Malignant epithelial tumors in the minor salivary glands, the submandibular gland, and the sublingual gland. Prognostic factors and treatment results.

Abstract:

:Ninety-five malignant tumors in the submandibular gland, the sublingual gland, and the minor salivary glands seen in a 25-year period were reviewed. The patients were retrospectively staged using the Union Internationale Contre le Cancer (UICC) classification. The most frequent tumor was adenoid cystic carcinoma, followed by adenocarcinoma. The submandibular gland was the most frequent location. Five-year and 10-year crude survival rates were 62% and 43%, respectively. Clinical stage was the most important prognostic factor. Survival was not correlated with location of tumor, although recurrence and metastases occurred more frequently in patients with cancer of the submandibular gland. Histologically, the 5-year and 10-year survival was significantly better for patients with adenoid cystic carcinoma compared with the other types; however, although still significant, this difference diminished at 10 years, confirming the need for a long observation time for patients with this tumor.

journal_name

Cancer

journal_title

Cancer

authors

Andersen LJ,Therkildsen MH,Ockelmann HH,Bentzen JD,Schiødt T,Hansen HS

doi

10.1002/1097-0142(19911201)68:11<2431::aid-cncr282

subject

Has Abstract

pub_date

1991-12-01 00:00:00

pages

2431-7

issue

11

eissn

0008-543X

issn

1097-0142

journal_volume

68

pub_type

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