancer survivors. The objective of this analysis was to provide melanoma-specific CS estimates to help clinicians promote more informed patient decision making. METHODS:Patients with melanoma and at least 5 years of foll...

journal_title：Cancer

authors： Xing Y,Chang GJ,Hu CY,Askew RL,Ross MI,Gershenwald JE,Lee JE,Mansfield PF,Lucci A,Cormier JN

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Fatigue is a common and distressing symptom for patients with gynecologic cancers. Few studies have empirically examined whether it spontaneously resolves. This study was aimed at identifying longitudinal patterns of fatigue and predictors of clinically significant fatigue 1 year after treatment completion. ...

journal_title：Cancer

authors： Poort H,de Rooij BH,Uno H,Weng S,Ezendam NPM,van de Poll-Franse L,Wright AA

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:This study analyzed whether proliferative activity and expression of P-glycoprotein 170 (P-170) or glutathione S-transferase-pi (GST-pi) in human non-small cell lung carcinomas (NSCLC) represent independent factors in resistance to doxorubicin or whether an association exists between these factors. METHODS:...

journal_title：Cancer

authors： Volm M,Mattern J,Samsel B

更新日期：1992-08-15 00:00:00

abstract：:Artificial neural networks now are used in many fields. They have become well established as viable, multipurpose, robust computational methodologies with solid theoretic support and with strong potential to be effective in any discipline, especially medicine. For example, neural networks can extract new medical infor...

journal_title：Cancer

authors： Dayhoff JE,DeLeo JM

更新日期：2001-04-15 00:00:00

abstract：BACKGROUND:A novel pancreatic carcinoma cell line, FAMPAC, was identified from investigation of poorly differentiated pancreatic adenocarcinoma cells found in a patient with a familial predisposition to pancreatic carcinoma. A gene responsible for familial pancreatic carcinoma has not been identified to date. METHODS:...

journal_title：Cancer

authors： Eisold S,Ryschich E,Linnebacher M,Giese T,Nauheimer D,Wild A,Bartsch DK,Büchler MW,Schmidt J

更新日期：2004-05-01 00:00:00

abstract：:The therapeutic effect of prednimustine was studied in 35 patients with advanced breast cancer resistant to previous cytotoxic and/or endocrine therapy. Response (PR + CR) was obtained in 14 patients (40%) of a median duration of five months. Among the 14 responding patients, 10 were resistant to previous endocrine th...

journal_title：Cancer

authors： Mouridsen HT,Kristensen D,Nielsen JH,Dombernowsky P

更新日期：1980-07-15 00:00:00

abstract：BACKGROUND:Over the past 2 decades, significant progress has been made in the field of metastatic colorectal cancer (mCRC) regarding new imaging techniques, surgical interventions, and systemic therapy. It is not known whether the benefit from these interventions has extended overall survival (OS) within the general mC...

journal_title：Cancer

authors： Golan T,Urban D,Berger R,Lawrence YR

更新日期：2013-08-15 00:00:00

abstract：:Local and systemic toxicities associated with hepatic arterial infusion of human recombinant tumor necrosis factor (rTNF) were studied in healthy adult mongrel dogs. The animals received saline containing human serum albumin with or without rTNF (0.02, 0.2, or 2.0 mg/m2). Arteriograms were made, and blood samples were...

journal_title：Cancer

authors： Ohkawa S,Wright KC,Mahajan H,Mavligit GM,Wallace S

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Black females have lower breast carcinoma survival rates compared with white females. One possible reason is that black females have more advanced-stage breast disease. Another factor may be racial differences in the utilization of cancer treatments. METHODS:The authors determined racial differences in 6-ye...

journal_title：Cancer

authors： Chu KC,Lamar CA,Freeman HP

更新日期：2003-06-01 00:00:00

abstract：:A number of problems inherent to quality of care evaluation have been described above. Although issues such as limited resources and clinical staff resistance may not be specific to cancer care, they certainly impact on the evaluation of the quality of care offered to cancer patients. Other issues such as complexity o...

journal_title：Cancer

authors： Miransky LJ

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:The importance of the bone marrow microenvironment in multiple myeloma is receiving increasing attention. Recent studies have suggested the importance of cytokine production and cell-cell contact by bone marrow stromal cells in the survival of myeloma cells. METHODS:In the current study, the authors examine...

journal_title：Cancer

authors： Wallace SR,Oken MM,Lunetta KL,Panoskaltsis-Mortari A,Masellis AM

更新日期：2001-04-01 00:00:00

abstract：:The ganglioside composition of neuroblastoma samples from 53 patients was determined. Tumor sites included the adrenals (15), and the thoracic (20), abdominal (15), and pelvic (3) areas. Age of the patients at the time of surgery ranged from 1 day to over 10 years and the Stage of the tumors from A to D. Differences i...

journal_title：Cancer

authors： Schengrund CL,Repman MA,Shochat SJ

更新日期：1985-12-01 00:00:00

abstract：:During the period from September, 1976 to June, 1979, 70 patients with locoregional or extensive epidermoid carcinoma of the esophagus were treated with the two-drug combination of cisplatin and bleomycin (DB). For the 43 patients with locoregional disease (LRD), DB was used prior to surgery and/or radiation therapy; ...

journal_title：Cancer

authors： Coonley CJ,Bains M,Hilaris B,Chapman R,Kelsen DP

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:Ovarian surface epithelial cells are positionally organized as a single cell layer by a sheet of basement membrane. It is believed that the contact of the ovarian surface epithelial cells with the basement membrane regulates cell growth and ensures the organization of the epithelium. Disabled-2 (Dab2), a sig...

journal_title：Cancer

authors： Capo-Chichi CD,Smith ER,Yang DH,Roland IH,Vanderveer L,Cohen C,Hamilton TC,Godwin AK,Xu XX

更新日期：2002-10-15 00:00:00

abstract：:Thrombocytosis above 40.0 X 10(4)/mm3 occurred in five of six (83%) patients with malignant mesothelioma. In contrast, the incidence of thrombocytosis was 7.5% in patients with lung adenocarcinoma, 12.5% in squamous cell carcinoma, 5.1% in small cell carcinoma, and 41.7% in large cell carcinoma, respectively. The plat...

journal_title：Cancer

authors： Nakano T,Fujii J,Tamura S,Hada T,Higashino K

更新日期：1986-10-15 00:00:00

abstract：:Pain management often is difficult in patients with bone metastases. Metastatic disease represents >40% of oncologic practice, and >70% of patients with metastatic disease have uncontrolled cancer-related pain. Significant morbidity caused by pathologic fracture and spinal cord compression can result from untreated bo...

journal_title：Cancer

authors： Janjan NA

更新日期：1997-10-15 00:00:00

abstract：:The most important area in which cancer care and bioethics intersect is in the care of the dying. It is in the shift toward according more control to patients, more choice in the setting in which death will come, and in the willingness to take palliative care and comfort care seriously that bioethics has most usefully...

journal_title：Cancer

authors： Caplan AL

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Patients with aggressive non-Hodgkin lymphoma (NHL) require intensive and extensive therapy, which seems impracticable in elderly patients due to hematologic and extrahematologic toxicity. Consequent dose reduction and therapy attenuation can reduce treatment-related toxicity but also decreases therapeutic e...

journal_title：Cancer

authors： Rigacci L,Carpaneto A,Alterini R,Carrai V,Bernardi F,Bellesi G,Longo G,Bosi A,Rossi Ferrini P

更新日期：2003-01-01 00:00:00

abstract：:In a 10-year incidence survey of breast cancer in the City of Boston, 14 cases in American Chinese women were observed, while approximately 13 were expected on the basis of age-specific incidence in the white population. In Hawaii, on the other hand, while breast cancer incidence rates for ethnic Chinese are approxima...

journal_title：Cancer

authors： Trichopoulos D,Yen S,Brown J,Cole P,MacMahon B

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Although outcomes for patients with squamous cell carcinoma of the anus (SCCA) have improved, the gains in benefit may not be shared uniformly among patients of disparate socioeconomic status. In the current study, the authors investigated whether area-based median household income (MHI) is predictive of sur...

journal_title：Cancer

authors： Lin D,Gold HT,Schreiber D,Leichman LP,Sherman SE,Becker DJ

更新日期：2018-04-15 00:00:00

abstract：:Six patients with Hodgkin's disease (HD) and demonstrable serum antibodies to human immunodeficiency virus (HIV) and two additional patients with HD belonging to HIV-associated high-risk groups but with negative HIV serology were studied. All patients were men and ranged in age from 21 to 45 years. The HIV risk factor...

journal_title：Cancer

authors： Pelstring RJ,Zellmer RB,Sulak LE,Banks PM,Clare N

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Partial nephrectomy (PN) is recommended for localized T1a (≤4 cm) renal masses and is preferred over radical nephrectomy (RN) for amenable T1b/T2 (>4 cm) tumors. The objective of the current study was to assess overall survival (OS) differences between PN and RN in patients with T1 and T2 renal cell carcinom...

journal_title：Cancer

authors： Ristau BT,Handorf EA,Cahn DB,Kutikov A,Uzzo RG,Smaldone MC

更新日期：2018-10-01 00:00:00

abstract：:The purpose of this study was to determine whether the presence of more than 5% blasts in a differential count of cytocentrifuged cerebrospinal fluid (CSF) with less than 6 leukocytes/microliter was predictive of central nervous system (CNS) relapse in children with acute lymphoblastic leukemia (ALL). A double concent...

journal_title：Cancer

authors： Odom LF,Wilson H,Cullen J,Bank J,Blake M,Jamieson B

更新日期：1990-10-15 00:00:00

abstract：:Serum complements, C3, C4, and C3 proactivator (C3PA), were evaluated prospectively for their diagnostic power in detecting hepatocellular carcinoma (HCC) in patients with liver cirrhosis (LC). Sixty-three LC patients, including 36 LC with HCC patients, were recruited for this study during the period from March to Nov...

journal_title：Cancer

authors： Chang WY,Chuang WL

更新日期：1988-07-15 00:00:00

abstract：BACKGROUND:An intensive in-patient Phase II study of continuous infusion recombinant human interleukin-2 (rhIL-2) 3 X 10(6) Roche units (9 MIU/m2)/day plus intramuscular injection of interferon-alpha-2a (rIFN-alpha-2a) 5 x 10(6) U/m2/day, four consecutive days per week, was performed to determine whether four consecuti...

journal_title：Cancer

authors： Eton O,Talpaz M,Lee KH,Rothberg JM,Brell JM,Benjamin RS

更新日期：1996-03-01 00:00:00

abstract：BACKGROUND:Renal medullary carcinoma is a rare tumor that is most common in young black men with sickle cell disease or trait. Patients often present with advanced disease at the time of diagnosis, and their prognosis is poor, even with aggressive therapy. The clinical and pathologic features of renal medullary carcino...

journal_title：Cancer

authors： Assad L,Resetkova E,Oliveira VL,Sun W,Stewart JM,Katz RL,Caraway NP

更新日期：2005-02-25 00:00:00

abstract：:The DNA content of human plasma cells from myeloma patients relative to that of leukocytes was determined by flow and microscopic cytofluorometry after propidium iodide and fluorescent Feulgen staining, respectively. Mononucleated myeloma plasma cells from all of the 17 patients studied contained more DNA (17 to 58%) ...

journal_title：Cancer

authors： Brox L,Mowles D,Pollock B,Belch A

更新日期：1981-05-15 00:00:00

abstract：:Cytopathologists recognize that certain Pap smear findings are suspicious for endometrial pathology in menopausal women. To study their prognostic importance in the directed cervical smear, six parameters were used to evaluate smears for evidence of an endometrial lesion: the presence of (1) histiocytes, (2) multinucl...

journal_title：Cancer

authors： Zucker PK,Kasdon EJ,Feldstein ML

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Idarubicin (IDR), an anthracycline that is a derivative of daunorubicin, was synthesized in an attempt to find new analogs of daunorubicin with an improved spectrum of activity and diminished acute or chronic toxicity. Because of the favorable pharmacokinetic profile of IDR (with the persistence of its activ...

journal_title：Cancer

authors： Arndt CA,Krailo MD,Steinherz L,Scheithauer B,Liu-Mares W,Reaman GH

更新日期：1998-08-15 00:00:00

abstract：BACKGROUND:Helicobacter pylori infection is a risk factor for gastric carcinogenesis. High dietary vitamin C intake appears to protect against gastric carcinoma. It has been suggested that vitamin C exerts the protective effect by scavenging free radicals that may be enhanced by H. pylori. However, vitamin C has not be...

journal_title：Cancer

authors： Zhang HM,Wakisaka N,Maeda O,Yamamoto T

更新日期：1997-11-15 00:00:00